Acyl-CoA binding protein and epidermal barrier function

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1841, Issue 3, 2014, Pages 369-376

  Bloksgaard, Maria ^a   Neess, Ditte ^a   Færgeman, Nils J ^a   Mandrup, Susanne ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

Acyl CoA binding protein; Ceramide; Epidermal barrier; Monoalkyl diacyl glycerol; Stratum corneum; Very long chain fatty acids

Indexed keywords

DIAZEPAM BINDING INHIBITOR;

CAENORHABDITIS ELEGANS; CELL CULTURE; EPIDERMIS; GENETIC CONSERVATION; HUMAN; NONHUMAN; PERMEABILITY BARRIER; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SKIN WATER LOSS; STRATUM CORNEUM; TISSUE DISTRIBUTION;

EUKARYOTA; MAMMALIA; MUS;

ACYL-COA BINDING PROTEIN; CERAMIDE; EPIDERMAL BARRIER; MONOALKYL-DIACYL-GLYCEROL; STRATUM CORNEUM; VERY LONG CHAIN FATTY ACIDS;

ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; DIAZEPAM BINDING INHIBITOR; EPIDERMIS; GENE DELETION; GENE EXPRESSION REGULATION; HUMANS; LIPID METABOLISM; MICE; WATER-ELECTROLYTE BALANCE;

EID: 84896739281     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2013.09.013     Document Type: Review

References (101)

1. A. Guidotti, C.M. Forchetti, M.G. Corda, D. Konkel, C.D. Bennett, and E. Costa Isolation, characterization, and purification to homogeneity of an endogenous polypeptide with agonistic action on benzodiazepine receptors Proc. Natl. Acad. Sci. U. S. A. 80 1983 3531 3535 (Pubitemid 13060198)
2. I.B. Mogensen, H. Schulenberg, H.O. Hansen, F. Spener, and J. Knudsen A novel acyl-CoA-binding protein from bovine liver. Effect on fatty acid synthesis Biochem. J. 241 1987 189 192 (Pubitemid 17004729)
3. M. Burton, T.M. Rose, N.J. Faergeman, and J. Knudsen Evolution of the acyl-CoA binding protein (ACBP) Biochem. J. 392 2005 299 307 (Pubitemid 41796518)
4. N.J. Faergeman, M. Wadum, S. Feddersen, M. Burton, B.B. Kragelund, and J. Knudsen Acyl-CoA binding proteins; structural and functional conservation over 2000 MYA Mol. Cell. Biochem. 299 2007 55 65 (Pubitemid 46767538)
5. B.B. Kragelund, J. Knudsen, and F.M. Poulsen Acyl-coenzyme A binding protein (ACBP) Biochim. Biophys. Acta 1441 1999 150 161 (Pubitemid 29537735)
6. I.C. Elle Functional characterisation of six acyl-CoA binding proteins in Caenorhabditis elegans (Midterm thesis) 2009 University of Southern Denmark
7. J. Rosendal, P. Ertbjerg, and J. Knudsen Characterization of ligand binding to acyl-CoA-binding protein Biochem. J. 290 Pt 2 1993 321 326 (Pubitemid 23094922)
8. A. Frolov, and F. Schroeder Acyl coenzyme A binding protein. Conformational sensitivity to long chain fatty acyl-CoA J. Biol. Chem. 273 1998 11049 11055 (Pubitemid 28204949)
9. N.J. Faergeman, B.W. Sigurskjold, B.B. Kragelund, K.V. Andersen, and J. Knudsen Thermodynamics of ligand binding to acyl-coenzyme A binding protein studied by titration calorimetry Biochemistry 35 1996 14118 14126 (Pubitemid 26384407)
10. J. Mikkelsen, and J. Knudsen Acyl-CoA-binding protein from cow. Binding characteristics and cellular and tissue distribution Biochem. J. 248 1987 709 714
11. A. Cohen Simonsen, U. Bernchou Jensen, N. Faergeman, J. Knudsen, and O. Mouritsen Acyl-coenzyme A organizes laterally in membranes and is recognized specifically by acyl-coenzyme A binding protein FEBS Lett. 552 2003 253 258 (Pubitemid 37186869)
