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Volumn 8, Issue 11, 2013, Pages

Meleagrin, a new fabi inhibitor from Penicillium chryosogenum with at least one additional mode of action

Author keywords

[No Author keywords available]

Indexed keywords

ACTINONIN; AMPICILLIN; ANTIINFECTIVE AGENT; BACTERIAL ENZYME; ERYTHROMYCIN; FATTY ACID; MELEAGRIN; NORFLOXACIN; OXACILLIN; PROTEIN FABI; PROTEIN FABI INHIBITOR; PROTEIN FABK; TRICLOSAN; UNCLASSIFIED DRUG;

EID: 84896703765     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0078922     Document Type: Article
Times cited : (48)

References (32)
  • 1
    • 37049001066 scopus 로고    scopus 로고
    • Hospitalizations and deaths caused by methicillin-resistant Staphylococcus aureus, United States, 1999-2005
    • Klein E, Smith DL, Laxminarayan R (2007) Hospitalizations and deaths caused by methicillin-resistant Staphylococcus aureus, United States, 1999-2005. Emerg Infect Dis 13: 1840-1846. (Pubitemid 350248484)
    • (2007) Emerging Infectious Diseases , vol.13 , Issue.12 , pp. 1840-1846
    • Klein, E.1    Smith, D.L.2    Laxminarayan, R.3
  • 2
    • 10944272743 scopus 로고    scopus 로고
    • Antibacterial resistance worldwide: Causes, challenges and responses
    • DOI 10.1038/nm1145
    • Levy SB, Marshall B (2004) Antibacterial resistance worldwide: causes, challenges and responses. Nat Med 10: S122-129. (Pubitemid 40018235)
    • (2004) Nature Medicine , vol.10 , Issue.12 SUPPL.
    • Levy, S.B.1    Marshall, B.2
  • 3
    • 0038779197 scopus 로고    scopus 로고
    • Genetic strategies for antibacterial drug discovery
    • DOI 10.1038/nrg1086
    • Miesel L, Greene J, Black TA (2003) Genetic strategies for antibacterial drug discovery. Nat Rev Genet 4: 442-456. (Pubitemid 36648144)
    • (2003) Nature Reviews Genetics , vol.4 , Issue.6 , pp. 442-456
    • Miesel, L.1    Greene, J.2    Black, T.A.3
  • 4
    • 3042764816 scopus 로고    scopus 로고
    • Fatty acid biosynthesis as a target for novel antibacterials
    • Heath RJ, Rock CO (2004) Fatty acid biosynthesis as a target for novel antibacterials. Curr Opin Investig Drugs 5: 146-153.
    • (2004) Curr Opin Investig Drugs , vol.5 , pp. 146-153
    • Heath, R.J.1    Rock, C.O.2
  • 6
    • 38349161956 scopus 로고    scopus 로고
    • Vibrio cholerae FabV defines a new class of enoyl-acyl carrier protein reductase
    • Massengo-Tiasse RP, Cronan JE (2008) Vibrio cholerae FabV defines a new class of enoyl-acyl carrier protein reductase. Journal of Biological Chemistry 283: 1308-1316.
    • (2008) Journal of Biological Chemistry , vol.283 , pp. 1308-1316
    • Massengo-Tiasse, R.P.1    Cronan, J.E.2
  • 7
    • 75749138079 scopus 로고    scopus 로고
    • Triclosan resistance of Pseudomonas aeruginosa PAO1 is due to FabV, a triclosan-resistant enoyl-acyl carrier protein reductase
    • Zhu L, Lin J, Ma J, Cronan JE, Wang H (2010) Triclosan resistance of Pseudomonas aeruginosa PAO1 is due to FabV, a triclosan-resistant enoyl-acyl carrier protein reductase. Antimicrobial Agents and Chemotherapy 54: 689-698.
    • (2010) Antimicrobial Agents and Chemotherapy , vol.54 , pp. 689-698
    • Zhu, L.1    Lin, J.2    Ma, J.3    Cronan, J.E.4    Wang, H.5
  • 8
  • 9
    • 38949097460 scopus 로고    scopus 로고
    • Inhibitors of FabI, an enzyme drug target in the bacterial fatty acid biosynthesis pathway
    • Lu H, Tonge PJ (2008) Inhibitors of FabI, an enzyme drug target in the bacterial fatty acid biosynthesis pathway. Acc Chem Res 41: 11-20.
    • (2008) Acc Chem Res , vol.41 , pp. 11-20
    • Lu, H.1    Tonge, P.J.2
  • 10
    • 33845894155 scopus 로고    scopus 로고
    • Multi-targeting by monotherapeutic antibacterials
    • Silver LL (2007) Multi-targeting by monotherapeutic antibacterials. Nat Rev Drug Discov 6: 41-55.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 41-55
    • Silver, L.L.1
  • 11
    • 0032490937 scopus 로고    scopus 로고
    • Triclosan targets lipid synthesis
    • McMurry LM, Oethinger M, Levy SB (1998) Triclosan targets lipid synthesis. Nature 394: 531-532.
    • (1998) Nature , vol.394 , pp. 531-532
    • McMurry, L.M.1    Oethinger, M.2    Levy, S.B.3
  • 12
    • 0032472224 scopus 로고    scopus 로고
