PGE2 production is suppressed by chemically-synthesized δ7-eicosatrienoic acid in macrophages through the competitive inhibition of COX-2

Food and Chemical Toxicology

Volumn 66, Issue , 2014, Pages 122-133

  Huang, Wen Cheng ^a   Tsai, Po Jung ^a   Huang, Yu Lung ^b   Chen, Sung Nien ^b   Chuang, Lu Te ^b  

^a NATIONAL TAIWAN NORMAL UNIVERSITY   (Taiwan)

^b YUANPEI UNIVERSITY   (Taiwan)

Author keywords

7 Eicosatrienoic acid ( 7 ETrA); Arachidonic acid (AA); Macrophage; Prostaglandin E2 (PGE2); Type 2 cyclooxygenase (COX 2)

Indexed keywords

ARACHIDONIC ACID; CYCLOOXYGENASE 2; DELTA7 EICOSATRIENOIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; POLYUNSATURATED FATTY ACID; PROSTAGLANDIN E2; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG; CYCLOOXYGENASE 2 INHIBITOR; EICOSENOIC ACID; MONOUNSATURATED FATTY ACID; PHOSPHOLIPID;

ANIMAL CELL; ARTICLE; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; ENZYME ISOLATION; ENZYME REPRESSION; ENZYME SYNTHESIS; GAS CHROMATOGRAPHY; GENE TRANSLOCATION; IMMUNE RESPONSE; INCUBATION TIME; MACROPHAGE; MALE; MOUSE; NONHUMAN; PHOSPHOLIPID METABOLISM; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; ANIMAL; BIOSYNTHESIS; CELL LINE; DRUG EFFECTS; METABOLISM; SYNTHESIS;

ANIMALS; CELL LINE; CHROMATOGRAPHY, GAS; CYCLOOXYGENASE 2 INHIBITORS; DINOPROSTONE; FATTY ACIDS, MONOUNSATURATED; MACROPHAGES; MICE; PHOSPHOLIPIDS;

EID: 84896728085     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2014.01.031     Document Type: Article

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