메뉴 건너뛰기




Volumn 7, Issue 1, 2012, Pages 98-104

EML4-ALK translocation predicts better outcome in lung adenocarcinoma patients with Wild-type EGFR

Author keywords

Adenocarcinoma; EGFR mutation; EML4 ALK; Lung cancer

Indexed keywords

ANAPLASTIC LYMPHOMA KINASE; ECHINODERM MICROTUBULE ASSOCIATED PROTEIN LIKE 4 ANAPLASTIC LYMPHOMA KINASE; EPIDERMAL GROWTH FACTOR RECEPTOR; K RAS PROTEIN; UNCLASSIFIED DRUG;

EID: 84655164310     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1097/JTO.0b013e3182370e30     Document Type: Article
Times cited : (91)

References (37)
  • 1
    • 69949162760 scopus 로고    scopus 로고
    • Gefitinib or carboplatinpaclitaxel in pulmonary adenocarcinoma
    • Mok TS, Wu YL, Thongprasert S, et al. Gefitinib or carboplatinpaclitaxel in pulmonary adenocarcinoma. N Engl J Med 2009;361:947-957.
    • (2009) N. Engl. J. Med. , vol.361 , pp. 947-957
    • Mok, T.S.1    Wu, Y.L.2    Thongprasert, S.3
  • 3
    • 48249114422 scopus 로고    scopus 로고
    • EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer
    • Koivunen JP, Mermel C, Zejnullahu K, et al. EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer. Clin Cancer Res 2008;14:4275-4283.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 4275-4283
    • Koivunen, J.P.1    Mermel, C.2    Zejnullahu, K.3
  • 4
    • 70349336416 scopus 로고    scopus 로고
    • Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4- ALK
    • Shaw AT, Yeap BY, Mino-Kenudson M, et al. Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4- ALK. J Clin Oncol 2009;27:4247-4253.
    • (2009) J. Clin. Oncol. , vol.27 , pp. 4247-4253
    • Shaw, A.T.1    Yeap, B.Y.2    Mino-Kenudson, M.3
  • 5
    • 65249095599 scopus 로고    scopus 로고
    • The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS
    • Wong DW, Leung EL, So KK, et al. The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS. Cancer 2009;115:1723-1733.
    • (2009) Cancer , vol.115 , pp. 1723-1733
    • Wong, D.W.1    Leung, E.L.2    So, K.K.3
  • 6
    • 37549060017 scopus 로고    scopus 로고
    • EML4-ALK fusion is linked to histological characteristics in a subset of lung cancers
    • Inamura K, Takeuchi K, Togashi Y, et al. EML4-ALK fusion is linked to histological characteristics in a subset of lung cancers. J Thorac Oncol 2008;3:13-17.
    • (2008) J. Thorac. Oncol. , vol.3 , pp. 13-17
    • Inamura, K.1    Takeuchi, K.2    Togashi, Y.3
  • 8
    • 69349083935 scopus 로고    scopus 로고
    • Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population
    • Rodig SJ, Mino-Kenudson M, Dacic S, et al. Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population. Clin Cancer Res 2009;15:5216-5223.
    • (2009) Clin. Cancer Res. , vol.15 , pp. 5216-5223
    • Rodig, S.J.1    Mino-Kenudson, M.2    Dacic, S.3
  • 9
    • 63949087355 scopus 로고    scopus 로고
    • EML4-ALK lung cancers are characterized by rare other mutations a TTF-1 cell lineage an acinar histology and young onset
    • Inamura K, Takeuchi K, Togashi Y, et al. EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology, and young onset. Mod Pathol 2009;22:508-515.
    • (2009) Mod. Pathol. , vol.22 , pp. 508-515
    • Inamura, K.1    Takeuchi, K.2    Togashi, Y.3
  • 10
    • 63949086127 scopus 로고    scopus 로고
    • KIF5B-ALK a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer
    • Takeuchi K, Choi YL, Togashi Y, et al. KIF5B-ALK, a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer. Clin Cancer Res 2009;15:3143-3149.
    • (2009) Clin Cancer Res , vol.15 , pp. 3143-3149
    • Takeuchi, K.1    Choi, Y.L.2    Togashi, Y.3
  • 11
