-
1
-
-
0035807592
-
Pregnancy-associated plasma protein A as a marker of acute coronary syndromes
-
Bayes-Genis A., Conover C.A., Overgaard M.T., Bailey K.R., Christiansen M., Holmes D.R., Virmani R., Oxvig C., Schwartz R.S. Pregnancy-associated plasma protein A as a marker of acute coronary syndromes. N. Engl. J. Med. 2001, 345:1022.
-
(2001)
N. Engl. J. Med.
, vol.345
, pp. 1022
-
-
Bayes-Genis, A.1
Conover, C.A.2
Overgaard, M.T.3
Bailey, K.R.4
Christiansen, M.5
Holmes, D.R.6
Virmani, R.7
Oxvig, C.8
Schwartz, R.S.9
-
2
-
-
0035097031
-
Insulin-like growth factor binding protein-4 protease produced by smooth muscle cells increases in the coronary artery after angioplasty
-
Bayes-Genis A., Schwartz R.S., Lewis D.A., Overgaard M.T., Christiansen M., Oxvig C., Ashai K., Holmes D.R., Conover C.A. Insulin-like growth factor binding protein-4 protease produced by smooth muscle cells increases in the coronary artery after angioplasty. Arterioscler. Thromb. Vasc. Biol. 2001, 21:335.
-
(2001)
Arterioscler. Thromb. Vasc. Biol.
, vol.21
, pp. 335
-
-
Bayes-Genis, A.1
Schwartz, R.S.2
Lewis, D.A.3
Overgaard, M.T.4
Christiansen, M.5
Oxvig, C.6
Ashai, K.7
Holmes, D.R.8
Conover, C.A.9
-
3
-
-
84871690459
-
Effects of mutated pregnancy-associated plasma protein-a on atherosclerotic lesion development in mice
-
Boldt H.B., Bale L.K., Resch Z.T., Oxvig C., Overgaard M.T., Conover C.A. Effects of mutated pregnancy-associated plasma protein-a on atherosclerotic lesion development in mice. Endocrinology 2013, 154:246.
-
(2013)
Endocrinology
, vol.154
, pp. 246
-
-
Boldt, H.B.1
Bale, L.K.2
Resch, Z.T.3
Oxvig, C.4
Overgaard, M.T.5
Conover, C.A.6
-
4
-
-
79953171500
-
Overexpression of pregnancy-associated plasma protein-A in ovarian cancer cells promotes tumor growth in vivo
-
Boldt H.B., Conover C.A. Overexpression of pregnancy-associated plasma protein-A in ovarian cancer cells promotes tumor growth in vivo. Endocrinology 2011, 152:1470.
-
(2011)
Endocrinology
, vol.152
, pp. 1470
-
-
Boldt, H.B.1
Conover, C.A.2
-
5
-
-
0035447508
-
Mutational analysis of the proteolytic domain of pregnancy-associated plasma protein-A (PAPP-A): classification as a metzincin
-
Boldt H.B., Overgaard M.T., Laursen L.S., Weyer K., Sottrup-Jensen L., Oxvig C. Mutational analysis of the proteolytic domain of pregnancy-associated plasma protein-A (PAPP-A): classification as a metzincin. Biochem. J. 2001, 358:359.
-
(2001)
Biochem. J.
, vol.358
, pp. 359
-
-
Boldt, H.B.1
Overgaard, M.T.2
Laursen, L.S.3
Weyer, K.4
Sottrup-Jensen, L.5
Oxvig, C.6
-
6
-
-
0028109920
-
Localization of pregnancy-associated plasma protein-A and colocalization of pregnancy-associated plasma protein-A messenger ribonucleic acid and eosinophil granule major basic protein messenger ribonucleic acid in placenta
-
Bonno M., Oxvig C., Kephart G.M., Wagner J.M., Kristensen T., Sottrup-Jensen L., Gleich G.J. Localization of pregnancy-associated plasma protein-A and colocalization of pregnancy-associated plasma protein-A messenger ribonucleic acid and eosinophil granule major basic protein messenger ribonucleic acid in placenta. Lab. Invest. 1994, 71:560.
