-
1
-
-
0031985028
-
Diabetic retinopathy
-
Aiello LP, Gardner TW, King GL, Blankenship G, Cavallerano JD, Ferris FL Klein R (1998 Diabetic retinopathy. Diabetes Care 21 : 143 156.
-
(1998)
Diabetes Care
, vol.21
, pp. 143-156
-
-
Aiello, L.P.1
Gardner, T.W.2
King, G.L.3
Blankenship, G.4
Cavallerano, J.D.5
Ferris, F.L.6
Klein, R.7
-
2
-
-
0037317423
-
A role for the polyol pathway in the early neuroretinal apoptosis and glial changes induced by diabetes in the rat
-
Asnaghi V, Gerhardinger C, Hoehn T, Adeboje A Lorenzi M (2003 A role for the polyol pathway in the early neuroretinal apoptosis and glial changes induced by diabetes in the rat. Diabetes 52 : 506 511.
-
(2003)
Diabetes
, vol.52
, pp. 506-511
-
-
Asnaghi, V.1
Gerhardinger, C.2
Hoehn, T.3
Adeboje, A.4
Lorenzi, M.5
-
3
-
-
0032913069
-
3, promotes endothelial cell survival, and induces angiogenesis in vivo
-
3, promotes endothelial cell survival, and induces angiogenesis in vivo. Mol Cell Biol 19 : 2958 2966.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 2958-2966
-
-
Babic, A.M.1
Chen, C.C.2
Lau, L.F.3
-
4
-
-
0032529103
-
Neural apoptosis in the retina during experimental and human diabetes: Early onset and effect of insulin
-
Barber AJ, Lieth E, Khin SA, Antonetti DA, Buchanan AG Gardner TW (1998 Neural apoptosis in the retina during experimental and human diabetes: early onset and effect of insulin. J Clin Invest 102 : 783 791.
-
(1998)
J Clin Invest
, vol.102
, pp. 783-791
-
-
Barber, A.J.1
Lieth, E.2
Khin, S.A.3
Antonetti, D.A.4
Buchanan, A.G.5
Gardner, T.W.6
-
5
-
-
22144457454
-
The Ins-Akita mouse as a model of early retinal complications in diabetes
-
Barber AJ, Antonetti DA, Kern TS et al. (2005 The Ins-Akita mouse as a model of early retinal complications in diabetes. Invest Ophthalmol Vis Sci 46 : 2210 2218.
-
(2005)
Invest Ophthalmol Vis Sci
, vol.46
, pp. 2210-2218
-
-
Barber, A.J.1
Antonetti, D.A.2
Kern, T.S.3
-
6
-
-
0036775477
-
Gene regulation of connective tissue growth factor: New targets for antifibrotic therapy?
-
Blom IE, Goldschmeding R Leask A (2002 Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy? Matrix Biol 21 : 473 482.
-
(2002)
Matrix Biol
, vol.21
, pp. 473-482
-
-
Blom, I.E.1
Goldschmeding, R.2
Leask, A.3
-
8
-
-
0036269326
-
The pathogenesis of diabetic retinopathy: Old concepts and new questions
-
Cai J Boulton M (2002 The pathogenesis of diabetic retinopathy: old concepts and new questions. Eye 16 : 242 260.
-
(2002)
Eye
, vol.16
, pp. 242-260
-
-
Cai, J.1
Boulton, M.2
-
9
-
-
0034726711
-
Activation of protein kinase C inhibits the expression of connective tissue growth factor
-
Fan WH Karnovsky MJ (2000 Activation of protein kinase C inhibits the expression of connective tissue growth factor. Biochem Biophys Res Commun 275 : 312 321.
-
(2000)
Biochem Biophys Res Commun
, vol.275
, pp. 312-321
-
-
Fan, W.H.1
Karnovsky, M.J.2
-
10
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE Mello CC (1998 Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391 : 806 811.
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
11
-
-
0029816069
-
Stimulation of fibroblast cell growth, matrix production, and granulation tissue formation by connective tissue growth factor
-
Frazier K, Williams S, Kothapalli D, Klapper H Grotendorst GR (1996 Stimulation of fibroblast cell growth, matrix production, and granulation tissue formation by connective tissue growth factor. J Invest Dermatol 107 : 404 411.
-
(1996)
J Invest Dermatol
, vol.107
, pp. 404-411
-
-
Frazier, K.1
Williams, S.2
Kothapalli, D.3
Klapper, H.4
Grotendorst, G.R.5
-
12
-
-
13944249469
-
Transforming growth factor-β2 modulated extracellular matrix component expression in cultured human optic nerve head astrocytes
-
Fuchshofer R, Birke M, Welge-Lussen U, Kook D Lütjen-Drecoll E (2005 Transforming growth factor-β2 modulated extracellular matrix component expression in cultured human optic nerve head astrocytes. Invest Ophthalmol Vis Sci 46 : 568 578.
