-
1
-
-
0030882856
-
Alpha-synuclein in Lewy bodies
-
Spillantini MG, Schmidt ML, Lee VM, Trojanowski JQ, Jakes R, Goedert M (1997) Alpha-synuclein in Lewy bodies. Nature 388:839-840
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
2
-
-
0032568534
-
Alpha-synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies
-
Spillantini MG, Crowther RA, Jakes R, Hasegawa M, Goedert M (1998) Alpha-synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies. Proc Natl Acad Sci India USA 95:6469-6473
-
(1998)
Proc Natl Acad Sci India USA
, vol.95
, pp. 6469-6473
-
-
Spillantini, M.G.1
Crowther, R.A.2
Jakes, R.3
Hasegawa, M.4
Goedert, M.5
-
3
-
-
0037025817
-
Structural transformation and aggregation of human alpha-synuclein in trifluoroethanol: Non-amyloid component sequence is essential and beta-sheet forma tion is prerequisite to aggregation
-
Li HT, Du HN, Tang L, Hu J, Hu HY (2002) Structural transformation and aggregation of human alpha-synuclein in trifluoroethanol: non-amyloid component sequence is essential and beta-sheet forma tion is prerequisite to aggregation. Biopolymers 64:221-226
-
(2002)
Biopolymers
, vol.64
, pp. 221-226
-
-
Li, H.T.1
Du, H.N.2
Tang, L.3
Hu, J.4
Hu, H.Y.5
-
4
-
-
8544264002
-
Impact of the acidic C-terminal region comprising amino acids 109-140 on α-synuclein aggregation in vitro
-
Hoyer W, Cherny D, Subramaniam V, Jovin TM (2004) Impact of the acidic C-terminal region comprising amino acids 109-140 on α-synuclein aggregation in vitro. Biochemistry 43:16233-16242
-
(2004)
Biochemistry
, vol.43
, pp. 16233-16242
-
-
Hoyer, W.1
Cherny, D.2
Subramaniam, V.3
Jovin, T.M.4
-
5
-
-
0036415838
-
Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils
-
Lashuel HA, Petre BM, Wall J, Simon M, Nowak RJ, Walz T, Lansbury PT Jr (2002) Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils. J Mol Biol 322:1089-1102
-
(2002)
J Mol Biol
, vol.322
, pp. 1089-1102
-
-
Lashuel, H.A.1
Petre, B.M.2
Wall, J.3
Simon, M.4
Nowak, R.J.5
Walz, T.6
Lansbury Jr., P.T.7
-
6
-
-
0038386274
-
Zeroing in on the pathogenic form of alpha-synuclein and its mechanism of neurotoxicity in Parkinson's disease
-
Volles MJ, Lansbury PT Jr (2003) Zeroing in on the pathogenic form of alpha-synuclein and its mechanism of neurotoxicity in Parkinson's disease. Biochemistry 42:7871-7878
-
(2003)
Biochemistry
, vol.42
, pp. 7871-7878
-
-
Volles, M.J.1
Lansbury Jr., P.T.2
-
7
-
-
0041845349
-
Certain metals trigger fibrillation of methionine-oxidized α-synuclein
-
Yamin G, Glaser CB, Uversky VN, Fink AL (2003) Certain metals trigger fibrillation of methionine-oxidized α-synuclein. J Biol Chem 278:27630-27635
-
(2003)
J Biol Chem
, vol.278
, pp. 27630-27635
-
-
Yamin, G.1
Glaser, C.B.2
Uversky, V.N.3
Fink, A.L.4
-
8
-
-
0033538541
-
Alpha-synuclein fibrillogenesis is nucleation-dependent. Implications for the pathogenesis of Parkinson's disease
-
Wood SJ, Wypych J, Steavenson S, Louis JC, Citron M, Biere AL (1999) Alpha-synuclein fibrillogenesis is nucleation-dependent. Implications for the pathogenesis of Parkinson's disease. J Biol Chem 274:19509-19512
-
(1999)
J Biol Chem
, vol.274
, pp. 19509-19512
-
-
Wood, S.J.1
Wypych, J.2
Steavenson, S.3
Louis, J.C.4
Citron, M.5
Biere, A.L.6
-
9
-
-
0035800097
-
