메뉴 건너뛰기




Volumn 20, Issue 4, 2014, Pages 1042-1052

Overexpression of the circadian clock gene bmal1 increases sensitivity to oxaliplatin in colorectal cancer

Author keywords

[No Author keywords available]

Indexed keywords

CAPECITABINE; FLUOROURACIL; FOLINIC ACID; OXALIPLATIN; PROTEIN BMAL1;

EID: 84896727511     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-13-0171     Document Type: Article
Times cited : (123)

References (46)
  • 1
    • 0037194790 scopus 로고    scopus 로고
    • Coordination of circadian timing in mammals
    • Reppert SM, Weaver DR. Coordination of circadian timing in mammals. Nature 2002;418:935-41.
    • (2002) Nature , vol.418 , pp. 935-941
    • Reppert, S.M.1    Weaver, D.R.2
  • 2
    • 0037118077 scopus 로고    scopus 로고
    • Circadian rhythms from flies to human
    • Panda S, Hogenesch JB, Kay SA. Circadian rhythms from flies to human. Nature 2002;417:329-35.
    • (2002) Nature , vol.417 , pp. 329-335
    • Panda, S.1    Hogenesch, J.B.2    Kay, S.A.3
  • 3
    • 80053102580 scopus 로고    scopus 로고
    • Disrupting the circadian clock: Gene-specific effects on aging, cancer, and other phenotypes
    • Yu EA, Weaver DR. Disrupting the circadian clock: gene-specific effects on aging, cancer, and other phenotypes. Aging 2011;3:479-93.
    • (2011) Aging , vol.3 , pp. 479-493
    • Yu, E.A.1    Weaver, D.R.2
  • 4
    • 78649687209 scopus 로고    scopus 로고
    • Circadian integration of metabolism and energetics
    • Bass J, Takahashi JS. Circadian integration of metabolism and energetics. Science 2010;330:1349-54.
    • (2010) Science , vol.330 , pp. 1349-1354
    • Bass, J.1    Takahashi, J.S.2
  • 5
    • 0031557692 scopus 로고    scopus 로고
    • CDNA cloning and tissue-specific expression of a novel basic helix-loop-helix/PAS protein (BMAL1) and identification of alternatively spliced variants with alternative translation initiation site usage
    • Ikeda M, Nomura M. cDNA cloning and tissue-specific expression of a novel basic helix-loop-helix/PAS protein (BMAL1) and identification of alternatively spliced variants with alternative translation initiation site usage. Biochem Biophys Res Commun 1997;233:258-64.
    • (1997) Biochem Biophys Res Commun , vol.233 , pp. 258-264
    • Ikeda, M.1    Nomura, M.2
  • 6
    • 0037020198 scopus 로고    scopus 로고
    • The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo
    • Fu L, Pelicano H, Liu J, Huang P, Lee C. The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo. Cell 2002;111:41-50.
    • (2002) Cell , vol.111 , pp. 41-50
    • Fu, L.1    Pelicano, H.2    Liu, J.3    Huang, P.4    Lee, C.5
  • 7
    • 79959366611 scopus 로고    scopus 로고
    • A molecular mechanism for circadian clock negative feedback
    • Duong HA, Robles MS, Knutti D, Weitz CJ. A molecular mechanism for circadian clock negative feedback. Science 2011;332:1436-9.
    • (2011) Science , vol.332 , pp. 1436-1439
    • Duong, H.A.1    Robles, M.S.2    Knutti, D.3    Weitz, C.J.4
  • 8
    • 82855169511 scopus 로고    scopus 로고
    • Circadian clock protein BMAL1 regulates cellular senescence in vivo
    • Khapre RV, Kondratova AA, Susova O, Kondratov RV. Circadian clock protein BMAL1 regulates cellular senescence in vivo. Cell Cycle 2011;10:4162-9.
    • (2011) Cell Cycle , vol.10 , pp. 4162-4169
    • Khapre, R.V.1    Kondratova, A.A.2    Susova, O.3    Kondratov, R.V.4
  • 9
    • 24744470282 scopus 로고    scopus 로고
    • Brain and muscle Arnt-like protein-1 (BMAL1), a component of the molecular clock, regulates adipogenesis
    • Shimba S, Ishii N, Ohta Y, Ohno T, Watabe Y, Hayashi M, et al. Brain and muscle Arnt-like protein-1 (BMAL1), a component of the molecular clock, regulates adipogenesis. Proc Natl Acad Sci U S A 2005;102: 12071-6.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 12071-12076
    • Shimba, S.1    Ishii, N.2    Ohta, Y.3    Ohno, T.4    Watabe, Y.5    Hayashi, M.6
  • 10
    • 33750867235 scopus 로고    scopus 로고
    • MOP3, a component of the molecular clock, regulates the development of B cells
    • Sun Y, Yang Z, Niu Z, Peng J, Li Q, Xiong W, et al. MOP3, a component of the molecular clock, regulates the development of B cells. Immunology 2006;119:451-60.
