Microenvironmental Variables Must Influence Intrinsic Phenotypic Parameters of Cancer Stem Cells to Affect Tumourigenicity

PLoS Computational Biology

Volumn 10, Issue 1, 2014, Pages

  Scott, Jacob G ^a,b   Hjelmeland, Anita B ^c   Chinnaiyan, Prakash ^a   Anderson, Alexander R A ^a   Basanta, David ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOLOGY; DISEASES; STEM CELLS;

CANCER STEM CELLS; CELL DRIVEN; CELLULAR AUTOMATA MODELS; DISCRETE/CONTINUOUS; MICROENVIRONMENTS; PHENOTYPIC TRAITS; SIMPLE++; SOLID TUMORS; STEM-CELL; TISSUE GROWTH;

TUMORS;

ARTICLE; AUTOMATION; CANCER GROWTH; CANCER STEM CELL; CARCINOGENICITY; CELL COMPOSITION; CELL DIVISION; CONTROLLED STUDY; DYNAMICS; HOMEOSTASIS; LIFESPAN; MATHEMATICAL MODEL; PHENOTYPE; TISSUE GROWTH; TUMOR INITIATING CELL; TUMOR MICROENVIRONMENT; TUMOR VASCULARIZATION;

ALGORITHMS; BRAIN; CELL HYPOXIA; CELL TRANSFORMATION, NEOPLASTIC; COMPUTER SIMULATION; DISEASE PROGRESSION; HUMANS; MODELS, BIOLOGICAL; MUTATION; NEOPLASMS; NEOPLASTIC STEM CELLS; PHENOTYPE; TUMOR MICROENVIRONMENT;

EID: 84896725683     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1003433     Document Type: Article

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