메뉴 건너뛰기




Volumn 51, Issue 1, 2014, Pages 123-131

The inflammatory status score including IL-6, TNF-α, osteopontin, fractalkine, MCP-1 and adiponectin underlies whole-body insulin resistance and hyperglycemia in type 2 diabetes mellitus

Author keywords

Adiponectin; Disposition index; Euglycemic hyperinsulinemic clamp; Fractalkine; Glucose metabolism; IL 6; Inflammation; MCP 1; Osteopontin; TNF ; Type 2 diabetes mellitus; Whole body insulin sensitivity

Indexed keywords

ADIPONECTIN; FRACTALKINE; GLUCOSE; HEMOGLOBIN A1C; INSULIN; INTERLEUKIN 6; METFORMIN; MONOCYTE CHEMOTACTIC PROTEIN 1; OSTEOPONTIN; SULFONYLUREA; TUMOR NECROSIS FACTOR ALPHA;

EID: 84896727271     PISSN: 09405429     EISSN: 14325233     Source Type: Journal    
DOI: 10.1007/s00592-013-0543-1     Document Type: Article
Times cited : (222)

References (44)
  • 3
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • 1:CAS:528:DC%2BD28XhtlShtrzK 17167474 10.1038/nature05485
    • Hotamisligil GS (2006) Inflammation and metabolic disorders. Nature 444(7121):860-867
    • (2006) Nature , vol.444 , Issue.7121 , pp. 860-867
    • Hotamisligil, G.S.1
  • 4
    • 0348230958 scopus 로고    scopus 로고
    • Obesity is associated with macrophage accumulation in adipose tissue
    • 1:CAS:528:DC%2BD3sXhtVSmtLvO 296995 14679176 10.1172/JCI200319246
    • Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr (2003) Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 112(12):1796-1808
    • (2003) J Clin Invest , vol.112 , Issue.12 , pp. 1796-1808
    • Weisberg, S.P.1    McCann, D.2    Desai, M.3    Rosenbaum, M.4    Leibel, R.L.5    Ferrante, Jr.A.W.6
  • 5
    • 9144223683 scopus 로고    scopus 로고
    • Chronic inflammation in fat plays a crucial role in the development of obesity related insulin resistance
    • 1:CAS:528:DC%2BD3sXhtVSmtLvI 296998 14679177 10.1172/JCI200319451
    • Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, Sole J, Nichols A, Ross JS, Tartaglia LA, Chen H (2003) Chronic inflammation in fat plays a crucial role in the development of obesity related insulin resistance. J Clin Invest 112(12):1821-1830
    • (2003) J Clin Invest , vol.112 , Issue.12 , pp. 1821-1830
    • Xu, H.1    Barnes, G.T.2    Yang, Q.3    Tan, G.4    Yang, D.5    Chou, C.J.6    Sole, J.7    Nichols, A.8    Ross, J.S.9    Tartaglia, L.A.10    Chen, H.11
  • 6
    • 23044463589 scopus 로고    scopus 로고
    • Circulating leptin correlates with left ventricular mass in morbid (grade III) obesity before and after weight loss induced by bariatric surgery: A potential role for leptin in mediating human left ventricular hypertrophy
    • 1:CAS:528:DC%2BD2MXmtlCitLg%3D 15855267 10.1210/jc.2004-1963