Vesicle permeabilization by protofibrillar alpha-synuclein: Implications for the pathogenesis and treatment of Parkinson's disease
-
Volles MJ, Lee SJ, Rochet JC, Shtilerman MD, Ding TT, Kessler JC, Lansbury PT Jr (2001) Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease. Biochemistry 40:7812-7819
-
(2001)
Biochemistry
, vol.40
, pp. 7812-7819
-
-
Volles, M.J.1
Lee, S.J.2
Rochet, J.C.3
Shtilerman, M.D.4
Ding, T.T.5
Kessler, J.C.6
Lansbury, P.T.7
-
10
-
-
61549111872
-
α-Synuclein and neuronal cell death
-
Cookson MR (2009) α-Synuclein and neuronal cell death. Mol Neurodegener 4:9-14
-
(2009)
Mol Neurodegener
, vol.4
, pp. 9-14
-
-
Cookson, M.R.1
-
11
-
-
28844441969
-
Secondary structure of alpha-synuclein oligomers:Characterization by Raman and atomic force microscopy
-
Apetri MM,Maiti NC, Zagorski MG, Carey PR, Anderson VE (2006) Secondary structure of alpha-synuclein oligomers:Characterization by Raman and atomic force microscopy. J Mol Biol 355:63-71
-
(2006)
J Mol Biol
, vol.355
, pp. 63-71
-
-
Apetri Mmmaiti, N.C.1
Zagorski, M.G.2
Carey, P.R.3
Anderson, V.E.4
-
12
-
-
0034681163
-
Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to earlyonset Parkinson's disease: Implications for pathogenesis and therapy
-
Conway KA, Lee SJ, Rochet JC, Ding TT, Williamson RE, Lansbury PT Jr (2000) Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to earlyonset Parkinson's disease: implications for pathogenesis and therapy. Proc Natl Acad Sci U S A 97:571-576
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 571-576
-
-
Conway, K.A.1
Lee, S.J.2
Rochet, J.C.3
Ding, T.T.4
Williamson, R.E.5
Lansbury Jr., P.T.6
-
13
-
-
0036415838
-
Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms porelike annular and tubular protofibrils
-
Lashuel HA, Petre BM, Wall J, Simon M, Nowak RJ, Walz T, Lansbury PT Jr (2002) Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms porelike annular and tubular protofibrils. J Mol Biol 322:1089-1102
-
(2002)
J Mol Biol
, vol.322
, pp. 1089-1102
-
-
Lashuel, H.A.1
Petre, B.M.2
Wall, J.3
Simon, M.4
Nowak, R.J.5
Walz, T.6
Lansbury Jr., P.T.7
-
14
-
-
0037072284
-
Annular alphasynuclein proto-brils are produced when spherical protofibrils are incubated in solution or bound to brain-derived membranes
-
Ding TT, Lee SJ, Rochet JC, Lansbury PT (2002) Annular alphasynuclein proto-brils are produced when spherical protofibrils are incubated in solution or bound to brain-derived membranes. Biochemistry 41:10209-10217
-
(2002)
Biochemistry
, vol.41
, pp. 10209-10217
-
-
Ding, T.T.1
Lee, S.J.2
Rochet, J.C.3
Lansbury, P.T.4
-
15
-
-
23044449398
-
Amyloid ion channels:A common structural link for protein-misfolding disease
-
Quist A, Doudevski I, Lin H, Azimova R, Ng D, Frangione B, Kagan B, Ghiso J, Lal R (2005) Amyloid ion channels:a common structural link for protein-misfolding disease. Proc Natl Acad Sci U S A 102:10427-10432
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 10427-10432
-
-
Quist, A.1
Doudevski, I.2
Lin, H.3
Azimova, R.4
Ng, D.5
Frangione, B.6
Kagan, B.7
Ghiso, J.8
Lal, R.9
-
16
-
-
25444433798
-
Characterization of oligomeric intermediates in alphasynuclein fibrillation: FRET studies of Y125W/Y133F/Y136F alpha-synuclein
-
Kaylor J, Bodner N, Edridge S, Yamin G, Hong DP, Fink AL (2005) Characterization of oligomeric intermediates in alphasynuclein fibrillation: FRET studies of Y125W/Y133F/Y136F alpha-synuclein. J Mol Biol 353:357-372
