P16INK4A immunostaining is a strong indicator for high-risk-HPV-associated oropharyngeal carcinomas and dysplasias, but is unreliable to predict low-risk-HPV-infection in head and neck papillomas and laryngeal dysplasias

International Journal of Cancer

Volumn 134, Issue 9, 2014, Pages 2108-2117

  Mooren, Jeroen J ^a   Gültekin, Sibel E ^b   Straetmans, Jos M J A A ^a   Haesevoets, Annick ^a   Peutz Kootstra, Carine J ^a   Huebbers, Christian U ^c   Dienes, Hans P ^c   Wieland, Ulrike ^c   Ramaekers, Frans C S ^a   Kremer, Bernd ^a   Speel, Ernst Jan M ^a   Klussmann, Jens P ^d  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b GAZI UNIVERSITY   (Turkey)

^c UNIVERSITY OF COLOGNE   (Germany)

^d JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

FISH; human papillomavirus; immunohistochemistry; PCR

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A;

ADULT; AGED; ARTICLE; CANCER RISK; CELL NUCLEUS; CONTROLLED STUDY; CORRELATIONAL STUDY; CYTOPLASM; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; DYSPLASIA; ENZYME IMMUNOASSAY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HIGH RISK POPULATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFECTION RISK; LARYNGEAL DYSPLASIA; LARYNX PAPILLOMATOSIS; LOW RISK POPULATION; MAJOR CLINICAL STUDY; MALE; OROPHARYNX CARCINOMA; PAPILLOMA; PAPILLOMAVIRUS INFECTION; POLYMERASE CHAIN REACTION; PRECANCER; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TONSILLAR DYSPLASIA; TONSILLAR PAPILLOMA;

FISH; HUMAN PAPILLOMAVIRUS; IMMUNOHISTOCHEMISTRY; PCR;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; CHILD; CHILD, PRESCHOOL; CYCLIN-DEPENDENT KINASE INHIBITOR P16; FEMALE; HEAD AND NECK NEOPLASMS; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; INFANT; LARYNGEAL NEOPLASMS; MALE; MIDDLE AGED; OROPHARYNGEAL NEOPLASMS; PAPILLOMA; PAPILLOMAVIRUS INFECTIONS; PRECANCEROUS CONDITIONS; RISK FACTORS; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT;

EID: 84896726083     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.28534     Document Type: Article

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