Study of anti-fibrillogenic activity of iron(II) clathrochelates

Bioorganic and Medicinal Chemistry

Volumn 22, Issue 6, 2014, Pages 1883-1888

  Kovalska, Vladyslava B ^a   Losytskyy, Mykhaylo Yu ^a   Varzatskii, Oleg A ^b   Cherepanov, Vsevolod V ^c   Voloshin, Yan Z ^d   Mokhir, Andriy A ^e   Yarmoluk, Sergiy M ^a   Volkov, Sergiy V ^b  

^a INSTITUTE OF MOLECULAR BIOLOGY AND GENETICS   (Ukraine)

^b INSTITUTE OF GENERAL AND INORGANIC CHEMISTRY   (Ukraine)

^c INSTITUTE OF HYDROBIOLOGY   (Ukraine)

^d A N NESMEYANOV INSTITUTE OF ORGANOELEMENT COMPOUNDS   (Russian Federation)

^e UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

AFM; Amyloid fibrils; Fibrillization inhibition; Flow cytometry; Fluorescent detection; Iron(II) clathrochelates

Indexed keywords

BENZOIC ACID DERIVATIVE; INSULIN; IRON CHELATE; IRON CLATHROCHELATE; UNCLASSIFIED DRUG; AMYLOID; FERROUS ION; MACROCYCLIC COMPOUND;

ANTIFIBRILLOGENIC ACTIVITY; ARTICLE; ATOMIC FORCE MICROSCOPY; CHEMICAL REACTION KINETICS; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG ACTIVITY; FLOW CYTOMETRY; FLUORESCENCE ANALYSIS; IC 50; MOLECULAR SIZE; PROTEIN AGGREGATION; ANTAGONISTS AND INHIBITORS; CHEMISTRY; CONFORMATION; DOSE RESPONSE; HUMAN; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

AMYLOID; DOSE-RESPONSE RELATIONSHIP, DRUG; FERROUS COMPOUNDS; HUMANS; INSULIN; MACROCYCLIC COMPOUNDS; MOLECULAR CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84896709878     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2014.01.048     Document Type: Article

References (19)

1. A. Aguzzi, and T. O'Connor Nat. Rev. Drug Disc. 9 2010 237
2. V.N. Uversky, and A.L. Fink Biochim. Biophys. Acta 1698 2004 131
3. D.A. Kocisko, W.S. Caughey, R.E. Race, G. Roper, B. Caughey, and J.D. Morrey Antimicrob. Agents Chemother. 50 2006 759
4. S. Taniguchi, N. Suzuki, M. Masuda, S. Hisanaga, T. Iwatsubo, M. Goedert, and M. Hasegawa J. Biol. Chem. 280 2005 7614
5. G.R. Lamberto, A. Binolfi, and M.L. Orcellet et al. Proc. Natl. Acad. Sci. U.S.A. 106 2009 21057
6. V. Kovalska, M. Losytskyy, V. Chernii, K. Volkova, I. Tretyakova, V. Cherepanov, S. Yarmoluk, and S. Volkov Bioorg. Med. Chem. 20 2012 330
7. Voloshin, Y.; Varzatskii, O.; Shul'ga, S.; Novikov, V.; Belov, A.; Makarenko, I.; Dubey, I.; Krivorotenko, D.; Negrutska, V.; Zhizhin, K.; Kuznetsov, N.; Bubnov, Y. Thesis, 10th EUROBIC Conference, Aristotle University of Thessaloniki, Greece, 2010.
8. V. Novikov, O. Varzatskii, V. Negrutska, Y. Bubnov, L. Palchykovska, I. Dubey, and Y. Voloshin J. Inorg. Biochem. 124 2013 42
9. Mykhaylo Y. Losytskyy, Vladyslava B. Kovalska, Oleg A. Varzatskii, Alexander M. Sergeev, Sergiy M. Yarmoluk, and Yan Z. Voloshin J. Fluoresc. 23 2013 889
10. Y.Z. Voloshin, O.A. Varzatskii, A.V. Palchik, Z.A. Starikova, M.Y. Antipin, E.G. Lebed, and Y.N. Bubnov Inorg. Chim. Acta 359 2006 553
11. I.G. Belaya, G.E. Zelinskii, A.S. Belov, O.A. Varzatskii, V.V. Novikov, A.V. Dolganov, H. Kozlowski, Ł. Szyrwiel, Y.N. Bubnov, and Y.Z. Voloshin Polyhedron 40 2012 32
12. Voloshin, Y.Z.; Varzatskii, O.A.; Dubey, I.Y.; Bubnov, Y.N. Thesis, IMEBoron-XIV Conference, Niagara Falls, Canada, 2011.
13. K.D. Volkova, V.B. Kovalska, D. Inshin, Y.L. Slominskii, O.I. Tolmachev, and S.M. Yarmoluk Biotech. Histochem. 86 2011 188
14. K. Volkova, V. Kovalska, M. Losytskyy, K. Fal, N. Derevyanko, Yu. Slominskii, O. Tolmachov, and S. Yarmoluk J. Fluoresc. 21 2011 775
15. V.B. Kovalska, M.Y. Losytskyy, O.I. Tolmachev, Y.L. Slominskii, G.M. Segers-Nolten, V. Subramaniam, and S.M. Yarmoluk J. Fluoresc. 22 2012 1441
16. J. Wall, and A. Solomon Methods Enzymol. 309 1999 460
17. Jonathan Stuart Wall, U.S. Patent 6,423,270 B1, 2002.
18. R. Jansen, W. Dzwolak, and R. Winter Biophys. J. 88 2005 1344
19. Y.S. Choi, J. Kim, G. Bhak, D. Lee, and S.R. Paik Angew. Chem., Int. Ed. 50 2011 6070