    • (2006) Immunology , vol.119 , pp. 451-460
    • Sun, Y.1    Yang, Z.2    Niu, Z.3    Peng, J.4    Li, Q.5    Xiong, W.6
  • 12
    • 80455143198 scopus 로고    scopus 로고
    • Loss of Bmal1 leads to uncoupling and impaired glucose-stimulated insulin secretion in beta-cells
    • Lee J, KimMS, Li R, Liu VY, Fu L, Moore DD, et al. Loss of Bmal1 leads to uncoupling and impaired glucose-stimulated insulin secretion in beta-cells. Islets 2011;3:381-8.
    • (2011) Islets , vol.3 , pp. 381-388
    • Lee, J.1    Kim, M.S.2    Li, R.3    Liu, V.Y.4    Fu, L.5    Moore, D.D.6
  • 13
    • 84863895758 scopus 로고    scopus 로고
    • Brain and muscle Arnt-like protein-1 (BMAL1) controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis
    • Geyfman M, Kumar V, Liu Q, Ruiz R, Gordon W, Espitia F, et al. Brain and muscle Arnt-like protein-1 (BMAL1) controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis. Proc Natl Acad Sci U S A 2012;109:11758-63.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 11758-11763
    • Geyfman, M.1    Kumar, V.2    Liu, Q.3    Ruiz, R.4    Gordon, W.5    Espitia, F.6
  • 14
    • 62849106294 scopus 로고    scopus 로고
    • A large scale shRNA barcode screen identifies the circadian clock component ARNTL as putative regulator of the p53 tumor suppressor pathway
    • Mullenders J, Fabius AW, Madiredjo M, Bernards R, Beijersbergen RL. A large scale shRNA barcode screen identifies the circadian clock component ARNTL as putative regulator of the p53 tumor suppressor pathway. PLoS ONE 2009;4:e4798.
    • (2009) PLoS ONE , vol.4
    • Mullenders, J.1    Fabius, A.W.2    Madiredjo, M.3    Bernards, R.4    Beijersbergen, R.L.5
  • 15
    • 41949123764 scopus 로고    scopus 로고
    • The circadian clock component BMAL1 is a critical regulator of p21WAF1/CIP1 expression and hepatocyte proliferation
    • Grechez-Cassiau A, Rayet B, Guillaumond F, Teboul M, Delaunay F. The circadian clock component BMAL1 is a critical regulator of p21WAF1/CIP1 expression and hepatocyte proliferation. J Biol Chem 2008;283:4535-42.
    • (2008) J Biol Chem , vol.283 , pp. 4535-4542
    • Grechez-Cassiau, A.1    Rayet, B.2    Guillaumond, F.3    Teboul, M.4    Delaunay, F.5
  • 17
    • 33645499082 scopus 로고    scopus 로고
    • Use of the spatial scan statistic to identify geographic variations in late stage colorectal cancer in California (United States)
    • Pollack LA, Gotway CA, Bates JH, Parikh-Patel A, Richards TB, Seeff LC, et al. Use of the spatial scan statistic to identify geographic variations in late stage colorectal cancer in California (United States). Cancer Causes Control 2006;17:449-57.
    • (2006) Cancer Causes Control , vol.17 , pp. 449-457
    • Pollack, L.A.1    Gotway, C.A.2    Bates, J.H.3    Parikh-Patel, A.4    Richards, T.B.5    Seeff, L.C.6
  • 18
    • 0344783805 scopus 로고    scopus 로고
    • Phase II trial of oxaliplatin as first-line chemotherapy in metastatic colorectal cancer patients. Digestive Group of French Federation of Cancer Centers
    • Becouarn Y, Ychou M, Ducreux M, Borel C, Bertheault-Cvitkovic F, Seitz JF, et al. Phase II trial of oxaliplatin as first-line chemotherapy in metastatic colorectal cancer patients. Digestive Group of French Federation of Cancer Centers. J Clin Oncol 1998;16:2739-44.