12. L. Kannan, J. Knudsen, and C.A. Jolly Aging and acyl-CoA binding protein alter mitochondrial glycerol-3-phosphate acyltransferase activity Biochim. Biophys. Acta 1631 2003 12 16 (Pubitemid 36165098)
13. H. Fyrst, J. Knudsen, M.A. Schott, B.H. Lubin, and F.A. Kuypers Detection of acyl-CoA-binding protein in human red blood cells and investigation of its role in membrane phospholipid renewal Biochem. J. 306 Pt 3 1995 793 799
14. H. Chao, G.G. Martin, W.K. Russell, S.D. Waghela, D.H. Russell, F. Schroeder, and A.B. Kier Membrane charge and curvature determine interaction with acyl-CoA binding protein (ACBP) and fatty acyl-CoA targeting Biochemistry 41 2002 10540 10553
15. J.T. Rasmussen, N.J. Faergeman, K. Kristiansen, and J. Knudsen Acyl-CoA-binding protein (ACBP) can mediate intermembrane acyl-CoA transport and donate acyl-CoA for beta-oxidation and glycerolipid synthesis Biochem. J. 299 Pt 1 1994 165 170 (Pubitemid 24106304)
16. H. Chao, M. Zhou, A. McIntosh, F. Schroeder, and A.B. Kier ACBP and cholesterol differentially alter fatty acyl CoA utilization by microsomal ACAT J. Lipid Res. 44 2003 72 83 (Pubitemid 36114772)
17. J.T. Rasmussen, J. Rosendal, and J. Knudsen Interaction of acyl-CoA binding protein (ACBP) on processes for which acyl-CoA is a substrate, product or inhibitor Biochem. J. 292 Pt 3 1993 907 913 (Pubitemid 23210228)
18. G.P. Owens, A.K. Sinha, J.M. Sikela, and W.E. Hahn Sequence and expression of the murine diazepam binding inhibitor Brain Res. Mol. Brain Res. 6 1989 101 108 (Pubitemid 19270010)
19. M. Shoyab, L.E. Gentry, H. Marquardt, and G.J. Todaro Isolation and characterization of a putative endogenous benzodiazepineoid (endozepine) from bovine and human brain J. Biol. Chem. 261 1986 11968 11973 (Pubitemid 17202750)
20. H. Alho, P. Bovolin, and E. Slobodyansky Diazepam binding inhibitor (DBI) processing: immunohistochemical studies in the rat brain Neurochem. Res. 15 1990 209 216 (Pubitemid 20102162)
21. D. Neess, P. Kiilerich, M.B. Sandberg, T. Helledie, R. Nielsen, and S. Mandrup ACBP - a PPAR and SREBP modulated housekeeping gene Mol. Cell. Biochem. 284 2006 149 157 (Pubitemid 44404422)
22. M. Garnier, N. Boujrad, B.O. Oke, A.S. Brown, J. Riond, P. Ferrara, M. Shoyab, C.A. Suarez-Quian, and V. Papadopoulos Diazepam binding inhibitor is a paracrine/autocrine regulator of Leydig cell proliferation and steroidogenesis: action via peripheral-type benzodiazepine receptor and independent mechanisms Endocrinology 132 1993 444 458 (Pubitemid 23019536)
23. B.A. Jackson, J.L. Braun-Werness, E. Kusano, and T.P. Dousa Concentrating defect in the adrenalectomized rat. Abnormal vasopressin-sensitive cyclic adenosine monophosphate metabolism in the papillary collecting duct J. Clin. Invest. 72 1983 997 1004 (Pubitemid 14212617)
24. S. Langaa, M. Bloksgaard, S. Bek, D. Neess, R. Norregaard, P.B. Hansen, A.B. Marcher, J. Frokiaer, S. Mandrup, and B.L. Jensen Mice with targeted disruption of the acyl-CoA binding protein display attenuated urine concentrating ability and diminished renal aquaporin-3 abundance Am. J. Physiol. Renal Physiol. 302 2012 F1034 F1044
