Monocyte Chemotactic Protein 1 (MCP-1) modulates pro- survival signaling to promote progression of head and neck squamous cell carcinoma

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Ji, Wen Tsai ^a   Chen, Hau Ren ^a   Lin, Chun Hsuan ^b   Lee, Jeng Woei ^c   Lee, Ching Chih ^b,c  

^a NATIONAL CHUNG CHENG UNIVERSITY   (Taiwan)

^b DALIN TZU CHI HOSPITAL   (Taiwan)

^c TZU CHI UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN KINASE B; RECOMBINANT PROTEIN; STAT3 PROTEIN; CCL2 PROTEIN, HUMAN;

ADULT; ARTICLE; CANCER DIAGNOSIS; CANCER GRADING; CANCER GROWTH; CANCER PATIENT; CANCER PROGNOSIS; CANCER RESISTANCE; CANCER SURVIVAL; CARCINOMA CELL; CELL DEATH; CLINICAL ARTICLE; CONTROLLED STUDY; DISTANT METASTASIS; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; GROWTH INHIBITION; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MIDDLE AGED; OUTCOME ASSESSMENT; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SERUM; SIGNAL TRANSDUCTION; SURVIVAL TIME; WESTERN BLOTTING; AGED; APOPTOSIS; CELL SURVIVAL; DISEASE COURSE; DOSE RESPONSE; DRUG EFFECTS; HEAD AND NECK TUMOR; METABOLISM; MORTALITY; PATHOLOGY; SQUAMOUS CELL CARCINOMA; SURVIVAL; TUMOR CELL CULTURE;

ADULT; AGED; APOPTOSIS; CARCINOMA, SQUAMOUS CELL; CELL SURVIVAL; CHEMOKINE CCL2; DISEASE PROGRESSION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MAP KINASE SIGNALING SYSTEM; MIDDLE AGED; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; SURVIVAL ANALYSIS; TUMOR CELLS, CULTURED;

EID: 84896757433     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0088952     Document Type: Article

References (42)