    • Perego L, Pizzocri P, Corradi D, Maisano F, Paganelli M, Fiorina P, Barbieri M, Morabito A, Paolisso G, Folli F, Pontiroli AE (2005) Circulating leptin correlates with left ventricular mass in morbid (grade III) obesity before and after weight loss induced by bariatric surgery: a potential role for leptin in mediating human left ventricular hypertrophy. J Clin Endocrinol Metab 90(7):4087-4093
    • (2005) J Clin Endocrinol Metab , vol.90 , Issue.7 , pp. 4087-4093
    • Perego, L.1    Pizzocri, P.2    Corradi, D.3    Maisano, F.4    Paganelli, M.5    Fiorina, P.6    Barbieri, M.7    Morabito, A.8    Paolisso, G.9    Folli, F.10    Pontiroli, A.E.11
  • 8
    • 33745216724 scopus 로고    scopus 로고
    • MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
    • 1:CAS:528:DC%2BD28XlsFWrtLo%3D 1459069 16691291 10.1172/JCI26498
    • Kanda H, Tateya S, Tamori Y, Kotani K, Hiasa K, Kitazawa R, Kitazawa S, Miyachi H, Maeda S, Egashira K, Kasuga M (2006) MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. J Clin Invest 116(6):1494-1505
    • (2006) J Clin Invest , vol.116 , Issue.6 , pp. 1494-1505
    • Kanda, H.1    Tateya, S.2    Tamori, Y.3    Kotani, K.4    Hiasa, K.5    Kitazawa, R.6    Kitazawa, S.7    Miyachi, H.8    Maeda, S.9    Egashira, K.10    Kasuga, M.11
  • 9
    • 33748099699 scopus 로고    scopus 로고
    • Circulating levels of MCP-1 and IL-8 are elevated in human obese subjects and associated with obesity-related parameters
    • 1:CAS:528:DC%2BD28XovVSqtbc%3D 10.1038/sj.ijo.0803259
    • Kim CS, Park HS, Kawada T, Kim JH, Lim D, Hubbard NE, Kwon BS, Erickson KL, Yu R (2006) Circulating levels of MCP-1 and IL-8 are elevated in human obese subjects and associated with obesity-related parameters. Int J Obes (Lond) 30(9):1347-1355
    • (2006) Int J Obes (Lond) , vol.30 , Issue.9 , pp. 1347-1355
    • Kim, C.S.1    Park, H.S.2    Kawada, T.3    Kim, J.H.4    Lim, D.5    Hubbard, N.E.6    Kwon, B.S.7    Erickson, K.L.8    Yu, R.9
  • 12
    • 34249031626 scopus 로고    scopus 로고
    • Osteopontin: A novel inflammatory mediator of cardiovascular disease
    • 1:CAS:528:DC%2BD28Xht1WgsLzJ 17127294 10.2741/2059
    • Singh M, Ananthula S, Milhorn DM, Krishnaswamy G, Singh K (2007) Osteopontin: a novel inflammatory mediator of cardiovascular disease. Front Biosci 12:214-221
    • (2007) Front Biosci , vol.12 , pp. 214-221
    • Singh, M.1    Ananthula, S.2    Milhorn, D.M.3    Krishnaswamy, G.4    Singh, K.5
  • 13
    • 79959427550 scopus 로고    scopus 로고
    • Fractalkine: A cellular link between adipose tissue inflammation and vascular pathologies
    • 1:CAS:528:DC%2BC3MXmsVKltb8%3D 21525509 10.2337/db11-0239
    • Cefalu WT (2011) Fractalkine: a cellular link between adipose tissue inflammation and vascular pathologies. Diabetes 60(5):1380-1382
    • (2011) Diabetes , vol.60 , Issue.5 , pp. 1380-1382
    • Cefalu, W.T.1
  • 15
  • 17
    • 84888203171 scopus 로고    scopus 로고
    • Type 2 diabetes mellitus an autoimmune disease?
