Dual-specificity phosphatase 14 (DUSP14/MKP6) negatively regulates TCR signaling by inhibiting TAB1 activation

Journal of Immunology

Volumn 192, Issue 4, 2014, Pages 1547-1557

  Yang, Chia Yu ^a   Li, Ju Pi ^a   Chiu, Li Li ^b   Lan, Joung Liang ^b,c   Chen, Der Yuan ^b,d   Chuang, Huai Chia ^a   Huang, Ching Yu ^a   Tan, Tse Hua ^a,e  

^a NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^b TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^c CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d NATIONAL YANG MING UNIVERSITY   (Taiwan)

^e BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; DUAL SPECIFICITY PHOSPHATASE; DUAL SPECIFICITY PHOSPHATASE 14; GAMMA INTERFERON; I KAPPA B KINASE; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2B; IMMUNOGLOBULIN M; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 4; SERINE; SHORT HAIRPIN RNA; STRESS ACTIVATED PROTEIN KINASE; T LYMPHOCYTE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1 BINDING PROTEIN 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE PREDISPOSITION; EMBRYO; ENZYME ACTIVATION; ENZYME DEFICIENCY; ENZYME INACTIVATION; ENZYME REGULATION; EXPERIMENTAL AUTOIMMUNE MYASTHENIA GRAVIS; FEMALE; GENE SILENCING; IMMUNE RESPONSE; INHIBITION KINETICS; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN INTERACTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; DUAL-SPECIFICITY PHOSPHATASES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ENZYME ACTIVATION; HUMANS; I-KAPPA B KINASE; INTERFERON-GAMMA; INTERLEUKIN-2; INTERLEUKIN-4; JNK MITOGEN-ACTIVATED PROTEIN KINASES; JURKAT CELLS; LYMPHOCYTE ACTIVATION; MAP KINASE KINASE KINASES; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MULTIPROTEIN COMPLEXES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN BINDING; RECEPTORS, ANTIGEN, T-CELL; RNA INTERFERENCE; RNA, SMALL INTERFERING; TH1 CELLS; TH17 CELLS; TRANSFORMING GROWTH FACTOR BETA;

EID: 84896729300     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1300989     Document Type: Article

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