25. H. Yanase, H. Shimizu, T. Kanda, H. Fujii, and T. Iwanaga Cellular localization of the diazepam binding inhibitor (DBI) in the gastrointestinal tract of mice and its coexistence with the fatty acid binding protein (FABP) Arch. Histol. Cytol. 64 2001 449 460 (Pubitemid 33111320)
26. J.V. Swinnen, I. Vercaeren, M. Esquenet, W. Heyns, and G. Verhoeven Androgen regulation of the messenger RNA encoding diazepam-binding inhibitor/acyl-CoA-binding protein in the rat 118 1996 65 70
27. B.M. Cavagnari, N. Sterin-Speziale, J.M. Affanni, J. Knudsen, and J.A. Santome Acyl-CoA-binding protein in the armadillo Harderian gland: its primary structure and possible role in lipid secretion Biochim. Biophys. Acta 1545 2001 314 325 (Pubitemid 32124831)
28. H. Alho, A. Vaalasti, I. Podkletnova, and L. Rechardt Expression of diazepam-binding inhibitor peptide in human skin: an immunohistochemical and ultrastructural study J. Invest. Dermatol. 101 1993 800 803 (Pubitemid 23357488)
29. T. Helledie, M. Antonius, R.V. Sorensen, A.V. Hertzel, D.A. Bernlohr, S. Kolvraa, K. Kristiansen, and S. Mandrup Lipid-binding proteins modulate ligand-dependent trans-activation by peroxisome proliferator-activated receptors and localize to the nucleus as well as the cytoplasm J. Lipid Res. 41 2000 1740 1751
30. M. Elholm, A. Garras, S. Neve, D. Tornehave, T.B. Lund, J. Skorve, T. Flatmark, K. Kristiansen, and R.K. Berge Long-chain acyl-CoA esters and acyl-CoA binding protein are present in the nucleus of rat liver cells J. Lipid Res. 41 2000 538 545 (Pubitemid 30220657)
31. J.S. Hansen, N.J. Faergeman, B.B. Kragelund, and J. Knudsen Acyl-CoA-binding protein (ACBP) localizes to the endoplasmic reticulum and Golgi in a ligand-dependent manner in mammalian cells Biochem. J. 410 2008 463 472 (Pubitemid 351429017)
32. S. Mandrup, R. Hummel, S. Ravn, G. Jensen, P.H. Andreasen, N. Gregersen, J. Knudsen, and K. Kristiansen Acyl-CoA-binding protein/diazepam-binding inhibitor gene and pseudogenes. A typical housekeeping gene family J. Mol. Biol. 228 1992 1011 1022 (Pubitemid 23017294)
33. M.B. Sandberg, M. Bloksgaard, D. Duran-Sandoval, C. Duval, B. Staels, and S. Mandrup The gene encoding acyl-CoA-binding protein is subject to metabolic regulation by both sterol regulatory element-binding protein and peroxisome proliferator-activated receptor alpha in hepatocytes J. Biol. Chem. 280 2005 5258 5266 (Pubitemid 40279998)
34. J.V. Swinnen, P. Alen, W. Heyns, and G. Verhoeven Identification of diazepam-binding inhibitor/acyl-CoA-binding protein as a sterol regulatory element-binding protein-responsive gene J. Biol. Chem. 273 1998 19938 19944 (Pubitemid 28377541)
35. T. Helledie, L. Grontved, S.S. Jensen, P. Kiilerich, L. Rietveld, T. Albrektsen, M.S. Boysen, J. Nohr, L.K. Larsen, J. Fleckner, H.G. Stunnenberg, K. Kristiansen, and S. Mandrup The gene encoding the Acyl-CoA-binding protein is activated by peroxisome proliferator-activated receptor gamma through an intronic response element functionally conserved between humans and rodents J. Biol. Chem. 277 2002 26821 26830 (Pubitemid 34951688)
