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Volumn 75, Issue 1, 2013, Pages 34-43

Genetic variation at NCAN locus is associated with inflammation and fibrosis in non-alcoholic fatty liver disease in morbid obesity

Author keywords

Cirrhosis; Dyslipidemia; Obesity; Steatohepatitis; Steatosis

Indexed keywords

CHOLESTEROL; LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

EID: 84876083866     PISSN: 00015652     EISSN: 14230062     Source Type: Journal    
DOI: 10.1159/000346195     Document Type: Article
Times cited : (77)

References (43)
  • 2
    • 70349770695 scopus 로고    scopus 로고
    • Epidemiology and natural history of non-alcoholic steatohepatitis
    • Argo CK, Caldwell SH: Epidemiology and natural history of non-alcoholic steatohepatitis. Clin Liver Dis 2009; 13: 511-513.
    • (2009) Clin Liver Dis , vol.13 , pp. 511-513
    • Argo, C.K.1    Caldwell, S.H.2
  • 3
    • 67649306197 scopus 로고    scopus 로고
    • Systematic review of risk factors for fibrosis progression in non-alcoholic steatohepatitis
    • Argo CK, Northup PG, Al-Osaimi AM, Caldwell SH: Systematic review of risk factors for fibrosis progression in non-alcoholic steatohepatitis. J Hepatol 2009; 51: 371-379.
    • (2009) J Hepatol , vol.51 , pp. 371-379
    • Argo, C.K.1    Northup, P.G.2    Al-Osaimi, A.M.3    Caldwell, S.H.4
  • 10
    • 77956630787 scopus 로고    scopus 로고
    • PNPLA3 variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease
    • GIANT Consortium, MIGen Consortium, NASH CRN
    • Speliotes EK, Butler JL, Palmer CD, Voight BF, GIANT Consortium, MIGen Consortium, NASH CRN, Hirschhorn JN: PNPLA3 variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease. Hepatology 2010; 52: 904-912.
    • (2010) Hepatology , vol.52 , pp. 904-912
    • Speliotes, E.K.1    Butler, J.L.2    Palmer, C.D.3    Voight, B.F.4    Hirschhorn, J.N.5
  • 11
    • 79953745343 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits
    • Speliotes EK, Yerges-Armstrong LM, Wu J, Hernaez R, Kim LJ, Palmer CD, et al: Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits. PLoS Genet 2011; 7:e1001324.
    • (2011) PLoS Genet , vol.7
    • Speliotes, E.K.1    Yerges-Armstrong, L.M.2    Wu, J.3    Hernaez, R.4    Kim, L.J.5    Palmer, C.D.6
  • 13
    • 79251608232 scopus 로고    scopus 로고
    • The influence of iron status and genetic polymorphisms in the HFE gene on the risk for postoperative complications after bariatric surgery: A prospective cohort study in 1,064 patients
    • Gerhard GS, Chokshi R, Still CD, Benotti P, Wood GC, Freedman-Weiss M, Rider C, Petrick AT: The influence of iron status and genetic polymorphisms in the HFE gene on the risk for postoperative complications after bariatric surgery: a prospective cohort study in 1,064 patients. Patient Saf Surg 2011; 5: 1.
    • (2011) Patient Saf Surg , vol.5 , pp. 1
    • Gerhard, G.S.1    Chokshi, R.2    Still, C.D.3    Benotti, P.4    Wood, G.C.5    Freedman-Weiss, M.6    Rider, C.7    Petrick, A.T.8
  • 16
    • 73449104310 scopus 로고    scopus 로고
    • Five-year outcomes of laparoscopic adjustable gastric banding and laparoscopic roux-en-Y gastric bypass in a comprehensive bariatric surgery program in Canada
    • Christou N, Efthimiou E: Five-year outcomes of laparoscopic adjustable gastric banding and laparoscopic roux-en-Y gastric bypass in a comprehensive bariatric surgery program in Canada. Can J Surg 2009; 52:E249-E258.
    • (2009) Can J Surg , vol.52
    • Christou, N.1    Efthimiou, E.2
  • 18
    • 47549096019 scopus 로고    scopus 로고
    • Relationship of body mass index with demographic and clinical characteristics in the longitudinal assessment of bariatric surgery (LABS)
    • LABS Writing Group for the LABS Consortium
