Celiac disease: A review

JAMA Pediatrics

Volumn 168, Issue 3, 2014, Pages 272-278

  Guandalini, Stefano ^a,b,c   Assiri, Asaad ^b  

^a UNIVERSITY OF CHICAGO   (United States)

^b KING SAUD UNIVERSITY   (Saudi Arabia)

^c University of Chicago Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTEN;

ABDOMINAL DISTENSION; ANEMIA; APHTHOUS ULCER; ARTHRITIS; CELIAC DISEASE; CHILD NUTRITION; CHRONIC DIARRHEA; CLINICAL FEATURE; DERMATITIS HERPETIFORMIS; ENAMEL HYPOPLASIA; ENTEROPATHY; FAILURE TO THRIVE; FEMALE INFERTILITY; GASTROINTESTINAL TRACT; GLUTEN FREE DIET; HUMAN; HYPERTRANSAMINASEMIA; INTESTINE BIOPSY; MEDICATION COMPLIANCE; NEUROLOGIC DISEASE; OSTEOPOROSIS; PATHOGENESIS; PREVALENCE; PRIORITY JOURNAL; QUALITY OF LIFE; REVIEW; SCREENING TEST; SEROLOGY; SHORT STATURE;

ADOLESCENT; CELIAC DISEASE; CHILD; FOOD HYPERSENSITIVITY; GLUTENS; HUMANS; QUALITY OF LIFE;

EID: 84896783941     PISSN: 21686203     EISSN: None     Source Type: Journal    
DOI: 10.1001/jamapediatrics.2013.3858     Document Type: Review

References (87)