    • 67650441507 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase immunoreactivity correlates with ALK gene rearrangement and transcriptional up-regulation in non-small cell lung carcinomas
    • Boland JM, Erdogan S, Vasmatzis G, et al. Anaplastic lymphoma kinase immunoreactivity correlates with ALK gene rearrangement and transcriptional up-regulation in non-small cell lung carcinomas. Hum Pathol 2009;40:1152-1158.
    • (2009) Hum. Pathol. , vol.40 , pp. 1152-1158
    • Boland, J.M.1    Erdogan, S.2    Vasmatzis, G.3
  • 12
    • 78049515002 scopus 로고    scopus 로고
    • Lung adenocarcinoma from East Asian never-smokers is a disease largely defined by targetable oncogenic mutant kinases
    • Sun Y, Ren Y, Fang Z, et al. Lung adenocarcinoma from East Asian never-smokers is a disease largely defined by targetable oncogenic mutant kinases. J Clin Oncol 2010;28:4616-4620.
    • (2010) J. Clin. Oncol. , vol.28 , pp. 4616-4620
    • Sun, Y.1    Ren, Y.2    Fang, Z.3
  • 13
    • 78049425319 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
    • Kwak EL, Bang YJ, Camidge DR, et al. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med 2010;363:1693-1703.
    • (2010) N. Engl. J. Med. , vol.363 , pp. 1693-1703
    • Kwak, E.L.1    Bang, Y.J.2    Camidge, D.R.3
  • 14
    • 70350140489 scopus 로고    scopus 로고
    • Clinical activity observed in a phase I dose escalation trial of an oral c-met and ALK inhibitor PF-02341066
    • Abstract 3509
    • Kwak EL, Camidge DR, Clark J, et al. Clinical activity observed in a phase I dose escalation trial of an oral c-met and ALK inhibitor, PF-02341066. J Clin Oncol 2009;27:Abstract 3509.
    • (2009) J. Clin. Oncol. , vol.27
    • Kwak, E.L.1    Camidge, D.R.2    Clark, J.3
  • 15
    • 77149130499 scopus 로고    scopus 로고
    • Clinicopathologic features of non-small-cell lung cancer with EML4-ALK fusion gene
    • Takahashi T, Sonobe M, Kobayashi M, et al. Clinicopathologic features of non-small-cell lung cancer with EML4-ALK fusion gene. Ann Surg Oncol 2010;17:889-897.
    • (2010) Ann. Surg. Oncol. , vol.17 , pp. 889-897
    • Takahashi, T.1    Sonobe, M.2    Kobayashi, M.3
  • 16
    • 77954399760 scopus 로고    scopus 로고
    • Fusion of EML4 and ALK is associated with development of lung adenocarcinomas lacking EGFR and KRAS mutations and is correlated with ALK expression
    • Zhang X, Zhang S, Yang X, et al. Fusion of EML4 and ALK is associated with development of lung adenocarcinomas lacking EGFR and KRAS mutations and is correlated with ALK expression. Mol Cancer 2010;9:188.
    • (2010) Mol. Cancer , vol.9 , pp. 188
    • Zhang, X.1    Zhang, S.2    Yang, X.3
  • 17
    • 58749093115 scopus 로고    scopus 로고
    • Frequent epidermal growth factor receptor gene mutations in malignant pleural effusion of lung adenocarcinoma
    • Wu SG, Gow CH, Yu CJ, et al. Frequent epidermal growth factor receptor gene mutations in malignant pleural effusion of lung adenocarcinoma. Eur Respir J 2008;32:924-930.
    • (2008) Eur. Respir. J. , vol.32 , pp. 924-930
    • Wu, S.G.1    Gow, C.H.2    Yu, C.J.3
  • 18
    • 54049153188 scopus 로고    scopus 로고
    • First- or second-line therapy with gefitinib produces equal survival in non-small cell lung cancer
    • Wu JY, Yu CJ, Yang CH, et al. First- or second-line therapy with gefitinib produces equal survival in non-small cell lung cancer. Am J Respir Crit Care Med 2008;178:847-853.
    • (2008) Am. J. Respir. Crit. Care Med. , vol.178 , pp. 847-853
    • Wu, J.Y.1    Yu, C.J.2    Yang, C.H.3
  • 19
    • 51049116207 scopus 로고    scopus 로고
    • Lung cancer with epidermal growth factor receptor exon 20 mutations is associated with poor gefitinib treatment response
