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Volumn 140, Issue 3, 2014, Pages 453-460

Clinicopathologic characteristics of ALK rearrangements in primary lung adenocarcinoma with identified EGFR and KRAS status

Author keywords

ALK; EGFR; Fluorescent in situ hybridization; KRAS; Lung adenocarcinoma

Indexed keywords

ANAPLASTIC LYMPHOMA KINASE; EPIDERMAL GROWTH FACTOR RECEPTOR; K RAS PROTEIN;

EID: 84896737901     PISSN: 01715216     EISSN: 14321335     Source Type: Journal    
DOI: 10.1007/s00432-014-1584-8     Document Type: Article
Times cited : (37)

References (27)
  • 1
    • 15744362912 scopus 로고    scopus 로고
    • The 2004 World Health Organization classification of lung tumors
    • 10.1053/j.ro.2005.01.001 15898407 10.1053/j.ro.2005.01.001
    • Beasley MB, Brambilla E, Travis WD (2005) The 2004 World Health Organization classification of lung tumors. Semin Roentgenol 40(2):90-97. doi: 10.1053/j.ro.2005.01.001
    • (2005) Semin Roentgenol , vol.40 , Issue.2 , pp. 90-97
    • Beasley, M.B.1    Brambilla, E.2    Travis, W.D.3
  • 2
    • 84864432794 scopus 로고    scopus 로고
    • Correlations between the percentage of tumor cells showing an anaplastic lymphoma kinase (ALK) gene rearrangement, ALK signal copy number, and response to crizotinib therapy in ALK fluorescence in situ hybridization-positive nonsmall cell lung cancer
    • 10.1002/cncr.27411 1:CAS:528:DC%2BC38Xht12itrbM 3342464 22282074 10.1002/cncr.27411
    • Camidge DR, Theodoro M, Maxson DA, Skokan M, O'Brien T, Lu X, Doebele RC, Baron AE, Varella-Garcia M (2012) Correlations between the percentage of tumor cells showing an anaplastic lymphoma kinase (ALK) gene rearrangement, ALK signal copy number, and response to crizotinib therapy in ALK fluorescence in situ hybridization-positive nonsmall cell lung cancer. Cancer 118(18):4486-4494. doi: 10.1002/cncr.27411
    • (2012) Cancer , vol.118 , Issue.18 , pp. 4486-4494
    • Camidge, D.R.1    Theodoro, M.2    Maxson, D.A.3    Skokan, M.4    O'Brien, T.5    Lu, X.6    Doebele, R.C.7    Baron, A.E.8    Varella-Garcia, M.9
  • 4
    • 84881256393 scopus 로고    scopus 로고
    • ALK rearrangements are mutually exclusive with mutations in EGFR or KRAS: An analysis of 1,683 patients with non-small cell lung cancer
    • 10.1158/1078-0432.CCR-13-0318 1:CAS:528:DC%2BC3sXht1amt7zI 23729361 10.1158/1078-0432.CCR-13-0318
    • Gainor JF, Varghese AM, Ou SH, Kabraji S, Awad MM, Katayama R, Pawlak A, Mino-Kenudson M, Yeap BY, Riely GJ et al (2013) ALK rearrangements are mutually exclusive with mutations in EGFR or KRAS: an analysis of 1,683 patients with non-small cell lung cancer. Clin Cancer Res 19(15):4273-4281. doi: 10.1158/1078-0432.CCR-13-0318
    • (2013) Clin Cancer Res , vol.19 , Issue.15 , pp. 4273-4281
    • Gainor, J.F.1    Varghese, A.M.2    Ou, S.H.3    Kabraji, S.4    Awad, M.M.5    Katayama, R.6    Pawlak, A.7    Mino-Kenudson, M.8    Yeap, B.Y.9    Riely, G.J.10
  • 5
    • 34548457234 scopus 로고    scopus 로고
    • The IASLC Lung Cancer Staging Project: Proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumours
    • 10.1097/JTO.0b013e31812f3c1a 17762336 10.1097/JTO.0b013e31812f3c1a
    • Goldstraw P, Crowley J, Chansky K, Giroux DJ, Groome PA, Rami-Porta R, Postmus PE, Rusch V, Sobin L (2007) The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumours. J Thorac Oncol 2(8):706-714. doi: 10.1097/JTO.0b013e31812f3c1a