    • 10.1038/nrendo.2013.131 23835371
    • Velloso LA, Eizirik DL, Cnop M (2013) Type 2 diabetes mellitus an autoimmune disease? Nat Rev Endocrinol. doi: 10.1038/nrendo.2013.131
    • (2013) Nat Rev Endocrinol
    • Velloso, L.A.1    Eizirik, D.L.2    Cnop, M.3
  • 21
    • 3042541843 scopus 로고    scopus 로고
    • Effects of short-term treatment with metformin on markers of endothelial function and inflammatory activity in type 2 diabetes mellitus: A randomized, placebo-controlled trial
    • 10.1111/j.1365-2796.2004.01328.x
    • De Jager J, Kooy A, Lehert P, Bets D, Wulffelé MG, Teerlink T, Scheffer PG, Schalkwijk CG, Donker AJ, Stehouwer CD (2004) Effects of short-term treatment with metformin on markers of endothelial function and inflammatory activity in type 2 diabetes mellitus: a randomized, placebo-controlled trial. J Intern Med 256:1-14
    • (2004) J Intern Med , vol.256 , pp. 1-14
    • De Jager, J.1    Kooy, A.2    Lehert, P.3    Bets, D.4    Wulffelé, M.G.5    Teerlink, T.6    Scheffer, P.G.7    Schalkwijk, C.G.8    Donker, A.J.9    Stehouwer, C.D.10
  • 22
    • 33646433464 scopus 로고    scopus 로고
    • Prevalence and correlates of post-prandial hyperglycaemia in a large sample of patients with type 2 diabetes mellitus
    • 1:STN:280:DC%2BD283jsVWiuw%3D%3D 16532323 10.1007/s00125-006-0203-x
    • Bonora E, Corrao G, Bagnardi V, Ceriello A, Comaschi M, Montanari P, Meigs JB (2006) Prevalence and correlates of post-prandial hyperglycaemia in a large sample of patients with type 2 diabetes mellitus. Diabetologia 49(5):846-854
    • (2006) Diabetologia , vol.49 , Issue.5 , pp. 846-854
    • Bonora, E.1    Corrao, G.2    Bagnardi, V.3    Ceriello, A.4    Comaschi, M.5    Montanari, P.6    Meigs, J.B.7
  • 23
    • 0037109184 scopus 로고    scopus 로고
    • Inflammatory cytokine concentrations are acutely increased by hyperglycemia in humans: Role of oxidative stress
    • 1:CAS:528:DC%2BD38Xns1SnsL4%3D 12379575 10.1161/01.CIR.0000034509.14906. AE
    • Esposito K, Nappo F, Marfella R, Giugliano G, Giugliano F, Ciotola M, Quagliaro L, Ceriello A, Giugliano D (2002) Inflammatory cytokine concentrations are acutely increased by hyperglycemia in humans: role of oxidative stress. Circulation 106:2067-2072
    • (2002) Circulation , vol.106 , pp. 2067-2072
    • Esposito, K.1    Nappo, F.2    Marfella, R.3    Giugliano, G.4    Giugliano, F.5    Ciotola, M.6    Quagliaro, L.7    Ceriello, A.8    Giugliano, D.9
  • 24
    • 33845499326 scopus 로고    scopus 로고
    • Changes in inflammatory cytokines are related to impaired glucose tolerance in offspring of type 2 diabetic subjects
    • 1:CAS:528:DC%2BD2sXhtVGgsQ%3D%3D 17130210 10.2337/dc06-0147
    • Ruotsalainen E, Salmenniemi U, Vauhkonen I, Pihlajamäki J, Punnonen K, Kainulainen S, Laakso M (2006) Changes in inflammatory cytokines are related to impaired glucose tolerance in offspring of type 2 diabetic subjects. Diabetes Care 29(12):2714-2720
    • (2006) Diabetes Care , vol.29 , Issue.12 , pp. 2714-2720
    • Ruotsalainen, E.1    Salmenniemi, U.2    Vauhkonen, I.3    Pihlajamäki, J.4    Punnonen, K.5    Kainulainen, S.6    Laakso, M.7
  • 25
    • 39449139083 scopus 로고    scopus 로고
    • Markers of endothelial dysfunction and low-grade inflammation are associated in the offspring of type 2 diabetic subjects
    • 1:CAS:528:DC%2BD1cXisVSls7w%3D 17560580 10.1016/j.atherosclerosis.2007. 04.021