-
(2005)
Invest Ophthalmol Vis Sci
, vol.46
, pp. 568-578
-
-
Fuchshofer, R.1
Birke, M.2
Welge-Lussen, U.3
Kook, D.4
Lütjen-Drecoll, E.5
-
13
-
-
33746729952
-
Loss of cholinergic and dopaminergic amacrine cells in streptozotocin-diabetic rat and Ins2Akita diabetic mouse retinas
-
Gastinger MJ, Singh RS Barber AJ (2006 Loss of cholinergic and dopaminergic amacrine cells in streptozotocin-diabetic rat and Ins2Akita diabetic mouse retinas. Invest Ophthalmol Vis Sci 47 : 3143 3150.
-
(2006)
Invest Ophthalmol Vis Sci
, vol.47
, pp. 3143-3150
-
-
Gastinger, M.J.1
Singh, R.S.2
Barber, A.J.3
-
14
-
-
0028881094
-
Tranilast inhibits the effects of platelet-derived growth factor on cell proliferation and induction of nitric oxide
-
Hishikawa K, Nakaki T, Hirahashi J, Marumo T Saruta T (1995 Tranilast inhibits the effects of platelet-derived growth factor on cell proliferation and induction of nitric oxide. Eur J Pharmacol 291 : 435 438.
-
(1995)
Eur J Pharmacol
, vol.291
, pp. 435-438
-
-
Hishikawa, K.1
Nakaki, T.2
Hirahashi, J.3
Marumo, T.4
Saruta, T.5
-
15
-
-
0035907365
-
Static pressure regulates connective tissue growth factor expression in human mesangial cells
-
Hishikawa K, Oemar BS Nakaki T (2001 Static pressure regulates connective tissue growth factor expression in human mesangial cells. J Biol Chem 276 : 16797 16803.
-
(2001)
J Biol Chem
, vol.276
, pp. 16797-16803
-
-
Hishikawa, K.1
Oemar, B.S.2
Nakaki, T.3
-
16
-
-
34147117767
-
Advanced glycation endproducts cause increased CCN family and extracellular gene expression in the diabetic rodent retina
-
Hughes JM, Kuiper EJ, Klaassen I et al. (2007 Advanced glycation endproducts cause increased CCN family and extracellular gene expression in the diabetic rodent retina. Diabetologia 50 : 1089 1098.
-
(2007)
Diabetologia
, vol.50
, pp. 1089-1098
-
-
Hughes, J.M.1
Kuiper, E.J.2
Klaassen, I.3
-
17
-
-
0032481302
-
High pressure conditions promote the proliferation of rat cultured mesangial cells in vitro
-
Kawata Y, Fujii Z, Sakumura T, Kitano M, Suzuki N Matsuzaki M (1998 High pressure conditions promote the proliferation of rat cultured mesangial cells in vitro. Biochim Biophys Acta 1401 : 195 202.
-
(1998)
Biochim Biophys Acta
, vol.1401
, pp. 195-202
-
-
Kawata, Y.1
Fujii, Z.2
Sakumura, T.3
Kitano, M.4
Suzuki, N.5
Matsuzaki, M.6
-
18
-
-
9644275599
-
Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: Therapeutic strategy for herpetic stromal keratitis
-
Kim B, Tang Q, Biswas PS et al. (2004 Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: therapeutic strategy for herpetic stromal keratitis. Am J Pathol 165 : 2177 2185.
-
(2004)
Am J Pathol
, vol.165
, pp. 2177-2185
-
-
Kim, B.1
Tang, Q.2
Biswas, P.S.3
-
19
-
-
33847076868
-
2 and connective tissue growth factor in proliferative vitreoretinal diseases, possible involvement of hyalocytes and therapeutic potential of rho kinase inhibitor
-
2 and connective tissue growth factor in proliferative vitreoretinal diseases, possible involvement of hyalocytes and therapeutic potential of rho kinase inhibitor. Diabetes 56 : 231 238.
-
(2007)
Diabetes
, vol.56
, pp. 231-238
-
-
Kita, T.1
Hata, Y.2
Kano, K.3
Miura, M.4
Nakao, S.5
Noda, Y.6
Shimokawa, H.7
Ishibashi, T.8
-
20
-
-
35148838025
-
Effect of VEGF-α on expression of profibrotic growth factor and extracellular matrix genes in the retina
-
Kuiper EJ, Hughes JM, Van Geest RJ, Vogels IM, Goldschmeding R, Van Noorden CJ, Schlingemann RO Klaassen I (2007 Effect of VEGF-α on expression of profibrotic growth factor and extracellular matrix genes in the retina. Invest Ophthalmol Vis Sci 48 : 4267 4276.