-
(2005)
J Mol Biol
, vol.353
, pp. 357-372
-
-
Kaylor, J.1
Bodner, N.2
Edridge, S.3
Yamin, G.4
Hong, D.P.5
Fink, A.L.6
-
18
-
-
22244456042
-
Detection and characterization of aggregates, prefibrillar amyloidogenic oligomers, and protofibrils using fluorescence spectroscopy
-
Lindgren M, Sörgjerd K, Hammarström P (2005) Detection and characterization of aggregates, prefibrillar amyloidogenic oligomers, and protofibrils using fluorescence spectroscopy. Biophys J 88:4200-4212
-
(2005)
Biophys J
, vol.88
, pp. 4200-4212
-
-
Lindgren, M.1
Sörgjerd, K.2
Hammarström, P.3
-
19
-
-
44649133131
-
Extrinsic fluorescent dyes as tools for protein characterization
-
Hawe A, Sutter M, Jiskoot W (2008) Extrinsic fluorescent dyes as tools for protein characterization. Pharm Res 25(7):1487-1499
-
(2008)
Pharm Res
, vol.25
, Issue.7
, pp. 1487-1499
-
-
Hawe, A.1
Sutter, M.2
Jiskoot, W.3
-
20
-
-
33646349196
-
Methods for enhancing the accuracy and reproducibility of Congo red and Thioflavin T assays
-
Eisert R, Felau L, Brown LR (2006) Methods for enhancing the accuracy and reproducibility of Congo red and Thioflavin T assays. Anal Biochem 353:144-146
-
(2006)
Anal Biochem
, vol.353
, pp. 144-146
-
-
Eisert, R.1
Felau, L.2
Brown, L.R.3
-
21
-
-
38849135987
-
Specific fluorescent detection of fibrillar alpha-synuclein using mono- and trimethine cyanine dyes
-
Volkova KD, Kovalska VB, Balanda AO, Losytskyy MYu, Golub AG, Vermeij RJ, Subramaniam V, Tolmachev OI, Yarmoluk SM (2008) Specific fluorescent detection of fibrillar alpha-synuclein using mono- and trimethine cyanine dyes. Bioorg Med Chem 16:1452-1459
-
(2008)
Bioorg Med Chem
, vol.16
, pp. 1452-1459
-
-
Volkova, K.D.1
Kovalska, V.B.2
Balanda, A.O.3
Losytskyy, M.Yu.4
Golub, A.G.5
Vermeij, R.J.6
Subramaniam, V.7
Tolmachev, O.I.8
Yarmoluk, S.M.9
-
22
-
-
62549166732
-
Explorations of the application of cyanine dyes for quantitative α-synuclein detection
-
Volkova KD, Kovalska VB, Segers-Nolten GM, Veldhuis G, Subramaniam V, Yarmoluk SM (2009) Explorations of the application of cyanine dyes for quantitative α-synuclein detection. Biotech Histochem 84:55-61
-
(2009)
Biotech Histochem
, vol.84
, pp. 55-61
-
-
Volkova, K.D.1
Kovalska, V.B.2
Segers-Nolten, G.M.3
Veldhuis, G.4
Subramaniam, V.5
Yarmoluk, S.M.6
-
23
-
-
80053098661
-
Hydroxy and methoxy substituted thiacarbocyanines for fluorescent detection of amyloid formations
-
Volkova KD, Kovalska VB, Losytskyy MY, Fal KO, Derevyanko NO, Slominskii YL, Tolmachev OI, Yarmoluk SM (2011) Hydroxy and methoxy substituted thiacarbocyanines for fluorescent detection of amyloid formations. J Fluor 21:775-784
-
(2011)
J Fluor
, vol.21
, pp. 775-784
-
-
Volkova, K.D.1
Kovalska, V.B.2
Losytskyy, M.Y.3
Fal, K.O.4
Derevyanko, N.O.5
Slominskii, Y.L.6
Tolmachev, O.I.7
Yarmoluk, S.M.8
-
25
-
-
84869499949
-
Imidadicarbocyanines with substituents in polymethine chain
-
in Russian
-
Zubarovskii VM, Briks YL, Khodot GP (1981) Imidadicarbocyanines with substituents in polymethine chain. Ukr Khim Zh 47 (5):525-528, in Russian
-
(1981)
Ukr Khim Zh
, vol.47
, Issue.5
, pp. 525-528
-
-
Zubarovskii, V.M.1
Briks, Y.L.2
Khodot, G.P.3
-
26
-
-
0000429565
-
Dicarbocyanine dyes from formyldioxene and 3-formyl-5,6-dihydro- 4H-pyran
