-
1
-
-
69949162760
-
Gefitinib or carboplatinpaclitaxel in pulmonary adenocarcinoma
-
Mok TS, Wu YL, Thongprasert S, et al. Gefitinib or carboplatinpaclitaxel in pulmonary adenocarcinoma. N Engl J Med 2009;361:947-957.
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 947-957
-
-
Mok, T.S.1
Wu, Y.L.2
Thongprasert, S.3
-
2
-
-
34547638047
-
Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
-
DOI 10.1038/nature05945, PII NATURE05945
-
Soda M, Choi YL, Enomoto M, et al. Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature 2007; 448:561-566. (Pubitemid 47206930)
-
(2007)
Nature
, vol.448
, Issue.7153
, pp. 561-566
-
-
Soda, M.1
Choi, Y.L.2
Enomoto, M.3
Takada, S.4
Yamashita, Y.5
Ishikawa, S.6
Fujiwara, S.-I.7
Watanabe, H.8
Kurashina, K.9
Hatanaka, H.10
Bando, M.11
Ohno, S.12
Ishikawa, Y.13
Aburatani, H.14
Niki, T.15
Sohara, Y.16
Sugiyama, Y.17
Mano, H.18
-
3
-
-
48249114422
-
EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer
-
Koivunen JP, Mermel C, Zejnullahu K, et al. EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer. Clin Cancer Res 2008;14:4275-4283.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 4275-4283
-
-
Koivunen, J.P.1
Mermel, C.2
Zejnullahu, K.3
-
4
-
-
70349336416
-
Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4- ALK
-
Shaw AT, Yeap BY, Mino-Kenudson M, et al. Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4- ALK. J Clin Oncol 2009;27:4247-4253.
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 4247-4253
-
-
Shaw, A.T.1
Yeap, B.Y.2
Mino-Kenudson, M.3
-
5
-
-
65249095599
-
The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS
-
Wong DW, Leung EL, So KK, et al. The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS. Cancer 2009;115:1723-1733.
-
(2009)
Cancer
, vol.115
, pp. 1723-1733
-
-
Wong, D.W.1
Leung, E.L.2
So, K.K.3
-
6
-
-
37549060017
-
EML4-ALK fusion is linked to histological characteristics in a subset of lung cancers
-
Inamura K, Takeuchi K, Togashi Y, et al. EML4-ALK fusion is linked to histological characteristics in a subset of lung cancers. J Thorac Oncol 2008;3:13-17.
-
(2008)
J. Thorac. Oncol.
, vol.3
, pp. 13-17
-
-
Inamura, K.1
Takeuchi, K.2
Togashi, Y.3
-
7
-
-
36849065315
-
Global Survey of Phosphotyrosine Signaling Identifies Oncogenic Kinases in Lung Cancer
-
DOI 10.1016/j.cell.2007.11.025, PII S009286740701522X
-
Rikova K, Guo A, Zeng Q, et al. Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. Cell 2007;131: 1190-1203. (Pubitemid 350235027)
-
(2007)
Cell
, vol.131
, Issue.6
, pp. 1190-1203
-
-
Rikova, K.1
Guo, A.2
Zeng, Q.3
Possemato, A.4
Yu, J.5
Haack, H.6
Nardone, J.7
Lee, K.8
Reeves, C.9
Li, Y.10
Hu, Y.11
Tan, Z.12
Stokes, M.13
Sullivan, L.14
Mitchell, J.15
Wetzel, R.16
MacNeill, J.17
Ren, J.M.18
Yuan, J.19
Bakalarski, C.E.20
Villen, J.21
Kornhauser, J.M.22
Smith, B.23
Li, D.24
Zhou, X.25
Gygi, S.P.26
Gu, T.-L.27
Polakiewicz, R.D.28
Rush, J.29
Comb, M.J.30
more..
-
8
-
-
69349083935
-
Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population
-
Rodig SJ, Mino-Kenudson M, Dacic S, et al. Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population. Clin Cancer Res 2009;15:5216-5223.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 5216-5223
-
-
Rodig, S.J.1
Mino-Kenudson, M.2
Dacic, S.3
-
9
-
-
63949087355
-
EML4-ALK lung cancers are characterized by rare other mutations a TTF-1 cell lineage an acinar histology and young onset
-
Inamura K, Takeuchi K, Togashi Y, et al. EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology, and young onset. Mod Pathol 2009;22:508-515.
-
(2009)
Mod. Pathol.
