A human-specific mutation limits nonhuman primate efficacy in preclinical xenotransplantation studies

Transplantation

Volumn 97, Issue 4, 2014, Pages 385-390

  Waldman, Joshua P ^a   Brock, Linda G ^a   Rees, Michael A ^a  

^a UNIVERSITY OF TOLEDO MEDICAL CENTER   (United States)

Author keywords

Macrophages; Sialic acid and Nonhuman primates; Xenograft rejection

Indexed keywords

ANIMAL CELL; ARTICLE; CELL LOSS; CHIMPANZEE; CONTROLLED STUDY; ERYTHROCYTE; EXTRACORPOREAL CIRCULATION; GENE MUTATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER PERFUSION; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; SWINE; XENOTRANSPLANTATION;

ANIMALS; CELL MEMBRANE; DISEASE MODELS, ANIMAL; ERYTHROCYTES; GENE EXPRESSION; HUMANS; KUPFFER CELLS; LIVER; MACROPHAGES; MUTATION; N-ACETYLNEURAMINIC ACID; OXYGEN; PAN TROGLODYTES; PERFUSION; PHAGOCYTOSIS; PRIMATES; SIALIC ACID BINDING IG-LIKE LECTIN 1; SPECIES SPECIFICITY; SWINE; TRANSPLANTATION, HETEROLOGOUS;

EID: 84896733426     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.TP.0000441321.87915.82     Document Type: Article

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