1. Husby S, Koletzko S, Korponay-Szabó IR, et al; ESPGHAN Working Group on Coeliac Disease Diagnosis; ESPGHAN Gastroenterology Committee; European Society for Pediatric Gastroenterology, Hepatology, and Nutrition. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease. J Pediatr Gastroenterol Nutr. 2012;54(1):136-160.
2. Ludvigsson JF, Leffler DA, Bai JC, et al. The Oslo definitions for coeliac disease and related terms. Gut. 2013;62(1):43-52.
3. Gee SJ. On the celiac affection. St Bartholomew's Hosp Rep. 1888;24:17-20.
4. van Berge-Henegouwen GP, Mulder CJ. Pioneer in the gluten free diet: Willem-Karel Dicke 1905-1962, over 50 years of gluten free diet. Gut. 1993;34(11):1473-1475.
5. Hill ID, Dirks MH, Liptak GS, et al; North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. J Pediatr Gastroenterol Nutr. 2005;40(1):1-19.
6. Dydensborg S, Toftedal P, Biaggi M, Lillevang ST, Hansen DG, Husby S. Increasing prevalence of coeliac disease in Denmark: a linkage study combining national registries. Acta Paediatr. 2012;101(2):179-184.
7. Vilppula A, Kaukinen K, Luostarinen L, et al. Increasing prevalence and high incidence of celiac disease in elderly people: a population-based study. BMC Gastroenterol. 2009;9:e49. doi:10.1186/1471-230X-9-49.
8. Lohi S, Mustalahti K, Kaukinen K, et al. Increasing prevalence of coeliac disease over time. Aliment Pharmacol Ther. 2007;26(9):1217-1225.
9. Mustalahti K, Catassi C, Reunanen A, et al; Coeliac EU Cluster, Project Epidemiology. The prevalence of celiac disease in Europe: results of a centralized, international mass screening project. Ann Med. 2010;42(8):587-595.
10. Catassi C, Kryszak D, Bhatti B, et al. Natural history of celiac disease autoimmunity in a USA cohort followed since 1974. Ann Med. 2010;42(7):530-538.
11. Ludvigsson JF, Rubio-Tapia A, van Dyke CT, et al. Increasing incidence of celiac disease in a North American population. Am J Gastroenterol. 2013;108(5):818-824.
12. White LE, Merrick VM, Bannerman E, et al. The rising incidence of celiac disease in Scotland. Pediatrics. 2013;132(4):e924-e931. doi:10.1542/peds.2013- 0932.
13. Rubio-Tapia A, Kyle RA, Kaplan EL, et al. Increased prevalence and mortality in undiagnosed celiac disease. Gastroenterology. 2009;137(1): 88-93.
14. Myléus A, Hernell O, Gothefors L, et al. Early infections are associated with increased risk for celiac disease: an incident case-referent study. BMC Pediatr. 2012;12:194.
15. Lionetti E, Castellaneta S, Pulvirenti A, et al; Italian Working Group of Weaning and Celiac Disease Risk. Prevalence and natural history of potential celiac disease in at-family-risk infants prospectively investigated from birth. J Pediatr. 2012;161(5):908-914.
16. Rubio-Tapia A, Ludvigsson JF, Brantner TL, Murray JA, Everhart JE. The prevalence of celiac disease in the United States. Am J Gastroenterol. 2012;107(10):1538-1545.
17. Reilly NR, Fasano A, Green PH. Presentation of celiac disease. Gastrointest Endosc Clin N Am. 2012;22(4):613-621.
18. Collado MC, Donat E, Ribes-Koninckx C, Calabuig M, Sanz Y. Specific duodenal and faecal bacterial groups associated with paediatric coeliac disease. J Clin Pathol. 2009;62(3):264-269.
19. De Palma G, Nadal I, Medina M, et al. Intestinal dysbiosis and reduced immunoglobulin-coated bacteria associated with coeliac disease in children. BMC Microbiol. 2010;10:63.
20. Ivarsson A, Myléus A, Norström F, et al. Prevalence of childhood celiac disease and changes in infant feeding. Pediatrics. 2013;131(3):e687- e694.
21. Norris JM, Barriga K, Hoffenberg EJ, et al. Risk of celiac disease autoimmunity and timing of gluten introduction in the diet of infants at increased risk of disease. JAMA. 2005;293(19):2343-2351.
22. Molberg O, Kett K, Scott H, Thorsby E, Sollid LM, Lundin KE. Gliadin specific, HLA DQ2-restricted T cells are commonly found in small intestinal biopsies from coeliac disease patients, but not from controls. Scand J Immunol. 1997;46(3):103-109.
