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Volumn 8, Issue 8, 2013, Pages

Comparison of IHC, FISH and RT-PCR Methods for Detection of ALK Rearrangements in 312 Non-Small Cell Lung Cancer Patients in Taiwan

Author keywords

[No Author keywords available]

Indexed keywords

ANAPLASTIC LYMPHOMA KINASE; EPIDERMAL GROWTH FACTOR RECEPTOR;

EID: 84881339295     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0070839     Document Type: Article
Times cited : (99)

References (48)
  • 2
    • 41349099104 scopus 로고    scopus 로고
    • Cancer statistics, 2008
    • doi:10.3322/CA.2007.0010
    • Jemal A, Siegel R, Ward E, Hao Y, Xu J, et al. (2008) Cancer statistics, 2008. CA Cancer J Clin 58: 71-96. doi:10.3322/CA.2007.0010. PubMed: 18287387.
    • (2008) CA Cancer J Clin , vol.58 , pp. 71-96
    • Jemal, A.1    Siegel, R.2    Ward, E.3    Hao, Y.4    Xu, J.5
  • 3
    • 75249087060 scopus 로고    scopus 로고
    • Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial
    • doi:10.1016/S1470-2045(09)70364-X
    • Mitsudomi T, Morita S, Yatabe Y, Negoro S, Okamoto I, et al. (2010) Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial. Lancet Oncol 11: 121-128. doi:10.1016/S1470-2045(09)70364-X. PubMed: 20022809.
    • (2010) Lancet Oncol , vol.11 , pp. 121-128
    • Mitsudomi, T.1    Morita, S.2    Yatabe, Y.3    Negoro, S.4    Okamoto, I.5
  • 4
    • 69949162760 scopus 로고    scopus 로고
    • Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
    • doi:10.1056/NEJMoa0810699
    • Mok TS, Wu YL, Thongprasert S, Yang CH, Chu DT, et al. (2009) Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 361: 947-957. doi:10.1056/NEJMoa0810699. PubMed: 19692680.
    • (2009) N Engl J Med , vol.361 , pp. 947-957
    • Mok, T.S.1    Wu, Y.L.2    Thongprasert, S.3    Yang, C.H.4    Chu, D.T.5
  • 5
    • 77953930730 scopus 로고    scopus 로고
    • Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR
    • doi:10.1056/NEJMoa0909530
    • Maemondo M, Inoue A, Kobayashi K, Sugawara S, Oizumi S, et al. (2010) Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. N Engl J Med 362: 2380-2388. doi:10.1056/NEJMoa0909530. PubMed: 20573926.
    • (2010) N Engl J Med , vol.362 , pp. 2380-2388
    • Maemondo, M.1    Inoue, A.2    Kobayashi, K.3    Sugawara, S.4    Oizumi, S.5
  • 6
    • 80051784829 scopus 로고    scopus 로고
    • A systematic review and Canadian consensus recommendations on the use of biomarkers in the treatment of non-small cell lung cancer
    • doi:10.1097/JTO.0b013e318220cb8e
    • Ellis PM, Blais N, Soulieres D, Ionescu DN, Kashyap M, et al. (2011) A systematic review and Canadian consensus recommendations on the use of biomarkers in the treatment of non-small cell lung cancer. J Thorac Oncol 6: 1379-1391. doi:10.1097/JTO.0b013e318220cb8e. PubMed: 21709590.
    • (2011) J Thorac Oncol , vol.6 , pp. 1379-1391
    • Ellis, P.M.1    Blais, N.2    Soulieres, D.3    Ionescu, D.N.4    Kashyap, M.5
  • 7
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • doi:10.1056/NEJMoa040938
    • Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, et al. (2004) Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 350: 2129-2139. doi:10.1056/NEJMoa040938. PubMed: 15118073.
    • (2004) N Engl J Med , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3    Gurubhagavatula, S.4    Okimoto, R.A.5
  • 8
    • 34547638047 scopus 로고    scopus 로고
    • Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
    • doi:10.1038/nature05945
    • Soda M, Choi YL, Enomoto M, Takada S, Yamashita Y, et al. (2007) Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature 448: 561-566. doi:10.1038/nature05945. PubMed: 17625570.
