A blood-based three-gene signature for the non-invasive detection of early human hepatocellular carcinoma

European Journal of Cancer

Volumn 50, Issue 5, 2014, Pages 928-936

  Shi, Ming ^a   Chen, Min Shan ^a   Sekar, Karthik ^b   Tan, Chee Kiat ^c   Ooi, London Lucien ^b   Hui, Kam M ^b,d,e,f  

^a SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^b DIVISION OF MEDICAL ONCOLOGY   (Singapore)

^c SINGAPORE GENERAL HOSPITAL   (Singapore)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^e INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^f DUKE NUS MEDICAL SCHOOL   (Singapore)

Author keywords

Alpha fetoprotein (AFP); Blood borne gene signature; C C chemokine receptor type 2 (CCR2); Chemokine (C X C motif) receptor 2 (CXCR2); Chronic hepatitis B (CHB); E1A Binding Protein P400 (EP400); Human hepatocellular carcinoma (HCC); Multivariate logistic regression; Peripheral blood mononuclear cells (PBMC)

Indexed keywords

ALPHA FETOPROTEIN; RNA;

ADULT; AGED; ARTICLE; CANCER STAGING; CCR2 GENE; CHRONIC HEPATITIS; CONTROLLED STUDY; CXCR2 GENE; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; DYNC1LI2 GENE; EP400 GENE; FEMALE; GENE; GENE EXPRESSION PROFILING; HEPATITIS B; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; MICROARRAY ANALYSIS; MIDDLE AGED; MULTIPLEX POLYMERASE CHAIN REACTION; NON INVASIVE PROCEDURE; NUCLEOTIDE SEQUENCE; PANCREAS CANCER; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; RAB18 GENE; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; SNX20 GENE; STOMACH CANCER; VERY ELDERLY; YOUNG ADULT;

ALPHA-FETOPROTEIN (AFP); BLOOD-BORNE GENE SIGNATURE; C-C CHEMOKINE RECEPTOR TYPE 2 (CCR2); CHEMOKINE (C-X-C MOTIF) RECEPTOR 2 (CXCR2); CHRONIC HEPATITIS B (CHB); E1A-BINDING PROTEIN P400 (EP400); HUMAN HEPATOCELLULAR CARCINOMA (HCC); MULTIVARIATE LOGISTIC REGRESSION; PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMC);

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, HEPATOCELLULAR; CLUSTER ANALYSIS; COHORT STUDIES; DNA HELICASES; DNA-BINDING PROTEINS; EARLY DIAGNOSIS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LEUKOCYTES, MONONUCLEAR; LIVER NEOPLASMS; LOGISTIC MODELS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PANCREATIC NEOPLASMS; RECEPTORS, CCR2; RECEPTORS, INTERLEUKIN-8B; SENSITIVITY AND SPECIFICITY; STOMACH NEOPLASMS; TRANSCRIPTOME; YOUNG ADULT;

EID: 84896738934     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2013.11.026     Document Type: Article

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