23. Hausch F, Shan L, Santiago NA, Gray GM, Khosla C. Intestinal digestive resistance of immunodominant gliadin peptides. Am J Physiol Gastrointest Liver Physiol. 2002;283(4):G996- G1003.
24. Sollid LM. Molecular basis of celiac disease. Annu Rev Immunol. 2000;18:53-81.
25. Abadie V, Sollid LM, Barreiro LB, Jabri B. Integration of genetic and immunological insights into a model of celiac disease pathogenesis. Annu Rev Immunol. 2011;29:493-525.
26. Marsh MN. Gluten, major histocompatibility complex, and the small intestine: a molecular and immunobiologic approach to the spectrum of gluten sensitivity ("celiac sprue"). Gastroenterology. 1992;102(1):330-354.
27. Oberhuber G. Histopathology of celiac disease. Biomed Pharmacother. 2000;54(7):368-372.
28. Giersiepen K, Lelgemann M, Stuhldreher N, et al; ESPGHAN Working Group on Coeliac Disease Diagnosis. Accuracy of diagnostic antibody tests for coeliac disease in children: summary of an evidence report. J Pediatr Gastroenterol Nutr. 2012;54(2):229-241.
29. Schwertz E, Kahlenberg F, Sack U, et al. Serologic assay based on gliadin-related nonapeptides as a highly sensitive and specific diagnostic aid in celiac disease. Clin Chem. 2004;50(12):2370-2375.
30. Amarri S, Alvisi P, De Giorgio R, et al. Antibodies to deamidated gliadin peptides: an accurate predictor of coeliac disease in infancy. J Clin Immunol. 2013;33(5):1027-1030.
31. Roma E, Panayiotou J, Karantana H, et al. Changing pattern in the clinical presentation of pediatric celiac disease: a 30-year study. Digestion. 2009;80(3):185-191.
32. Mäki M, Kallonen K, Lähdeaho ML, Visakorpi JK. Changing pattern of childhood coeliac disease in Finland. Acta Paediatr Scand. 1988;77(3):408-412.
33. Telega G, Bennet TR,Werlin S. Emerging new clinical patterns in the presentation of celiac disease. Arch Pediatr Adolesc Med. 2008;162(2):164-168.
34. Andersen DH. Celiac syndrome: the relationship of celiac disease, starch intolerance, and steatorrhea. J Pediatr. 1947;30(5):564-582.
35. Benson GD, Kowlessar OD, Sleisenger MH. Adult celiac disease with emphasis upon response to the gluten-free diet. Medicine (Baltimore). 1964;43:1-40.
36. D'Amico MA, Holmes J, Stavropoulos SN, et al. Presentation of pediatric celiac disease in the United States: prominent effect of breastfeeding. Clin Pediatr (Phila). 2005;44(3):249-258.
37. Rivera E, Assiri A, Guandalini S. Celiac disease. Oral Dis. 2013;19(7):635-641.
38. Rashid M, Cranney A, Zarkadas M, et al. Celiac disease: evaluation of the diagnosis and dietary compliance in Canadian children. Pediatrics. 2005;116(6):e754-e759.
39. Ehsani-Ardakani MJ, Rostami Nejad M, Villanacci V, et al. Gastrointestinal and non-gastrointestinal presentation in patients with celiac disease. Arch Iran Med. 2013;16(2):78-82.
40. Bottaro G, Cataldo F, Rotolo N, Spina M, Corazza GR. The clinical pattern of subclinical/silent celiac disease: an analysis on 1026 consecutive cases. Am J Gastroenterol. 1999;94(3):691-696.
41. Harper JW, Holleran SF, Ramakrishnan R, Bhagat G, Green PH. Anemia in celiac disease is multifactorial in etiology. Am J Hematol. 2007;82(11):996- 1000.
42. Hin H, Bird G, Fisher P, Mahy N, Jewell D. Coeliac disease in primary care: case finding study. BMJ. 1999;318(7177):164-167.
43. Kolho KL, Färkkilä MA, Savilahti E. Undiagnosed coeliac disease is common in Finnish adults. Scand J Gastroenterol. 1998;33(12):1280- 1283.
44. Lo W, Sano K, Lebwohl B, Diamond B, Green PH. Changing presentation of adult celiac disease. Dig Dis Sci. 2003;48(2):395-398.
45. Rashid M, Zarkadas M, Anca A, Limeback H. Oral manifestations of celiac disease: a clinical guide for dentists. J Can Dent Assoc. 2011;77:b39.
46. Wierink CD, van Diermen DE, Aartman IH, Heymans HS. Dental enamel defects in children with coeliac disease. Int J Paediatr Dent. 2007;17:163-168.