36. H.O. Hansen, P.H. Andreasen, S. Mandrup, K. Kristiansen, and J. Knudsen Induction of acyl-CoA-binding protein and its mRNA in 3 T3-L1 cells by insulin during preadipocyte-to-adipocyte differentiation Biochem. J. 277 Pt 2 1991 341 344
37. J. Bhuiyan, P.H. Pritchard, S.V. Pande, and D.W. Seccombe Effects of high-fat diet and fasting on levels of acyl-coenzyme A binding protein in liver, kidney, and heart of rat Metabolism 44 1995 1185 1189 (Pubitemid 26084040)
38. J. Swinnen, I. Vercaeren, M. Esquenet, W. Heyns, and G. Verhoeven Androgen regulation of the messenger RNA encoding diazepam-binding inhibitor/acyl-CoA-binding protein in the rat Mol. Cell. Endocrinol. 118 1996 65 70 (Pubitemid 26146077)
39. M. Schmuth, Y.J. Jiang, S. Dubrac, P.M. Elias, and K.R. Feingold Thematic review series: skin lipids. Peroxisome proliferator-activated receptors and liver X receptors in epidermal biology J. Lipid Res. 49 2008 499 509
40. I.R. Harris, A.M. Farrell, W.M. Holleran, S. Jackson, C. Grunfeld, P.M. Elias, and K.R. Feingold Parallel regulation of sterol regulatory element binding protein-2 and the enzymes of cholesterol and fatty acid synthesis but not ceramide synthesis in cultured human keratinocytes and murine epidermis J. Lipid Res. 39 1998 412 422 (Pubitemid 28100678)
41. I.R. Harris, A.M. Farrell, C. Grunfeld, W.M. Holleran, P.M. Elias, and K.R. Feingold Permeability barrier disruption coordinately regulates mRNA levels for key enzymes of cholesterol, fatty acid, and ceramide synthesis in the epidermis J. Invest. Dermatol. 109 1997 783 787 (Pubitemid 28053529)
42. C.K. Schjerling, R. Hummel, J.K. Hansen, C. Borsting, J.M. Mikkelsen, K. Kristiansen, and J. Knudsen Disruption of the gene encoding the acyl-CoA-binding protein (ACB1) perturbs acyl-CoA metabolism in Saccharomyces cerevisiae J. Biol. Chem. 271 1996 22514 22521 (Pubitemid 26304689)
43. B. Gaigg, T.B.F. Neergaard, R. Schneiter, J.K. Hansen, N.J. Fargeman, N.A. Jensen, J.R. Andersen, J. Friis, R. Sandhoff, H.D. Schroder, and J. Knudsen Depletion of acyl-coenzyme A-binding protein affects sphingolipid synthesis and causes vesicle accumulation and membrane defects in Saccharomyces cerevisiae Mol. Biol. Cell 12 2001 1147 1160 (Pubitemid 33052005)
44. N.J. Faergeman, S. Feddersen, J.K. Christiansen, M.K. Larsen, R. Schneiter, C. Ungermann, K. Mutenda, P. Roepstorff, and J. Knudsen Acyl-CoA-binding protein, Acb1p, is required for normal vacuole function and ceramide synthesis in Saccharomyces cerevisiae Biochem. J. 380 2004 907 918 (Pubitemid 38850534)
45. S. Feddersen, T.B. Neergaard, J. Knudsen, and N.J. Faergeman Transcriptional regulation of phospholipid biosynthesis is linked to fatty acid metabolism by an acyl-CoA-binding-protein-dependent mechanism in Saccharomyces cerevisiae Biochem. J. 407 2007 219 230 (Pubitemid 47556987)
46. B.B. Kragelund, K. Poulsen, K.V. Andersen, T. Baldursson, J.B. Kroll, T.B. Neergard, J. Jepsen, P. Roepstorff, K. Kristiansen, F.M. Poulsen, and J. Knudsen Conserved residues and their role in the structure, function, and stability of acyl-coenzyme A binding protein Biochemistry 38 1999 2386 2394
47. I.C. Elle, K.T. Simonsen, L.C. Olsen, P.K. Birck, S. Ehmsen, S. Tuck, T.T. Le, and N.J. Faergeman Tissue- and paralogue-specific functions of acyl-CoA-binding proteins in lipid metabolism in Caenorhabditis elegans Biochem. J. 437 2011 231 241
