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Volumn 7, Issue , 2014, Pages 33-42

Genetics of bipolar disorder

Author keywords

Bipolar disorder; Genetic testing; Genomic variants; Mendelian disorders; Risk factors; Structural variants

Indexed keywords

CALCIUM CHANNEL L TYPE; MEMBRANE PROTEIN; NEUROCAN; PROTEIN CACNA1C; PROTEIN ODZ4; UNCLASSIFIED DRUG;

EID: 84896719748     PISSN: None     EISSN: 1178704X     Source Type: Journal    
DOI: 10.2147/TACG.S39297     Document Type: Review
Times cited : (98)

References (105)
  • 1
    • 84896704509 scopus 로고    scopus 로고
    • National Institute of Mental Health. Bipolar disorder among adults. Available from, Accessed January 10, 2014
    • National Institute of Mental Health. Bipolar disorder among adults. Available from: http://www.nimh.nih.gov/statistics/1bipolar_adult.shtml. Accessed January 10, 2014.
  • 2
    • 84896737729 scopus 로고    scopus 로고
    • American Psychiatric Association [homepage on the internet]. Available from, Accessed January 10, 2014
    • American Psychiatric Association [homepage on the internet]. Available from: http://www.psychiatry.org/home. Accessed January 10, 2014.
  • 3
    • 84908143177 scopus 로고    scopus 로고
    • Independence of familial transmission of mania and depression: Results of the NIMH family study of affective spectrum disorders
    • Epub October 15
    • Merikangas KR, Cui L, Heaton L, et al. Independence of familial transmission of mania and depression: results of the NIMH family study of affective spectrum disorders. Mol Psychiatry. Epub October 15, 2013.
    • (2013) Mol Psychiatry
    • Merikangas, K.R.1    Cui, L.2    Heaton, L.3
  • 5
    • 84886717907 scopus 로고    scopus 로고
    • Anxiety, stress and perfectionism in bipolar disorder
    • Corry J, Green M, Roberts G, et al. Anxiety, stress and perfectionism in bipolar disorder. J Affect Disord. 2013;151(3):1016-1024.
    • (2013) J Affect Disord , vol.151 , Issue.3 , pp. 1016-1024
    • Corry, J.1    Green, M.2    Roberts, G.3
  • 6
    • 84890148892 scopus 로고    scopus 로고
    • Psychiatric comorbidity in treatment seeking substance use disorder patients with and without ADHD; results of the IASP study
    • Epub October 4
    • van Emmerik-van Oortmerssen K, van de Glind G, Koeter MW, et al. Psychiatric comorbidity in treatment seeking substance use disorder patients with and without ADHD; results of the IASP study. Addiction. Epub October 4, 2013.
    • (2013) Addiction
    • van Emmerik-van Oortmerssen, K.1    van de Glind, G.2    Koeter, M.W.3
  • 7
    • 84896735398 scopus 로고    scopus 로고
    • Alcohol misuse in bipolar disorder. A systematic review and meta-analysis of comorbidity rates
    • Epub September 25
    • Di Florio A, Craddock N, van den Bree M. Alcohol misuse in bipolar disorder. A systematic review and meta-analysis of comorbidity rates. Eur Psychiatry. Epub September 25, 2013.
    • (2013) Eur Psychiatry
    • Di Florio, A.1    Craddock, N.2    van den Bree, M.3
  • 8
    • 84904815853 scopus 로고    scopus 로고
    • Adult attention-deficit/hyperactivity disorder in major depressed and bipolar subjects: Role of personality traits and clinical implications
    • Epub September 28
    • Di Nicola M, Sala L, Romo L, et al. Adult attention-deficit/hyperactivity disorder in major depressed and bipolar subjects: role of personality traits and clinical implications. Eur Arch Psychiatry Clin Neurosci. Epub September 28, 2013.
    • (2013) Eur Arch Psychiatry Clin Neurosci
    • Di Nicola, M.1    Sala, L.2    Romo, L.3
  • 9
    • 78650472671 scopus 로고    scopus 로고
    • Bipolar disorder: New perspectives in health care and prevention
    • Leboyer M, Kupfer DJ. Bipolar disorder: new perspectives in health care and prevention. J Clin Psychiatry. 2010;71(12):1689-1695.
    • (2010) J Clin Psychiatry , vol.71 , Issue.12 , pp. 1689-1695
    • Leboyer, M.1    Kupfer, D.J.2
  • 11
    • 84886558492 scopus 로고    scopus 로고
    • Suicidal ideation and suicide attempts in children and adolescents with bipolar disorder: A systematic review of prevalence and incidence rates, correlates, and targeted interventions
    • Hauser M, Galling B, Correll CU. Suicidal ideation and suicide attempts in children and adolescents with bipolar disorder: a systematic review of prevalence and incidence rates, correlates, and targeted interventions. Bipolar Disord. 2013;15(5):507-523.
    • (2013) Bipolar Disord , vol.15 , Issue.5 , pp. 507-523
    • Hauser, M.1    Galling, B.2    Correll, C.U.3
  • 12
    • 77955287190 scopus 로고    scopus 로고
    • Early-onset bipolar disorder and treatment delay are risk factors for poor outcome in adulthood
    • Post RM, Leverich GS, Kupka RW, et al. Early-onset bipolar disorder and treatment delay are risk factors for poor outcome in adulthood. J Clin Psychiatry. 2010;71(7):864-872.
    • (2010) J Clin Psychiatry , vol.71 , Issue.7 , pp. 864-872
    • Post, R.M.1    Leverich, G.S.2    Kupka, R.W.3
  • 13
    • 0242354132 scopus 로고    scopus 로고
    • Family, twin, and adoption studies of bipolar disorder
    • Smoller JW, Finn CT. Family, twin, and adoption studies of bipolar disorder. Am J Med Genet C Semin Med Genet. 2003;123C(1):48-58.
    • (2003) Am J Med Genet C Semin Med Genet , vol.123 C , Issue.1 , pp. 48-58
    • Smoller, J.W.1    Finn, C.T.2
  • 14
    • 84869025817 scopus 로고    scopus 로고
    • Using summary data from the Danish national registers to estimate heritabilities for schizophrenia, bipolar disorder, and major depressive disorder
    • Wray NR, Gottesman II. Using summary data from the Danish national registers to estimate heritabilities for schizophrenia, bipolar disorder, and major depressive disorder. Front Genet. 2012;3:118.