    • (2007) J Thorac Oncol , vol.2 , Issue.8 , pp. 706-714
    • Goldstraw, P.1    Crowley, J.2    Chansky, K.3    Giroux, D.J.4    Groome, P.A.5    Rami-Porta, R.6    Postmus, P.E.7    Rusch, V.8    Sobin, L.9
  • 6
    • 37549060017 scopus 로고    scopus 로고
    • EML4-ALK fusion is linked to histological characteristics in a subset of lung cancers
    • 10.1097/JTO.0b013e31815e8b60 18166835 10.1097/JTO.0b013e31815e8b60
    • Inamura K, Takeuchi K, Togashi Y, Nomura K, Ninomiya H, Okui M, Satoh Y, Okumura S, Nakagawa K, Soda M et al (2008) EML4-ALK fusion is linked to histological characteristics in a subset of lung cancers. J Thorac Oncol 3(1):13-17. doi: 10.1097/JTO.0b013e31815e8b60
    • (2008) J Thorac Oncol , vol.3 , Issue.1 , pp. 13-17
    • Inamura, K.1    Takeuchi, K.2    Togashi, Y.3    Nomura, K.4    Ninomiya, H.5    Okui, M.6    Satoh, Y.7    Okumura, S.8    Nakagawa, K.9    Soda, M.10
  • 7
    • 77955635233 scopus 로고    scopus 로고
    • Cancer statistics, 2010
    • 10.3322/caac.20073 20610543 10.3322/caac.20073
    • Jemal A, Siegel R, Xu J, Ward E (2010) Cancer statistics, 2010. CA Cancer J Clin 60(5):277-300. doi: 10.3322/caac.20073
    • (2010) CA Cancer J Clin , vol.60 , Issue.5 , pp. 277-300
    • Jemal, A.1    Siegel, R.2    Xu, J.3    Ward, E.4
  • 9
    • 84868273808 scopus 로고    scopus 로고
    • IASLC/ATS/ERS international multidisciplinary classification of lung adenocarcinoma: Novel concepts and radiologic implications
    • 10.1097/RTI.0b013e3182688d62 23086014 10.1097/RTI.0b013e3182688d62
    • Lee HJ, Lee CH, Jeong YJ, Chung DH, Goo JM, Park CM, Austin JH (2012) IASLC/ATS/ERS international multidisciplinary classification of lung adenocarcinoma: novel concepts and radiologic implications. J Thorac Imaging 27(6):340-353. doi: 10.1097/RTI.0b013e3182688d62
    • (2012) J Thorac Imaging , vol.27 , Issue.6 , pp. 340-353
    • Lee, H.J.1    Lee, C.H.2    Jeong, Y.J.3    Chung, D.H.4    Goo, J.M.5    Park, C.M.6    Austin, J.H.7
  • 10
    • 84872330303 scopus 로고    scopus 로고
    • Clinical significance of EML4-ALK fusion gene and association with EGFR and KRAS gene mutations in 208 Chinese patients with non-small cell lung cancer
    • 10.1371/journal.pone.0052093 1:CAS:528:DC%2BC3sXhsVGktL4%3D 3544857 23341890 10.1371/journal.pone.0052093
    • Li Y, Li Y, Yang T, Wei S, Wang J, Wang M, Wang Y, Zhou Q, Liu H, Chen J (2013) Clinical significance of EML4-ALK fusion gene and association with EGFR and KRAS gene mutations in 208 Chinese patients with non-small cell lung cancer. PLoS ONE 8(1):e52093. doi: 10.1371/journal.pone.0052093
    • (2013) PLoS ONE , vol.8 , Issue.1 , pp. 52093
    • Li, Y.1    Li, Y.2    Yang, T.3    Wei, S.4    Wang, J.5    Wang, M.6    Wang, Y.7    Zhou, Q.8    Liu, H.9    Chen, J.10
  • 11
    • 70349510460 scopus 로고    scopus 로고
    • Exon array profiling detects EML4-ALK fusion in breast, colorectal, and non-small cell lung cancers
    • 10.1158/1541-7786.MCR-08-0522 1:CAS:528:DC%2BD1MXhtFCjtbvN 19737969 10.1158/1541-7786.MCR-08-0522
    • Lin E, Li L, Guan Y, Soriano R, Rivers CS, Mohan S, Pandita A, Tang J, Modrusan Z (2009) Exon array profiling detects EML4-ALK fusion in breast, colorectal, and non-small cell lung cancers. Mol Cancer Res 7(9):1466-1476. doi: 10.1158/1541-7786.MCR-08-0522