    • (2007) Nature , vol.448 , pp. 561-566
    • Soda, M.1    Choi, Y.L.2    Enomoto, M.3    Takada, S.4    Yamashita, Y.5
  • 9
    • 37549057005 scopus 로고    scopus 로고
    • The anaplastic lymphoma kinase in the pathogenesis of cancer
    • doi:10.1038/nrc2291
    • Chiarle R, Voena C, Ambrogio C, Piva R, Inghirami G, (2008) The anaplastic lymphoma kinase in the pathogenesis of cancer. Nat Rev Cancer 8: 11-23. doi:10.1038/nrc2291. PubMed: 18097461.
    • (2008) Nat Rev Cancer , vol.8 , pp. 11-23
    • Chiarle, R.1    Voena, C.2    Ambrogio, C.3    Piva, R.4    Inghirami, G.5
  • 10
    • 66949152073 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase: signalling in development and disease
    • doi:10.1042/BJ20090387
    • Palmer RH, Vernersson E, Grabbe C, Hallberg B, (2009) Anaplastic lymphoma kinase: signalling in development and disease. Biochem J 420: 345-361. doi:10.1042/BJ20090387. PubMed: 19459784.
    • (2009) Biochem J , vol.420 , pp. 345-361
    • Palmer, R.H.1    Vernersson, E.2    Grabbe, C.3    Hallberg, B.4
  • 11
    • 0031755958 scopus 로고    scopus 로고
    • Nucleophosmin-anaplastic lymphoma kinase of large-cell anaplastic lymphoma is a constitutively active tyrosine kinase that utilizes phospholipase C-gamma to mediate its mitogenicity
    • 9819383
    • Bai RY, Dieter P, Peschel C, Morris SW, Duyster J, (1998) Nucleophosmin-anaplastic lymphoma kinase of large-cell anaplastic lymphoma is a constitutively active tyrosine kinase that utilizes phospholipase C-gamma to mediate its mitogenicity. Mol Cell Biol 18: 6951-6961. PubMed: 9819383.
    • (1998) Mol Cell Biol , vol.18 , pp. 6951-6961
    • Bai, R.Y.1    Dieter, P.2    Peschel, C.3    Morris, S.W.4    Duyster, J.5
  • 12
    • 0037372285 scopus 로고    scopus 로고
    • NPM-ALK transgenic mice spontaneously develop T-cell lymphomas and plasma cell tumors
    • doi:10.1182/blood-2002-05-1343
    • Chiarle R, Gong JZ, Guasparri I, Pesci A, Cai J, et al. (2003) NPM-ALK transgenic mice spontaneously develop T-cell lymphomas and plasma cell tumors. Blood 101: 1919-1927. doi:10.1182/blood-2002-05-1343. PubMed: 12424201.
    • (2003) Blood , vol.101 , pp. 1919-1927
    • Chiarle, R.1    Gong, J.Z.2    Guasparri, I.3    Pesci, A.4    Cai, J.5
  • 13
    • 79961088497 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase in human cancer
    • doi:10.1530/JME-11-0004
    • Barreca A, Lasorsa E, Riera L, Machiorlatti R, Piva R, et al. (2011) Anaplastic lymphoma kinase in human cancer. J Mol Endocrinol 47: R11-R23. doi:10.1530/JME-11-0004. PubMed: 21502284.
    • (2011) J Mol Endocrinol , vol.47
    • Barreca, A.1    Lasorsa, E.2    Riera, L.3    Machiorlatti, R.4    Piva, R.5
  • 14
    • 48549098388 scopus 로고    scopus 로고
    • Identification of novel isoforms of the EML4-ALK transforming gene in non-small cell lung cancer
    • doi:10.1158/0008-5472.CAN-07-6158
    • Choi YL, Takeuchi K, Soda M, Inamura K, Togashi Y, et al. (2008) Identification of novel isoforms of the EML4-ALK transforming gene in non-small cell lung cancer. Cancer Res 68: 4971-4976. doi:10.1158/0008-5472.CAN-07-6158. PubMed: 18593892.
    • (2008) Cancer Res , vol.68 , pp. 4971-4976
    • Choi, Y.L.1    Takeuchi, K.2    Soda, M.3    Inamura, K.4    Togashi, Y.5
  • 15
    • 63949086127 scopus 로고    scopus 로고
    • KIF5B-ALK, a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer
    • doi:10.1158/1078-0432.CCR-08-3248
    • Takeuchi K, Choi YL, Togashi Y, Soda M, Hatano S, et al. (2009) KIF5B-ALK, a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer. Clin Cancer Res 15: 3143-3149. doi:10.1158/1078-0432.CCR-08-3248. PubMed: 19383809.