    • (2012) Front Genet , vol.3 , pp. 118
    • Wray, N.R.1    Gottesman, I.I.2
  • 15
    • 84896695704 scopus 로고    scopus 로고
    • Additive effects of childhood abuse and cannabis abuse on clinical expressions of bipolar disorders
    • Epub September 13
    • Aas M, Etain B, Bellivier F, et al. Additive effects of childhood abuse and cannabis abuse on clinical expressions of bipolar disorders. Psychol Med. Epub September 13, 2013.
    • (2013) Psychol Med
    • Aas, M.1    Etain, B.2    Bellivier, F.3
  • 16
    • 78249256348 scopus 로고    scopus 로고
    • The environment and susceptibility to schizophrenia
    • Brown AS. The environment and susceptibility to schizophrenia. Prog Neurobiol. 2011;93(1):23-58.
    • (2011) Prog Neurobiol , vol.93 , Issue.1 , pp. 23-58
    • Brown, A.S.1
  • 18
    • 84871436061 scopus 로고    scopus 로고
    • Prenatal infection, maternal immune activation, and risk for schizophrenia
    • Canetta SE, Brown AS. Prenatal infection, maternal immune activation, and risk for schizophrenia. Transl Neurosci. 2012;3(4):320-327.
    • (2012) Transl Neurosci , vol.3 , Issue.4 , pp. 320-327
    • Canetta, S.E.1    Brown, A.S.2
  • 19
    • 84872118489 scopus 로고    scopus 로고
    • Prenatal maternal infection, neurodevelopment and adult schizophrenia: A systematic review of population-based studies
    • Khandaker GM, Zimbron J, Lewis G, Jones PB. Prenatal maternal infection, neurodevelopment and adult schizophrenia: a systematic review of population-based studies. Psychol Med. 2013;43(2): 239-257.
    • (2013) Psychol Med , vol.43 , Issue.2 , pp. 239-257
    • Khandaker, G.M.1    Zimbron, J.2    Lewis, G.3    Jones, P.B.4
  • 20
    • 84894351277 scopus 로고    scopus 로고
    • Pre- and perinatal hypoxia associated with hippocampus/amygdala volume in bipolar disorder
    • Haukvik UK, McNeil T, Lange EH, et al. Pre- and perinatal hypoxia associated with hippocampus/amygdala volume in bipolar disorder. Psychol Med. 2013;27:1-11.
    • (2013) Psychol Med , vol.27 , pp. 1-11
    • Haukvik, U.K.1    McNeil, T.2    Lange, E.H.3
  • 21
    • 84905006739 scopus 로고    scopus 로고
    • Excess of rare novel loss-of-function variants in synaptic genes in schizophrenia and autism spectrum disorders
    • Epub October 15
    • Kenny EM, Cormican P, Furlong S, et al. Excess of rare novel loss-of-function variants in synaptic genes in schizophrenia and autism spectrum disorders. Mol Psychiatry. Epub October 15, 2013.
    • (2013) Mol Psychiatry
    • Kenny, E.M.1    Cormican, P.2    Furlong, S.3
  • 22
    • 84877704720 scopus 로고    scopus 로고
    • Genetics of bipolar disorder
    • Craddock N, Sklar P. Genetics of bipolar disorder. Lancet. 2013;381(9878):1654-1662.
    • (2013) Lancet , vol.381 , Issue.9878 , pp. 1654-1662
    • Craddock, N.1    Sklar, P.2
  • 23
    • 84885918812 scopus 로고    scopus 로고
    • Evidence for single nucleotide polymorphisms and their association with bipolar disorder
    • Szczepankiewicz A. Evidence for single nucleotide polymorphisms and their association with bipolar disorder. Neuropsychiatr Dis Treat. 2013;9:1573-1582.
    • (2013) Neuropsychiatr Dis Treat , vol.9 , pp. 1573-1582
    • Szczepankiewicz, A.1
  • 24
    • 43949118134 scopus 로고    scopus 로고
    • Whole-genome association study of bipolar disorder
    • Sklar P, Smoller JW, Fan J, et al. Whole-genome association study of bipolar disorder. Mol Psychiatry. 2008;13(6):558-569.
    • (2008) Mol Psychiatry , vol.13 , Issue.6 , pp. 558-569
    • Sklar, P.1    Smoller, J.W.2    Fan, J.3
  • 25
    • 50449089356 scopus 로고    scopus 로고
    • Wellcome Trust Case Control Consortium. Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder
    • Ferreira MA, O'Donovan MC, Meng YA, et al. Wellcome Trust Case Control Consortium. Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet. 2008;40(9):1056-1058.
    • (2008) Nat Genet , vol.40 , Issue.9 , pp. 1056-1058
    • Ferreira, M.A.1    O'Donovan, M.C.2    Meng, Y.A.3
  • 26
    • 60549085927 scopus 로고    scopus 로고
    • Gene-wide analyses of genome-wide association data sets: Evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk
    • Moskvina V, Craddock N, Holmans P, et al. Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk. Mol Psychiatry. 2009;14(3):252-260.
    • (2009) Mol Psychiatry , vol.14 , Issue.3 , pp. 252-260
    • Moskvina, V.1    Craddock, N.2    Holmans, P.3
  • 27
    • 84863470133 scopus 로고    scopus 로고
    • ANK3 and CACNA1C: Missing genetic link for bipolar disorder and major depressive disorder in two German case-control samples
    • Kloiber S, Czamara D, Karbalai N, et al. ANK3 and CACNA1C: missing genetic link for bipolar disorder and major depressive disorder in two German case-control samples. J Psychiatr Res. 2012;46(8):973-979.
    • (2012) J Psychiatr Res , vol.46 , Issue.8 , pp. 973-979
    • Kloiber, S.1    Czamara, D.2    Karbalai, N.3
  • 28
    • 84885178774 scopus 로고    scopus 로고
    • Does the bipolar disorder-associated CACNA1C gene confer susceptibility to schizophrenia in Han Chinese?
    • Zhang J, Cai J, Zhang X, et al. Does the bipolar disorder-associated CACNA1C gene confer susceptibility to schizophrenia in Han Chinese? J Mol Neurosci. 2013;51(2):474-477.
    • (2013) J Mol Neurosci , vol.51 , Issue.2 , pp. 474-477
    • Zhang, J.1    Cai, J.2    Zhang, X.3
  • 29
    • 84882881289 scopus 로고    scopus 로고
    • Association of genetic variation in CACNA1C with bipolar disorder in Han Chinese
    • Zhang X, Zhang C, Wu Z, et al. Association of genetic variation in CACNA1C with bipolar disorder in Han Chinese. J Affect Disord. 2013;150(2):261-265.
