Cloning and identification of hepatocellular carcinoma down-regulated mitochondrial carrier protein, a novel liver-specific uncoupling protein

Journal of Biological Chemistry

Volumn 279, Issue 43, 2004, Pages 45235-45244

  Tan, Michelle G K ^a,b   Ooi, London Lucien P J ^b   Aw, Swee Eng ^a   Hui, Kam M ^a,b  

^a SINGAPORE GENERAL HOSPITAL   (Singapore)

^b DIVISION OF MEDICAL ONCOLOGY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

CLONING; GENES; IDENTIFICATION (CONTROL SYSTEMS); PROTEINS; TISSUE; TUMORS;

BIOLOGICAL FUNCTIONS; CANCEROUS TISSUE; HEPATOCELLULAR CARCINOMA (HCC); LIVER TISSUE;

DNA;

ADENOSINE TRIPHOSPHATE; CARRIER PROTEIN; COMPLEMENTARY DNA; DNA FRAGMENT; UNCOUPLING PROTEIN; UNCOUPLING PROTEIN 2;

AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; CANCER CELL; CANCER TISSUE; CELL MEMBRANE PERMEABILITY; CLONING; CONTROLLED STUDY; GENE EXPRESSION; GENE LOCUS; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; GENOME; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER; LIVER CELL CARCINOMA; MITOCHONDRIAL MEMBRANE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE;

ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BASE SEQUENCE; BLOTTING, NORTHERN; CARCINOMA, HEPATOCELLULAR; CARRIER PROTEINS; CELL LINE; CLONING, MOLECULAR; CONSERVED SEQUENCE; DNA, COMPLEMENTARY; DOWN-REGULATION; GENE LIBRARY; GENOME; HUMANS; IN SITU NICK-END LABELING; ION CHANNELS; LIVER; MEMBRANE POTENTIALS; MEMBRANE PROTEINS; MICE; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTONS; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; TISSUE DISTRIBUTION; TRANSFECTION;

EID: 7244245510     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M403683200     Document Type: Article

References (46)

