Intravitreal injection of ranibizumab and CTGF shRNA improves retinal gene expression and microvessel ultrastructure in a rodent model of diabetes

International Journal of Molecular Sciences

Volumn 15, Issue 1, 2014, Pages 1606-1624

  Hu, Bojie ^a   Zhang, Yan ^a   Zeng, Qing ^a   Han, Qian ^a   Zhang, Lijuan ^a   Liu, Mian ^a   Li, Xiaorong ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

Connective tissue growth factor; Diabetic retinopathy; Ranibizumab; shRNA; Vascular endothelial growth factor

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; DNA DIRECTED RNA POLYMERASE III; PROTEIN KINASE C; RANIBIZUMAB; SHORT HAIRPIN RNA; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; GENE REGULATORY NETWORK; HETEROCHROMATIN; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MALE; MICROVASCULATURE; NONHUMAN; PHOTORECEPTOR; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RETINA DETACHMENT; RETINA MACULA CYSTOID EDEMA; RETINA NEOVASCULARIZATION; REVERSE TRANSCRIPTION; RNA EXTRACTION; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY; UPREGULATION;

ANIMALS; ANTIBODIES, MONOCLONAL, HUMANIZED; CONNECTIVE TISSUE GROWTH FACTOR; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC RETINOPATHY; HEK293 CELLS; HUMANS; INJECTIONS, INTRAOCULAR; MALE; RATS; RATS, SPRAGUE-DAWLEY; RETINA; RETINAL VESSELS; RNA, MESSENGER; RNA, SMALL INTERFERING; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84896731045     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms15011606     Document Type: Article

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