    • (2009) Clin Cancer Res , vol.15 , pp. 3143-3149
    • Takeuchi, K.1    Choi, Y.L.2    Togashi, Y.3    Soda, M.4    Hatano, S.5
  • 16
    • 79955973559 scopus 로고    scopus 로고
    • A novel KIF5B-ALK variant in nonsmall cell lung cancer
    • doi:10.1002/cncr.25843
    • Wong DW, Leung EL, Wong SK, Tin VP, Sihoe AD, et al. (2011) A novel KIF5B-ALK variant in nonsmall cell lung cancer. Cancer 117: 2709-2718. doi:10.1002/cncr.25843. PubMed: 21656749.
    • (2011) Cancer , vol.117 , pp. 2709-2718
    • Wong, D.W.1    Leung, E.L.2    Wong, S.K.3    Tin, V.P.4    Sihoe, A.D.5
  • 17
    • 84856695102 scopus 로고    scopus 로고
    • KLC1-ALK: a novel fusion in lung cancer identified using a formalin-fixed paraffin-embedded tissue only
    • doi:10.1371/journal.pone.0031323
    • Togashi Y, Soda M, Sakata S, Sugawara E, Hatano S, et al. (2012) KLC1-ALK: a novel fusion in lung cancer identified using a formalin-fixed paraffin-embedded tissue only. PLOS ONE 7: e31323. doi:10.1371/journal.pone.0031323. PubMed: 22347464.
    • (2012) PLOS ONE , vol.7
    • Togashi, Y.1    Soda, M.2    Sakata, S.3    Sugawara, E.4    Hatano, S.5
  • 18
    • 47649105190 scopus 로고    scopus 로고
    • EML4-ALK fusion transcripts, but no NPM-, TPM3-, CLTC-, ATIC-, or TFG-ALK fusion transcripts, in non-small cell lung carcinomas
    • doi:10.1016/j.lungcan.2007.12.013
    • Shinmura K, Kageyama S, Tao H, Bunai T, Suzuki M, et al. (2008) EML4-ALK fusion transcripts, but no NPM-, TPM3-, CLTC-, ATIC-, or TFG-ALK fusion transcripts, in non-small cell lung carcinomas. Lung Cancer 61: 163-169. doi:10.1016/j.lungcan.2007.12.013. PubMed: 18242762.
    • (2008) Lung Cancer , vol.61 , pp. 163-169
    • Shinmura, K.1    Kageyama, S.2    Tao, H.3    Bunai, T.4    Suzuki, M.5
  • 19
    • 37549060017 scopus 로고    scopus 로고
    • EML4-ALK fusion is linked to histological characteristics in a subset of lung cancers
    • doi:10.1097/JTO.0b013e31815e8b60
    • Inamura K, Takeuchi K, Togashi Y, Nomura K, Ninomiya H, et al. (2008) EML4-ALK fusion is linked to histological characteristics in a subset of lung cancers. J Thorac Oncol 3: 13-17. doi:10.1097/JTO.0b013e31815e8b60. PubMed: 18166835.
    • (2008) J Thorac Oncol , vol.3 , pp. 13-17
    • Inamura, K.1    Takeuchi, K.2    Togashi, Y.3    Nomura, K.4    Ninomiya, H.5
  • 20
    • 57349113565 scopus 로고    scopus 로고
    • Multiplex reverse transcription-PCR screening for EML4-ALK fusion transcripts
    • doi:10.1158/1078-0432.CCR-08-1018
    • Takeuchi K, Choi YL, Soda M, Inamura K, Togashi Y, et al. (2008) Multiplex reverse transcription-PCR screening for EML4-ALK fusion transcripts. Clin Cancer Res 14: 6618-6624. doi:10.1158/1078-0432.CCR-08-1018. PubMed: 18927303.
    • (2008) Clin Cancer Res , vol.14 , pp. 6618-6624
    • Takeuchi, K.1    Choi, Y.L.2    Soda, M.3    Inamura, K.4    Togashi, Y.5
  • 21
    • 48249114422 scopus 로고    scopus 로고
    • EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer
    • doi:10.1158/1078-0432.CCR-08-0168
    • Koivunen JP, Mermel C, Zejnullahu K, Murphy C, Lifshits E, et al. (2008) EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer. Clin Cancer Res 14: 4275-4283. doi:10.1158/1078-0432.CCR-08-0168. PubMed: 18594010.