    • (2013) J Affect Disord , vol.150 , Issue.2 , pp. 261-265
    • Zhang, X.1    Zhang, C.2    Wu, Z.3
  • 30
    • 84905027678 scopus 로고    scopus 로고
    • A rare mutation of CACNA1C in a patient with bipolar disorder, and decreased gene expression associated with a bipolar-associated common SNP of CACNA1C in brain
    • Epub August 27
    • Gershon ES, Grennan K, Busnello J, et al. A rare mutation of CACNA1C in a patient with bipolar disorder, and decreased gene expression associated with a bipolar-associated common SNP of CACNA1C in brain. Mol Psychiatry. Epub August 27, 2013.
    • (2013) Mol Psychiatry
    • Gershon, E.S.1    Grennan, K.2    Busnello, J.3
  • 31
    • 77956359560 scopus 로고    scopus 로고
    • Genetic variation in CACNA1C affects brain circuitries related to mental illness
    • Bigos KL, Mattay VS, Callicott JH, et al. Genetic variation in CACNA1C affects brain circuitries related to mental illness. Arch Gen Psychiatry. 2010;67(9):939-945.
    • (2010) Arch Gen Psychiatry , vol.67 , Issue.9 , pp. 939-945
    • Bigos, K.L.1    Mattay, V.S.2    Callicott, J.H.3
  • 32
    • 81255144051 scopus 로고    scopus 로고
    • The association of genetic variation in CACNA1C with structure and function of a frontotemporal system
    • Wang F, McIntosh AM, He Y, Gelernter J, Blumberg HP. The association of genetic variation in CACNA1C with structure and function of a frontotemporal system. Bipolar Disord. 2011;13(7-8):696-700.
    • (2011) Bipolar Disord , vol.13 , Issue.7-8 , pp. 696-700
    • Wang, F.1    McIntosh, A.M.2    He, Y.3    Gelernter, J.4    Blumberg, H.P.5
  • 33
    • 84865524813 scopus 로고    scopus 로고
    • The impact of the CACNA1C risk allele on limbic structures and facial emotions recognition in bipolar disorder subjects and healthy controls
    • Soeiro-de-Souza MG, Otaduy MC, Dias CZ, Bio DS, Machado-Vieira R, Moreno RA. The impact of the CACNA1C risk allele on limbic structures and facial emotions recognition in bipolar disorder subjects and healthy controls. J Affect Disord. 2012;141(1):94-101.
    • (2012) J Affect Disord , vol.141 , Issue.1 , pp. 94-101
    • Soeiro-de-Souza, M.G.1    Otaduy, M.C.2    Dias, C.Z.3    Bio, D.S.4    Machado-Vieira, R.5    Moreno, R.A.6
  • 35
    • 84855908821 scopus 로고    scopus 로고
    • The effects of CACNA1C gene polymorphism on spatial working memory in both healthy controls and patients with schizophrenia or bipolar disorder
    • Zhang Q, Shen Q, Xu Z, et al. The effects of CACNA1C gene polymorphism on spatial working memory in both healthy controls and patients with schizophrenia or bipolar disorder. Neuropsychopharmacology. 2012;37(3):677-684.
    • (2012) Neuropsychopharmacology , vol.37 , Issue.3 , pp. 677-684
    • Zhang, Q.1    Shen, Q.2    Xu, Z.3
  • 36
    • 84896397953 scopus 로고    scopus 로고
    • Association of rs1006737 in CACNA1C with alterations in prefrontal activation and fronto-hippocampal connectivity
    • Epub February 13
    • Paulus FM, Bedenbender J, Krach S, et al. Association of rs1006737 in CACNA1C with alterations in prefrontal activation and fronto-hippocampal connectivity. Hum Brain Mapp. Epub February 13, 2013.
    • (2013) Hum Brain Mapp
    • Paulus, F.M.1    Bedenbender, J.2    Krach, S.3
  • 37
    • 84876296688 scopus 로고    scopus 로고
    • Identification of risk loci with shared effects on five major psychiatric disorders: A genome-wide analysis
    • Cross-Disorder Group of the Psychiatric Genomics Consortium
    • Cross-Disorder Group of the Psychiatric Genomics Consortium, Smoller JW, Craddock N, et al. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet. 2013;381(9875):1371-1379.
    • (2013) Lancet , vol.381 , Issue.9875 , pp. 1371-1379
    • Smoller, J.W.1    Craddock, N.2
  • 38
    • 84888296163 scopus 로고    scopus 로고
    • Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample
    • Green EK, Hamshere M, Forty L, et al. Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample. Mol Psychiatry. 2013;18(12):1302-1307.
    • (2013) Mol Psychiatry , vol.18 , Issue.12 , pp. 1302-1307
    • Green, E.K.1    Hamshere, M.2    Forty, L.3
  • 39
    • 84878220679 scopus 로고    scopus 로고
    • Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC
    • Hamshere ML, Walters JT, Smith R, et al. Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC. Mol Psychiatry. 2013;18(6):708-712.
    • (2013) Mol Psychiatry , vol.18 , Issue.6 , pp. 708-712
    • Hamshere, M.L.1    Walters, J.T.2    Smith, R.3
  • 40
    • 5344223383 scopus 로고    scopus 로고
    • Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism
    • Splawski I, Timothy KW, Sharpe LM, et al. Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism. Cell. 2004;119(1):19-31.
    • (2004) Cell , vol.119 , Issue.1 , pp. 19-31
    • Splawski, I.1    Timothy, K.W.2    Sharpe, L.M.3
  • 41
    • 84872519179 scopus 로고    scopus 로고
    • Gene mutations in cardiac arrhythmias: A review of recent evidence in ion channelopathies
    • Hsiao PY, Tien HC, Lo CP, Juang JM, Wang YH, Sung RJ. Gene mutations in cardiac arrhythmias: a review of recent evidence in ion channelopathies. Appl Clin Genet. 2013;6:1-13.
    • (2013) Appl Clin Genet , vol.6 , pp. 1-13
    • Hsiao, P.Y.1    Tien, H.C.2    Lo, C.P.3    Juang, J.M.4    Wang, Y.H.5    Sung, R.J.6
  • 42
    • 84884482008 scopus 로고    scopus 로고
    • Exome sequencing and systems biology converge to identify novel mutations in the L-type calcium channel, CACNA1C, linked to autosomal dominant long QT syndrome
    • Boczek NJ, Best JM, Tester DJ, et al. Exome sequencing and systems biology converge to identify novel mutations in the L-type calcium channel, CACNA1C, linked to autosomal dominant long QT syndrome. Circ Cardiovasc Genet. 2013;6(3):279-289.