48. H.Y. Li, and M.L. Chye Arabidopsis Acyl-CoA-binding protein ACBP2 interacts with an ethylene-responsive element-binding protein, AtEBP, via its ankyrin repeats Plant Mol. Biol. 54 2004 233 243
49. M.K. Larsen, S. Tuck, N.J. Faergeman, and J. Knudsen MAA-1, a novel acyl-CoA-binding protein involved in endosomal vesicle transport in Caenorhabditis elegans Mol. Biol. Cell 17 2006 4318 4329 (Pubitemid 44522051)
50. N.J. Faergeman, and J. Knudsen Acyl-CoA binding protein is an essential protein in mammalian cell lines Biochem. J. 368 2002 679 682 (Pubitemid 36042669)
51. S. Mandrup, R.V. Sorensen, T. Helledie, J. Nohr, T. Baldursson, C. Gram, J. Knudsen, and K. Kristiansen Inhibition of 3 T3-L1 adipocyte differentiation by expression of acyl-CoA-binding protein antisense RNA J. Biol. Chem. 273 1998 23897 23903 (Pubitemid 28435727)
52. A.D. Petrescu, H.R. Payne, A. Boedecker, H. Chao, R. Hertz, J. Bar-Tana, F. Schroeder, and A.B. Kier Physical and functional interaction of acyl-CoA-binding protein with hepatocyte nuclear factor-4{alpha} J. Biol. Chem. 278 2003 51813 51824 (Pubitemid 38020428)
53. N. Shulga, and J. Pastorino Acyl coenzyme A-binding protein augments bid-induced mitochondrial damage and cell death by activating mu-calpain J. Biol. Chem. 281 2006 30824 30833 (Pubitemid 44582137)
54. W. Loomis, M. Behrens, M. Williams, and C. Anjard Pregnenolone sulfate and cortisol induce secretion of acyl-CoA-binding protein and its conversion into endozepines from astrocytes J. Biol. Chem. 285 2010 21359 21365
55. A. Guidotti Role of DBI in brain and its posttranslational processing products in normal and abnormal behavior Neuropharmacology 30 1991 1425 1433
56. M. Katsura, Y. Mohri, K. Shuto, A. Tsujimura, M. Ukai, and S. Ohkuma Psychological stress, but not physical stress, causes increase in diazepam binding inhibitor (DBI) mRNA expression in mouse brains Brain Res. Mol. Brain Res. 104 2002 103 109 (Pubitemid 34765551)
57. M. Katsura, S. Ohkuma, A. Tsujimura, J. Xu, Y. Hibino, E. Ishikawa, and K. Kuriyama Functional involvement of benzodiazepine receptors in ethanol-induced increases of diazepam binding inhibitor (DBI) and its mRNA in the mouse brain Brain Res. Mol. Brain Res. 54 1998 124 132 (Pubitemid 28119168)
58. P. Borboni, L. Condorelli, P. De Stefanis, G. Sesti, and R. Lauro Modulation of insulin secretion by diazepam binding inhibitor and its processing products Neuropharmacology 30 1991 1399 1403
59. P. De Stefanis, F. Impagnatiello, A. Berkovich, and A. Guidotti Inhibitory effect of ODN, a naturally occurring processing product of diazepam binding inhibitor, on secretagogues-induced insulin secretion Regul. Pept. 56 1995 153 165
60. C.G. Ostenson, B. Ahren, S. Karlsson, J. Knudsen, and S. Efendic Inhibition by rat diazepam-binding inhibitor/acyl-CoA-binding protein of glucose-induced insulin secretion in the rat Eur. J. Endocrinol. 131 1994 201 204 (Pubitemid 24265355)
61. Y. Li, Y. Hao, and C. Owyang Diazepam-binding inhibitor mediates feedback regulation of pancreatic secretion and postprandial release of cholecystokinin J. Clin. Invest. 105 2000 351 359 (Pubitemid 30094455)