    • LABS Writing Group for the LABS Consortium; Belle SH, Chapman W, Courcoulas AP, Flum DR, Gagner M, et al: Relationship of body mass index with demographic and clinical characteristics in the longitudinal assessment of bariatric surgery (LABS). Surg Obes Relat Dis 2008; 4: 474-480.
    • (2008) Surg Obes Relat Dis , vol.4 , pp. 474-480
    • Belle, S.H.1    Chapman, W.2    Courcoulas, A.P.3    Flum, D.R.4    Gagner, M.5
  • 19
    • 84857984149 scopus 로고    scopus 로고
    • Dyslipidemia in patients with nonalcoholic fatty liver disease
    • Chatrath H, Vuppalanchi R, Chalasani N: Dyslipidemia in patients with nonalcoholic fatty liver disease. Semin Liver Dis 2012; 32: 22-29.
    • (2012) Semin Liver Dis , vol.32 , pp. 22-29
    • Chatrath, H.1    Vuppalanchi, R.2    Chalasani, N.3
  • 20
    • 69249111667 scopus 로고    scopus 로고
    • A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity
    • Sookoian S, Castano GO, Burgueno AL, Gianotti TF, Rosselli MS, Pirola CJ: A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity. J Lipid Res 2009; 50: 2111-2116.
    • (2009) J Lipid Res , vol.50 , pp. 2111-2116
    • Sookoian, S.1    Castano, G.O.2    Burgueno, A.L.3    Gianotti, T.F.4    Rosselli, M.S.5    Pirola, C.J.6
  • 21
    • 79957462315 scopus 로고    scopus 로고
    • Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease
    • Sookoian S, Pirola CJ: Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease. Hepatology 2011; 53: 1883-1894.
    • (2011) Hepatology , vol.53 , pp. 1883-1894
    • Sookoian, S.1    Pirola, C.J.2
  • 22
    • 77950607738 scopus 로고    scopus 로고
    • Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease
    • Valenti L, Al-Serri A, Daly AK, Galmozzi E, Rametta R, Dongiovanni P, et al: Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease. Hepatology 2010; 51: 1209-1217.
    • (2010) Hepatology , vol.51 , pp. 1209-1217
    • Valenti, L.1    Al-Serri, A.2    Daly, A.K.3    Galmozzi, E.4    Rametta, R.5    Dongiovanni, P.6
  • 24
    • 84862491622 scopus 로고    scopus 로고
    • Paradoxical lower serum triglyceride levels and higher type 2 diabetes mellitus susceptibility in obese individuals with the PNPLA3 148M variant
    • Palmer CN, Maglio C, Pirazzi C, Burza MA, Adiels M, Burch L, et al: Paradoxical lower serum triglyceride levels and higher type 2 diabetes mellitus susceptibility in obese individuals with the PNPLA3 148M variant. PLoS One 2012; 7:e39362.
    • (2012) PLoS One , vol.7
    • Palmer, C.N.1    Maglio, C.2    Pirazzi, C.3    Burza, M.A.4    Adiels, M.5    Burch, L.6
  • 26
    • 77957310400 scopus 로고    scopus 로고
    • The GCKR rs780094 polymorphism is associated with susceptibility of type 2 diabetes, reduced fasting plasma glucose levels, increased triglycerides levels and lower HOMA-IR in Japanese population
    • Onuma H, Tabara Y, Kawamoto R, Shimizu I, Kawamura R, Takata Y, Nishida W, Ohashi J, Miki T, Kohara K, Makino H, Osawa H: The GCKR rs780094 polymorphism is associated with susceptibility of type 2 diabetes, reduced fasting plasma glucose levels, increased triglycerides levels and lower HOMA-IR in Japanese population. J Hum Genet 2010; 55: 600-604.
    • (2010) J Hum Genet , vol.55 , pp. 600-604
    • Onuma, H.1    Tabara, Y.2    Kawamoto, R.3    Shimizu, I.4    Kawamura, R.5    Takata, Y.6    Nishida, W.7    Ohashi, J.8    Miki, T.9    Kohara, K.10    Makino, H.11    Osawa, H.12
  • 32
    • 0029913511 scopus 로고    scopus 로고
    • Analysis of neurocan structures interacting with the neural cell adhesion molecule N-CAM
    • DOI 10.1074/jbc.271.44.27304
    • Retzler C, Gohring W, Rauch U: Analysis of neurocan structures interacting with the neural cell adhesion molecule N-CAM. J Biol Chem 1996; 271: 27304-27310. (Pubitemid 26367284)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.44 , pp. 27304-27310