    • (2013) Circ Cardiovasc Genet , vol.6 , Issue.3 , pp. 279-289
    • Boczek, N.J.1    Best, J.M.2    Tester, D.J.3
  • 43
    • 0030942181 scopus 로고    scopus 로고
    • Further characterization of the syndrome of right bundle branch block, ST segment elevation, and sudden cardiac death
    • Brugada J, Brugada P. Further characterization of the syndrome of right bundle branch block, ST segment elevation, and sudden cardiac death. J Cardiovasc Electrophysiol. 1997;8(3):325-331.
    • (1997) J Cardiovasc Electrophysiol , vol.8 , Issue.3 , pp. 325-331
    • Brugada, J.1    Brugada, P.2
  • 44
    • 77957900975 scopus 로고    scopus 로고
    • Mood disorder susceptibility gene CACNA1C modifies mood-related behaviors in mice and interacts with sex to influence behavior in mice and diagnosis in humans
    • Dao DT, Mahon PB, Cai X, et al. Mood disorder susceptibility gene CACNA1C modifies mood-related behaviors in mice and interacts with sex to influence behavior in mice and diagnosis in humans. Biol Psychiatry. 2010;68(9):801-810.
    • (2010) Biol Psychiatry , vol.68 , Issue.9 , pp. 801-810
    • Dao, D.T.1    Mahon, P.B.2    Cai, X.3
  • 45
    • 84896697649 scopus 로고    scopus 로고
    • PubMed [homepage on the internet]. Available from, Accessed January 10, 2014
    • PubMed [homepage on the internet]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/. Accessed January 10, 2014.
  • 46
    • 80053385384 scopus 로고    scopus 로고
    • Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4
    • Psychiatric GWAS Consortium Bipolar Disorder Working Group
    • Psychiatric GWAS Consortium Bipolar Disorder Working Group. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nat Genet. 2011;43(10): 977-983.
    • (2011) Nat Genet , vol.43 , Issue.10 , pp. 977-983
  • 47
    • 84888637998 scopus 로고    scopus 로고
    • No evidence for association between bipolar disorder risk gene variants and brain structural phenotypes
    • Tesli M, Egeland R, Sønderby IE, et al. No evidence for association between bipolar disorder risk gene variants and brain structural phenotypes. J Affect Disord. 2013;151(1):291-297.
    • (2013) J Affect Disord , vol.151 , Issue.1 , pp. 291-297
    • Tesli, M.1    Egeland, R.2    Sønderby, I.E.3
  • 48
    • 84878898276 scopus 로고    scopus 로고
    • The risk variant in ODZ4 for bipolar disorder impacts on amygdala activation during reward processing
    • Epub April 24
    • Heinrich A, Lourdusamy A, Tzschoppe J, et al. The risk variant in ODZ4 for bipolar disorder impacts on amygdala activation during reward processing. Bipolar Disord. Epub April 24, 2013.
    • (2013) Bipolar Disord
    • Heinrich, A.1    Lourdusamy, A.2    Tzschoppe, J.3
  • 49
    • 84874261811 scopus 로고    scopus 로고
    • CACNA1C risk variant and amygdala activity in bipolar disorder, schizophrenia and healthy controls
    • Tesli M, Skatun KC, Ousdal OT, et al. CACNA1C risk variant and amygdala activity in bipolar disorder, schizophrenia and healthy controls. PLoS One. 2013;8(2):e56970.
    • (2013) PLoS One , vol.8 , Issue.2
    • Tesli, M.1    Skatun, K.C.2    Ousdal, O.T.3
  • 50
    • 84894664747 scopus 로고    scopus 로고
    • A genome-wide supported variant in CACNA1C influences hippocampal activation during episodic memory encoding and retrieval
    • Epub July 17
    • Krug A, Witt SH, Backes H, et al. A genome-wide supported variant in CACNA1C influences hippocampal activation during episodic memory encoding and retrieval. Eur Arch Psychiatry Clin Neurosci. Epub July 17, 2013.
    • (2013) Eur Arch Psychiatry Clin Neurosci
    • Krug, A.1    Witt, S.H.2    Backes, H.3
  • 51
    • 0033980023 scopus 로고    scopus 로고
    • The mammalian Odz gene family: Homologs of a Drosophila pair-rule gene with expression implying distinct yet overlapping developmental roles
    • Ben-Zur T, Feige E, Motro B, Wides R. The mammalian Odz gene family: homologs of a Drosophila pair-rule gene with expression implying distinct yet overlapping developmental roles. Dev Biol. 2000;217(1): 107-120.
    • (2000) Dev Biol , vol.217 , Issue.1 , pp. 107-120
    • Ben-Zur, T.1    Feige, E.2    Motro, B.3    Wides, R.4
  • 52
    • 0043199720 scopus 로고    scopus 로고
    • The murine Ten-m/Odz genes show distinct but overlapping expression patterns during development and in adult brain
    • Zhou XH, Brandau O, Feng K, et al. The murine Ten-m/Odz genes show distinct but overlapping expression patterns during development and in adult brain. Gene Expr Patterns. 2003;3(4):397-405.
    • (2003) Gene Expr Patterns , vol.3 , Issue.4 , pp. 397-405
    • Zhou, X.H.1    Brandau, O.2    Feng, K.3
  • 53
    • 84865251304 scopus 로고    scopus 로고
    • Teneurin-4 is a novel regulator of oligodendrocyte differentiation and myelination of small-diameter axons in the CNS
    • Suzuki N, Fukushi M, Kosaki K, et al. Teneurin-4 is a novel regulator of oligodendrocyte differentiation and myelination of small-diameter axons in the CNS. J Neurosci. 2012;32(34):11586-11599.
    • (2012) J Neurosci , vol.32 , Issue.34 , pp. 11586-11599
    • Suzuki, N.1    Fukushi, M.2    Kosaki, K.3
  • 54
    • 79952485391 scopus 로고    scopus 로고
    • Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder
    • Cichon S, Mühleisen TW, Degenhardt FA, et al. Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder. Am J Hum Genet. 2011;88(3):372-381.
    • (2011) Am J Hum Genet , vol.88 , Issue.3 , pp. 372-381
    • Cichon, S.1    Mühleisen, T.W.2    Degenhardt, F.A.3
  • 55
    • 84871691393 scopus 로고    scopus 로고
    • Assessment of relatedness between neurocan gene as bipolar disorder susceptibility locus and schizophrenia
    • Oruč L, Kapur-Pojskić L, Ramić J, Pojskić N, Bajrović K. Assessment of relatedness between neurocan gene as bipolar disorder susceptibility locus and schizophrenia. Bosn J Basic Med Sci. 2012;12(4):245-248.
