Duodenal intraepithelial lymphocytosis with normal villous architecture in pediatric patients: Mayo clinic experience, 2000-2009

Journal of Pediatric Gastroenterology and Nutrition

Volumn 56, Issue 1, 2013, Pages 51-55

  Shmidt, Eugenia ^a   Smyrk, Thomas C ^a   Faubion, William A ^a   Oxentenko, Amy S ^a  

^a MAYO CLINIC   (United States)

Author keywords

celiac disease; intraepithelial lymphocytosis; small bowel biopsy

Indexed keywords

ACETYLSALICYLIC ACID; CYCLOOXYGENASE 2 INHIBITOR; LEUKOCYTE ANTIGEN; NONSTEROID ANTIINFLAMMATORY AGENT;

ADOLESCENT; ARTICLE; AUTOIMMUNE DISEASE; CELIAC DISEASE; CELLULAR DISTRIBUTION; CHILD; CLINICAL ARTICLE; CLINICAL FEATURE; CROHN DISEASE; DISEASE ASSOCIATION; DUODENAL INTRAEPITHELIAL LYMPHOCYTOSIS; DUODENUM DISEASE; ENTERITIS; FEMALE; HAPLOTYPE; HELICOBACTER INFECTION; HISTOLOGY; HODGKIN DISEASE; HUMAN; INTESTINE BIOPSY; LYMPHOCYTE; LYMPHOCYTOSIS; MALE; PRESCHOOL CHILD; PREVALENCE; PRIORITY JOURNAL; SCHOOL CHILD; SEROLOGY; ULCERATIVE COLITIS;

ADOLESCENT; AUTOIMMUNE DISEASES; CELIAC DISEASE; CHILD; CHILD, PRESCHOOL; DUODENUM; FEMALE; HELICOBACTER INFECTIONS; HUMANS; INFANT; INFLAMMATORY BOWEL DISEASES; INTESTINAL MUCOSA; LYMPHOCYTES; LYMPHOCYTOSIS; MALE; REFERENCE VALUES;

HELICOBACTER PYLORI;

EID: 84872606824     PISSN: 02772116     EISSN: 15364801     Source Type: Journal    
DOI: 10.1097/MPG.0b013e318267c353     Document Type: Article

References (12)

1. Marsh MN. Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue'). Gastroenterology 1992;102:330-54.
2. Marsh MN, Bjarnason I, Shaw J, et al. Studies of intestinal lymphoid tissue. XIV-HLA status, mucosal morphology, permeability and epithelial lymphocyte populations in first degree relatives of patients with coeliac disease. Gut 1990;31:32-6.
3. Memeo L, Jhang J, Hibshoosh H, et al. Duodenal intraepithelial lymphocytosis with normal villous architecture: common occurrence in H pylori gastritis. Mod Pathol 2005;18:1134-44.
4. Carmack SW, Lash RH, Gulizia JM, et al. Lymphocytic disorders of the gastrointestinal tract; a review for the practicing pathologist. Adv Anat Pathol 2009;16:290-306.
5. Kakar] S, Nehra V, Murray HA, et al. Significance of intraepithelial lymphocytosis in small bowel biopsy samples with normal mucosal architecture. Am J Gastroenterol 2003;98: 2027-33.
6. Hill ID, Dirks MH, Liptak GS, et al. Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. J Pediatr Gastroenterol Nutr 2005;40:1-19.
7. Wright CL, Riddell RH. Histology of the stomach and duodenum in Crohn's disease. Am J Surg Pathol 1998;22:383-90.
8. Lähdeaho ML, Kaukinen K, Collin P, et al. Celiac disease: from inflammation to atrophy: a long-term follow-up study. J Pediatr Gastroenterol Nutr 2005;41:44-8.
9. Hill PG, Holmes GKT. Coeliac disease: a biopsy is not always necessary for diagnosis. Aliment Pharmacol Ther 2008;27:572-77.
10. Goldstein NS, Underhill J. Morphologic features suggestive of gluten sensitivity in architecturally normal duodenal biopsy specimens. Am J Clin Pathol 2001;116:63-71.
11. Bonamico M, Mariani P, Thanasi E, et al. Patchy villous atrophy of the duodenum in childhood celiac disease. J Pediatr Gastroenterol Nutr 2004;38:204-7.
12. Bonamico M, Thanasi E, Mariani P, et al. Duodenal bulb biopsies in celiac disease: a multicenter study. J Pediatr Gastroenterol Nutr 2008;47:5:618-22.