    • (2008) Clin Cancer Res , vol.14 , pp. 4275-4283
    • Koivunen, J.P.1    Mermel, C.2    Zejnullahu, K.3    Murphy, C.4    Lifshits, E.5
  • 22
    • 63949087355 scopus 로고    scopus 로고
    • EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology, and young onset
    • doi:10.1038/modpathol.2009.2
    • Inamura K, Takeuchi K, Togashi Y, Hatano S, Ninomiya H, et al. (2009) EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology, and young onset. Mod Pathol 22: 508-515. doi:10.1038/modpathol.2009.2. PubMed: 19234440.
    • (2009) Mod Pathol , vol.22 , pp. 508-515
    • Inamura, K.1    Takeuchi, K.2    Togashi, Y.3    Hatano, S.4    Ninomiya, H.5
  • 23
    • 70349510460 scopus 로고    scopus 로고
    • Exon array profiling detects EML4-ALK fusion in breast, colorectal, and non-small cell lung cancers
    • doi:10.1158/1541-7786.MCR-08-0522
    • Lin E, Li L, Guan Y, Soriano R, Rivers CS, et al. (2009) Exon array profiling detects EML4-ALK fusion in breast, colorectal, and non-small cell lung cancers. Mol Cancer Res 7: 1466-1476. doi:10.1158/1541-7786.MCR-08-0522. PubMed: 19737969.
    • (2009) Mol Cancer Res , vol.7 , pp. 1466-1476
    • Lin, E.1    Li, L.2    Guan, Y.3    Soriano, R.4    Rivers, C.S.5
  • 24
    • 65249095599 scopus 로고    scopus 로고
    • The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS
    • doi:10.1002/cncr.24181
    • Wong DW, Leung EL, So KK, Tam IY, Sihoe AD, et al. (2009) The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS. Cancer 115: 1723-1733. doi:10.1002/cncr.24181. PubMed: 19170230.
    • (2009) Cancer , vol.115 , pp. 1723-1733
    • Wong, D.W.1    Leung, E.L.2    So, K.K.3    Tam, I.Y.4    Sihoe, A.D.5
  • 25
    • 59649127007 scopus 로고    scopus 로고
    • EML4-ALK rearrangement in non-small cell lung cancer and non-tumor lung tissues
    • doi:10.2353/ajpath.2009.080755
    • Martelli MP, Sozzi G, Hernandez L, Pettirossi V, Navarro A, et al. (2009) EML4-ALK rearrangement in non-small cell lung cancer and non-tumor lung tissues. Am J Pathol 174: 661-670. doi:10.2353/ajpath.2009.080755. PubMed: 19147828.
    • (2009) Am J Pathol , vol.174 , pp. 661-670
    • Martelli, M.P.1    Sozzi, G.2    Hernandez, L.3    Pettirossi, V.4    Navarro, A.5
  • 26
    • 77149130499 scopus 로고    scopus 로고
    • Clinicopathologic features of non-small-cell lung cancer with EML4-ALK fusion gene
    • doi:10.1245/s10434-009-0808-7
    • Takahashi T, Sonobe M, Kobayashi M, Yoshizawa A, Menju T, et al. (2010) Clinicopathologic features of non-small-cell lung cancer with EML4-ALK fusion gene. Ann Surg Oncol 17: 889-897. doi:10.1245/s10434-009-0808-7. PubMed: 20183914.
    • (2010) Ann Surg Oncol , vol.17 , pp. 889-897
    • Takahashi, T.1    Sonobe, M.2    Kobayashi, M.3    Yoshizawa, A.4    Menju, T.5
  • 27
    • 77954399760 scopus 로고    scopus 로고
    • Fusion of EML4 and ALK is associated with development of lung adenocarcinomas lacking EGFR and KRAS mutations and is correlated with ALK expression
    • doi:10.1186/1476-4598-9-188
    • Zhang X, Zhang S, Yang X, Yang J, Zhou Q, et al. (2010) Fusion of EML4 and ALK is associated with development of lung adenocarcinomas lacking EGFR and KRAS mutations and is correlated with ALK expression. Mol Cancer 9: 188. doi:10.1186/1476-4598-9-188. PubMed: 20624322.
