Down-regulation of B cell receptor signaling by hematopoietic progenitor kinase 1 (HPK1)-mediated phosphorylation and ubiquitination of activated B cell linker protein (BLNK)

Journal of Biological Chemistry

Volumn 287, Issue 14, 2012, Pages 11037-11048

  Wang, Xiaohong ^a   Li, Ju Pi ^b   Kuo, Hui Kai ^b   Chiu, Li Li ^c   Dement, Gregory A ^a   Lan, Joung Liang ^c,d   Chen, Der Yuan ^c,d   Yang, Chia Yu ^b   Hu, Hongbo ^a   Tan, Tse Hua ^a,b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^c TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^d NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

B CELL RECEPTOR; B CELLS; CELL ACTIVATION; DOWN-REGULATION; IMMUNE RESPONSE; KINASE ACTIVATION; LINKER PROTEINS; LYSINE RESIDUES; UBIQUITINATION;

AMINO ACIDS; CELL MEMBRANES; CHEMICAL ACTIVATION; ENZYMES; PHOSPHORYLATION;

SIGNALING;

B CELL LINKER PROTEIN; B LYMPHOCYTE RECEPTOR; CELL PROTEIN; HEMATOPOIETIC PROGENITOR KINASE 1; I KAPPA B; I KAPPA B KINASE; LYSINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN 14 3 3; PROTEIN SERINE THREONINE KINASE; STRESS ACTIVATED PROTEIN KINASE; THREONINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOIMMUNE DISEASE; B LYMPHOCYTE ACTIVATION; CELL ISOLATION; CELL MATURATION; CELL STIMULATION; CELL STRAIN HEK293; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; IN VITRO STUDY; INTRACELLULAR SIGNALING; LYMPHOCYTE PROLIFERATION; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; SPLEEN CELL; UBIQUITINATION;

14-3-3 PROTEINS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; B-LYMPHOCYTES; BINDING SITES; DOWN-REGULATION; ENZYME ACTIVATION; HEK293 CELLS; HUMANS; MICE; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN-SERINE-THREONINE KINASES; PROTEOLYSIS; RECEPTORS, IMMUNOLOGIC; SIGNAL TRANSDUCTION; UBIQUITINATION;

EID: 84859514199     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.310946     Document Type: Article

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