, vol.22
, pp. 508-515
-
-
Inamura, K.1
Takeuchi, K.2
Togashi, Y.3
-
10
-
-
63949086127
-
KIF5B-ALK a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer
-
Takeuchi K, Choi YL, Togashi Y, et al. KIF5B-ALK, a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer. Clin Cancer Res 2009;15:3143-3149.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3143-3149
-
-
Takeuchi, K.1
Choi, Y.L.2
Togashi, Y.3
-
11
-
-
67650441507
-
Anaplastic lymphoma kinase immunoreactivity correlates with ALK gene rearrangement and transcriptional up-regulation in non-small cell lung carcinomas
-
Boland JM, Erdogan S, Vasmatzis G, et al. Anaplastic lymphoma kinase immunoreactivity correlates with ALK gene rearrangement and transcriptional up-regulation in non-small cell lung carcinomas. Hum Pathol 2009;40:1152-1158.
-
(2009)
Hum. Pathol.
, vol.40
, pp. 1152-1158
-
-
Boland, J.M.1
Erdogan, S.2
Vasmatzis, G.3
-
12
-
-
78049515002
-
Lung adenocarcinoma from East Asian never-smokers is a disease largely defined by targetable oncogenic mutant kinases
-
Sun Y, Ren Y, Fang Z, et al. Lung adenocarcinoma from East Asian never-smokers is a disease largely defined by targetable oncogenic mutant kinases. J Clin Oncol 2010;28:4616-4620.
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 4616-4620
-
-
Sun, Y.1
Ren, Y.2
Fang, Z.3
-
13
-
-
78049425319
-
Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
-
Kwak EL, Bang YJ, Camidge DR, et al. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med 2010;363:1693-1703.
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 1693-1703
-
-
Kwak, E.L.1
Bang, Y.J.2
Camidge, D.R.3
-
14
-
-
70350140489
-
Clinical activity observed in a phase I dose escalation trial of an oral c-met and ALK inhibitor PF-02341066
-
Abstract 3509
-
Kwak EL, Camidge DR, Clark J, et al. Clinical activity observed in a phase I dose escalation trial of an oral c-met and ALK inhibitor, PF-02341066. J Clin Oncol 2009;27:Abstract 3509.
-
(2009)
J. Clin. Oncol.
, vol.27
-
-
Kwak, E.L.1
Camidge, D.R.2
Clark, J.3
-
15
-
-
77149130499
-
Clinicopathologic features of non-small-cell lung cancer with EML4-ALK fusion gene
-
Takahashi T, Sonobe M, Kobayashi M, et al. Clinicopathologic features of non-small-cell lung cancer with EML4-ALK fusion gene. Ann Surg Oncol 2010;17:889-897.
-
(2010)
Ann. Surg. Oncol.
, vol.17
, pp. 889-897
-
-
Takahashi, T.1
Sonobe, M.2
Kobayashi, M.3
-
16
-
-
77954399760
-
Fusion of EML4 and ALK is associated with development of lung adenocarcinomas lacking EGFR and KRAS mutations and is correlated with ALK expression
-
Zhang X, Zhang S, Yang X, et al. Fusion of EML4 and ALK is associated with development of lung adenocarcinomas lacking EGFR and KRAS mutations and is correlated with ALK expression. Mol Cancer 2010;9:188.
-
(2010)
Mol. Cancer
, vol.9
, pp. 188
-
-
Zhang, X.1
Zhang, S.2
Yang, X.3
-
17
-
-
58749093115
-
Frequent epidermal growth factor receptor gene mutations in malignant pleural effusion of lung adenocarcinoma
-
Wu SG, Gow CH, Yu CJ, et al. Frequent epidermal growth factor receptor gene mutations in malignant pleural effusion of lung adenocarcinoma. Eur Respir J 2008;32:924-930.
-
(2008)
Eur. Respir. J.
, vol.32
, pp. 924-930
-
-
Wu, S.G.1
Gow, C.H.2
Yu, C.J.3
-
18
-
-
54049153188
-
First- or second-line therapy with gefitinib produces equal survival in non-small cell lung cancer
-
Wu JY, Yu CJ, Yang CH, et al. First- or second-line therapy with gefitinib produces equal survival in non-small cell lung cancer. Am J Respir Crit Care Med 2008;178:847-853.
-
(2008)
Am. J. Respir. Crit. Care Med.
, vol.178
, pp. 847-853
-
-
Wu, J.Y.1
Yu, C.J.2
Yang, C.H.3
-
19
-
-
51049116207
-
Lung cancer with epidermal growth factor receptor exon 20 mutations is associated with poor gefitinib treatment response
-
Wu JY, Wu SG, Yang CH, et al. Lung cancer with epidermal growth factor receptor exon 20 mutations is associated with poor gefitinib treatment response. Clin Cancer Res 2008;14:4877-4882.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 4877-4882
-
-
Wu, J.Y.1
Wu, S.G.2
Yang, C.H.3
-
20
-
-
58749111646
-
Good response to gefitinib in lung adenocarcinoma of complex epidermal growth factor receptor EGFR mutations with the classical mutation pattern
-
Wu SG, Chang YL, Hsu YC, et al. Good response to gefitinib in lung adenocarcinoma of complex epidermal growth factor receptor (EGFR) mutations with the classical mutation pattern. Oncologist 2008;13: 1276-1284.