-
(2007)
Invest Ophthalmol Vis Sci
, vol.48
, pp. 4267-4276
-
-
Kuiper, E.J.1
Hughes, J.M.2
Van Geest, R.J.3
Vogels, I.M.4
Goldschmeding, R.5
Van Noorden, C.J.6
Schlingemann, R.O.7
Klaassen, I.8
-
21
-
-
2442693140
-
Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase: A role in high glucose-induced apoptosis in retinal Müller cells
-
Kusner LL, Sarthy VP Mohr S (2004 Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase: a role in high glucose-induced apoptosis in retinal Müller cells. Invest Ophthalmol Vis Sci 45 : 1553 1561.
-
(2004)
Invest Ophthalmol Vis Sci
, vol.45
, pp. 1553-1561
-
-
Kusner, L.L.1
Sarthy, V.P.2
Mohr, S.3
-
22
-
-
2242453283
-
1 in human umbilical vein endothelial cells
-
1 in human umbilical vein endothelial cells. J Biol Chem 277 : 46248 46255.
-
(2002)
J Biol Chem
, vol.277
, pp. 46248-46255
-
-
Leu, S.J.1
Lam, S.C.2
Lau, L.F.3
-
23
-
-
0034933340
-
Early cellular and molecular changes induced by diabetes in the retina
-
Lorenzi M Gerhardinger C (2001 Early cellular and molecular changes induced by diabetes in the retina. Diabetologia 44 : 791 804.
-
(2001)
Diabetologia
, vol.44
, pp. 791-804
-
-
Lorenzi, M.1
Gerhardinger, C.2
-
24
-
-
0036014909
-
Vascular endothelial growth factor gene regulation and action in diabetic retinopathy
-
Lu M Adamis AP (2002 Vascular endothelial growth factor gene regulation and action in diabetic retinopathy. Ophthalmol Clin North Am 15 : 69 79.
-
(2002)
Ophthalmol Clin North Am
, vol.15
, pp. 69-79
-
-
Lu, M.1
Adamis, A.P.2
-
25
-
-
4344573553
-
Death of retinal neurons in streptozotocin-induced diabetic mice
-
Martin PM, Roon P, Van Ells TK, Ganapathy V Smith SB (2004 Death of retinal neurons in streptozotocin-induced diabetic mice. Invest Ophthalmol Vis Sci 45 : 3330 3336.
-
(2004)
Invest Ophthalmol Vis Sci
, vol.45
, pp. 3330-3336
-
-
Martin, P.M.1
Roon, P.2
Van Ells, T.K.3
Ganapathy, V.4
Smith, S.B.5
-
26
-
-
0033605162
-
Suppression subtractive hybridization identifies high glucose levels as a stimulus for expression of connective tissue growth factor and other genes in human mesangial cells
-
Murphy M, Godson C, Cannon S, Kato S, Mackenzie HS, Martin F Brady HR (1999 Suppression subtractive hybridization identifies high glucose levels as a stimulus for expression of connective tissue growth factor and other genes in human mesangial cells. J Biol Chem 274 : 5830 5834.
-
(1999)
J Biol Chem
, vol.274
, pp. 5830-5834
-
-
Murphy, M.1
Godson, C.2
Cannon, S.3
Kato, S.4
MacKenzie, H.S.5
Martin, F.6
Brady, H.R.7
-
27
-
-
0035108843
-
Aminoguanidine and ramipril prevent diabetes-induced increases in protein kinase C activity in glomeruli, retina and mesenteric artery
-
Osicka TM, Yu Y, Lee V, Panagiotopoulos S, Kemp BE Jerums G (2001 Aminoguanidine and ramipril prevent diabetes-induced increases in protein kinase C activity in glomeruli, retina and mesenteric artery. Clin Sci 100 : 249 257.
-
(2001)
Clin Sci
, vol.100
, pp. 249-257
-
-
Osicka, T.M.1
Yu, Y.2
Lee, V.3
Panagiotopoulos, S.4
Kemp, B.E.5
Jerums, G.6
-
28
-
-
0141594635
-
Apoptotic death of photoreceptors in the streptozotocin-induced diabetic rat retina
-
Park SH, Park JW, Park SJ, Kim KY, Chung JW, Chun MH Oh SJ (2003 Apoptotic death of photoreceptors in the streptozotocin-induced diabetic rat retina. Diabetologia 46 : 1260 1268.