    • (1998) J Clin Oncol , vol.16 , pp. 2739-2744
    • Becouarn, Y.1    Ychou, M.2    Ducreux, M.3    Borel, C.4    Bertheault-Cvitkovic, F.5    Seitz, J.F.6
  • 19
    • 0033874892 scopus 로고    scopus 로고
    • Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer
    • de Gramont A, Figer A, Seymour M, Homerin M, Hmissi A, Cassidy J, et al. Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol 2000;18:2938-47.
    • (2000) J Clin Oncol , vol.18 , pp. 2938-2947
    • De Gramont, A.1    Figer, A.2    Seymour, M.3    Homerin, M.4    Hmissi, A.5    Cassidy, J.6
  • 20
    • 0041055512 scopus 로고    scopus 로고
    • Randomised multicentre trial of chronotherapy with oxaliplatin, fluorouracil, and folinic acid in metastatic colorectal cancer. International Organization for Cancer Chronotherapy
    • Levi F, Zidani R, Misset JL. Randomised multicentre trial of chronotherapy with oxaliplatin, fluorouracil, and folinic acid in metastatic colorectal cancer. International Organization for Cancer Chronotherapy. Lancet 1997;350:681-6.
    • (1997) Lancet , vol.350 , pp. 681-686
    • Levi, F.1    Zidani, R.2    Misset, J.L.3
  • 24
    • 66349134112 scopus 로고    scopus 로고
    • Circadian rhythm in rest and activity: A biological correlate of quality of life and a predictor of survival in patients with metastatic colorectal cancer
    • Innominato PF, Focan C, Gorlia T, Moreau T, Garufi C, Waterhouse J, et al. Circadian rhythm in rest and activity: a biological correlate of quality of life and a predictor of survival in patients with metastatic colorectal cancer. Cancer Res 2009;69:4700-7.
    • (2009) Cancer Res , vol.69 , pp. 4700-4707
    • Innominato, P.F.1    Focan, C.2    Gorlia, T.3    Moreau, T.4    Garufi, C.5    Waterhouse, J.6
  • 25
    • 84867087511 scopus 로고    scopus 로고
    • Prediction of overall survival through circadian rest-activity monitoring during chemotherapy for metastatic colorectal cancer
    • Innominato PF, Giacchetti S, Bjarnason GA, Focan C, Garufi C, Coudert B, et al. Prediction of overall survival through circadian rest-activity monitoring during chemotherapy for metastatic colorectal cancer. Int J Cancer 2012;131:2684-92.
    • (2012) Int J Cancer , vol.131 , pp. 2684-2692
    • Innominato, P.F.1    Giacchetti, S.2    Bjarnason, G.A.3    Focan, C.4    Garufi, C.5    Coudert, B.6
  • 26
    • 0036118368 scopus 로고    scopus 로고
    • Enumeration of the simian virus 40 early region elements necessary for human cell transformation
    • Hahn WC, Dessain SK, Brooks MW, King JE, Elenbaas B, Sabatini DM, et al. Enumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol Cell Biol 2002;22:2111-23.
    • (2002) Mol Cell Biol , vol.22 , pp. 2111-2123
    • Hahn, W.C.1    Dessain, S.K.2    Brooks, M.W.3    King, J.E.4    Elenbaas, B.5    Sabatini, D.M.6
  • 27
    • 84865448011 scopus 로고    scopus 로고
    • Prognostic relevance of melanomaantigen D1expression in colorectal carcinoma
    • Zeng ZL, Wu WJ, Yang J, Tang ZJ, Chen DL, Qiu MZ, et al. Prognostic relevance of melanomaantigen D1expression in colorectal carcinoma. J Transl Med 2012;10:181.
    • (2012) J Transl Med , vol.10 , pp. 181
    • Zeng, Z.L.1    Wu, W.J.2    Yang, J.3    Tang, Z.J.4    Chen, D.L.5    Qiu, M.Z.6
  • 28
    • 34347233480 scopus 로고    scopus 로고
    • Mel-18 acts as a tumor suppressor by repressing Bmi-1 expression and downregulating Akt activity in breast cancer cells
    • Guo WJ, Zeng MS, Yadav A, Song LB, Guo BH, Band V, et al. Mel-18 acts as a tumor suppressor by repressing Bmi-1 expression and downregulating Akt activity in breast cancer cells. Cancer Res 2007;67: 5083-9.
    • (2007) Cancer Res , vol.67 , pp. 5083-5089
    • Guo, W.J.1    Zeng, M.S.2    Yadav, A.3    Song, L.B.4    Guo, B.H.5    Band, V.6
  • 29
    • 63149167365 scopus 로고    scopus 로고
    • Sphingosine kinase 1 is associated with gastric cancer progression and poor survival of patients
    • Li W, Yu CP, Xia JT, Zhang L, Weng GX, Zheng HQ, et al. Sphingosine kinase 1 is associated with gastric cancer progression and poor survival of patients. Clin Cancer Res 2009;15:1393-9.