-
(2008)
Oncologist
, vol.13
, pp. 1276-1284
-
-
Wu, S.G.1
Chang, Y.L.2
Hsu, Y.C.3
-
21
-
-
15744373791
-
-
Lyon: IARC Press
-
Travis WDBE, Muller-Hermelink HK, Harris CC. Pathology and Genetics of Tumors of the Lung, Pleura, Thymus and Heart. Lyon: IARC Press, 2004.
-
(2004)
Pathology and Genetics of Tumors of the Lung, Pleura, Thymus and Heart
-
-
Travis, W.D.B.E.1
Muller-Hermelink, H.K.2
Harris, C.C.3
-
22
-
-
34548457234
-
The IASLC lung cancer staging project: Proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumours
-
DOI 10.1097/JTO.0b013e31812f3c1a, PII 0124389420070800000006
-
Goldstraw P, Crowley J, Chansky K, et al. The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours. J Thorac Oncol 2007;2:706-714. (Pubitemid 47357522)
-
(2007)
Journal of Thoracic Oncology
, vol.2
, Issue.8
, pp. 706-714
-
-
Goldstraw, P.1
Crowley, J.2
Chansky, K.3
Giroux, D.J.4
Groome, P.A.5
Rami-Porta, R.6
Postmus, P.E.7
Rusch, V.8
Sobin, L.9
-
24
-
-
57849117384
-
New response evaluation criteria in solid tumours: Revised recist guideline version 1.1
-
Eisenhauer EA, Therasse P, Bogaerts J, et al. New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer 2009;45:228-247.
-
(2009)
Eur. J. Cancer
, vol.45
, pp. 228-247
-
-
Eisenhauer, E.A.1
Therasse, P.2
Bogaerts, J.3
-
25
-
-
20244388126
-
Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence
-
DOI 10.1200/JCO.2005.00.992
-
Mitsudomi T, Kosaka T, Endoh H, et al. Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence. J Clin Oncol 2005;23:2513-2520. (Pubitemid 47050841)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.11
, pp. 2513-2520
-
-
Mitsudomi, T.1
Kosaka, T.2
Endoh, H.3
Horio, Y.4
Hida, T.5
Mori, S.6
Hatooka, S.7
Shinoda, M.8
Takahashi, T.9
Yatabe, Y.10
-
26
-
-
77953291664
-
The biology and treatment of EML4-ALK non-small cell lung cancer
-
Sasaki T, Rodig SJ, Chirieac LR, et al. The biology and treatment of EML4-ALK non-small cell lung cancer. Eur J Cancer 2010;46:1773-1780.
-
(2010)
Eur. J. Cancer
, vol.46
, pp. 1773-1780
-
-
Sasaki, T.1
Rodig, S.J.2
Chirieac, L.R.3
-
27
-
-
57149089886
-
EGFR mutations predict survival benefit from gefitinib in patients with advanced lung adenocarcinoma: A historical comparison of patients treated before and after gefitinib approval in Japan
-
Takano T, Fukui T, Ohe Y, et al. EGFR mutations predict survival benefit from gefitinib in patients with advanced lung adenocarcinoma: a historical comparison of patients treated before and after gefitinib approval in Japan. J Clin Oncol 2008;26:5589-5595.
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 5589-5595
-
-
Takano, T.1
Fukui, T.2
Ohe, Y.3
-
28
-
-
45749120442
-
Specific EGFR mutations predict treatment outcome of stage IIIB/IV patients with chemotherapy-naïve non-small-cell lung cancer receiving first-line gefitinib monotherapy
-
Yang CH, Yu CJ, Shih JY, et al. Specific EGFR mutations predict treatment outcome of stage IIIB/IV patients with chemotherapy-naïve non-small-cell lung cancer receiving first-line gefitinib monotherapy. J Clin Oncol 2008;26:2745-2753.
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 2745-2753
-
-
Yang, C.H.1
Yu, C.J.2
Shih, J.Y.3
-
29
-
-
58149385365
-
Reversed mutation rates of KRAS and EGFR genes in adenocarcinoma of the lung in Taiwan and their implications
-
Wu CC, Hsu HY, Liu HP, et al. Reversed mutation rates of KRAS and EGFR genes in adenocarcinoma of the lung in Taiwan and their implications. Cancer 2008;113:3199-3208.