    • Retzler, C.1    Gohring, W.2    Rauch, U.3
  • 33
    • 0028227022 scopus 로고
    • The neuronal chondroitin sulfate proteoglycan neurocan binds to the neural cell adhesion molecules Ng-CAM/L1/NILE and N-CAM, and inhibits neuronal adhesion and neurite outgrowth
    • Friedlander DR, Milev P, Karthikeyan L, Margolis RK, Margolis RU, Grumet M: The neuronal chondroitin sulfate proteoglycan neurocan binds to the neural cell adhesion molecules ng-CAM/L1/NILE and N-CAM, and inhibits neuronal adhesion and neurite outgrowth. J Cell Biol 1994; 125: 669-680. (Pubitemid 24149848)
    • (1994) Journal of Cell Biology , vol.125 , Issue.3 , pp. 669-680
    • Friedlander, D.R.1    Milev, P.2    Karthikeyan, L.3    Margolis, R.K.4    Margolis, R.U.5    Grumet, M.6
  • 34
    • 0028360757 scopus 로고
    • Interactions with tenascin and differential effects on cell adhesion of neurocan and phosphacan, two major chondroitin sulfate proteoglycans of nervous tissue
    • Grumet M, Milev P, Sakurai T, Karthikeyan L, Bourdon M, Margolis RK, Margolis RU: Interactions with tenascin and differential effects on cell adhesion of neurocan and phosphacan, two major chondroitin sulfate proteoglycans of nervous tissue. J Biol Chem 1994; 269: 12142-12146. (Pubitemid 24196713)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.16 , pp. 12142-12146
    • Grumet, M.1    Milev, P.2    Sakurai, T.3    Karthikeyan, L.4    Bourdon, M.5    Margolis, R.K.6    Margolis, R.U.7
  • 38
    • 4644227229 scopus 로고    scopus 로고
    • Intracerebroventricular neuropeptide Y infusion precludes inhibition of glucose and VLDL production by insulin
    • DOI 10.2337/diabetes.53.10.2529
    • van den Hoek AM, Voshol PJ, Karnekamp BN, Buijs RM, Romijn JA, Havekes LM, Pijl H: Intracerebroventricular neuropeptide Y infusion precludes inhibition of glucose and VLDL production by insulin. Diabetes 2004; 53: 2529-2534. (Pubitemid 39299258)
    • (2004) Diabetes , vol.53 , Issue.10 , pp. 2529-2534
    • Van Den Hoek, A.M.1    Voshol, P.J.2    Karnekamp, B.N.3    Buijs, R.M.4    Romijn, J.A.5    Havekes, L.M.6    Pijl, H.7
  • 39
    • 0033848968 scopus 로고    scopus 로고
    • Vagal circuitry mediating cephalic-phase responses to food
    • Powley TL: Vagal circuitry mediating cephalic-phase responses to food. Appetite 2000; 34: 184-188.
    • (2000) Appetite , vol.34 , pp. 184-188
    • Powley, T.L.1
  • 42
    • 0025264443 scopus 로고
    • Measurement of very low density and low density lipoprotein apolipoprotein (apo) B-100 and high density lipoprotein apo A-I production in human subjects using deuterated leucine. Effect of fasting and feeding
    • Cohn JS, Wagner DA, Cohn SD, Millar JS, Schaefer EJ: Measurement of very low density and low density lipoprotein apolipoprotein (apo) B-100 and high density lipoprotein apo A-I production in human subjects using deuterated leucine. Effect of fasting and feeding. J Clin Invest 1990; 85: 804-811. (Pubitemid 20087484)
    • (1990) Journal of Clinical Investigation , vol.85 , Issue.3 , pp. 804-811
    • Cohn, J.S.1    Wagner, D.A.2    Cohn, S.D.3    Millar, J.S.4    Schaefer, E.J.5
  • 43
    • 48249100537 scopus 로고    scopus 로고
    • Central nervous system neuropeptide y signaling modulates VLDL triglyceride secretion
    • Stafford JM, Yu F, Printz R, Hasty AH, Swift LL, Niswender KD: Central nervous system neuropeptide Y signaling modulates VLDL triglyceride secretion. Diabetes 2008; 57: 1482-1490.
    • (2008) Diabetes , vol.57 , pp. 1482-1490
    • Stafford, J.M.1    Yu, F.2    Printz, R.3    Hasty, A.H.4    Swift, L.L.5    Niswender, K.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.