    • (2010) Mol Cancer , vol.9 , pp. 188
    • Zhang, X.1    Zhang, S.2    Yang, X.3    Yang, J.4    Zhou, Q.5
  • 28
    • 79955656623 scopus 로고    scopus 로고
    • Exon scanning by reverse transcriptase-polymerase chain reaction for detection of known and novel EML4-ALK fusion variants in non-small cell lung cancer
    • doi:10.1016/j.cancergencyto.2010.08.024
    • Sanders HR, Li HR, Bruey JM, Scheerle JA, Meloni-Ehrig AM, et al. (2011) Exon scanning by reverse transcriptase-polymerase chain reaction for detection of known and novel EML4-ALK fusion variants in non-small cell lung cancer. Cancer Genet 204: 45-52. doi:10.1016/j.cancergencyto.2010.08.024. PubMed: 21356191.
    • (2011) Cancer Genet , vol.204 , pp. 45-52
    • Sanders, H.R.1    Li, H.R.2    Bruey, J.M.3    Scheerle, J.A.4    Meloni-Ehrig, A.M.5
  • 29
    • 78049425319 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
    • doi:10.1056/NEJMoa1006448
    • Kwak EL, Bang YJ, Camidge DR, Shaw AT, Solomon B, et al. (2010) Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med 363: 1693-1703. doi:10.1056/NEJMoa1006448. PubMed: 20979469.
    • (2010) N Engl J Med , vol.363 , pp. 1693-1703
    • Kwak, E.L.1    Bang, Y.J.2    Camidge, D.R.3    Shaw, A.T.4    Solomon, B.5
  • 30
    • 80052492099 scopus 로고    scopus 로고
    • Progression-free survival (PFS) from a phase I study of crizotinib (PF-02341066) in patients with ALK-positive non-small cell lung cancer (NSCLC)
    • abstr 2501
    • Camidge DR, Bang Y, Kwak EL, Shaw AT, Lafrate AJ, et al. (2011) Progression-free survival (PFS) from a phase I study of crizotinib (PF-02341066) in patients with ALK-positive non-small cell lung cancer (NSCLC). J Clin Oncol 29 (suppl): abstr 2501.
    • (2011) J Clin Oncol , vol.29 , Issue.SUPPL.
    • Camidge, D.R.1    Bang, Y.2    Kwak, E.L.3    Shaw, A.T.4    Lafrate, A.J.5
  • 31
    • 80051780280 scopus 로고    scopus 로고
    • Initial phase II results with crizotinib in advanced ALK-positive non-small cell lung cancer (NSCLC): PROFILE
    • abstr 7514
    • Crinò L, Kim D, Riely GJ, Janne PA, Blackhall FH, et al. (2011) Initial phase II results with crizotinib in advanced ALK-positive non-small cell lung cancer (NSCLC): PROFILE. J Clin Oncol 1005 (29 suppl):: abstr 7514.
    • (2011) J Clin Oncol , vol.1005 , Issue.29 SUPPL.
    • Crinò, L.1    Kim, D.2    Riely, G.J.3    Janne, P.A.4    Blackhall, F.H.5
  • 32
    • 84859124139 scopus 로고    scopus 로고
    • Crizotinib: a novel and first-in-class multitargeted tyrosine kinase inhibitor for the treatment of anaplastic lymphoma kinase rearranged non-small cell lung cancer and beyond
    • 22162641
    • Ou SH, (2011) Crizotinib: a novel and first-in-class multitargeted tyrosine kinase inhibitor for the treatment of anaplastic lymphoma kinase rearranged non-small cell lung cancer and beyond. Drugs Devel Ther 5: 471-485. PubMed: 22162641.
    • (2011) Drugs Devel Ther , vol.5 , pp. 471-485
    • Ou, S.H.1
  • 33
    • 0030034745 scopus 로고    scopus 로고
    • High incidence of the t(2;5)(p23;q35) translocation in anaplastic large cell lymphoma and its lack of detection in Hodgkin's disease. Comparison of cytogenetic analysis, reverse transcriptase-polymerase chain reaction, and P-80 immunostaining
    • 8547653
    • Lamant L, Meggetto F, al Saati T, Brugières L, de Paillerets BB, et al. (1996) High incidence of the t(2;5)(p23;q35) translocation in anaplastic large cell lymphoma and its lack of detection in Hodgkin's disease. Comparison of cytogenetic analysis, reverse transcriptase-polymerase chain reaction, and P-80 immunostaining. Blood 87: 284-291. PubMed: 8547653.
