Generation of free fatty acids from phospholipids regulates stratum corneum acidification and integrity

Journal of Investigative Dermatology

Volumn 117, Issue 1, 2001, Pages 44-51

  Fluhr, Joachim W ^a,b   Kao, Jack ^a,b   Jain, Mahendra ^c   Ahn, Sung K ^a,b   Feingold, Kenneth R ^a,b   Elias, Peter M ^a,b  

^a SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF DELAWARE   (United States)

Author keywords

Acidification; Epidermis; Fatty acids; Free fatty acids; PH; Phospholipases; Phospholipids; Secretory phospholipases; Stratum corneum

Indexed keywords

1 HEXADECYL 3 TRIFLUOROETHYLGLYCERO 2 PHOSPHOMETHANOL; 4 BROMOPHENACYL BROMIDE; FATTY ACID; LINOLEIC ACID; PALMITIC ACID; PHOSPHOLIPASE; PHOSPHOLIPASE A2 INHIBITOR; PHOSPHOLIPID; PROTON PUMP; STEARIC ACID; UNCLASSIFIED DRUG;

ACIDIFICATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; HOMEOSTASIS; MALE; MOUSE; NONHUMAN; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN DETERMINATION; REGULATORY MECHANISM; SEBACEOUS GLAND; SKIN SURFACE; STRATUM CORNEUM; SWEAT GLAND;

EID: 0034932649     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0022-202X.2001.01399.x     Document Type: Article

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