    • (2012) Bosn J Basic Med Sci , vol.12 , Issue.4 , pp. 245-248
    • Oruč, L.1    Kapur-Pojskić, L.2    Ramić, J.3    Pojskić, N.4    Bajrović, K.5
  • 56
    • 84861527496 scopus 로고    scopus 로고
    • Association between schizophrenia and common variation in neurocan (NCAN), a genetic risk factor for bipolar disorder
    • Mühleisen TW, Mattheisen M, Strohmaier J, et al. Association between schizophrenia and common variation in neurocan (NCAN), a genetic risk factor for bipolar disorder. Schizophr Res. 2012;138(1):69-73.
    • (2012) Schizophr Res , vol.138 , Issue.1 , pp. 69-73
    • Mühleisen, T.W.1    Mattheisen, M.2    Strohmaier, J.3
  • 57
    • 84896708835 scopus 로고    scopus 로고
    • Common variation in NCAN, a risk factor for bipolar disorder and schizophrenia, influences local cortical folding in schizophrenia
    • Epub June 24
    • Schultz CC, Mühleisen TW, Nenadic I, et al. Common variation in NCAN, a risk factor for bipolar disorder and schizophrenia, influences local cortical folding in schizophrenia. Psychol Med. Epub June 24, 2013.
    • (2013) Psychol Med
    • Schultz, C.C.1    Mühleisen, T.W.2    Nenadic, I.3
  • 58
    • 0034909716 scopus 로고    scopus 로고
    • Neurocan is dispensable for brain development
    • Zhou XH, Brakebusch C, Matthies H, et al. Neurocan is dispensable for brain development. Mol Cell Biol. 2001;21(17):5970-5978.
    • (2001) Mol Cell Biol , vol.21 , Issue.17 , pp. 5970-5978
    • Zhou, X.H.1    Brakebusch, C.2    Matthies, H.3
  • 59
    • 13444301122 scopus 로고    scopus 로고
    • Extracellular matrix alterations in brains lacking four of its components
    • Rauch U, Zhou XH, Roos G. Extracellular matrix alterations in brains lacking four of its components. Biochem Biophys Res Commun. 2005;328(2):608-617.
    • (2005) Biochem Biophys Res Commun , vol.328 , Issue.2 , pp. 608-617
    • Rauch, U.1    Zhou, X.H.2    Roos, G.3
  • 60
    • 77958497833 scopus 로고    scopus 로고
    • Exploring genetic determinants of plasma total cholesterol levels and their predictive value in a longitudinal study
    • Lu Y, Feskens EJ, Boer JM, et al. Exploring genetic determinants of plasma total cholesterol levels and their predictive value in a longitudinal study. Atherosclerosis. 2010;213(1):200-205.
    • (2010) Atherosclerosis , vol.213 , Issue.1 , pp. 200-205
    • Lu, Y.1    Feskens, E.J.2    Boer, J.M.3
  • 61
    • 84855185423 scopus 로고    scopus 로고
    • Sex-specific association of rs16996148 SNP in the NCAN/CILP2/PBX4 and serum lipid levels in the Mulao and Han populations
    • Yan TT, Yin RX, Li Q, et al. Sex-specific association of rs16996148 SNP in the NCAN/CILP2/PBX4 and serum lipid levels in the Mulao and Han populations. Lipids Health Dis. 2011;10:248.
    • (2011) Lipids Health Dis , vol.10 , pp. 248
    • Yan, T.T.1    Yin, R.X.2    Li, Q.3
  • 62
    • 81055145752 scopus 로고    scopus 로고
    • Genetic variants at newly identified lipid loci are associated with coronary heart disease in a Chinese Han population
    • Zhou L, Ding H, Zhang X, et al. Genetic variants at newly identified lipid loci are associated with coronary heart disease in a Chinese Han population. PLoS One. 2011;6(11):e27481.
    • (2011) PLoS One , vol.6 , Issue.11
    • Zhou, L.1    Ding, H.2    Zhang, X.3
  • 63
    • 79953745343 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits
    • Speliotes EK, Yerges-Armstrong LM, Wu J, et al. Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits. PLoS Genet. 2011;7(3):e1001324.
    • (2011) PLoS Genet , vol.7 , Issue.3
    • Speliotes, E.K.1    Yerges-Armstrong, L.M.2    Wu, J.3
  • 64
    • 84876083866 scopus 로고    scopus 로고
    • Genetic variation at NCAN locus is associated with inflammation and fibrosis in non-alcoholic fatty liver disease in morbid obesity
    • Gorden A, Yang R, Yerges-Armstrong LM, et al. Genetic variation at NCAN locus is associated with inflammation and fibrosis in non-alcoholic fatty liver disease in morbid obesity. Hum Hered. 2013;75(1): 34-43.
    • (2013) Hum Hered , vol.75 , Issue.1 , pp. 34-43
    • Gorden, A.1    Yang, R.2    Yerges-Armstrong, L.M.3
  • 65
    • 67449128717 scopus 로고    scopus 로고
    • Large scale replication analysis of loci associated with lipid concentrations in a Japanese population
    • Nakayama K, Bayasgalan T, Yamanaka K, et al. Large scale replication analysis of loci associated with lipid concentrations in a Japanese population. J Med Genet. 2009;46(6):370-374.
    • (2009) J Med Genet , vol.46 , Issue.6 , pp. 370-374
    • Nakayama, K.1    Bayasgalan, T.2    Yamanaka, K.3
  • 66
    • 84896707124 scopus 로고    scopus 로고
    • Online Mendelian Inheritance in Man (OMIM) [homepage on the internet]. Available from, Accessed January 10, 2014
    • Online Mendelian Inheritance in Man (OMIM) [homepage on the internet]. Available from: http://www.ncbi.nlm.nih.gov/omim. Accessed January 10, 2014.
  • 67
    • 0037065539 scopus 로고    scopus 로고
    • Psychotic illness in people with Prader Willi syndrome due to chromosome 15 maternal uniparental disomy
    • Boer H, Holland A, Whittington J, Butler J, Webb T, Clarke D. Psychotic illness in people with Prader Willi syndrome due to chromosome 15 maternal uniparental disomy. Lancet. 2002;359(9301):135-136.
