Tie2 signaling cooperates with TNF to promote the pro-inflammatory activation of human macrophages independently of macrophage functional phenotype

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  García, Samuel ^a   Krausz, Sarah ^a   Ambarus, Carmen A ^a   Fernández, Beatriz Malvar ^a   Hartkamp, Linda M ^a   Van Es, Inge E ^a   Hamann, Jörg ^a   Baeten, Dominique L ^a   Tak, Paul P ^a,b,c   Reedquist, Kris A ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b GLAXOSMITHKLINE   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN 2; ANGIOPOIETIN RECEPTOR; CXCL3 CHEMOKINE; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 6; INTERLEUKIN 8; JANUS KINASE; STAT PROTEIN; TUMOR NECROSIS FACTOR;

ARTICLE; CELL ACTIVATION; CELL DIFFERENTIATION; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; ENZYME REGULATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INFLAMMATION; MACROPHAGE; PHENOTYPE; POLARIZATION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ANGIOPOIETIN-1; ANGIOPOIETIN-2; CYTOKINES; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; JANUS KINASES; MACROPHAGE ACTIVATION; MACROPHAGES; MONOCYTES; PHENOTYPE; RECEPTOR, TIE-2; SIGNAL TRANSDUCTION; STAT TRANSCRIPTION FACTORS; TUMOR NECROSIS FACTOR-ALPHA; TUMOR NECROSIS FACTORS;

EID: 84896745708     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0082088     Document Type: Article

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