    • Ruotsalainen E, Vauhkonen I, Salmenniemi U, Pihlajamäki J, Punnonen K, Kainulainen S, Jalkanen S, Salmi M, Laakso M (2008) Markers of endothelial dysfunction and low-grade inflammation are associated in the offspring of type 2 diabetic subjects. Atherosclerosis 197(1):271-277
    • (2008) Atherosclerosis , vol.197 , Issue.1 , pp. 271-277
    • Ruotsalainen, E.1    Vauhkonen, I.2    Salmenniemi, U.3    Pihlajamäki, J.4    Punnonen, K.5    Kainulainen, S.6    Jalkanen, S.7    Salmi, M.8    Laakso, M.9
  • 26
    • 84875054251 scopus 로고    scopus 로고
    • Decreased carotid atherosclerotic process by control of daily acute glucose fluctuations in diabetic patients treated by DPP-IV inhibitors
    • 1:CAS:528:DC%2BC3sXhvFWrurs%3D 23375680 10.1016/j.atherosclerosis.2012. 12.018
    • Barbieri M, Rizzo MR, Marfella R, Boccardi V, Esposito A, Pansini A, Paolisso G (2013) Decreased carotid atherosclerotic process by control of daily acute glucose fluctuations in diabetic patients treated by DPP-IV inhibitors. Atherosclerosis 227(2):349-354
    • (2013) Atherosclerosis , vol.227 , Issue.2 , pp. 349-354
    • Barbieri, M.1    Rizzo, M.R.2    Marfella, R.3    Boccardi, V.4    Esposito, A.5    Pansini, A.6    Paolisso, G.7
  • 27
    • 0032735973 scopus 로고    scopus 로고
    • Insulin resistance and inflammation in an evolutionary perspective: The contribution of cytokine genotype/phenotype to thriftiness
    • 1:CAS:528:DyaK1MXmvF2msL0%3D 10550422 10.1007/s001250051451
    • Fernandez-Real JM, Ricart W (1999) Insulin resistance and inflammation in an evolutionary perspective: the contribution of cytokine genotype/phenotype to thriftiness. Diabetologia 42:1367-1374
    • (1999) Diabetologia , vol.42 , pp. 1367-1374
    • Fernandez-Real, J.M.1    Ricart, W.2
  • 28
    • 40949109757 scopus 로고    scopus 로고
    • Increased skeletal muscle tumor necrosis factor alpha and impaired insulin signaling persist in obese women with gestational diabetes mellitus 1 year postpartum
    • 18083784 10.2337/db07-1356
    • Friedman JE, Kirwan JP, Jing M, Presley L, Catalano PM (2008) Increased skeletal muscle tumor necrosis factor alpha and impaired insulin signaling persist in obese women with gestational diabetes mellitus 1 year postpartum. Diabetes 57(3):606-613
    • (2008) Diabetes , vol.57 , Issue.3 , pp. 606-613
    • Friedman, J.E.1    Kirwan, J.P.2    Jing, M.3    Presley, L.4    Catalano, P.M.5
  • 29
    • 84861696510 scopus 로고    scopus 로고
    • Lack of association of apoE ε4 allele with insulin resistance
    • 1:CAS:528:DC%2BC38XhsV2qsrY%3D 21290252 10.1007/s00592-011-0255-3
    • Ragogna F, Lattuada G, Ruotolo G, Luzi L, Perseghin G (2012) Lack of association of apoE ε4 allele with insulin resistance. Acta Diabetol 49:25-32
    • (2012) Acta Diabetol , vol.49 , pp. 25-32
    • Ragogna, F.1    Lattuada, G.2    Ruotolo, G.3    Luzi, L.4    Perseghin, G.5
  • 30
    • 0028362194 scopus 로고
    • Tumor necrosis factor a inhibits signaling from the insulin receptor
    • 1:CAS:528:DyaK2cXktVOiurY%3D 8197147 10.1073/pnas.91.11.4854
    • Hotamisligil GS, Murray DL, Choy LN, Spiegelman BM (1994) Tumor necrosis factor a inhibits signaling from the insulin receptor. Proc Natl Acad Sci USA 91:4854-4858
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4854-4858
    • Hotamisligil, G.S.1    Murray, D.L.2    Choy, L.N.3    Spiegelman, B.M.4
  • 34
    • 0033821518 scopus 로고    scopus 로고
    • The influence of improved glycaemic control with insulin and sulphonylureas on acute phase and endothelial markers in type II diabetic subjects