1. Modica-Napolitano, J. S., and Singh, K. K. (2002) Exp. Rev. Mol. Med. http://www-ermm.cbcu.cam.ac.uk/02004453h.htm
2. Pedersen, P. L. (1978) Prog. Exp. Tumor Res. 22, 190-274
3. Capuano, F., Guerrieri, F., and Papa, S. (1997) Bioenerg. Biomembr. 29, 379-384
4. Fukuda, H., Ebara, M., Okuyama, M., Sugiura, N., Yoshikawa, M., Saisho, H., Shimizu, R., Motoji, N., Shigematsu, A., and Watayo, T. (2002) Carcinogenesis 23, 2019-2023
5. Parlo, R. A., and Coleman, P. S. (1984) J. Biol. Chem. 259, 9997-10003
6. Mitchell, P., and Moyle, J. (1965) Nature 208, 147-151
7. Alberts, B., Bray, D., Lewis, J., Raff, M., Roberts, K., and Watson, J. D. (1994) Molecular Biology of The Cells, 3rd Ed., pp. 653-684, Garland Publishing, New York
8. Heytler, P. G. (1980) Pharmacol. Ther. 10, 461-472
9. Terada, H. (1990) Environ. Health Perspect. 87, 213-218
10. Kohnke, D., Ludwig, B., and Kadenbach, B. (1993) FEBS Lett. 336, 90-94
11. Klingenberg, M. (1990) Trends Biochem. Sci. 15, 108-112
12. Stuart, J. A., Brindle, K. M., Harper, J. A., and Brand, M. D. (1999) J. Bioenerg. Biomembr. 31, 517-525
13. Summerhayes, I. C., Lampidis, T. J., Bernal, S. D., Nadakavukaren, J. J., Nadakavukaren, K. K., Shepherd, E. L., and Chen, L. B. (1982) Proc. Natl. Acad. Sci. U. S. A. 79, 5292-5296
14. Bernal, S. D., Lampidis, T. J., Summerhayes, I. C., and Chen, L. B. (1982) Science 218, 1117-1119
15. Bernal, S. D., Lampidis, T. J., McIsaac, R. M., and Chen, L. B. (1983) Science 222, 169-172
16. Lampidis, T. J., Bernal, S. D., Summerhayes, I. C., and Chen, L. B. (1983) Cancer Res. 43, 716-720
17. Nadakavukaren, K. K., Nadakavukaren, J. J., and Chen, L. B. (1985) Cancer Res. 45, 6093-6099
18. Modica-Napolitano, J. S., and Aprille, J. R. (1987) Cancer Res. 47, 4361-4365
19. Ng, A., Tang, J. P., Goh, C. H. K., and Hui, K. M. (2003) Int. J. Cancer 104, 179-187
20. Kobayashi, K., Sinasac, D. S., Iijima, M., Boright, A. P., Begum, L., Lee, J. R., Yasuda, T., Ikeda, S., Hirano, R., Terazono, H., Crackower, M. A., Kondo, I., Tsui, L. C., Scherer, S. W., and Saheki, T. (1999) Nat. Genet. 22, 159-163
21. Palmieri, F. (1994) FEBS Lett. 346, 48-54
22. Walker, J. E., and Runswick, M. J. (1993) J. Bioenerg. Biomembr. 25, 435-446
23. Kuan, J., and Saier, M. H., Jr. (1993) Crit. Rev. Biochem. Mol. Biol. 28, 209-233
24. Scorrano, L., Petronilli, V., Colonna, R., Di Lisa, F., and Bernardi, P. (1999) J. Biol. Chem. 274, 24657-24663
25. Crompton, M. (1999) Biochem. J. 341, 233-249
26. Kroemer, G., and Reed, J. C. (2000) Nat. Med. 6, 513-519
27. Pastorino, J. G., Chen, S. T., Tafani, M., Snyder, J. W., and Farber, J. L. (1998) J. Biol. Chem. 273, 7770-7775
28. Zamzami, N., and Kroemer, G. (2001) Nat. Rev. Mol. Cell Biol. 2, 67-71
29. O'Brien, S. J., Menotti-Raymond, M., Murphy, W. J., Nash, W. G., Wienberg, J., Stanyon, R., Copeland, N. G., Jenkins, N. A., Womack, J. E., and Marshall Graves, J. A. (1999) Science 286, 458-481
30. Ramsey, J. J., Harper, M. E., and Weindruch, R. (2000) Free. Radic. Biol. Med. 29, 946-968
31. Brand, M. D., Chien, L. F., Ainscow, E. K., Rolfe, D. F., and Porter, R. K. (1994) Biochim. Biophys. Acta 1187, 132-139
32. Nobes, C. D., Brown, G. C., Olive, P. N., and Brand, M. D. (1990) J. Biol. Chem. 265, 12903-12909
33. Marchetti, P., Castedo, M., Susin, S. A., Zamzami, N., Hirsch, T., Macho, A., Haeffner, A., Hirsch, F., Geuskens, M., and Kroemer, G. (1996) J. Exp. Med. 184, 1155-1160
34. Zamzami, N., and Kroemer, G. (2003) Curr. Biol. 13, R71-R73
35. Mills, E. M., Xu, D., Fergusson, M. M., Combs, C. A., Xu, Y., and Finkel, T. (2002) J. Biol. Chem. 277, 27385-27392
36. Pessayre, D., Berson, A., Fromenty, B., and Mansouri, A. (2001) Semin. Liver Dis. 21, 57-69
37. Loguercio, C., and Federico, A. (2003) Free Radic. Biol. Med. 34, 1-10
38. Jaeschke, H. (2000) J. Gastroenterol. Hepatol. 15, 718-724
39. Skulachev, V. P. (1998) Biochim. Biophys. Acta 1363, 100-124
40. Rolfe, D. F., and Brand, M. D. (1997) Biosci. Rep. 17, 9-16
41. Ricquier, D., and Bouillaud, F. (2000) Biochem. J. 345, 161-179
42. Aquila, H., Link, T. A., and Klingenberg, M. (1987) FEBS Lett. 212, 1-9
43. Davis, S., Weiss, M. J., Wong, J. R., Lampidis, T. J., and Chen, L. B. (1985) J. Biol. Chem. 260, 13844-13850
44. Modica-Napolitano, J. S., Joyal, J. L., Ara, G., Oseroff, A. R., and Aprille, J. R. (1990) Cancer Res. 50, 7876-7881
45. Modica-Napolitano, J. S., and Aprille, J. R. (2001) Adv. Drug Delivery Rev. 49, 63-70
46. Morgan, J., and Oseroff, A. R. (2001) Adv. Drug Delivery Rev. 49, 71-86