-
(1994)
Lab. Invest.
, vol.71
, pp. 560
-
-
Bonno, M.1
Oxvig, C.2
Kephart, G.M.3
Wagner, J.M.4
Kristensen, T.5
Sottrup-Jensen, L.6
Gleich, G.J.7
-
7
-
-
65549101107
-
Relationship between pregnancy-associated plasma protein-A and lung cancer
-
Bulut I., Coskun A., Ciftci A., Cetinkaya E., Altiay G., Caglar T., Gulcan E. Relationship between pregnancy-associated plasma protein-A and lung cancer. Am. J. Med. Sci. 2009, 337:241.
-
(2009)
Am. J. Med. Sci.
, vol.337
, pp. 241
-
-
Bulut, I.1
Coskun, A.2
Ciftci, A.3
Cetinkaya, E.4
Altiay, G.5
Caglar, T.6
Gulcan, E.7
-
8
-
-
79961164621
-
Skp2B overexpression alters a prohibitin-p53 axis and the transcription of PAPP-A, the protease of insulin-like growth factor binding protein 4
-
Chander H., Halpern M., Resnick-Silverman L., Manfredi J.J., Germain D. Skp2B overexpression alters a prohibitin-p53 axis and the transcription of PAPP-A, the protease of insulin-like growth factor binding protein 4. PLoS One 2011, 6:e22456.
-
(2011)
PLoS One
, vol.6
-
-
Chander, H.1
Halpern, M.2
Resnick-Silverman, L.3
Manfredi, J.J.4
Germain, D.5
-
9
-
-
1642311220
-
Metalloproteinase pregnancy-associated plasma protein A is a critical growth regulatory factor during fetal development
-
Conover C.A., Bale L.K., Overgaard M.T., Johnstone E.W., Laursen U.H., Fuchtbauer E.M., Oxvig C., van Deursen J. Metalloproteinase pregnancy-associated plasma protein A is a critical growth regulatory factor during fetal development. Development 2004, 131:1187.
-
(2004)
Development
, vol.131
, pp. 1187
-
-
Conover, C.A.1
Bale, L.K.2
Overgaard, M.T.3
Johnstone, E.W.4
Laursen, U.H.5
Fuchtbauer, E.M.6
Oxvig, C.7
van Deursen, J.8
-
10
-
-
0029379551
-
Let's get specific: the relationship between specificity and affinity
-
Eaton B.E., Gold L., Zichi D.A. Let's get specific: the relationship between specificity and affinity. Chem. Biol. 1995, 2:633.
-
(1995)
Chem. Biol.
, vol.2
, pp. 633
-
-
Eaton, B.E.1
Gold, L.2
Zichi, D.A.3
-
12
-
-
34248338623
-
Quantification of proteolytically active pregnancy-associated plasma protein-A with an assay based on quenched fluorescence
-
Gyrup C., Christiansen M., Oxvig C. Quantification of proteolytically active pregnancy-associated plasma protein-A with an assay based on quenched fluorescence. Clin. Chem. 2007, 53:947.
-
(2007)
Clin. Chem.
, vol.53
, pp. 947
-
-
Gyrup, C.1
Christiansen, M.2
Oxvig, C.3
-
13
-
-
34250795031
-
Genetic deletion of pregnancy-associated plasma protein-A is associated with resistance to atherosclerotic lesion development in apolipoprotein E-deficient mice challenged with a high-fat diet
-
Harrington S.C., Simari R.D., Conover C.A. Genetic deletion of pregnancy-associated plasma protein-A is associated with resistance to atherosclerotic lesion development in apolipoprotein E-deficient mice challenged with a high-fat diet. Circ. Res. 2007, 100:1696.
-
(2007)
Circ. Res.
, vol.100
, pp. 1696
-
-
Harrington, S.C.1
Simari, R.D.2
Conover, C.A.3
-
14
-
-
79954614279
-
Targeting the insulin-like growth factor network in cancer therapy
-
Heidegger I., Pircher A., Klocker H., Massoner P. Targeting the insulin-like growth factor network in cancer therapy. Cancer Biol. Ther. 2011, 11:701.