    • (2002) Lancet , vol.359 , Issue.9301 , pp. 135-136
    • Boer, H.1    Holland, A.2    Whittington, J.3    Butler, J.4    Webb, T.5    Clarke, D.6
  • 68
    • 80054848222 scopus 로고    scopus 로고
    • Microdeletion/microduplication of proximal 15q11.2 between BP1 and BP2: A susceptibility region for neurological dysfunction including developmental and language delay
    • Burnside RD, Pasion R, Mikhail FM, et al. Microdeletion/microduplication of proximal 15q11.2 between BP1 and BP2: a susceptibility region for neurological dysfunction including developmental and language delay. Hum Genet. 2011;130(4):517-528.
    • (2011) Hum Genet , vol.130 , Issue.4 , pp. 517-528
    • Burnside, R.D.1    Pasion, R.2    Mikhail, F.M.3
  • 70
    • 67649888504 scopus 로고    scopus 로고
    • Characteristics and frequency of seizure disorder in 56 patients with Prader-Willi syndrome
    • Fan Z, Greenwood R, Fisher A, Pendyal S, Powell CM. Characteristics and frequency of seizure disorder in 56 patients with Prader-Willi syndrome. Am J Med Genet A. 2009;149A(7):1581-1584.
    • (2009) Am J Med Genet A , vol.149 A , Issue.7 , pp. 1581-1584
    • Fan, Z.1    Greenwood, R.2    Fisher, A.3    Pendyal, S.4    Powell, C.M.5
  • 71
    • 0028133293 scopus 로고
    • Deletions of a differentially methylated CpG island at the SNRPN gene define a putative imprinting control region
    • Sutcliffe JS, Nakao M, Christian S, et al. Deletions of a differentially methylated CpG island at the SNRPN gene define a putative imprinting control region. Nat Genet. 1994;8(1):52-58.
    • (1994) Nat Genet , vol.8 , Issue.1 , pp. 52-58
    • Sutcliffe, J.S.1    Nakao, M.2    Christian, S.3
  • 72
    • 0015387610 scopus 로고
    • Prader-Willi syndrome. A resumé of 32 cases including an instance of affected first cousins, one of whom is of normal stature and intelligence
    • Hall BD, Smith DW. Prader-Willi syndrome. A resumé of 32 cases including an instance of affected first cousins, one of whom is of normal stature and intelligence. J Pediatr. 1972;81(2):286-293.
    • (1972) J Pediatr , vol.81 , Issue.2 , pp. 286-293
    • Hall, B.D.1    Smith, D.W.2
  • 73
    • 0023806505 scopus 로고
    • Clinical features in a de novo interstitial deletion 15q13 to q15
    • Autio S, Pihko H, Tengström C. Clinical features in a de novo interstitial deletion 15q13 to q15. Clin Genet. 1988;34(5):293-298.
    • (1988) Clin Genet , vol.34 , Issue.5 , pp. 293-298
    • Autio, S.1    Pihko, H.2    Tengström, C.3
  • 74
    • 29144472344 scopus 로고    scopus 로고
    • Unique maternal deletion of 15q in a patient with some symptoms of Prader-Willi syndrome
    • Ninomiya S, Yokoyama Y, Kawakami M, Une T, Maruyama H, Morishima T. Unique maternal deletion of 15q in a patient with some symptoms of Prader-Willi syndrome. Pediatr Int. 2005;47(5):541-545.
    • (2005) Pediatr Int , vol.47 , Issue.5 , pp. 541-545
    • Ninomiya, S.1    Yokoyama, Y.2    Kawakami, M.3    Une, T.4    Maruyama, H.5    Morishima, T.6
  • 75
    • 39749154724 scopus 로고    scopus 로고
    • A recurrent 15q13.3 microdeletion syndrome associated with mental retardation and seizures
    • Sharp AJ, Mefford HC, Li K, et al. A recurrent 15q13.3 microdeletion syndrome associated with mental retardation and seizures. Nat Genet. 2008;40(3):322-328.
    • (2008) Nat Genet , vol.40 , Issue.3 , pp. 322-328
    • Sharp, A.J.1    Mefford, H.C.2    Li, K.3
  • 76
    • 59149096726 scopus 로고    scopus 로고
    • 15q13.3 microdeletions increase risk of idiopathic generalized epilepsy
    • Helbig I, Mefford HC, Sharp AJ, et al. 15q13.3 microdeletions increase risk of idiopathic generalized epilepsy. Nat Genet. 2009;41(2):160-162.
    • (2009) Nat Genet , vol.41 , Issue.2 , pp. 160-162
    • Helbig, I.1    Mefford, H.C.2    Sharp, A.J.3
  • 77
    • 74249088463 scopus 로고    scopus 로고
    • Recurrent microdeletions at 15q11.2 and 16p13.11 predispose to idiopathic generalized epilepsies
    • de Kovel CG, Trucks H, Helbig I, et al. Recurrent microdeletions at 15q11.2 and 16p13.11 predispose to idiopathic generalized epilepsies. Brain. 2010;133(Pt 1):23-32.
    • (2010) Brain , vol.133 , Issue.PART 1 , pp. 23-32
    • de Kovel, C.G.1    Trucks, H.2    Helbig, I.3
  • 78
    • 68049129849 scopus 로고    scopus 로고
    • Further delineation of the 15q13 microdeletion and duplication syndromes: A clinical spectrum varying from non-pathogenic to a severe outcome
    • van Bon BW, Mefford HC, Menten B, et al. Further delineation of the 15q13 microdeletion and duplication syndromes: a clinical spectrum varying from non-pathogenic to a severe outcome. J Med Genet. 2009;46(8):511-523.
    • (2009) J Med Genet , vol.46 , Issue.8 , pp. 511-523
    • van Bon, B.W.1    Mefford, H.C.2    Menten, B.3
  • 79
    • 65949085347 scopus 로고    scopus 로고
    • Microdeletion/duplication at 15q13.2q13.3 among individuals with features of autism and other neuropsychiatric disorders
    • Miller DT, Shen Y, Weiss LA, et al. Microdeletion/duplication at 15q13.2q13.3 among individuals with features of autism and other neuropsychiatric disorders. J Med Genet. 2009;46(4):242-248.
    • (2009) J Med Genet , vol.46 , Issue.4 , pp. 242-248
    • Miller, D.T.1    Shen, Y.2    Weiss, L.A.3
  • 80
    • 67349176356 scopus 로고    scopus 로고
    • A 15q13.3 microdeletion segregating with autism
    • Pagnamenta AT, Wing K, Sadighi Akha E, et al. A 15q13.3 microdeletion segregating with autism. Eur J Hum Genet. 2009;17(5):687-692.