    • (1996) Blood , vol.87 , pp. 284-291
    • Lamant, L.1    Meggetto, F.2    al Saati, T.3    Brugières, L.4    de Paillerets, B.B.5
  • 34
    • 0031055562 scopus 로고    scopus 로고
    • Detection of anaplastic lymphoma kinase (ALK) and nucleolar protein nucleophosmin (NPM)-ALK proteins in normal and neoplastic cells with the monoclonal antibody ALK1
    • 9028963
    • Pulford K, Lamant L, Morris SW, Butler LH, Wood KM, et al. (1997) Detection of anaplastic lymphoma kinase (ALK) and nucleolar protein nucleophosmin (NPM)-ALK proteins in normal and neoplastic cells with the monoclonal antibody ALK1. Blood 89: 1394-1404. PubMed: 9028963.
    • (1997) Blood , vol.89 , pp. 1394-1404
    • Pulford, K.1    Lamant, L.2    Morris, S.W.3    Butler, L.H.4    Wood, K.M.5
  • 35
    • 78649633452 scopus 로고    scopus 로고
    • Combination of morphological feature analysis and immunohistochemistry is useful for screening of EML4-ALK-positive lung adenocarcinoma
    • doi:10.1136/jcp.2010.081166
    • Jokoji R, Yamasaki T, Minami S, Komuta K, Sakamaki Y, Takeuchi K, Tsujimoto M, (2010) Combination of morphological feature analysis and immunohistochemistry is useful for screening of EML4-ALK-positive lung adenocarcinoma. J Clin Pathol 63: 1066-1070. doi:10.1136/jcp.2010.081166. PubMed: 20935334.
    • (2010) J Clin Pathol , vol.63 , pp. 1066-1070
    • Jokoji, R.1    Yamasaki, T.2    Minami, S.3    Komuta, K.4    Sakamaki, Y.5    Takeuchi, K.6    Tsujimoto, M.7
  • 36
    • 79951769488 scopus 로고    scopus 로고
    • Screening of anaplastic lymphoma kinase rearrangement by immunohistochemistry in non-small cell lung cancer: correlation with fluorescence in situ hybridization
    • doi:10.1097/JTO.0b013e31820b82e8
    • Paik JH, Choe G, Kim H, Choe JY, Lee HJ, et al. (2011) Screening of anaplastic lymphoma kinase rearrangement by immunohistochemistry in non-small cell lung cancer: correlation with fluorescence in situ hybridization. J Thorac Oncol 6: 466-472. doi:10.1097/JTO.0b013e31820b82e8. PubMed: 21258247.
    • (2011) J Thorac Oncol , vol.6 , pp. 466-472
    • Paik, J.H.1    Choe, G.2    Kim, H.3    Choe, J.Y.4    Lee, H.J.5
  • 37
    • 79951774364 scopus 로고    scopus 로고
    • Correlation of IHC and FISH for ALK gene rearrangement in non-small cell lung carcinoma: IHC score algorithm for FISH
    • doi:10.1097/JTO.0b013e318209edb9
    • Yi ES, Boland JM, Maleszewski JJ, Roden AC, Oliveira AM, et al. (2011) Correlation of IHC and FISH for ALK gene rearrangement in non-small cell lung carcinoma: IHC score algorithm for FISH. J Thorac Oncol 6: 459-465. doi:10.1097/JTO.0b013e318209edb9. PubMed: 21278610.
    • (2011) J Thorac Oncol , vol.6 , pp. 459-465
    • Yi, E.S.1    Boland, J.M.2    Maleszewski, J.J.3    Roden, A.C.4    Oliveira, A.M.5
  • 38
    • 84863784502 scopus 로고    scopus 로고
    • Immunohistochemical screening for anaplastic lymphoma kinase (ALK) rearrangement in advanced non-small cell lung cancer patients
    • doi:10.1016/j.lungcan.2012.03.004
    • Park HS, Lee JK, Kim DW, Kulig K, Kim TM, et al. (2012) Immunohistochemical screening for anaplastic lymphoma kinase (ALK) rearrangement in advanced non-small cell lung cancer patients. Lung Cancer 77: 288-292. doi:10.1016/j.lungcan.2012.03.004. PubMed: 22465695.