-
(2011)
Cancer Biol. Ther.
, vol.11
, pp. 701
-
-
Heidegger, I.1
Pircher, A.2
Klocker, H.3
Massoner, P.4
-
15
-
-
84884321230
-
Identification of pregnancy-associated plasma protein A as a migration-promoting gene in malignant pleural mesothelioma cells: a potential therapeutic target
-
Huang J., Tabata S., Kakiuchi S., The Van T., Goto H., Hanibuchi M., Nishioka Y. Identification of pregnancy-associated plasma protein A as a migration-promoting gene in malignant pleural mesothelioma cells: a potential therapeutic target. Oncotarget 2013, 4:1172.
-
(2013)
Oncotarget
, vol.4
, pp. 1172
-
-
Huang, J.1
Tabata, S.2
Kakiuchi, S.3
The Van, T.4
Goto, H.5
Hanibuchi, M.6
Nishioka, Y.7
-
16
-
-
79651472165
-
Pregnancy associated plasma protein-A (PAPP-A) is not a marker of the vulnerable atherosclerotic plaque
-
Iversen K., Teisner A., Dalager S., Olsen K.E., Floridon C., Teisner B. Pregnancy associated plasma protein-A (PAPP-A) is not a marker of the vulnerable atherosclerotic plaque. Clin. Biochem. 2011, 44:312.
-
(2011)
Clin. Biochem.
, vol.44
, pp. 312
-
-
Iversen, K.1
Teisner, A.2
Dalager, S.3
Olsen, K.E.4
Floridon, C.5
Teisner, B.6
-
17
-
-
0037470496
-
Antibody multispecificity mediated by conformational diversity
-
James L.C., Roversi P., Tawfik D.S. Antibody multispecificity mediated by conformational diversity. Science 2003, 299:1362.
-
(2003)
Science
, vol.299
, pp. 1362
-
-
James, L.C.1
Roversi, P.2
Tawfik, D.S.3
-
18
-
-
0028958031
-
Insulin-like growth factors and their binding proteins: biological actions
-
Jones J.I., Clemmons D.R. Insulin-like growth factors and their binding proteins: biological actions. Endocr. Rev. 1995, 16:3.
-
(1995)
Endocr. Rev.
, vol.16
, pp. 3
-
-
Jones, J.I.1
Clemmons, D.R.2
-
19
-
-
0025823716
-
Identical V region amino acid sequences and segments of sequences in antibodies of different specificities. Relative contributions of VH and VL genes, minigenes, and complementarity-determining regions to binding of antibody-combining sites
-
Kabat E.A., Wu T.T. Identical V region amino acid sequences and segments of sequences in antibodies of different specificities. Relative contributions of VH and VL genes, minigenes, and complementarity-determining regions to binding of antibody-combining sites. J. Immunol. 1991, 147:1709.
-
(1991)
J. Immunol.
, vol.147
, pp. 1709
-
-
Kabat, E.A.1
Wu, T.T.2
-
20
-
-
0031759422
-
Proteolytic selection for protein folding using filamentous bacteriophages
-
Kristensen P., Winter G. Proteolytic selection for protein folding using filamentous bacteriophages. Fold. Des. 1998, 3:321.
-
(1998)
Fold. Des.
, vol.3
, pp. 321
-
-
Kristensen, P.1
Winter, G.2
-
22
-
-
0035943504
-
Pregnancy-associated plasma protein-A (PAPP-A) cleaves insulin-like growth factor binding protein (IGFBP)-5 independent of IGF: implications for the mechanism of IGFBP-4 proteolysis by PAPP-A
-
Laursen L.S., Overgaard M.T., Soe R., Boldt H.B., Sottrup-Jensen L., Giudice L.C., Conover C.A., Oxvig C. Pregnancy-associated plasma protein-A (PAPP-A) cleaves insulin-like growth factor binding protein (IGFBP)-5 independent of IGF: implications for the mechanism of IGFBP-4 proteolysis by PAPP-A. FEBS Lett. 2001, 504:36.
-
(2001)
FEBS Lett.