    • (2009) Eur J Hum Genet , vol.17 , Issue.5 , pp. 687-692
    • Pagnamenta, A.T.1    Wing, K.2    Sadighi, A.E.3
  • 81
    • 67449114040 scopus 로고    scopus 로고
    • Microdeletion 15q13.3: A locus with incomplete penetrance for autism, mental retardation, and psychiatric disorders
    • Ben-Shachar S, Lanpher B, German JR, et al. Microdeletion 15q13.3: a locus with incomplete penetrance for autism, mental retardation, and psychiatric disorders. J Med Genet. 2009;46(6):382-388.
    • (2009) J Med Genet , vol.46 , Issue.6 , pp. 382-388
    • Ben-Shachar, S.1    Lanpher, B.2    German, J.R.3
  • 82
    • 80053903662 scopus 로고    scopus 로고
    • Copy number variants of schizophrenia susceptibility loci are associated with a spectrum of speech and developmental delays and behavior problems
    • Sahoo T, Theisen A, Rosenfeld JA, et al. Copy number variants of schizophrenia susceptibility loci are associated with a spectrum of speech and developmental delays and behavior problems. Genet Med. 2011;13(10):868-880.
    • (2011) Genet Med , vol.13 , Issue.10 , pp. 868-880
    • Sahoo, T.1    Theisen, A.2    Rosenfeld, J.A.3
  • 83
    • 70649089208 scopus 로고    scopus 로고
    • A small recurrent deletion within 15q13.3 is associated with a range of neurodevelopmental phenotypes
    • Shinawi M, Schaaf CP, Bhatt SS, et al. A small recurrent deletion within 15q13.3 is associated with a range of neurodevelopmental phenotypes. Nat Genet. 2009;41(12):1269-1271.
    • (2009) Nat Genet , vol.41 , Issue.12 , pp. 1269-1271
    • Shinawi, M.1    Schaaf, C.P.2    Bhatt, S.S.3
  • 84
    • 84874980921 scopus 로고    scopus 로고
    • Identification of single gene deletions at 15q13.3: Further evidence that CHRNA7 causes the 15q13.3 microdeletion syndrome phenotype
    • Hoppman-Chaney N, Wain K, Seger PR, Superneau DW, Hodge JC. Identification of single gene deletions at 15q13.3: further evidence that CHRNA7 causes the 15q13.3 microdeletion syndrome phenotype. Clin Genet. 2013;83(4):345-351.
    • (2013) Clin Genet , vol.83 , Issue.4 , pp. 345-351
    • Hoppman-Chaney, N.1    Wain, K.2    Seger, P.R.3    Superneau, D.W.4    Hodge, J.C.5
  • 85
    • 78049242136 scopus 로고    scopus 로고
    • Homozygous loss of CHRNA7 on chromosome 15q13.3 causes severe encephalopathy with seizures and hypotonia
    • Endris V, Hackmann K, Neuhann TM, et al. Homozygous loss of CHRNA7 on chromosome 15q13.3 causes severe encephalopathy with seizures and hypotonia. Am J Med Genet A. 2010;152A(11):2908-2911.
    • (2010) Am J Med Genet A , vol.152 A , Issue.11 , pp. 2908-2911
    • Endris, V.1    Hackmann, K.2    Neuhann, T.M.3
  • 86
    • 84896710057 scopus 로고    scopus 로고
    • GeneReviews™ [internet]. Edited by Roberta A Pagon, Editor-in-chief, Margaret P Adam, Thomas D Bird, Cynthia R Dolan, Chin-To Fong, Richard JH Smith, and Karen Stephens. Seattle (WA): University of Washington, Seattle; 1993-2014. Available from, Accessed October 18, 2013
    • GeneReviews™ [internet]. Edited by Roberta A Pagon, Editor-in-chief, Margaret P Adam, Thomas D Bird, Cynthia R Dolan, Chin-To Fong, Richard JH Smith, and Karen Stephens. Seattle (WA): University of Washington, Seattle; 1993-2014. Available from http://www.ncbi.nlm.nih.gov/books/. Accessed October 18, 2013.
  • 87
    • 0023114615 scopus 로고
    • Behaviour disorder in monosomy 10qter
    • Mehta L, Duckett DP, Young ID. Behaviour disorder in monosomy 10qter. J Med Genet. 1987;24(3):185-186.
    • (1987) J Med Genet , vol.24 , Issue.3 , pp. 185-186
    • Mehta, L.1    Duckett, D.P.2    Young, I.D.3
  • 88
    • 32444435911 scopus 로고    scopus 로고
    • A subterminal deletion of the long arm of chromosome 10: A clinical report and review
    • Courtens W, Wuyts W, Rooms L, Pera SB, Wauters J. A subterminal deletion of the long arm of chromosome 10: a clinical report and review. Am J Med Genet A. 2006;140(4):402-409.
    • (2006) Am J Med Genet A , vol.140 , Issue.4 , pp. 402-409
    • Courtens, W.1    Wuyts, W.2    Rooms, L.3    Pera, S.B.4    Wauters, J.5
  • 89
    • 63749090180 scopus 로고    scopus 로고
    • Molecular (SNP) analyses of overlapping hemizygous deletions of 10q25.3 to 10qter in four patients: Evidence for HMX2 and HMX3 as candidate genes in hearing and vestibular function
    • Miller ND, Nance MA, Wohler ES, et al. Molecular (SNP) analyses of overlapping hemizygous deletions of 10q25.3 to 10qter in four patients: evidence for HMX2 and HMX3 as candidate genes in hearing and vestibular function. Am J Med Genet A. 2009;149A(4):669-680.
    • (2009) Am J Med Genet A , vol.149 A , Issue.4 , pp. 669-680
    • Miller, N.D.1    Nance, M.A.2    Wohler, E.S.3
  • 90
    • 67650908148 scopus 로고    scopus 로고
    • Identification of critical regions for clinical features of distal 10q deletion syndrome
    • Yatsenko SA, Kruer MC, Bader PI, et al. Identification of critical regions for clinical features of distal 10q deletion syndrome. Clin Genet. 2009;76(1):54-62.
    • (2009) Clin Genet , vol.76 , Issue.1 , pp. 54-62
    • Yatsenko, S.A.1    Kruer, M.C.2    Bader, P.I.3
  • 91
    • 0242426672 scopus 로고    scopus 로고
    • Deletion of the distal long arm of chromosome 10; is there a characteristic phenotype? A report of 15 de novo and familial cases
    • Irving M, Hanson H, Turnpenny P, et al. Deletion of the distal long arm of chromosome 10; is there a characteristic phenotype? A report of 15 de novo and familial cases. Am J Med Genet A. 2003;123A(2):153-163.