    • Wu JY, Wu SG, Yang CH, et al. Lung cancer with epidermal growth factor receptor exon 20 mutations is associated with poor gefitinib treatment response. Clin Cancer Res 2008;14:4877-4882.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 4877-4882
    • Wu, J.Y.1    Wu, S.G.2    Yang, C.H.3
  • 20
    • 58749111646 scopus 로고    scopus 로고
    • Good response to gefitinib in lung adenocarcinoma of complex epidermal growth factor receptor EGFR mutations with the classical mutation pattern
    • Wu SG, Chang YL, Hsu YC, et al. Good response to gefitinib in lung adenocarcinoma of complex epidermal growth factor receptor (EGFR) mutations with the classical mutation pattern. Oncologist 2008;13: 1276-1284.
    • (2008) Oncologist , vol.13 , pp. 1276-1284
    • Wu, S.G.1    Chang, Y.L.2    Hsu, Y.C.3
  • 22
    • 34548457234 scopus 로고    scopus 로고
    • The IASLC lung cancer staging project: Proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumours
    • DOI 10.1097/JTO.0b013e31812f3c1a, PII 0124389420070800000006
    • Goldstraw P, Crowley J, Chansky K, et al. The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours. J Thorac Oncol 2007;2:706-714. (Pubitemid 47357522)
    • (2007) Journal of Thoracic Oncology , vol.2 , Issue.8 , pp. 706-714
    • Goldstraw, P.1    Crowley, J.2    Chansky, K.3    Giroux, D.J.4    Groome, P.A.5    Rami-Porta, R.6    Postmus, P.E.7    Rusch, V.8    Sobin, L.9
  • 24
    • 57849117384 scopus 로고    scopus 로고
    • New response evaluation criteria in solid tumours: Revised recist guideline version 1.1
    • Eisenhauer EA, Therasse P, Bogaerts J, et al. New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer 2009;45:228-247.
    • (2009) Eur. J. Cancer , vol.45 , pp. 228-247
    • Eisenhauer, E.A.1    Therasse, P.2    Bogaerts, J.3
  • 25
    • 20244388126 scopus 로고    scopus 로고
    • Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence
    • DOI 10.1200/JCO.2005.00.992
    • Mitsudomi T, Kosaka T, Endoh H, et al. Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence. J Clin Oncol 2005;23:2513-2520. (Pubitemid 47050841)
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.11 , pp. 2513-2520
    • Mitsudomi, T.1    Kosaka, T.2    Endoh, H.3    Horio, Y.4    Hida, T.5    Mori, S.6    Hatooka, S.7    Shinoda, M.8    Takahashi, T.9    Yatabe, Y.10
  • 26
    • 77953291664 scopus 로고    scopus 로고
    • The biology and treatment of EML4-ALK non-small cell lung cancer
    • Sasaki T, Rodig SJ, Chirieac LR, et al. The biology and treatment of EML4-ALK non-small cell lung cancer. Eur J Cancer 2010;46:1773-1780.
    • (2010) Eur. J. Cancer , vol.46 , pp. 1773-1780
    • Sasaki, T.1    Rodig, S.J.2    Chirieac, L.R.3
  • 27
    • 57149089886 scopus 로고    scopus 로고
    • EGFR mutations predict survival benefit from gefitinib in patients with advanced lung adenocarcinoma: A historical comparison of patients treated before and after gefitinib approval in Japan
    • Takano T, Fukui T, Ohe Y, et al. EGFR mutations predict survival benefit from gefitinib in patients with advanced lung adenocarcinoma: a historical comparison of patients treated before and after gefitinib approval in Japan. J Clin Oncol 2008;26:5589-5595.
    • (2008) J. Clin. Oncol. , vol.26 , pp. 5589-5595
    • Takano, T.1    Fukui, T.2    Ohe, Y.3
  • 28
    • 45749120442 scopus 로고    scopus 로고
    • Specific EGFR mutations predict treatment outcome of stage IIIB/IV patients with chemotherapy-naïve non-small-cell lung cancer receiving first-line gefitinib monotherapy
    • Yang CH, Yu CJ, Shih JY, et al. Specific EGFR mutations predict treatment outcome of stage IIIB/IV patients with chemotherapy-naïve non-small-cell lung cancer receiving first-line gefitinib monotherapy. J Clin Oncol 2008;26:2745-2753.