    • (2012) Lung Cancer , vol.77 , pp. 288-292
    • Park, H.S.1    Lee, J.K.2    Kim, D.W.3    Kulig, K.4    Kim, T.M.5
  • 39
    • 69349083935 scopus 로고    scopus 로고
    • Unique Clinicopathologic Features Characterize ALK-rearranged Lung Adenocarcinoma in the Western Population
    • doi:10.1158/1078-0432.CCR-09-0802
    • Rodig SJ, Mino-Kenudson M, Dacic S, Yeap BY, Shaw A, et al. (2009) Unique Clinicopathologic Features Characterize ALK-rearranged Lung Adenocarcinoma in the Western Population. Clin Cancer Res 15: 5216-5223. doi:10.1158/1078-0432.CCR-09-0802. PubMed: 19671850.
    • (2009) Clin Cancer Res , vol.15 , pp. 5216-5223
    • Rodig, S.J.1    Mino-Kenudson, M.2    Dacic, S.3    Yeap, B.Y.4    Shaw, A.5
  • 40
    • 84864296896 scopus 로고    scopus 로고
    • Immunohistochemistry to identify EGFR mutations or ALK rearrangements in patients with lung adenocarcinoma
    • doi:10.1093/annonc/mdr535
    • Hofman P, Ilie M, Hofman V, Roux S, Valent A, et al. (2012) Immunohistochemistry to identify EGFR mutations or ALK rearrangements in patients with lung adenocarcinoma. Ann Oncol 23: 1738-1743. doi:10.1093/annonc/mdr535. PubMed: 22100693.
    • (2012) Ann Oncol , vol.23 , pp. 1738-1743
    • Hofman, P.1    Ilie, M.2    Hofman, V.3    Roux, S.4    Valent, A.5
  • 41
    • 84864231379 scopus 로고    scopus 로고
    • Comparison of reverse transcription-polymerase chain reaction, immunohistochemistry, and fluorescence in situ hybridization methodologies for detection of echinoderm microtubule-associated proteinlike 4-anaplastic lymphoma kinase fusion-positive non-small cell lung carcinoma: implications for optimal clinical testing
    • doi:10.5858/arpa.2011-0321-OA
    • Wallander ML, Geiersbach KB, Tripp SR, Layfield LJ, (2012) Comparison of reverse transcription-polymerase chain reaction, immunohistochemistry, and fluorescence in situ hybridization methodologies for detection of echinoderm microtubule-associated proteinlike 4-anaplastic lymphoma kinase fusion-positive non-small cell lung carcinoma: implications for optimal clinical testing. Arch Pathol Lab Med 136: 796-803. doi:10.5858/arpa.2011-0321-OA. PubMed: 22742552.
    • (2012) Arch Pathol Lab Med , vol.136 , pp. 796-803
    • Wallander, M.L.1    Geiersbach, K.B.2    Tripp, S.R.3    Layfield, L.J.4
  • 42
    • 84865805847 scopus 로고    scopus 로고
    • Correlation of anaplastic lymphoma kinase overexpression and the EML4-ALK fusion gene in non-small cell lung cancer by immunohistochemical study
    • 22913857
    • Chen TD, Chang IC, Liu HP, Wu YC, Wang CL, et al. (2012) Correlation of anaplastic lymphoma kinase overexpression and the EML4-ALK fusion gene in non-small cell lung cancer by immunohistochemical study. Chang Gung Med J 35: 309-317. PubMed: 22913857.
    • (2012) Chang Gung Med J , vol.35 , pp. 309-317
    • Chen, T.D.1    Chang, I.C.2    Liu, H.P.3    Wu, Y.C.4    Wang, C.L.5
  • 43
    • 84872330303 scopus 로고    scopus 로고
    • Clinical significance of EML4-ALK fusion gene and association with EGFR and KRAS gene mutations in 208 Chinese patients with non-small cell lung cancer
    • doi:10.1371/journal.pone.0052093
    • Li Y, Li Y, Yang T, Wei S, Wang J, et al. (2013) Clinical significance of EML4-ALK fusion gene and association with EGFR and KRAS gene mutations in 208 Chinese patients with non-small cell lung cancer. PLOS ONE 8: e52093. doi:10.1371/journal.pone.0052093. PubMed: 23341890.