62. S. Oikari, T. Ahtialansaari, M.V. Heinonen, T. Mauriala, S. Auriola, K. Kiehne, U.R. Folsch, J. Janne, L. Alhonen, and K.H. Herzig Downregulation of PPARs and SREBP by acyl-CoA-binding protein overexpression in transgenic rats Pflugers Arch. 456 2008 369 377
63. H. Huang, B. Atshaves, A. Frolov, A. Kier, and F. Schroeder Acyl-coenzyme A binding protein expression alters liver fatty acyl-coenzyme A metabolism Biochemistry 44 2005 10282 10297 (Pubitemid 41076823)
64. S. Oikari, T. Ahtialansaari, A. Huotari, K. Kiehne, U.R. Folsch, S. Wolffram, J. Janne, L. Alhonen, and K.H. Herzig Effect of medium- and long-chain fatty acid diets on PPAR and SREBP-1 expression and glucose homeostasis in ACBP-overexpressing transgenic rats Acta Physiol. (Oxf.) 194 2008 57 65
65. L. Lee, C.A. DeBono, D.R. Campagna, D.C. Young, D.B. Moody, and M.D. Fleming Loss of the acyl-CoA binding protein (Acbp) results in fatty acid metabolism abnormalities in mouse hair and skin J. Invest. Dermatol. 127 2006 16 23 (Pubitemid 46005656)
66. R.S. Ohgami, D.R. Campagna, E.L. Greer, B. Antiochos, A. McDonald, J. Chen, J.J. Sharp, Y. Fujiwara, J.E. Barker, and M.D. Fleming Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells Nat. Genet. 37 2005 1264 1269 (Pubitemid 41568711)
67. R.S. Ohgami, D.R. Campagna, B. Antiochos, E.B. Wood, J.J. Sharp, J.E. Barker, and M.D. Fleming nm1054: a spontaneous, recessive, hypochromic, microcytic anemia mutation in the mouse Blood 106 2005 3625 3631 (Pubitemid 41609203)
68. C.A. Christian, A.G. Herbert, R.L. Holt, K. Peng, K.D. Sherwood, S. Pangratz-Fuehrer, U. Rudolph, and J.R. Huguenard Endogenous positive allosteric modulation of gaba receptors by diazepam binding inhibitor Neuron 78 6 2013 1063 1074
69. D. Neess, M. Bloksgaard, S. Bek, A.B. Marcher, I.C. Elle, T. Helledie, M. Due, V. Pagmantidis, B. Finsen, J. Wilbertz, M. Kruhoffer, N. Faergeman, and S. Mandrup Disruption of the acyl-CoA-binding protein gene delays hepatic adaptation to metabolic changes at weaning J. Biol. Chem. 286 2011 3460 3472
70. M. Bloksgaard, S. Bek, A.B. Marcher, D. Neess, J. Brewer, H.K. Hannibal-Bach, T. Helledie, C. Fenger, M. Due, Z. Berzina, R. Neubert, J. Chemnitz, B. Finsen, A. Clemmensen, J. Wilbertz, H. Saxtorph, J. Knudsen, L. Bagatolli, and S. Mandrup The acyl-CoA binding protein is required for normal epidermal barrier function in mice J. Lipid Res. 53 2012 2162 2174
71. D. Landrock, B.P. Atshaves, A.L. McIntosh, K.K. Landrock, F. Schroeder, and A.B. Kier Acyl-CoA binding protein gene ablation induces pre-implantation embryonic lethality in mice Lipids 45 2010 567 580
72. L.A. Bagatolli To see or not to see: lateral organization of biological membranes and fluorescence microscopy Biochim. Biophys. Acta 1758 2006 1541 1556 (Pubitemid 44466696)
73. T. Parasassi, E.K. Krasnowska, L. Bagatolli, and E. Gratton Laurdan and prodan as polarity-sensitive fluorescent membrane probes J. Fluoresc. 8 1998 362 373
74. M. Bloksgaard, J. Brewer, and L.A. Bagatolli Structural and dynamical aspects of skin studied by multiphoton excitation fluorescence microscopy-based methods Eur. J. Pharm. Sci. 2013 Apr 19. http://dx.doi.org/10.1016/j.ejps.2013. 04.010. [Epub ahead of print]