    • (2009) Clin Cancer Res , vol.15 , pp. 1393-1399
    • Li, W.1    Yu, C.P.2    Xia, J.T.3    Zhang, L.4    Weng, G.X.5    Zheng, H.Q.6
  • 30
    • 28544444116 scopus 로고    scopus 로고
    • Synergistic effect of targeting mTOR by rapamycin and depleting ATP by inhibition of glycolysis in lymphoma and leukemia cells
    • Xu RH, Pelicano H, Zhang H, Giles FJ, Keating MJ, Huang P. Synergistic effect of targeting mTOR by rapamycin and depleting ATP by inhibition of glycolysis in lymphoma and leukemia cells. Leukemia 2005;19:2153-8.
    • (2005) Leukemia , vol.19 , pp. 2153-2158
    • Xu, R.H.1    Pelicano, H.2    Zhang, H.3    Giles, F.J.4    Keating, M.J.5    Huang, P.6
  • 31
    • 84864452759 scopus 로고    scopus 로고
    • Overexpression of GOLPH3 promotes proliferation and tumorigenicity in breast cancer via suppression of the FOXO1 transcription factor
    • Zeng Z, Lin H, Zhao X, Liu G, Wang X, Xu R, et al. Overexpression of GOLPH3 promotes proliferation and tumorigenicity in breast cancer via suppression of the FOXO1 transcription factor. Clin Cancer Res 2012;18:4059-69.
    • (2012) Clin Cancer Res , vol.18 , pp. 4059-4069
    • Zeng, Z.1    Lin, H.2    Zhao, X.3    Liu, G.4    Wang, X.5    Xu, R.6
  • 32
    • 14744278784 scopus 로고    scopus 로고
    • Circadian sensitivity to the chemotherapeutic agent cyclophosphamide depends on the functional status of the CLOCK/BMAL1 transactivation complex
    • Gorbacheva VY, Kondratov RV, Zhang R, Cherukuri S, Gudkov AV, Takahashi JS, et al. Circadian sensitivity to the chemotherapeutic agent cyclophosphamide depends on the functional status of the CLOCK/BMAL1 transactivation complex. Proc Natl Acad Sci U S A 2005;102:3407-12.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 3407-3412
    • Gorbacheva, V.Y.1    Kondratov, R.V.2    Zhang, R.3    Cherukuri, S.4    Gudkov, A.V.5    Takahashi, J.S.6
  • 33
    • 77956426309 scopus 로고    scopus 로고
    • Effects of the biological clock gene Bmal1 on tumour growth and anti-cancer drug activity
    • Zeng ZL,WuMW, Sun J, Sun YL, Cai YC, Huang YJ, et al. Effects of the biological clock gene Bmal1 on tumour growth and anti-cancer drug activity. J Biochem 2010;148:319-26.
    • (2010) J Biochem , vol.148 , pp. 319-326
    • Zeng, Z.L.1    Wu, M.W.2    Sun, J.3    Sun, Y.L.4    Cai, Y.C.5    Huang, Y.J.6
  • 34
    • 33847075354 scopus 로고    scopus 로고
    • Circadian rhythms: Mechanisms and therapeutic implications
    • Levi F, Schibler U. Circadian rhythms: mechanisms and therapeutic implications. Annu Rev Pharmacol Toxicol 2007;47:593-628.
    • (2007) Annu Rev Pharmacol Toxicol , vol.47 , pp. 593-628
    • Levi, F.1    Schibler, U.2
  • 35
    • 0037711399 scopus 로고    scopus 로고
    • The circadian clock: Pacemaker and tumour suppressor
    • Fu L, Lee CC. The circadian clock: pacemaker and tumour suppressor. Nat Rev Cancer 2003;3:350-61.
    • (2003) Nat Rev Cancer , vol.3 , pp. 350-361
    • Fu, L.1    Lee, C.C.2
  • 36
    • 0141889955 scopus 로고    scopus 로고
    • Control mechanism of the circadian clock for timing of cell division in vivo
    • Matsuo T, Yamaguchi S, Mitsui S, Emi A, Shimoda F, Okamura H. Control mechanism of the circadian clock for timing of cell division in vivo. Science 2003;302:255-9.