1. Parkin DM, Bray F, Ferlay J, Pisani P (2005) Global cancer statistics, 2002. CA: a cancer journal for clinicians 55: 74-108. (Pubitemid 40372904)
2. Liao YM, Kim C, Yen Y (2011) Mammalian target of rapamycin and head and neck squamous cell carcinoma. Head Neck Oncol 3.
3. Tabuchi K, Nakayama M, Nishimura B, Hayashi K, Hara A (2011) Early detection of nasopharyngeal carcinoma. International journal of otolaryngology 2011: 638058.
4. Cripps C, Winquist E, Devries MC, Stys-Norman D, Gilbert R, et al. (2010) Epidermal growth factor receptor targeted therapy in stages III and IV head and neck cancer. Curr Oncol 17: 37-48.
5. Boslooper K, Lam AKY, Gao J, Weinstein S, Johnson N (2008) The clinicopathological roles of alpha-B-crystallin and p53 expression in patients with head and neck squamous cell carcinoma. Pathology 40: 500-504. (Pubitemid 351950887)
6. Gingras AC, Kennedy SG, O'Leary MA, Sonenberg N, Hay N (1998) 4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway. Gene Dev 12: 502-513. (Pubitemid 28101013)
7. Gordon MD, Nusse R (2006) Wnt signaling: Multiple pathways, multiple receptors, and multiple transcription factors. Journal of Biological Chemistry 281: 22429-22433.
8. Blankesteijn WM, de Schans VAMV, ter Horst P, Smits JFM (2008) The Wnt/frizzled/GSK-3 beta pathway: a novel therapeutic target for cardiac hypertrophy. Trends Pharmacol Sci 29: 175-180.
9. Gregory MA, Qi Y, Hann SR (2003) Phosphorylation by glycogen synthase kinase-3 controls c-Myc proteolysis and subnuclear localization. Journal of Biological Chemistry 278: 51606-51612. (Pubitemid 38020405)
10. Zhou BHP, Deng J, Xia WY, Xu JH, Li YM, et al. (2004) Dual regulation of Snail by GSK-3 beta-mediated phosphorylation in control of epithelial- mesenchymal transition. Nat Cell Biol 6: 931-+.
11. Datta SR, Dudek H, Tao X, Masters S, Fu HA, et al. (1997) Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91: 231-241. (Pubitemid 27456390)
12. Zhou HL, Li XM, Meinkoth J, Pittman RN (2000) Akt regulates cell survival and apoptosis at a postmitochondrial level. Journal of Cell Biology 151: 483-494.
13. Lu X, Law BK, Chytil AM, Brown KA, Aakre ME, et al. (2004) Activation of the Erk pathway is required for TGF-beta 1-induced EMT in vitro. Neoplasia 6: 603-610. (Pubitemid 39411098)
14. Roberts PJ, Der CJ (2007) Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene 26: 3291-3310. (Pubitemid 46763022)
15. Timofeeva OA, Tarasova NI, Zhang X, Chasovskikh S, Cheema AK, et al. (2013) STAT3 suppresses transcription of proapoptotic genes in cancer cells with the involvement of its N-terminal domain. Proceedings of the National Academy of Sciences of the United States of America 110: 1267-1272.
16. Adachi M, Cui C, Dodge CT, Bhayani MK, Lai SY (2012) Targeting STAT3 inhibits growth and enhances radiosensitivity in head and neck squamous cell carcinoma. Oral oncology 48: 1220-1226.
17. Albanell J, Codony-Servat J, Rojo F, Del Campo JM, Sauleda S, et al. (2001) Activated extracellular signal-regulated kinases: association with epidermal growth factor receptor/transforming growth factor alpha expression in head and neck squamous carcinoma and inhibition by anti-epidermal growth factor receptor treatments. Cancer research 61: 6500-6510. (Pubitemid 32783257)
18. Lee TL, Yeh J, Van Waes C, Chen Z (2006) Epigenetic modification of SOCS-1 differentially regulates STAT3 activation in response to interleukin-6 receptor and epidermal growth factor receptor signaling through JAK and/or MEK in head and neck squamous cell carcinomas. Molecular cancer therapeutics 5: 8-19.
19. Moral M, Paramio JM (2008) Akt pathway as a target for therapeutic intervention in HNSCC. Histology and Histopathology 23: 1269-1278.
20. Sen M, Joyce S, Panahandeh M, Li C, Thomas SM, et al. (2012) Targeting Stat3 abrogates EGFR inhibitor resistance in cancer. Clin Cancer Res 18: 4986-4996.
21. Lu HT, Ouyang WM, Huang CS (2006) Inflammation, a key event in cancer development. Mol Cancer Res 4: 221-233.
22. MacManus CF, Pettigrew J, Seaton A, Wilson C, Maxwell PJ, et al. (2007) Interleukin-8 signaling promotes translational regulation of cyclin D in androgen-independent prostate cancer cells. Mol Cancer Res 5: 737-748. (Pubitemid 47105492)