    • (2008) J. Clin. Oncol. , vol.26 , pp. 2745-2753
    • Yang, C.H.1    Yu, C.J.2    Shih, J.Y.3
  • 29
    • 58149385365 scopus 로고    scopus 로고
    • Reversed mutation rates of KRAS and EGFR genes in adenocarcinoma of the lung in Taiwan and their implications
    • Wu CC, Hsu HY, Liu HP, et al. Reversed mutation rates of KRAS and EGFR genes in adenocarcinoma of the lung in Taiwan and their implications. Cancer 2008;113:3199-3208.
    • (2008) Cancer , vol.113 , pp. 3199-3208
    • Wu, C.C.1    Hsu, H.Y.2    Liu, H.P.3
  • 32
    • 0031669403 scopus 로고    scopus 로고
    • Analysis of K-ras gene mutations in lung carcinomas: Correlation with gender histological subtypes and clinical outcome
    • Wang YC, Lee HS, Chen SK, et al. Analysis of K-ras gene mutations in lung carcinomas: correlation with gender, histological subtypes, and clinical outcome. J Cancer Res Clin Oncol 1998;124:517-522.
    • (1998) J. Cancer Res. Clin. Oncol. , vol.124 , pp. 517-522
    • Wang, Y.C.1    Lee, H.S.2    Chen, S.K.3
  • 33
    • 79953029071 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase gene rearrangements in non-small cell lung cancer are associated with prolonged progression-free survival on pemetrexed
    • Camidge DR, Kono SA, Lu X, et al. Anaplastic lymphoma kinase gene rearrangements in non-small cell lung cancer are associated with prolonged progression-free survival on pemetrexed. J Thorac Oncol 2011; 6:774-780.
    • (2011) J. Thorac. Oncol. , vol.6 , pp. 774-780
    • Camidge, D.R.1    Kono, S.A.2    Lu, X.3
  • 34
    • 80052261903 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase translocation: A predictive biomarker of pemetrexed in patients with non-small cell lung cancer
    • Lee JO, Kim TM, Lee SH, et al. Anaplastic lymphoma kinase translocation: A predictive biomarker of pemetrexed in patients with non-small cell lung cancer. J Thorac Oncol 2011;6:1474-1480.
    • (2011) J. Thorac. Oncol. , vol.6 , pp. 1474-1480
    • Lee, J.O.1    Kim, T.M.2    Lee, S.H.3
  • 35
    • 48549098388 scopus 로고    scopus 로고
    • Identification of novel isoforms of the EML4-ALK transforming gene in non-small cell lung cancer
    • Choi YL, Takeuchi K, Soda M, et al. Identification of novel isoforms of the EML4-ALK transforming gene in non-small cell lung cancer. Cancer Res 2008;68:4971-4976.
    • (2008) Cancer Res. , vol.68 , pp. 4971-4976
    • Choi, Y.L.1    Takeuchi, K.2    Soda, M.3
  • 36
    • 77649091118 scopus 로고    scopus 로고
    • A novel highly sensitive antibody allows for the routine detection of ALK-rearranged lung adenocarcinomas by standard immunohistochemistry
    • Mino-Kenudson M, Chirieac LR, Law K, et al. A novel, highly sensitive antibody allows for the routine detection of ALK-rearranged lung adenocarcinomas by standard immunohistochemistry. Clin Cancer Res 2010;16:1561-1571.
    • (2010) Clin. Cancer Res. , vol.16 , pp. 1561-1571
    • Mino-Kenudson, M.1    Chirieac, L.R.2    Law, K.3
  • 37
    • 79951769488 scopus 로고    scopus 로고
    • Screening of anaplastic lymphoma kinase rearrangement by immunohistochemistry in non-small cell lung cancer: Correlation with fluorescence in situ hybridization
    • Paik JH, Choe G, Kim H, et al. Screening of anaplastic lymphoma kinase rearrangement by immunohistochemistry in non-small cell lung cancer: correlation with fluorescence in situ hybridization. J Thorac Oncol 2011;6:466-472
    • (2011) J. Thorac. Oncol. , vol.6 , pp. 466-472
    • Paik, J.H.1    Choe, G.2    Kim, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.