-
(2003)
Diabetologia
, vol.46
, pp. 1260-1268
-
-
Park, S.H.1
Park, J.W.2
Park, S.J.3
Kim, K.Y.4
Chung, J.W.5
Chun, M.H.6
Oh, S.J.7
-
29
-
-
0038748037
-
Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model
-
Reich SJ, Fosnot J, Kuroki A, Tang W, Yang X, Maguire AM, Bennett J Tolentino MJ (2003 Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model. Mol Vis 9 : 210 216.
-
(2003)
Mol Vis
, vol.9
, pp. 210-216
-
-
Reich, S.J.1
Fosnot, J.2
Kuroki, A.3
Tang, W.4
Yang, X.5
Maguire, A.M.6
Bennett, J.7
Tolentino, M.J.8
-
30
-
-
18744430508
-
Connective tissue growth factor is a mediator of angiotensin II-induced fibrosis
-
Ruperez M, Lorenzo O, Blanco-Colio LM, Esteban V, Egido J Ruiz-Ortega M (2003 Connective tissue growth factor is a mediator of angiotensin II-induced fibrosis. Circulation 108 : 1499 1505.
-
(2003)
Circulation
, vol.108
, pp. 1499-1505
-
-
Ruperez, M.1
Lorenzo, O.2
Blanco-Colio, L.M.3
Esteban, V.4
Egido, J.5
Ruiz-Ortega, M.6
-
31
-
-
0032817965
-
Connective tissue growth factor induces the proliferation, migration, and tube formation of vascular endothelial cells in vitro, and angiogenesis in vivo
-
Shimo T, Nakanishi T, Nishida T et al. (1999 Connective tissue growth factor induces the proliferation, migration, and tube formation of vascular endothelial cells in vitro, and angiogenesis in vivo. J Biochem 126 : 137 145.
-
(1999)
J Biochem
, vol.126
, pp. 137-145
-
-
Shimo, T.1
Nakanishi, T.2
Nishida, T.3
-
32
-
-
0035841946
-
Connective tissue growth factor as a major angiogenic agent that is induced by hypoxia in a human breast cancer cell line
-
Shimo T, Kubota S, Kondo S, Nakanishi T, Sasaki A, Mese H, Matsumura T Takigawa M (2001 Connective tissue growth factor as a major angiogenic agent that is induced by hypoxia in a human breast cancer cell line. Cancer Lett 174 : 57 64.
-
(2001)
Cancer Lett
, vol.174
, pp. 57-64
-
-
Shimo, T.1
Kubota, S.2
Kondo, S.3
Nakanishi, T.4
Sasaki, A.5
Mese, H.6
Matsumura, T.7
Takigawa, M.8
-
33
-
-
0034731522
-
Vascular endothelial growth factor induces expression of connective tissue growth factor via KDR, Flt1, and phosphatidylinositol 3-kinase-akt-dependent pathway in retinal vascular cells
-
Suzuma K, Naruse K, Suzuma I, Takahara N, Ueki K, Aiello LP King GL (2000 Vascular endothelial growth factor induces expression of connective tissue growth factor via KDR, Flt1, and phosphatidylinositol 3-kinase-akt-dependent pathway in retinal vascular cells. J Biol Chem 275 : 40725 40731.
-
(2000)
J Biol Chem
, vol.275
, pp. 40725-40731
-
-
Suzuma, K.1
Naruse, K.2
Suzuma, I.3
Takahara, N.4
Ueki, K.5
Aiello, L.P.6
King, G.L.7
-
34
-
-
0842313052
-
Connective tissue growth factor is upregulated in the diabetic retina: Amelioration by angiotensin-converting enzyme inhibition
-
Tikellis C, Cooper ME, Twigg SM, Burns WC Tolcos M (2004 Connective tissue growth factor is upregulated in the diabetic retina: amelioration by angiotensin-converting enzyme inhibition. Endocrinology 145 : 860 866.
-
(2004)
Endocrinology
, vol.145
, pp. 860-866
-
-
Tikellis, C.1
Cooper, M.E.2
Twigg, S.M.3
Burns, W.C.4
Tolcos, M.5
-
35
-
-
3142733601
-
The time has come to target connective tissue growth factor in diabetic complications
-
Twigg SM Cooper ME (2004 The time has come to target connective tissue growth factor in diabetic complications. Diabetologia 47 : 965 968.