47. Cheng J, Malahias T, Brar P, Minaya MT, Green PH. The association between celiac disease, dental enamel defects, and aphthous ulcers in a United States cohort. J Clin Gastroenterol. 2010;44(3):191-194.
48. Campisi G, Di Liberto C, Carroccio A, et al. Coeliac disease: oral ulcer prevalence, assessment of risk and association with gluten-free diet in children. Dig Liver Dis. 2008;40(2):104-107.
49. Kavak US, Yüce A, Koçak N, et al. Bone mineral density in children with untreated and treated celiac disease. J Pediatr Gastroenterol Nutr. 2003;37(4):434-436.
50. Mora S, Barera G, Ricotti A, Weber G, Bianchi C, Chiumello G. Reversal of low bone density with a gluten-free diet in children and adolescents with celiac disease. Am J Clin Nutr. 1998;67(3):477-481.
51. Mora S, Barera G, Beccio S, et al. A prospective, longitudinal study of the long-term effect of treatment on bone density in children with celiac disease. J Pediatr. 2001;139(4):516-521.
52. Motta ME, Faria ME, Silva GA. Prevalence of low bone mineral density in children and adolescents with celiac disease under treatment. Sao Paulo Med J. 2009;127(5):278-282.
53. Fouda MA, Khan AA, Sultan MS, Rios LP, McAssey K, Armstrong D. Evaluation and management of skeletal health in celiac disease: position statement. Can J Gastroenterol. 2012;26(11):819-829.
54. Farre C, Esteve M, Curcoy A, et al. Hypertransaminasemia in pediatric celiac disease patients and its prevalence as a diagnostic clue. Am J Gastroenterol. 2002;97(12):3176-3181.
55. Di Biase AR, Colecchia A, Scaioli E, et al. Autoimmune liver diseases in a paediatric population with coeliac disease: a 10-year single-centre experience. Aliment Pharmacol Ther. 2010;31(2):253-260.
56. Lubrano E, Ciacci C, Ames PR, Mazzacca G, Oriente P, Carpa R. The arthritis of celiac disease: prevalence and pattern in 200 adult patients. Br J Rheumatol. 1996;35:1314-1318.
57. Iqbal T, Zaidi MA, Wells GA, Karsh J. Celiac disease arthropathy and autoimmunity study. J Gastroenterol Hepatol. 2013;28(1):99-105.
58. Ludvigsson JF, Sellgren C, Runeson B, Långström N, Lichtenstein P. Increased suicide risk in coeliac disease: a Swedish nationwide cohort study. Dig Liver Dis. 2011;43(8):616-622.
59. Pynnönen PA, Isometsä ET, Verkasalo MA, et al. Gluten-free dietmay alleviate depressive and behavioural symptoms in adolescents with coeliac disease: a prospective follow-up case-series study. BMC Psychiatry. 2005;5:14.
60. Salardi S, Volta U, Zucchini S, et al. Prevalence of celiac disease in children with type 1 diabetes mellitus increased in themid-1990s: an 18-year longitudinal study based on anti-endomysial antibodies. J Pediatr Gastroenterol Nutr. 2008;46(5):612-614.
61. Elfström P, Montgomery SM, Kämpe O, Ekbom A, Ludvigsson JF. Risk of primary adrenal insufficiency in patients with celiac disease. J Clin Endocrinol Metab. 2007;92(9):3595-3598.
62. Ludvigsson JF, Hemminki K,Wahlström J, Almqvist C. Celiac disease confers a 1.6-fold increased risk of asthma: a nationwide population-based cohort study. J Allergy Clin Immunol. 2011;127(4):1071-1073.
63. Welander A, Sundelin B, ForedM, Ludvigsson JF. Increased risk of IgA nephropathy among individuals with celiac disease. J Clin Gastroenterol. 2013;47(8):678-683.
64. Ludvigsson JF, Rubio-Tapia A, Chowdhary V, Murray JA, Simard JF. Increased risk of systemic lupus erythematosus in 29,000 patients with biopsy-verified celiac disease. J Rheumatol. 2012;39(10):1964-1970.
65. Sadr-Azodi O, Sanders DS, Murray JA, Ludvigsson JF. Patients with celiac disease have an increased risk for pancreatitis. Clin Gastroenterol Hepatol. 2012;10(10):1136-1142.e3. doi: 10.1016/j.cgh.2012.06.023.
66. Ludvigsson JF, Kämpe O, Lebwohl B, Green PH, Silverberg SJ, Ekbom A. Primary hyperparathyroidism and celiac disease: a population-based cohort study. J Clin Endocrinol Metab. 2012;97(3):897-904.