, vol.504
, pp. 36
-
-
Laursen, L.S.1
Overgaard, M.T.2
Soe, R.3
Boldt, H.B.4
Sottrup-Jensen, L.5
Giudice, L.C.6
Conover, C.A.7
Oxvig, C.8
-
23
-
-
0032981399
-
The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A
-
Lawrence J.B., Oxvig C., Overgaard M.T., Sottrup-Jensen L., Gleich G.J., Hays L.G., Yates J.R., Conover C.A. The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:3149.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 3149
-
-
Lawrence, J.B.1
Oxvig, C.2
Overgaard, M.T.3
Sottrup-Jensen, L.4
Gleich, G.J.5
Hays, L.G.6
Yates, J.R.7
Conover, C.A.8
-
24
-
-
0015991033
-
Characterization of four human pregnancy-associated plasma proteins
-
Lin T.M., Galbert S.P., Kiefer D., Spellacy W.N., Gall S. Characterization of four human pregnancy-associated plasma proteins. Am. J. Obstet. Gynecol. 1974, 118:223.
-
(1974)
Am. J. Obstet. Gynecol.
, vol.118
, pp. 223
-
-
Lin, T.M.1
Galbert, S.P.2
Kiefer, D.3
Spellacy, W.N.4
Gall, S.5
-
25
-
-
0030580057
-
Antibody-antigen interactions: contact analysis and binding site topography
-
MacCallum R.M., Martin A.C., Thornton J.M. Antibody-antigen interactions: contact analysis and binding site topography. J. Mol. Biol. 1996, 262:732.
-
(1996)
J. Mol. Biol.
, vol.262
, pp. 732
-
-
MacCallum, R.M.1
Martin, A.C.2
Thornton, J.M.3
-
26
-
-
0035099128
-
Human and murine immunoglobulin expression vector cassettes
-
McLean G.R., Nakouzi A., Casadevall A., Green N.S. Human and murine immunoglobulin expression vector cassettes. Mol. Immunol. 2000, 37:837.
-
(2000)
Mol. Immunol.
, vol.37
, pp. 837
-
-
McLean, G.R.1
Nakouzi, A.2
Casadevall, A.3
Green, N.S.4
-
27
-
-
47749087856
-
Inhibition of the proteolytic activity of pregnancy-associated plasma protein-A by targeting substrate exosite binding
-
Mikkelsen J.H., Gyrup C., Kristensen P., Overgaard M.T., Poulsen C.B., Laursen L.S., Oxvig C. Inhibition of the proteolytic activity of pregnancy-associated plasma protein-A by targeting substrate exosite binding. J. Biol. Chem. 2008, 283:16772.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 16772
-
-
Mikkelsen, J.H.1
Gyrup, C.2
Kristensen, P.3
Overgaard, M.T.4
Poulsen, C.B.5
Laursen, L.S.6
Oxvig, C.7
-
28
-
-
0037232811
-
Pregnancy-associated plasma protein-A is involved in insulin-like growth factor binding protein-2 (IGFBP-2) proteolytic degradation in bovine and porcine preovulatory follicles: identification of cleavage site and characterization of IGFBP-2 degradation
-
Monget P., Mazerbourg S., Delpuech T., Maurel M.C., Maniere S., Zapf J., Lalmanach G., Oxvig C., Overgaard M.T. Pregnancy-associated plasma protein-A is involved in insulin-like growth factor binding protein-2 (IGFBP-2) proteolytic degradation in bovine and porcine preovulatory follicles: identification of cleavage site and characterization of IGFBP-2 degradation. Biol. Reprod. 2003, 68:77.
-
(2003)
Biol. Reprod.