    • (2003) Science , vol.302 , pp. 255-259
    • Matsuo, T.1    Yamaguchi, S.2    Mitsui, S.3    Emi, A.4    Shimoda, F.5    Okamura, H.6
  • 37
    • 36949026694 scopus 로고    scopus 로고
    • Activation and regulation of ATM kinase activity in response to DNA double-strand breaks
    • Lee JH, Paull TT. Activation and regulation of ATM kinase activity in response to DNA double-strand breaks. Oncogene 2007;26:7741-8.
    • (2007) Oncogene , vol.26 , pp. 7741-7748
    • Lee, J.H.1    Paull, T.T.2
  • 39
    • 77449084056 scopus 로고    scopus 로고
    • Mammalian TIMELESS is required for ATM-dependent CHK2 activation and G2/M checkpoint control
    • Yang X, Wood PA, Hrushesky WJ. Mammalian TIMELESS is required for ATM-dependent CHK2 activation and G2/M checkpoint control. J Biol Chem 2010;285:3030-4.
    • (2010) J Biol Chem , vol.285 , pp. 3030-3034
    • Yang, X.1    Wood, P.A.2    Hrushesky, W.J.3
  • 40
    • 34447555674 scopus 로고    scopus 로고
    • Tumor suppression and circadian function
    • Chen-Goodspeed M, Lee CC. Tumor suppression and circadian function. J Biol Rhythms 2007;22:291-8.
    • (2007) J Biol Rhythms , vol.22 , pp. 291-298
    • Chen-Goodspeed, M.1    Lee, C.C.2
  • 41
    • 33646084831 scopus 로고    scopus 로고
    • The circadian gene per1 plays an important role in cell growth and DNA damage control in human cancer cells
    • Gery S, Komatsu N, Baldjyan L, Yu A, Koo D, Koeffler HP. The circadian gene per1 plays an important role in cell growth and DNA damage control in human cancer cells. Mol Cell 2006;22:375-82.
    • (2006) Mol Cell , vol.22 , pp. 375-382
    • Gery, S.1    Komatsu, N.2    Baldjyan, L.3    Yu, A.4    Koo, D.5    Koeffler, H.P.6
  • 43
    • 0037128686 scopus 로고    scopus 로고
    • Circadian optimisation of irinotecan and oxaliplatin efficacy in mice with Glasgow osteosarcoma
    • Granda TG, D'Attino RM, Filipski E, Vrignaud P, Garufi C, Terzoli E, et al. Circadian optimisation of irinotecan and oxaliplatin efficacy in mice with Glasgow osteosarcoma. Br J Cancer 2002;86:999-1005.
    • (2002) Br J Cancer , vol.86 , pp. 999-1005
    • Granda, T.G.1    D'Attino, R.M.2    Filipski, E.3    Vrignaud, P.4    Garufi, C.5    Terzoli, E.6
  • 44
    • 81255140206 scopus 로고    scopus 로고
    • Clock gene expression levels and relationship with clinical and pathological features in colorectal cancer patients
    • Mazzoccoli G, Panza A, Valvano MR, Palumbo O, Carella M, Pazienza V, et al. Clock gene expression levels and relationship with clinical and pathological features in colorectal cancer patients. Chronobiol Int 2011;28:841-51.
    • (2011) Chronobiol Int , vol.28 , pp. 841-851
    • Mazzoccoli, G.1    Panza, A.2    Valvano, M.R.3    Palumbo, O.4    Carella, M.5    Pazienza, V.6
  • 45
    • 79953050613 scopus 로고    scopus 로고
    • Expression of circadian genes correlates with liver metastasis and outcomes in colorectal cancer
    • Oshima T, Takenoshita S, Akaike M, Kunisaki C, Fujii S, Nozaki A, et al. Expression of circadian genes correlates with liver metastasis and outcomes in colorectal cancer. Oncol Rep 2011;25:1439-46.
    • (2011) Oncol Rep , vol.25 , pp. 1439-1446
    • Oshima, T.1    Takenoshita, S.2    Akaike, M.3    Kunisaki, C.4    Fujii, S.5    Nozaki, A.6
  • 46
    • 84867882294 scopus 로고    scopus 로고
    • The circadian clock gene BMAL1 is a novel therapeutic target for malignant pleural mesothelioma
    • Elshazley M, Sato M, Hase T, Yamashita R, Yoshida K, Toyokuni S, et al. The circadian clock gene BMAL1 is a novel therapeutic target for malignant pleural mesothelioma. Int J Cancer 2012;131:2820-31.
    • (2012) Int J Cancer , vol.131 , pp. 2820-2831
    • Elshazley, M.1    Sato, M.2    Hase, T.3    Yamashita, R.4    Yoshida, K.5    Toyokuni, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.