75. I. Plasencia, L. Norlen, and L.A. Bagatolli Direct visualization of lipid domains in human skin stratum corneum's lipid membranes: effect of pH and temperature Biophys. J. 93 2007 3142 3155 (Pubitemid 350097105)
76. L. Norlen, I.P. Gil, A. Simonsen, and P. Descouts Human stratum corneum lipid organization as observed by atomic force microscopy on Langmuir-Blodgett films J. Struct. Biol. 158 2007 386 400 (Pubitemid 46764566)
77. L. Norlen, I. Nicander, A. Lundsjo, T. Cronholm, and B. Forslind A new HPLC-based method for the quantitative analysis of inner stratum corneum lipids with special reference to the free fatty acid fraction Arch. Dermatol. Res. 290 1998 508 516 (Pubitemid 28468395)
78. P.W. Wertz, D.C. Swartzendruber, K.C. Madison, and D.T. Downing Composition and morphology of epidermal cyst lipids J. Invest. Dermatol. 89 1987 419 425 (Pubitemid 17158512)
79. M. Mao-Qiang, K.R. Feingold, M. Jain, and P.M. Elias Extracellular processing of phospholipids is required for permeability barrier homeostasis J. Lipid Res. 36 1995 1925 1935
80. J.W. Fluhr, J. Kao, M. Jain, S.K. Ahn, K.R. Feingold, and P.M. Elias Generation of free fatty acids from phospholipids regulates stratum corneum acidification and integrity J. Invest. Dermatol. 117 2001 44 51 (Pubitemid 32652438)
81. T. Mauro, W.M. Holleran, S. Grayson, W.N. Gao, M.Q. Man, E. Kriehuber, M. Behne, K.R. Feingold, and P.M. Elias Barrier recovery is impeded at neutral pH, independent of ionic effects: implications for extracellular lipid processing Arch. Dermatol. Res. 290 1998 215 222 (Pubitemid 28230774)
82. A.J. Thody, and S. Shuster Control and function of sebaceous glands Physiol. Rev. 69 1989 383 416 (Pubitemid 19101665)
83. H. Oku, J. Shudo, K. Mimura, A. Haratake, J. Nagata, and I. Chinen 1-O-alkyl-2,3-diacylglycerols in the skin surface lipids of the hairless mouse Lipids 30 1995 169 172
84. V. Vasireddy, Y. Uchida, N. Salem Jr., S.Y. Kim, M.N. Mandal, G.B. Reddy, R. Bodepudi, N.L. Alderson, J.C. Brown, H. Hama, A. Dlugosz, P.M. Elias, W.M. Holleran, and R. Ayyagari Loss of functional ELOVL4 depletes very long-chain fatty acids (> or = C28) and the unique omega-O-acylceramides in skin leading to neonatal death Hum. Mol. Genet. 16 2007 471 482 (Pubitemid 46522611)
85. W. Li, R. Sandhoff, M. Kono, P. Zerfas, V. Hoffmann, B.C. Ding, R.L. Proia, and C.X. Deng Depletion of ceramides with very long chain fatty acids causes defective skin permeability barrier function, and neonatal lethality in ELOVL4 deficient mice Int. J. Biol. Sci. 3 2007 120 128 (Pubitemid 46232773)
86. D.J. Cameron, Z. Tong, Z. Yang, J. Kaminoh, S. Kamiyah, H. Chen, J. Zeng, Y. Chen, L. Luo, and K. Zhang Essential role of Elovl4 in very long chain fatty acid synthesis, skin permeability barrier function, and neonatal survival Int. J. Biol. Sci. 3 2007 111 119 (Pubitemid 46238637)
87. T. Herrmann, F. van der Hoeven, H.J. Grone, A.F. Stewart, L. Langbein, I. Kaiser, G. Liebisch, I. Gosch, F. Buchkremer, W. Drobnik, G. Schmitz, and W. Stremmel Mice with targeted disruption of the fatty acid transport protein 4 (Fatp 4, Slc27a4) gene show features of lethal restrictive dermopathy J. Cell Biol. 161 2003 1105 1115 (Pubitemid 36870172)