-
(2008)
Cancer
, vol.113
, pp. 3199-3208
-
-
Wu, C.C.1
Hsu, H.Y.2
Liu, H.P.3
-
30
-
-
26644465742
-
Epidermal growth factor receptor expression status in lung cancer correlates with its mutation
-
DOI 10.1016/j.humpath.2005.08.007, PII S0046817705004466
-
Suzuki M, Shigematsu H, Hiroshima K, et al. Epidermal growth factor receptor expression status in lung cancer correlates with its mutation. Hum Pathol 2005;36:1127-1134. (Pubitemid 41443266)
-
(2005)
Human Pathology
, vol.36
, Issue.10
, pp. 1127-1134
-
-
Suzuki, M.1
Shigematsu, H.2
Hiroshima, K.3
Iizasa, T.4
Nakatani, Y.5
Minna, J.D.6
Gazdar, A.F.7
Fujisawa, T.8
-
31
-
-
33847091172
-
EGFR, ERBB2, and KRAS mutations in Korean non-small cell lung cancer patients
-
DOI 10.1016/j.cancergencyto.2006.10.007, PII S0165460806007060
-
Bae NC, Chae MH, Lee MH, et al. EGFR, ERBB2, and KRAS mutations in Korean non-small cell lung cancer patients. Cancer Genet Cytogenet 2007;173:107-113. (Pubitemid 46281348)
-
(2007)
Cancer Genetics and Cytogenetics
, vol.173
, Issue.2
, pp. 107-113
-
-
Bae, N.C.1
Chae, M.H.2
Lee, M.H.3
Kim, K.M.4
Lee, E.B.5
Kim, C.H.6
Park, T.-I.7
Han, S.B.8
Jheon, S.9
Jung, T.H.10
Park, J.Y.11
-
32
-
-
0031669403
-
Analysis of K-ras gene mutations in lung carcinomas: Correlation with gender histological subtypes and clinical outcome
-
Wang YC, Lee HS, Chen SK, et al. Analysis of K-ras gene mutations in lung carcinomas: correlation with gender, histological subtypes, and clinical outcome. J Cancer Res Clin Oncol 1998;124:517-522.
-
(1998)
J. Cancer Res. Clin. Oncol.
, vol.124
, pp. 517-522
-
-
Wang, Y.C.1
Lee, H.S.2
Chen, S.K.3
-
33
-
-
79953029071
-
Anaplastic lymphoma kinase gene rearrangements in non-small cell lung cancer are associated with prolonged progression-free survival on pemetrexed
-
Camidge DR, Kono SA, Lu X, et al. Anaplastic lymphoma kinase gene rearrangements in non-small cell lung cancer are associated with prolonged progression-free survival on pemetrexed. J Thorac Oncol 2011; 6:774-780.
-
(2011)
J. Thorac. Oncol.
, vol.6
, pp. 774-780
-
-
Camidge, D.R.1
Kono, S.A.2
Lu, X.3
-
34
-
-
80052261903
-
Anaplastic lymphoma kinase translocation: A predictive biomarker of pemetrexed in patients with non-small cell lung cancer
-
Lee JO, Kim TM, Lee SH, et al. Anaplastic lymphoma kinase translocation: A predictive biomarker of pemetrexed in patients with non-small cell lung cancer. J Thorac Oncol 2011;6:1474-1480.
-
(2011)
J. Thorac. Oncol.
, vol.6
, pp. 1474-1480
-
-
Lee, J.O.1
Kim, T.M.2
Lee, S.H.3
-
35
-
-
48549098388
-
Identification of novel isoforms of the EML4-ALK transforming gene in non-small cell lung cancer
-
Choi YL, Takeuchi K, Soda M, et al. Identification of novel isoforms of the EML4-ALK transforming gene in non-small cell lung cancer. Cancer Res 2008;68:4971-4976.
-
(2008)
Cancer Res.
, vol.68
, pp. 4971-4976
-
-
Choi, Y.L.1
Takeuchi, K.2
Soda, M.3
-
36
-
-
77649091118
-
A novel highly sensitive antibody allows for the routine detection of ALK-rearranged lung adenocarcinomas by standard immunohistochemistry
-
Mino-Kenudson M, Chirieac LR, Law K, et al. A novel, highly sensitive antibody allows for the routine detection of ALK-rearranged lung adenocarcinomas by standard immunohistochemistry. Clin Cancer Res 2010;16:1561-1571.
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 1561-1571
-
-
Mino-Kenudson, M.1
Chirieac, L.R.2
Law, K.3
-
37
-
-
79951769488
-
Screening of anaplastic lymphoma kinase rearrangement by immunohistochemistry in non-small cell lung cancer: Correlation with fluorescence in situ hybridization
-
Paik JH, Choe G, Kim H, et al. Screening of anaplastic lymphoma kinase rearrangement by immunohistochemistry in non-small cell lung cancer: correlation with fluorescence in situ hybridization. J Thorac Oncol 2011;6:466-472
-
(2011)
J. Thorac. Oncol.
, vol.6
, pp. 466-472
-
-
Paik, J.H.1
Choe, G.2
Kim, H.3
|