    • (2009) Mol Cancer Res , vol.7 , Issue.9 , pp. 1466-1476
    • Lin, E.1    Li, L.2    Guan, Y.3    Soriano, R.4    Rivers, C.S.5    Mohan, S.6    Pandita, A.7    Tang, J.8    Modrusan, Z.9
  • 12
    • 84879290901 scopus 로고    scopus 로고
    • Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: Guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology
    • 10.1016/j.jmoldx.2013.03.001 1:CAS:528:DC%2BC3sXls1SnsLk%3D 23562183 10.1016/j.jmoldx.2013.03.001
    • Lindeman NI, Cagle PT, Beasley MB, Chitale DA, Dacic S, Giaccone G, Jenkins RB, Kwiatkowski DJ, Saldivar JS, Squire J et al (2013) Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology. J Mol Diagn 15(4):415-453. doi: 10.1016/j.jmoldx.2013.03. 001
    • (2013) J Mol Diagn , vol.15 , Issue.4 , pp. 415-453
    • Lindeman, N.I.1    Cagle, P.T.2    Beasley, M.B.3    Chitale, D.A.4    Dacic, S.5    Giaccone, G.6    Jenkins, R.B.7    Kwiatkowski, D.J.8    Saldivar, J.S.9    Squire, J.10
  • 13
    • 79251490374 scopus 로고    scopus 로고
    • New driver mutations in non-small-cell lung cancer
    • 10.1016/S1470-2045(10)70087-5 1:CAS:528:DC%2BC3MXht12ns74%3D 21277552 10.1016/S1470-2045(10)70087-5
    • Pao W, Girard N (2011) New driver mutations in non-small-cell lung cancer. Lancet Oncol 12(2):175-180. doi: 10.1016/S1470-2045(10)70087-5
    • (2011) Lancet Oncol , vol.12 , Issue.2 , pp. 175-180
    • Pao, W.1    Girard, N.2
  • 14
    • 69349083935 scopus 로고    scopus 로고
    • Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population
    • 10.1158/1078-0432.CCR-09-0802 1:CAS:528:DC%2BD1MXpvFeitrY%3D 2865649 19671850 10.1158/1078-0432.CCR-09-0802
    • Rodig SJ, Mino-Kenudson M, Dacic S, Yeap BY, Shaw A, Barletta JA, Stubbs H, Law K, Lindeman N, Mark E et al (2009) Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population. Clin Cancer Res 15(16):5216-5523. doi: 10.1158/1078-0432.CCR-09-0802
    • (2009) Clin Cancer Res , vol.15 , Issue.16 , pp. 5216-5523
    • Rodig, S.J.1    Mino-Kenudson, M.2    Dacic, S.3    Yeap, B.Y.4    Shaw, A.5    Barletta, J.A.6    Stubbs, H.7    Law, K.8    Lindeman, N.9    Mark, E.10
  • 15
    • 70349336416 scopus 로고    scopus 로고
    • Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK
    • 10.1200/JCO.2009.22.6993 1:CAS:528:DC%2BD1MXht1WisbvF 19667264 10.1200/JCO.2009.22.6993
    • Shaw AT, Yeap BY, Mino-Kenudson M, Digumarthy SR, Costa DB, Heist RS, Solomon B, Stubbs H, Admane S, McDermott U et al (2009) Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK. J Clin Oncol 27(26):4247-4253. doi: 10.1200/JCO.2009.22.6993
    • (2009) J Clin Oncol , vol.27 , Issue.26 , pp. 4247-4253
    • Shaw, A.T.1    Yeap, B.Y.2    Mino-Kenudson, M.3    Digumarthy, S.R.4    Costa, D.B.5    Heist, R.S.6    Solomon, B.7    Stubbs, H.8    Admane, S.9    McDermott, U.10
  • 16
    • 34547638047 scopus 로고    scopus 로고
    • Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
    • 10.1038/nature05945 1:CAS:528:DC%2BD2sXosVSrtrs%3D 17625570 10.1038/nature05945
    • Soda M, Choi YL, Enomoto M, Takada S, Yamashita Y, Ishikawa S, Fujiwara S, Watanabe H, Kurashina K, Hatanaka H et al (2007) Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature 448(7153):561-566. doi: 10.1038/nature05945