88. M. Miyazaki, A. Dobrzyn, P.M. Elias, and J.M. Ntambi Stearoyl-CoA desaturase-2 gene expression is required for lipid synthesis during early skin and liver development Proc. Natl. Acad. Sci. U. S. A. 102 2005 12501 12506 (Pubitemid 41266388)
89. R. Westerberg, P. Tvrdik, A.B. Unden, J.E. Mansson, L. Norlen, A. Jakobsson, W.H. Holleran, P.M. Elias, A. Asadi, P. Flodby, R. Toftgard, M.R. Capecchi, and A. Jacobsson Role for ELOVL3 and fatty acid chain length in development of hair and skin function J. Biol. Chem. 279 2004 5621 5629 (Pubitemid 38220589)
90. M. Miyazaki, W.C. Man, and J.M. Ntambi Targeted disruption of stearoyl-CoA desaturase1 gene in mice causes atrophy of sebaceous and meibomian glands and depletion of wax esters in the eyelid J. Nutr. 131 2001 2260 2268 (Pubitemid 32851866)
91. E. Binczek, B. Jenke, B. Holz, R.H. Günter, M. Thevis, and W. Stoffel Obesity resistance of the stearoyl-CoA desaturase-deficient (scd1-/-) mouse results from disruption of the epidermal lipid barrier and adaptive thermoregulation Biol. Chem. 388 2007 405 418 (Pubitemid 46514691)
92. A.E. Leonard, S.L. Pereira, H. Sprecher, and Y.S. Huang Elongation of long-chain fatty acids Prog. Lipid Res. 43 2004 36 54 (Pubitemid 37433866)
93. H. Sampath, and J.M. Ntambi The role of fatty acid desaturases in epidermal metabolism Dermato-endocrinology 3 2011 62 64
94. S. Parimoo, Y. Zheng, K. Eilertsen, L. Ge, S. Prouty, J. Sundberg, and K. Stenn Identification of a novel SCD gene and expression of the SCD gene family in mouse skin J. Investig. Dermatol. Symp. Proc. 4 1999 320 322 (Pubitemid 30085829)
95. Y. Zheng, S.M. Prouty, A. Harmon, J.P. Sundberg, K.S. Stenn, and S. Parimoo Scd3-a novel gene of the stearoyl-CoA desaturase family with restricted expression in skin Genomics 71 2001 182 191 (Pubitemid 32165085)
96. J.P. Sundberg, D. Boggess, B.A. Sundberg, K. Eilertsen, S. Parimoo, M. Filippi, and K. Stenn Asebia-2 J (Scd1(ab2J)): a new allele and a model for scarring alopecia Am. J. Pathol. 156 2000 2067 2075 (Pubitemid 30641774)
97. Y. Zheng, K.J. Eilertsen, L. Ge, L. Zhang, J.P. Sundberg, S.M. Prouty, K.S. Stenn, and S. Parimoo Scd1 is expressed in sebaceous glands and is disrupted in the asebia mouse Nat. Genet. 23 1999 268 270 (Pubitemid 29526420)
98. P.R. Pennycuik, K.A. Raphael, R.E. Chapman, and M.H. Hardy The site of action of the asebia locus (ab) in the skin of the mouse Genet. Res. 48 1986 179 185 (Pubitemid 17010160)
99. J.M. Ntambi, M. Miyazaki, J.P. Stoehr, H. Lan, C.M. Kendziorski, B.S. Yandell, Y. Song, P. Cohen, J.M. Friedman, and A.D. Attie Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity Proc. Natl. Acad. Sci. U. S. A. 99 2002 11482 11486 (Pubitemid 34920951)
100. H. Sampath, M.T. Flowers, X. Liu, C.M. Paton, R. Sullivan, K. Chu, M. Zhao, and J.M. Ntambi Skin-specific deletion of stearoyl-CoA desaturase-1 alters skin lipid composition and protects mice from high fat diet-induced obesity J. Biol. Chem. 284 2009 19961 19973
101. J.W. Fluhr, M. Mao-Qiang, B.E. Brown, P.W. Wertz, D. Crumrine, J.P. Sundberg, K.R. Feingold, and P.M. Elias Glycerol regulates stratum corneum hydration in sebaceous gland deficient (asebia) mice J. Invest. Dermatol. 120 2003 728 737 (Pubitemid 36529070)