    • 1:CAS:528:DC%2BD3cXnt1OltLs%3D 11043855 10.1007/s001250051500
    • Yudkin JS, Panahloo A, Stehouwer C, Emeis JJ, Bulmer K, Mohamed-Ali V, Denver AE (2000) The influence of improved glycaemic control with insulin and sulphonylureas on acute phase and endothelial markers in type II diabetic subjects. Diabetologia 43:1099-1106
    • (2000) Diabetologia , vol.43 , pp. 1099-1106
    • Yudkin, J.S.1    Panahloo, A.2    Stehouwer, C.3    Emeis, J.J.4    Bulmer, K.5    Mohamed-Ali, V.6    Denver, A.E.7
  • 35
    • 84855678225 scopus 로고    scopus 로고
    • Validation of a novel index to assess insulin resistance of adipose tissue lipolytic activity in obese subjects
    • 1:CAS:528:DC%2BC38XpvFygsg%3D%3D 22147838 10.1194/jlr.D020321
    • Fabbrini E, Magkos F, Conte C, Mittendorfer B, Patterson BW, Okunade AL, Klein S (2012) Validation of a novel index to assess insulin resistance of adipose tissue lipolytic activity in obese subjects. J Lipid Res 53(2):321-324
    • (2012) J Lipid Res , vol.53 , Issue.2 , pp. 321-324
    • Fabbrini, E.1    Magkos, F.2    Conte, C.3    Mittendorfer, B.4    Patterson, B.W.5    Okunade, A.L.6    Klein, S.7
  • 37
    • 75649096002 scopus 로고    scopus 로고
    • Thioredoxin-interacting protein links oxidative stress to inflammasome activation
    • 1:CAS:528:DC%2BD1MXhsFyhsLrJ 20023662 10.1038/ni.1831
    • Zhou R, Tardivel A, Thorens B, Choi I, Tschopp J (2010) Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat Immunol 11:136-140
    • (2010) Nat Immunol , vol.11 , pp. 136-140
    • Zhou, R.1    Tardivel, A.2    Thorens, B.3    Choi, I.4    Tschopp, J.5
  • 38
    • 70349859675 scopus 로고    scopus 로고
    • Multiple levels of regulation determine the role of the receptor for AGE (RAGE) as common soil in inflammation, immune responses and diabetes mellitus and its complications
    • 1:CAS:528:DC%2BD1MXht1Cis7jE 19636529 10.1007/s00125-009-1458-9
    • Bierhaus A, Nawroth PP (2009) Multiple levels of regulation determine the role of the receptor for AGE (RAGE) as common soil in inflammation, immune responses and diabetes mellitus and its complications. Diabetologia 52(11):2251-2263
    • (2009) Diabetologia , vol.52 , Issue.11 , pp. 2251-2263
    • Bierhaus, A.1    Nawroth, P.P.2
  • 40
    • 0034881391 scopus 로고    scopus 로고
    • The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
    • 1:CAS:528:DC%2BD3MXlvVOktLw%3D 11479628 10.1038/90992
    • Berg AH, Combs TP, Du X, Brownlee M, Scherer PE (2001) The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat Med 7:947-953
    • (2001) Nat Med , vol.7 , pp. 947-953
    • Berg, A.H.1    Combs, T.P.2    Du, X.3    Brownlee, M.4    Scherer, P.E.5
  • 44
    • 84864285795 scopus 로고    scopus 로고
    • Management of hyperglycaemia in type 2 diabetes: A patient-centered approach: Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
    • 1:STN:280:DC%2BC38rnsV2jsA%3D%3D 22526604 10.1007/s00125-012-2534-0
    • Inzucchi SE, Bergenstal RM, Buse JB, Diamant M, Ferrannini E, Nauck M, Peters AL, Tsapas A, Wender R, Matthews DR (2012) Management of hyperglycaemia in type 2 diabetes: a patient-centered approach: position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetologia 55(6):1577-1596
    • (2012) Diabetologia , vol.55 , Issue.6 , pp. 1577-1596
    • Inzucchi, S.E.1    Bergenstal, R.M.2    Buse, J.B.3    Diamant, M.4    Ferrannini, E.5    Nauck, M.6    Peters, A.L.7    Tsapas, A.8    Wender, R.9    Matthews, D.R.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.