67. Stephansson O, Falconer H, Ludvigsson JF. Risk of endometriosis in 11,000 women with celiac disease. Hum Reprod. 2011;26(10):2896-2901.
68. Mollazadegan K, Kugelberg M, Lindblad BE, Ludvigsson JF. Increased risk of cataract among 28,000 patients with celiac disease. Am J Epidemiol. 2011;174(2):195-202.
69. Ludvigsson JF, James S, Askling J, Stenestrand U, Ingelsson E. Nationwide cohort study of risk of ischemic heart disease in patients with celiac disease. Circulation. 2011;123(5):483-490.
70. Emilsson L, Andersson B, Elfström P, Green PH, Ludvigsson JF. Risk of idiopathic dilated cardiomyopathy in 29 000 patients with celiac disease. J AmHeart Assoc. 2012;1(3):e001594. doi: 10.1161/JAHA.112.001594.
71. De Marchi S, Chiarioni G, Prior M, Arosio E. Young adults with coeliac disease may be at increased risk of early atherosclerosis. Aliment Pharmacol Ther. 2013;38(2):162-169.
72. Ludvigsson JF, West J, Hubbard R, Card T. Neutral risk of lung cancer in adults with celiac disease: nationwide cohort study. Lung Cancer. 2012;78(3):179-184.
73. Ludvigsson JF, West J, Ekbom A, Stephansson O. Reduced risk of breast, endometrial and ovarian cancer in women with celiac disease. Int J Cancer. 2012;131(3):244-250.
74. Rubio-Tapia A, Hill ID, Kelly CP, Calderwood AH, Murray JA; American College of Gastroenterology. ACG clinical guidelines: diagnosis and management of celiac disease. Am J Gastroenterol. 2013;108(5):656-677.
75. Barbato M, Maiella G, Di Camillo C, et al. The anti-deamidated gliadin peptide antibodies unmask celiac disease in small children with chronic diarrhoea. Dig Liver Dis. 2011;43(6):465-469.
76. Lebwohl B, Rubio-Tapia A, Assiri A, Newland C, Guandalini S. Diagnosis of celiac disease. Gastrointest Endosc Clin N Am. 2012;22(4):661-677.
77. Rosinach M, Esteve M, González C, et al. Lymphocytic duodenosis: aetiology and long-term response to specific treatment. Dig Liver Dis. 2012;44(8):643-648.
78. Vande Voort JL, Murray JA, Lahr BD, et al. Lymphocytic duodenosis and the spectrum of celiac disease. Am J Gastroenterol. 2009;104(1):142-148.
79. Shmidt E, Smyrk TC, Faubion WA, Oxentenko AS. Duodenal intraepithelial lymphocytosis with normal villous architecture in pediatric patients: Mayo Clinic experience, 2000-2009. J Pediatr Gastroenterol Nutr. 2013;56(1):51-55.
80. Guandalini S, Newland C. Diagnosis of Celiac DiseaseWith the New ESPGHAN Guidelines: Can We Really Skip the Biopsy? Chicago, IL: University of Chicago Celiac Disease Center; 2013.
81. Megiorni F, Pizzuti A. HLA-DQA1 and HLA-DQB1 in celiac disease predisposition: practical implications of the HLA molecular typing. J Biomed Sci. 2012;19:88.
82. Norström F, Sandström O, Lindholm L, Ivarsson A. A gluten-free diet effectively reduces symptoms and health care consumption in a Swedish celiac disease population. BMC Gastroenterol. 2012;12:125.
83. Panzer RM, Dennis M, Kelly CP, Weir D, Leichtner A, Leffler DA. Navigating the gluten-free diet in college. J Pediatr Gastroenterol Nutr. 2012;55(6):740-744.
84. Kautto E, Ivarsson A, Norström F, Högberg L, Carlsson A, Hörnell A. Nutrient intake in adolescent girls and boys diagnosed with coeliac disease at an early age is mostly comparable to their non-coeliac contemporaries [published onlineMay 25, 2013]. J Hum Nutr Diet. doi:10.1111/jhn.12125.
85. de Lorenzo CM, Xikota JC, Wayhs MC, Nassar SM, de Souza Pires MM. Evaluation of the quality of life of children with celiac disease and their parents: a case-control study. Qual Life Res. 2012;21(1):77-85.
86. Ukkola A, Mäki M, Kurppa K, et al. Patients' experiences and perceptions of living with coeliac disease: implications for optimizing care. J Gastrointestin Liver Dis. 2012;21(1):17-22.
87. Herman ML, Rubio-Tapia A, Lahr BD, Larson JJ, Van Dyke CT, Murray JA. Patients with celiac disease are not followed up adequately. Clin Gastroenterol Hepatol. 2012;10(8):893-899.e1. doi: 10.1016/j.cgh.2012.05.007.