    • (2007) Nature , vol.448 , Issue.7153 , pp. 561-566
    • Soda, M.1    Choi, Y.L.2    Enomoto, M.3    Takada, S.4    Yamashita, Y.5    Ishikawa, S.6    Fujiwara, S.7    Watanabe, H.8    Kurashina, K.9    Hatanaka, H.10
  • 18
    • 74249123333 scopus 로고    scopus 로고
    • ALK gene rearrangements: A new therapeutic target in a molecularly defined subset of non-small cell lung cancer
    • 10.1097/JTO.0b013e3181c4dedb 20009909 10.1097/JTO.0b013e3181c4dedb
    • Solomon B, Varella-Garcia M, Camidge DR (2009) ALK gene rearrangements: a new therapeutic target in a molecularly defined subset of non-small cell lung cancer. J Thorac Oncol 4(12):1450-1454. doi: 10.1097/JTO.0b013e3181c4dedb
    • (2009) J Thorac Oncol , vol.4 , Issue.12 , pp. 1450-1454
    • Solomon, B.1    Varella-Garcia, M.2    Camidge, D.R.3
  • 20
    • 84856893071 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase as a new target for the treatment of non-small-cell lung cancer
    • 10.1586/era.11.157 1:CAS:528:DC%2BC3MXhsVSiur7J 22050016 10.1586/era.11.157
    • Tiseo M, Gelsomino F, Bartolotti M, Bordi P, Bersanelli M, Rossi G, Ardizzoni A (2011) Anaplastic lymphoma kinase as a new target for the treatment of non-small-cell lung cancer. Expert Rev Anticancer Ther 11(11):1677-1687. doi: 10.1586/era.11.157
    • (2011) Expert Rev Anticancer Ther , vol.11 , Issue.11 , pp. 1677-1687
    • Tiseo, M.1    Gelsomino, F.2    Bartolotti, M.3    Bordi, P.4    Bersanelli, M.5    Rossi, G.6    Ardizzoni, A.7
  • 21
    • 33847606966 scopus 로고    scopus 로고
    • Changing trends in the distribution of the histologic types of lung cancer: A review of 4,439 cases
    • 10.1016/j.anndiagpath.2006.04.006 17349566 10.1016/j.anndiagpath.2006.04. 006
    • Wahbah M, Boroumand N, Castro C, El-Zeky F, Eltorky M (2007) Changing trends in the distribution of the histologic types of lung cancer: a review of 4,439 cases. Ann Diagn Pathol 11(2):89-96. doi: 10.1016/j.anndiagpath.2006.04. 006
    • (2007) Ann Diagn Pathol , vol.11 , Issue.2 , pp. 89-96
    • Wahbah, M.1    Boroumand, N.2    Castro, C.3    El-Zeky, F.4    Eltorky, M.5
  • 22
    • 84865845420 scopus 로고    scopus 로고
    • EML4-ALK rearrangement and its clinical significance in Chinese patients with advanced non-small cell lung cancer
    • 10.1159/000341381 1:CAS:528:DC%2BC38XhsVWmt73O 22964709 10.1159/000341381
    • Wang Z, Zhang X, Bai H, Zhao J, Zhuo M, An T, Duan J, Yang L, Wu M, Wang S et al (2012) EML4-ALK rearrangement and its clinical significance in Chinese patients with advanced non-small cell lung cancer. Oncology 83(5):248-256. doi: 10.1159/000341381
    • (2012) Oncology , vol.83 , Issue.5 , pp. 248-256
    • Wang, Z.1    Zhang, X.2    Bai, H.3    Zhao, J.4    Zhuo, M.5    An, T.6    Duan, J.7    Yang, L.8    Wu, M.9    Wang, S.10
  • 23
    • 65249095599 scopus 로고    scopus 로고
    • The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS
    • 10.1002/cncr.24181 1:CAS:528:DC%2BD1MXltVOnur4%3D 19170230 10.1002/cncr.24181
    • Wong DW, Leung EL, So KK, Tam IY, Sihoe AD, Cheng LC, Ho KK, Au JS, Chung LP, Pik Wong M (2009) The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS. Cancer 115(8):1723-1733. doi: 10.1002/cncr.24181
    • (2009) Cancer , vol.115 , Issue.8 , pp. 1723-1733