    • (2013) PLOS ONE , vol.8
    • Li, Y.1    Li, Y.2    Yang, T.3    Wei, S.4    Wang, J.5
  • 44
    • 84865776102 scopus 로고    scopus 로고
    • Differential protein stability and ALK inhibitor sensitivity of EML4-ALK fusion variants
    • doi:10.1158/1078-0432.CCR-11-3260
    • Heuckmann JM, Balke-Want H, Malchers F, Peifer M, Sos ML, et al. (2012) Differential protein stability and ALK inhibitor sensitivity of EML4-ALK fusion variants. Clin Cancer Res 18: 4682-4690. doi:10.1158/1078-0432.CCR-11-3260. PubMed: 22912387.
    • (2012) Clin Cancer Res , vol.18 , pp. 4682-4690
    • Heuckmann, J.M.1    Balke-Want, H.2    Malchers, F.3    Peifer, M.4    Sos, M.L.5
  • 45
    • 80052793410 scopus 로고    scopus 로고
    • A novel ALK secondary mutation and EGFR signaling cause resistance to ALK kinase inhibitors
    • doi:10.1158/0008-5472.CAN-11-1340
    • Sasaki T, Koivunen J, Ogino A, Yanagita M, Nikiforow S, et al. (2011) A novel ALK secondary mutation and EGFR signaling cause resistance to ALK kinase inhibitors. Cancer Res 71: 6051-6060. doi:10.1158/0008-5472.CAN-11-1340. PubMed: 21791641.
    • (2011) Cancer Res , vol.71 , pp. 6051-6060
    • Sasaki, T.1    Koivunen, J.2    Ogino, A.3    Yanagita, M.4    Nikiforow, S.5
  • 46
    • 84655164310 scopus 로고    scopus 로고
    • EML4-ALK translocation predicts better outcome in lung adenocarcinoma patients with wild-type EGFR
    • doi:10.1097/JTO.0b013e3182370e30
    • Wu SG, Kuo YW, Chang YL, Shih JY, Chen YH, et al. (2012) EML4-ALK translocation predicts better outcome in lung adenocarcinoma patients with wild-type EGFR. J Thorac Oncol 7: 98-104. doi:10.1097/JTO.0b013e3182370e30. PubMed: 22124476.
    • (2012) J Thorac Oncol , vol.7 , pp. 98-104
    • Wu, S.G.1    Kuo, Y.W.2    Chang, Y.L.3    Shih, J.Y.4    Chen, Y.H.5
  • 47
    • 19944426858 scopus 로고    scopus 로고
    • High frequency of epidermal growth factor receptor mutations with complex patterns in non-small cell lung cancers related to gefitinib responsiveness in Taiwan
    • doi:10.1158/1078-0432.CCR-04-1245
    • Huang SF, Liu HP, Li LH, Ku YC, Fu YN, et al. (2004) High frequency of epidermal growth factor receptor mutations with complex patterns in non-small cell lung cancers related to gefitinib responsiveness in Taiwan. Clin Cancer Res 10: 8195-8203. doi:10.1158/1078-0432.CCR-04-1245. PubMed: 15623594.
    • (2004) Clin Cancer Res , vol.10 , pp. 8195-8203
    • Huang, S.F.1    Liu, H.P.2    Li, L.H.3    Ku, Y.C.4    Fu, Y.N.5
  • 48
    • 58149385365 scopus 로고    scopus 로고
    • Reversed mutation rates of KRAS and EGFR genes in adenocarcinoma of the lung in Taiwan and their implications
    • doi:10.1002/cncr.23925
    • Wu CC, Hsu HY, Liu HP, Chang JW, Chen YT, et al. (2008) Reversed mutation rates of KRAS and EGFR genes in adenocarcinoma of the lung in Taiwan and their implications. Cancer 113 (supp).:: 3199-3208. doi:10.1002/cncr.23925. PubMed: 18932251.
    • (2008) Cancer , vol.113 , Issue.SUPPL. , pp. 3199-3208
    • Wu, C.C.1    Hsu, H.Y.2    Liu, H.P.3    Chang, J.W.4    Chen, Y.T.5


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