23. Hideshima T, Nakamura N, Chauhan D, Anderson KC (2001) Biologic sequelae of interleukin-6 induced PI3-K/Akt signaling in multiple myeloma. Blood 98: 639a-639a.
24. Benoy IH, Salgado R, Van Dam P, Geboers K, Van Marck E, et al. (2004) Increased serum interleukin-8 in patients with early and metastatic breast cancer correlates with early dissemination and survival. Clinical Cancer Research 10: 7157-7162. (Pubitemid 39487700)
25. Nakashima J, Tachibana M, Horiguchi Y, Oya M, Ohigashi T, et al. (2000) Serum interleukin 6 as a prognostic factor in patients with prostate cancer. Clinical Cancer Research 6: 2702-2706. (Pubitemid 30482107)
26. Ravishankaran P, Karunanithi R (2011) Clinical significance of preoperative serum interleukin-6 and C-reactive protein level in breast cancer patients. World J Surg Oncol 9.
27. Deshmane SL, Kremlev S, Amini S, Sawaya BE (2009) Monocyte Chemoattractant Protein-1 (MCP-1): An Overview. J Interf Cytok Res 29: 313-326.
28. Salcedo R, Ponce ML, Young HA, Wasserman K, Ward JM, et al. (2000) Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression. Blood 96: 34-40. (Pubitemid 30456447)
29. Loberg RD, Day LL, Harwood J, Ying C, John LNS, et al. (2006) CCL2 is a potent regulator of prostate cancer cell migration and proliferation. Neoplasia 8: 578-586. (Pubitemid 44061313)
30. Koga M, Kai H, Egami K, Murohara T, Ikeda A, et al. (2008) Mutant MCP-1 therapy inhibits tumor angiogenesis and growth of malignant melanoma in mice. Biochemical and biophysical research communications 365: 279-284. (Pubitemid 350137285)
31. Yoshimura T, Howard OM, Ito T, Kuwabara M, Matsukawa A, et al. (2013) Monocyte chemoattractant protein-1/CCL2 produced by stromal cells promotes lung metastasis of 4T1 murine breast cancer cells. PloS one 8: e58791.
32. Chen Z, Malhotra PS, Thomas GR, Ondrey PG, Duffey DC, et al. (1999) Expression of proinflammatory and proangiogenic cytokines in patients with head and neck cancer. Clinical Cancer Research 5: 1369-1379. (Pubitemid 29282941)
33. Huang TT, Chen JY, Tseng CE, Su YC, Ho HC, et al. (2010) Decreased GRP78 protein expression is a potential prognostic marker of oral squamous cell carcinoma in Taiwan. Journal of the Formosan Medical Association = Taiwan yi zhi 109: 326-337.
34. Lee CC, Ho HC, Lee MS, Hung SK, Yu CC, et al. (2010) Expression of haptoglobin predicts recurrence in head and neck squamous cell carcinoma. Clinica chimica acta; international journal of clinical chemistry 411: 1116-1121.
35. Tse KP, Tsang NM, Chen KD, Li HP, Liang Y, et al. (2007) MCP-1 Promoter Polymorphism at 2518 is associated with metastasis of nasopharyngeal carcinoma after treatment. Clinical cancer research: an official journal of the American Association for Cancer Research 13: 6320-6326.
36. Wolff HA, Rolke D, Rave-Frank M, Schirmer M, Eicheler W, et al. (2011) Analysis of chemokine and chemokine receptor expression in squamous cell carcinoma of the head and neck (SCCHN) cell lines. Radiat Environ Bioph 50: 145-154.
37. Barry SP, Davidson SM, Townsend PA (2008) Molecular regulation of cardiac hypertrophy. Int J Biochem Cell B 40: 2023-2039.
38. Caers J, Van Valckenborgh E, Menu E, Van Camp B, Vanderkerken K (2008) Unraveling the biology of multiple myeloma disease: cancer stem cells, acquired intracellular changes and interactions with the surrounding micro-environment. B Cancer 95: 301-313. (Pubitemid 351528767)
39. Pan YB, Claret FX (2012) Targeting Jab1/CSN5 in nasopharyngeal carcinoma. Cancer Lett 326: 155-160.
40. Jain SK, Croad JL, Velusamy T, Rains JL, Bull R (2010) Chromium dinicocysteinate supplementation can lower blood glucose, CRP, MCP-1, ICAM-1, creatinine, apparently mediated by elevated blood vitamin C and adiponectin and inhibition of NFkappaB, Akt, and Glut-2 in livers of zucker diabetic fatty rats. Molecular nutrition & food research 54: 1371-1380.
41. Shih J-Y, Yuan A, Chen JJ-W, Yang P-C (2006) Tumor-Associated Macrophage: Its Role in Cancer Invasion and Metastasis. J Cancer Mol 2: 101-106.
42. Ueno T, Toi M, Saji H, Muta M, Bando H, et al. (2000) Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer. Clinical Cancer Research 6: 3282- 3289.