    • Wong, D.W.1    Leung, E.L.2    So, K.K.3    Tam, I.Y.4    Sihoe, A.D.5    Cheng, L.C.6    Ho, K.K.7    Au, J.S.8    Chung, L.P.9    Pik Wong, M.10
  • 24
    • 84655164310 scopus 로고    scopus 로고
    • EML4-ALK translocation predicts better outcome in lung adenocarcinoma patients with wild-type EGFR
    • 10.1097/JTO.0b013e3182370e30 1:CAS:528:DC%2BC38XjtFKjsro%3D 22124476 10.1097/JTO.0b013e3182370e30
    • Wu SG, Kuo YW, Chang YL, Shih JY, Chen YH, Tsai MF, Yu CJ, Yang CH, Yang PC (2012) EML4-ALK translocation predicts better outcome in lung adenocarcinoma patients with wild-type EGFR. J Thorac Oncol 7(1):98-104. doi: 10.1097/JTO.0b013e3182370e30
    • (2012) J Thorac Oncol , vol.7 , Issue.1 , pp. 98-104
    • Wu, S.G.1    Kuo, Y.W.2    Chang, Y.L.3    Shih, J.Y.4    Chen, Y.H.5    Tsai, M.F.6    Yu, C.J.7    Yang, C.H.8    Yang, P.C.9
  • 25
    • 84881339295 scopus 로고    scopus 로고
    • Comparison of IHC, FISH and RT-PCR methods for detection of ALK rearrangements in 312 non-small cell lung cancer patients in Taiwan
    • 10.1371/journal.pone.0070839 1:CAS:528:DC%2BC3sXhtlWgt7bL 3737393 23951022 10.1371/journal.pone.0070839
    • Wu YC, Chang IC, Wang CL, Chen TD, Chen YT, Liu HP, Chu Y, Chiu YT, Wu TH, Chou LH et al (2013) Comparison of IHC, FISH and RT-PCR methods for detection of ALK rearrangements in 312 non-small cell lung cancer patients in Taiwan. PLoS ONE 8(8):e70839. doi: 10.1371/journal.pone.0070839
    • (2013) PLoS ONE , vol.8 , Issue.8 , pp. 70839
    • Wu, Y.C.1    Chang, I.C.2    Wang, C.L.3    Chen, T.D.4    Chen, Y.T.5    Liu, H.P.6    Chu, Y.7    Chiu, Y.T.8    Wu, T.H.9    Chou, L.H.10
  • 26
    • 77954399760 scopus 로고    scopus 로고
    • Fusion of EML4 and ALK is associated with development of lung adenocarcinomas lacking EGFR and KRAS mutations and is correlated with ALK expression
    • 10.1186/1476-4598-9-188 2908583 20624322 10.1186/1476-4598-9-188
    • Zhang X, Zhang S, Yang X, Yang J, Zhou Q, Yin L, An S, Lin J, Chen S, Xie Z et al (2010) Fusion of EML4 and ALK is associated with development of lung adenocarcinomas lacking EGFR and KRAS mutations and is correlated with ALK expression. Mol Cancer 9:188. doi: 10.1186/1476-4598-9-188
    • (2010) Mol Cancer , vol.9 , pp. 188
    • Zhang, X.1    Zhang, S.2    Yang, X.3    Yang, J.4    Zhou, Q.5    Yin, L.6    An, S.7    Lin, J.8    Chen, S.9    Xie, Z.10
  • 27
    • 84878576680 scopus 로고    scopus 로고
    • Evaluation of ALK rearrangement in Chinese non-small cell lung cancer using FISH, immunohistochemistry, and real-time quantitative RT- PCR on paraffin-embedded tissues
    • 10.1371/journal.pone.0064821 1:CAS:528:DC%2BC3sXpslOnsrg%3D 3669339 23741400 10.1371/journal.pone.0064821
    • Zhang YG, Jin ML, Li L, Zhao HY, Zeng X, Jiang L, Wei P, Diao XL, Li X, Cao Q et al (2013) Evaluation of ALK rearrangement in Chinese non-small cell lung cancer using FISH, immunohistochemistry, and real-time quantitative RT- PCR on paraffin-embedded tissues. PLoS ONE 8(5):e64821. doi: 10.1371/journal.pone. 0064821
    • (2013) PLoS ONE , vol.8 , Issue.5 , pp. 64821
    • Zhang, Y.G.1    Jin, M.L.2    Li, L.3    Zhao, H.Y.4    Zeng, X.5    Jiang, L.6    Wei, P.7    Diao, X.L.8    Li, X.9    Cao, Q.10


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