-
in Russian
-
Slominskii YL, Efimenko NI, Kuznetsov NV, Krasavtsev II (1977) Dicarbocyanine dyes from formyldioxene and 3-formyl-5,6-dihydro- 4H-pyran. Ukr Khim Zh 43(7):711-714, in Russian
-
(1977)
Ukr Khim Zh
, vol.43
, Issue.7
, pp. 711-714
-
-
Slominskii, Y.L.1
Efimenko, N.I.2
Kuznetsov, N.V.3
Krasavtsev, I.I.4
-
27
-
-
26844484301
-
Thiadicarbocyanines with five-membered cycles in chromophore
-
in Russian
-
Slominskii YL, Efimenko NI, Kachkovskii AD, Kurkina LG, Tolmachev AI (1986) Thiadicarbocyanines with five-membered cycles in chromophore. Ukr Khim Zh 52(3):301-307, in Russian
-
(1986)
Ukr Khim Zh
, vol.52
, Issue.3
, pp. 301-307
-
-
Slominskii, Y.L.1
Efimenko, N.I.2
Kachkovskii, A.D.3
Kurkina, L.G.4
Tolmachev, A.I.5
-
28
-
-
33845358566
-
Quantitative morphological analysis reveals ultrastructural diversity of amyloid fibrils from α-synuclein mutants
-
van Raaij ME, Segers-Nolten IM, Subramaniam V (2006) Quantitative morphological analysis reveals ultrastructural diversity of amyloid fibrils from α-synuclein mutants. Biophys J 91:L96-L98
-
(2006)
Biophys J
, vol.91
-
-
Van Raaij, M.E.1
Segers-Nolten, I.M.2
Subramaniam, V.3
-
29
-
-
65549114936
-
Lipid bilayer disruption by oligomeric α-synuclein depends on bilayer charge and accessibility of the hydrophobic core Biochimica et Biophysica Acta (BBA
-
van Rooijen B, Claessens M, Subramaniam V Lipid bilayer disruption by oligomeric α-synuclein depends on bilayer charge and accessibility of the hydrophobic core Biochimica et Biophysica Acta (BBA) -Biomembranes V, 1788, Issue 6, P. 1271-1278
-
Biomembranes
, vol.1788
, Issue.6
, pp. 1271-1278
-
-
Van Rooijen, B.1
Claessens, M.2
Subramaniam, V.3
-
30
-
-
0011701736
-
Photochemical characteristics of cyanine dyes. Part 1. 3,3′-Diethyloxadicarbocyanine iodide and 3,3′- diethylthiadicarbocyanine iodide
-
Dempster DN, Morrow T, Rankin R, Thompson GF (1972) Photochemical characteristics of cyanine dyes. Part 1. 3,3′-Diethyloxadicarbocyanine iodide and 3,3′-diethylthiadicarbocyanine iodide. J Chem Soc Faraday Trans II 68:1479-1496
-
(1972)
J Chem Soc Faraday Trans II
, vol.68
, pp. 1479-1496
-
-
Dempster, D.N.1
Morrow, T.2
Rankin, R.3
Thompson, G.F.4
-
31
-
-
0024733168
-
Fluorescence self-quenching of the molecular forms of rhodamine B in aqueous and ethanolic solutions
-
Lopez Arbeloa F, Ruiz Ojeda P, Lopez Arbeloa I (1989) Fluorescence self-quenching of the molecular forms of rhodamine B in aqueous and ethanolic solutions. J Luminesc 44:105-112
-
(1989)
J Luminesc
, vol.44
, pp. 105-112
-
-
Lopez Arbeloa, F.1
Ruiz Ojeda, P.2
Lopez Arbeloa, I.3
-
32
-
-
0034743730
-
Interactions of cyanine dyes with nucleic acids. XXIV. Aggregation of monomethine cyanine dyes in presence of DNA and its manifestation in absorption and fluorescence spectra
-
Ogul'chansky TY, Losytskyy MYu, Kovalska VB, Yashchuk VM, Yarmoluk SM (2001) Interactions of cyanine dyes with nucleic acids. XXIV. Aggregation of monomethine cyanine dyes in presence of DNA and its manifestation in absorption and fluorescence spectra. Spectrochim Acta A Mol Biomol Spectrosc 57(7):1525-1532
-
(2001)
Spectrochim Acta A Mol Biomol Spectrosc
, vol.57
, Issue.7
, pp. 1525-1532
-
-
Ogul'Chansky, T.Y.1
Losytskyy, M.Yu.2
Kovalska, V.B.3
Yashchuk, V.M.4
Yarmoluk, S.M.5
|