, vol.68
, pp. 77
-
-
Monget, P.1
Mazerbourg, S.2
Delpuech, T.3
Maurel, M.C.4
Maniere, S.5
Zapf, J.6
Lalmanach, G.7
Oxvig, C.8
Overgaard, M.T.9
-
29
-
-
0034613177
-
Expression of recombinant human pregnancy-associated plasma protein-A and identification of the proform of eosinophil major basic protein as its physiological inhibitor
-
Overgaard M.T., Haaning J., Boldt H.B., Olsen I.M., Laursen L.S., Christiansen M., Gleich G.J., Sottrup-Jensen L., Conover C.A., Oxvig C. Expression of recombinant human pregnancy-associated plasma protein-A and identification of the proform of eosinophil major basic protein as its physiological inhibitor. J. Biol. Chem. 2000, 275:31128.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 31128
-
-
Overgaard, M.T.1
Haaning, J.2
Boldt, H.B.3
Olsen, I.M.4
Laursen, L.S.5
Christiansen, M.6
Gleich, G.J.7
Sottrup-Jensen, L.8
Conover, C.A.9
Oxvig, C.10
-
30
-
-
0032859136
-
Messenger ribonucleic acid levels of pregnancy-associated plasma protein-A and the proform of eosinophil major basic protein: expression in human reproductive and nonreproductive tissues
-
Overgaard M.T., Oxvig C., Christiansen M., Lawrence J.B., Conover C.A., Gleich G.J., Sottrup-Jensen L., Haaning J. Messenger ribonucleic acid levels of pregnancy-associated plasma protein-A and the proform of eosinophil major basic protein: expression in human reproductive and nonreproductive tissues. Biol. Reprod. 1999, 61:1083.
-
(1999)
Biol. Reprod.
, vol.61
, pp. 1083
-
-
Overgaard, M.T.1
Oxvig, C.2
Christiansen, M.3
Lawrence, J.B.4
Conover, C.A.5
Gleich, G.J.6
Sottrup-Jensen, L.7
Haaning, J.8
-
31
-
-
84884889043
-
Pappalysin-1 (Pregnancy-Associated Plasma Protein-A)
-
Elsevier
-
Oxvig C. Pappalysin-1 (Pregnancy-Associated Plasma Protein-A). Handbook of Proteolytic Enzymes 2013, 1212. Elsevier.
-
(2013)
Handbook of Proteolytic Enzymes
, pp. 1212
-
-
Oxvig, C.1
-
32
-
-
0027164185
-
Circulating human pregnancy-associated plasma protein-A is disulfide-bridged to the proform of eosinophil major basic protein
-
Oxvig C., Sand O., Kristensen T., Gleich G.J., Sottrup-Jensen L. Circulating human pregnancy-associated plasma protein-A is disulfide-bridged to the proform of eosinophil major basic protein. J. Biol. Chem. 1993, 268:12243.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 12243
-
-
Oxvig, C.1
Sand, O.2
Kristensen, T.3
Gleich, G.J.4
Sottrup-Jensen, L.5
-
33
-
-
84869051269
-
Protein secretion is required for pregnancy-associated plasma protein-A to promote lung cancer growth in vivo
-
Pan H., Hanada S., Zhao J., Mao L., Ma M.Z. Protein secretion is required for pregnancy-associated plasma protein-A to promote lung cancer growth in vivo. PLoS One 2012, 7:e48799.
-
(2012)
PLoS One
, vol.7
-
-
Pan, H.1
Hanada, S.2
Zhao, J.3
Mao, L.4
Ma, M.Z.5
-
34
-
-
56749184290
-
Insulin and insulin-like growth factor signalling in neoplasia
-
Pollak M. Insulin and insulin-like growth factor signalling in neoplasia. Nat. Rev. Cancer 2008, 8:915.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 915
-
-
Pollak, M.1
-
35
-
-
77953457663
-
In vitro affinity maturation of HuCAL antibodies: complementarity determining region exchange and RapMAT technology
-
Prassler J., Steidl S., Urlinger S. In vitro affinity maturation of HuCAL antibodies: complementarity determining region exchange and RapMAT technology. Immunotherapy 2009, 1:571.