    • (2003) Am J Med Genet A , vol.123 A , Issue.2 , pp. 153-163
    • Irving, M.1    Hanson, H.2    Turnpenny, P.3
  • 92
    • 27444447025 scopus 로고    scopus 로고
    • Clinical features of 78 adults with 22q11 deletion syndrome
    • Bassett AS, Chow EW, Husted J, et al. Clinical features of 78 adults with 22q11 deletion syndrome. Am J Med Genet A. 2005;138(4):307-313.
    • (2005) Am J Med Genet A , vol.138 , Issue.4 , pp. 307-313
    • Bassett, A.S.1    Chow, E.W.2    Husted, J.3
  • 94
    • 84857366623 scopus 로고    scopus 로고
    • Occurrence of affective disorders compared to other psychiatric disorders in children and adolescents with 22q11.2 deletion syndrome
    • Jolin EM, Weller RA, Weller EB. Occurrence of affective disorders compared to other psychiatric disorders in children and adolescents with 22q11.2 deletion syndrome. J Affect Disord. 2012;136(3):222-228.
    • (2012) J Affect Disord , vol.136 , Issue.3 , pp. 222-228
    • Jolin, E.M.1    Weller, R.A.2    Weller, E.B.3
  • 95
    • 33947357128 scopus 로고    scopus 로고
    • Manic symptoms and behavioral dysregulation in youth with velocardiofacial syndrome (22q11.2 deletion syndrome)
    • Aneja A, Fremont WP, Antshel KM, et al. Manic symptoms and behavioral dysregulation in youth with velocardiofacial syndrome (22q11.2 deletion syndrome). J Child Adolesc Psychopharmacol. 2007;17(1):105-114.
    • (2007) J Child Adolesc Psychopharmacol , vol.17 , Issue.1 , pp. 105-114
    • Aneja, A.1    Fremont, W.P.2    Antshel, K.M.3
  • 96
    • 0019352243 scopus 로고
    • The velo-cardio-facial syndrome: A clinical and genetic analysis
    • Shprintzen RJ, Goldberg RB, Young D, Wolford L. The velo-cardio-facial syndrome: a clinical and genetic analysis. Pediatrics. 1981;67(2):167-172.
    • (1981) Pediatrics , vol.67 , Issue.2 , pp. 167-172
    • Shprintzen, R.J.1    Goldberg, R.B.2    Young, D.3    Wolford, L.4
  • 97
    • 44149115417 scopus 로고    scopus 로고
    • Velo-cardio-facial syndrome: 30 Years of study
    • Shprintzen RJ. Velo-cardio-facial syndrome: 30 Years of study. Dev Disabil Res Rev. 2008;14(1):3-10.
    • (2008) Dev Disabil Res Rev , vol.14 , Issue.1 , pp. 3-10
    • Shprintzen, R.J.1
  • 98
    • 33750414349 scopus 로고    scopus 로고
    • The velocardiofacial syndrome in older age: Dementia and autistic features
    • Evers LJ, Vermaak MP, Engelen JJ, Curfs LM. The velocardiofacial syndrome in older age: dementia and autistic features. Genet Couns. 2006;17(3):333-340.
    • (2006) Genet Couns , vol.17 , Issue.3 , pp. 333-340
    • Evers, L.J.1    Vermaak, M.P.2    Engelen, J.J.3    Curfs, L.M.4
  • 100
    • 84876789534 scopus 로고    scopus 로고
    • Smith-Magenis syndrome
    • De Leersnyder H. Smith-Magenis syndrome. Handb Clin Neurol. 2013;111:295-2966.
    • (2013) Handb Clin Neurol , vol.111 , pp. 295-2966
    • de Leersnyder, H.1
  • 101
    • 27744540813 scopus 로고    scopus 로고
    • RAI1 variations in Smith-Magenis syndrome patients without 17p11.2 deletions
    • Girirajan S, Elsas LJ 2nd, Devriendt K, Elsea SH. RAI1 variations in Smith-Magenis syndrome patients without 17p11.2 deletions. J Med Genet. 2005;42(11):820-828.
    • (2005) J Med Genet , vol.42 , Issue.11 , pp. 820-828
    • Girirajan, S.1    Elsas II, L.J.2    Devriendt, K.3    Elsea, S.H.4
  • 102
    • 79956061548 scopus 로고    scopus 로고
    • Smith-Magenis syndrome: Haploinsufficiency of RAI1 results in altered gene regulation in neurological and metabolic pathways
    • Elsea SH, Williams SR. Smith-Magenis syndrome: haploinsufficiency of RAI1 results in altered gene regulation in neurological and metabolic pathways. Expert Rev Mol Med. 2011;13:e14.
    • (2011) Expert Rev Mol Med , vol.13
    • Elsea, S.H.1    Williams, S.R.2
  • 103
    • 0029978246 scopus 로고    scopus 로고
    • Molecular analyses of 17p11.2 deletion in 62 Smith-Magenis syndrome patients
    • Juyal RC, Figuera LE, Hauge X, et al. Molecular analyses of 17p11.2 deletion in 62 Smith-Magenis syndrome patients. Am J Med Genet. 1996;58:998-1007.
    • (1996) Am J Med Genet , vol.58 , pp. 998-1007
    • Juyal, R.C.1    Figuera, L.E.2    Hauge, X.3
  • 104
    • 84883668329 scopus 로고    scopus 로고
    • New ethical issues for genetic counseling in common mental disorders
    • Gershon ES, Alliey-Rodriguez N. New ethical issues for genetic counseling in common mental disorders. Am J Psychiatry. 2013;170(9): 968-976.
    • (2013) Am J Psychiatry , vol.170 , Issue.9 , pp. 968-976
    • Gershon, E.S.1    Alliey-Rodriguez, N.2
  • 105
    • 0002519666 scopus 로고    scopus 로고
    • Models of public health genetic policy development
    • In: Khoury MJ, Burke W, Thomson EJ, editors, Oxford, UK: Oxford University Press
    • Wilfond BS, Thomson EJ. Models of public health genetic policy development. In: Khoury MJ, Burke W, Thomson EJ, editors. Genetics and Public Health in the 21th Century. Oxford, UK: Oxford University Press; 2000:61-81.
    • (2000) Genetics and Public Health In the 21th Century , pp. 61-81
    • Wilfond, B.S.1    Thomson, E.J.2


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