-
(2004)
Diabetologia
, vol.47
, pp. 965-968
-
-
Twigg, S.M.1
Cooper, M.E.2
-
36
-
-
13444250205
-
Imbalance of growth factor signalling in diabetic kidney disease: Is connective tissue growth factor (CTGF, CCN2) the perfect intervention point?
-
Van Nieuwenhoven FA, Jensen LJ, Flyvbjerg A Goldschmeding R (2005 Imbalance of growth factor signalling in diabetic kidney disease: is connective tissue growth factor (CTGF, CCN2) the perfect intervention point? Nephrol Dial Transplant 20 : 6 10.
-
(2005)
Nephrol Dial Transplant
, vol.20
, pp. 6-10
-
-
Van Nieuwenhoven, F.A.1
Jensen, L.J.2
Flyvbjerg, A.3
Goldschmeding, R.4
-
37
-
-
27344453261
-
Detection of connective tissue growth factor in subretinal fluid following retinal detachment: Possible contribution to subretinal scar formation, preliminary results
-
Van Setten G, Berglin L, Blalock TD Schultz G (2005 Detection of connective tissue growth factor in subretinal fluid following retinal detachment: possible contribution to subretinal scar formation, preliminary results. Ophthalmic Res 37 : 289 292.
-
(2005)
Ophthalmic Res
, vol.37
, pp. 289-292
-
-
Van Setten, G.1
Berglin, L.2
Blalock, T.D.3
Schultz, G.4
-
38
-
-
0036177882
-
Gene expression and identification of gene therapy targets in diabetic nephropathy
-
Wada J, Makino H Kanwar YS (2002 Gene expression and identification of gene therapy targets in diabetic nephropathy. Kidney Int 61 (Suppl.) : 73 78.
-
(2002)
Kidney Int
, vol.61
, pp. 73-78
-
-
Wada, J.1
Makino, H.2
Kanwar, Y.S.3
-
39
-
-
0036187554
-
Altered expression patterns of VEGF receptors in human diabetic retina and in experimental VEGF-induced retinopathy in monkey
-
Witmer AN, Blaauwgeers HG, Weich HA, Alitalo K, Vrensen GF Schlingemann RO (2002 Altered expression patterns of VEGF receptors in human diabetic retina and in experimental VEGF-induced retinopathy in monkey. Invest Ophthalmol Vis Sci 43 : 849 857.
-
(2002)
Invest Ophthalmol Vis Sci
, vol.43
, pp. 849-857
-
-
Witmer, A.N.1
Blaauwgeers, H.G.2
Weich, H.A.3
Alitalo, K.4
Vrensen, G.F.5
Schlingemann, R.O.6
-
40
-
-
2542473312
-
Reduction in connective tissue growth factor by antisense treatment ameliorates renal tubulointerstitial fibrosis
-
Yokoi H, Mukoyama M, Nagae T et al. (2004 Reduction in connective tissue growth factor by antisense treatment ameliorates renal tubulointerstitial fibrosis. J Am Soc Nephrol 15 : 1430 1440.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 1430-1440
-
-
Yokoi, H.1
Mukoyama, M.2
Nagae, T.3
-
41
-
-
12344316708
-
Small interfering RNA inhibition of SPARC attenuates the profibrotic effect of transforming growth factor in cultured normal human fibroblasts
-
Zhou XD, Tan FK, Guo X, Wallis D, Milewicz DM, Xue S Arnett FC (2005 Small interfering RNA inhibition of SPARC attenuates the profibrotic effect of transforming growth factor in cultured normal human fibroblasts. Arthritis Rheum 52 : 57 61.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 57-61
-
-
Zhou, X.D.1
Tan, F.K.2
Guo, X.3
Wallis, D.4
Milewicz, D.M.5
Xue, S.6
Arnett, F.C.7
-
42
-
-
33845672611
-
SPARC, an upstream regulator of connective tissue growth factor in response to transforming growth factor-β stimulation
-
Zhou XD, Xiong MM, Tan FK, Guo XJ Arnett FC (2006 SPARC, an upstream regulator of connective tissue growth factor in response to transforming growth factor-β stimulation. Arthritis Rheum 54 : 3885 3889.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 3885-3889
-
-
Zhou, X.D.1
Xiong, M.M.2
Tan, F.K.3
Guo, X.J.4
Arnett, F.C.5
-
43
-
-
0035856920
-
Global and societal implications of the diabetes epidemic
-
Zimmet P, Alberti KG Shaw J (2001 Global and societal implications of the diabetes epidemic. Nature 414 : 782 787.
-
(2001)
Nature
, vol.414
, pp. 782-787
-
-
Zimmet, P.1
Alberti, K.G.2
Shaw, J.3
|