-
(2009)
Immunotherapy
, vol.1
, pp. 571
-
-
Prassler, J.1
Steidl, S.2
Urlinger, S.3
-
36
-
-
0031283462
-
Double-monoclonal immunofluorometric assays for pregnancy-associated plasma protein A/proeosinophil major basic protein (PAPP-A/proMBP) complex in first-trimester maternal serum screening for Down syndrome
-
Qin Q.P., Christiansen M., Oxvig C., Pettersson K., Sottrup-Jensen L., Koch C., Norgaard-Pedersen B. Double-monoclonal immunofluorometric assays for pregnancy-associated plasma protein A/proeosinophil major basic protein (PAPP-A/proMBP) complex in first-trimester maternal serum screening for Down syndrome. Clin. Chem. 1997, 43:2323.
-
(1997)
Clin. Chem.
, vol.43
, pp. 2323
-
-
Qin, Q.P.1
Christiansen, M.2
Oxvig, C.3
Pettersson, K.4
Sottrup-Jensen, L.5
Koch, C.6
Norgaard-Pedersen, B.7
-
37
-
-
67650588783
-
Expression of a protease-resistant insulin-like growth factor-binding protein-4 inhibits tumour growth in a murine model of breast cancer
-
Ryan A.J., Napoletano S., Fitzpatrick P.A., Currid C.A., O'Sullivan N.C., Harmey J.H. Expression of a protease-resistant insulin-like growth factor-binding protein-4 inhibits tumour growth in a murine model of breast cancer. Br. J. Cancer 2009, 101:278.
-
(2009)
Br. J. Cancer
, vol.101
, pp. 278
-
-
Ryan, A.J.1
Napoletano, S.2
Fitzpatrick, P.A.3
Currid, C.A.4
O'Sullivan, N.C.5
Harmey, J.H.6
-
38
-
-
33646897631
-
Pregnancy-associated plasma protein-a is markedly expressed by monocyte-macrophage cells in vulnerable and ruptured carotid atherosclerotic plaques: a link between inflammation and cerebrovascular events
-
Sangiorgi G., Mauriello A., Bonanno E., Oxvig C., Conover C.A., Christiansen M., Trimarchi S., Rampoldi V., Holmes D.R., Schwartz R.S., Spagnoli L.G. Pregnancy-associated plasma protein-a is markedly expressed by monocyte-macrophage cells in vulnerable and ruptured carotid atherosclerotic plaques: a link between inflammation and cerebrovascular events. J. Am. Coll. Cardiol. 2006, 47:2201.
-
(2006)
J. Am. Coll. Cardiol.
, vol.47
, pp. 2201
-
-
Sangiorgi, G.1
Mauriello, A.2
Bonanno, E.3
Oxvig, C.4
Conover, C.A.5
Christiansen, M.6
Trimarchi, S.7
Rampoldi, V.8
Holmes, D.R.9
Schwartz, R.S.10
Spagnoli, L.G.11
-
39
-
-
33748367666
-
Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins
-
Sitar T., Popowicz G.M., Siwanowicz I., Huber R., Holak T.A. Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:13028.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 13028
-
-
Sitar, T.1
Popowicz, G.M.2
Siwanowicz, I.3
Huber, R.4
Holak, T.A.5
-
40
-
-
0030821164
-
Structural insights into the evolution of an antibody combining site
-
Wedemayer G.J., Patten P.A., Wang L.H., Schultz P.G., Stevens R.C. Structural insights into the evolution of an antibody combining site. Science 1997, 276:1665.
-
(1997)
Science
, vol.276
, pp. 1665
-
-
Wedemayer, G.J.1
Patten, P.A.2
Wang, L.H.3
Schultz, P.G.4
Stevens, R.C.5
-
41
-
-
34249679099
-
A substrate specificity-determining unit of three Lin12-Notch repeat modules is formed in trans within the pappalysin-1 dimer and requires a sequence stretch C-terminal to the third module
-
Weyer K., Boldt H.B., Poulsen C.B., Kjaer-Sorensen K., Gyrup C., Oxvig C. A substrate specificity-determining unit of three Lin12-Notch repeat modules is formed in trans within the pappalysin-1 dimer and requires a sequence stretch C-terminal to the third module. J. Biol. Chem. 2007, 282:10988.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 10988
-
-
Weyer, K.1
Boldt, H.B.2
Poulsen, C.B.3
Kjaer-Sorensen, K.4
Gyrup, C.5
Oxvig, C.6
|