    • Modification of the NADH of the isoniazid target (InhA) from Mycobacterium tuberculosis
    • DOI 10.1126/science.279.5347.98
    • Rozwarski DA, Grant GA, Barton DH, Jacobs WR Jr, Sacchettini JC (1998) Modification of the NADH of the isoniazid target (InhA) from Mycobacterium tuberculosis. Science 279: 98-102. (Pubitemid 28079164)
    • (1998) Science , vol.279 , Issue.5347 , pp. 98-102
    • Rozwarski, D.A.1    Grant, G.A.2    Barton, D.H.R.3    Jacobs Jr., W.R.4    Sacchettini, J.C.5
  • 15
    • 67650732734 scopus 로고    scopus 로고
    • Triclosan resistance in clinical isolates of Acinetobacter baumannii
    • Chen Y, Pi B, Zhou H, Yu Y, Li L (2009) Triclosan resistance in clinical isolates of Acinetobacter baumannii. Journal of Medical Microbiology 58: 1086-1091.
    • (2009) Journal of Medical Microbiology , vol.58 , pp. 1086-1091
    • Chen, Y.1    Pi, B.2    Zhou, H.3    Yu, Y.4    Li, L.5
  • 17
    • 78751477224 scopus 로고    scopus 로고
    • Challenges of antibacterial discovery
    • Silver LL (2011) Challenges of antibacterial discovery. Clin Microbiol Rev 24: 71-109.
    • (2011) Clin Microbiol Rev , vol.24 , pp. 71-109
    • Silver, L.L.1
  • 18
    • 80051703609 scopus 로고    scopus 로고
    • Discovery research: The scientific challenge of finding new antibiotics
    • Livermore DM (2011) Discovery research: the scientific challenge of finding new antibiotics. Journal of Antimicrobial Chemotherapy 66: 1941-1944.
    • (2011) Journal of Antimicrobial Chemotherapy , vol.66 , pp. 1941-1944
    • Livermore, D.M.1
  • 22
    • 78049403603 scopus 로고    scopus 로고
    • The kalimantacin/batumin biosynthesis operon encodes a self-resistance isoform of the FabI bacterial target
    • Mattheus W, Masschelein J, Gao LJ, Herdewijn P, Landuyt B, et al. (2010) The kalimantacin/batumin biosynthesis operon encodes a self-resistance isoform of the FabI bacterial target. Chemistry and Biology 17: 1067-1071.
    • (2010) Chemistry and Biology , vol.17 , pp. 1067-1071
    • Mattheus, W.1    Masschelein, J.2    Gao, L.J.3    Herdewijn, P.4    Landuyt, B.5
  • 23
    • 0021347932 scopus 로고
    • Studies on fungal products. VII. The structures of meleagrin and 9-O-p-bromobenzoylmeleagrin
    • Kawai K, Nozawa K, Nakajima S, Iitaka Y (1984) Studies on fungal products. VII. The structures of meleagrin and 9-O-p-bromobenzoylmeleagrin. Chemical and Pharmaceutical Bulletin 32: 94-98. (Pubitemid 14195353)
    • (1984) Chemical and Pharmaceutical Bulletin , vol.32 , Issue.1 , pp. 94-98
    • Kawai, K.1    Nozawa, K.2    Nakajima, S.3    Iitaka, Y.4
  • 24
    • 24944448678 scopus 로고    scopus 로고
    • Fatty acid synthesis is a target for antibacterial activity of unsaturated fatty acids
    • DOI 10.1016/j.febslet.2005.08.028, PII S0014579305010124
    • Zheng CJ, Yoo JS, Lee TG, Cho HY, Kim YH, et al. (2005) Fatty acid synthesis is a target for antibacterial activity of unsaturated fatty acids. FEBS Letters 579: 5157-5162. (Pubitemid 41318085)
    • (2005) FEBS Letters , vol.579 , Issue.23 , pp. 5157-5162
    • Zheng, C.J.1    Yoo, J.-S.2    Lee, T.-G.3    Cho, H.-Y.4    Kim, Y.-H.5    Kim, W.-G.6
  • 25
    • 0029018327 scopus 로고
    • Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter
    • Guzman LM, Belin D, Carson MJ, Beckwith J (1995) Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter. Journal of Bacteriology 177: 4121-4130.
    • (1995) Journal of Bacteriology , vol.177 , pp. 4121-4130
    • Guzman, L.M.1    Belin, D.2    Carson, M.J.3    Beckwith, J.4
  • 26
    • 0037461276 scopus 로고    scopus 로고
    • Structure-activity studies of the inhibition of FabI, the enoyl reductase from Escherichia coli, by Triclosan: Kinetic analysis of mutant FabIs
    • DOI 10.1021/bi0300229
    • Sivaraman S, Zwahlen J, Bell AF, Hedstrom L, Tonge PJ (2003) Structureactivity studies of the inhibition of FabI, the enoyl reductase from Escherichia coli, by triclosan: kinetic analysis of mutant FabIs. Biochemistry 42: 4406-4413. (Pubitemid 36457608)
    • (2003) Biochemistry , vol.42 , Issue.15 , pp. 4406-4413
    • Sivaraman, S.1    Zwahlen, J.2    Bell, A.F.3    Hedstrom, L.4    Tonge, P.J.5
  • 28
    • 0037524693 scopus 로고
    • Isolation of radicicol from Penicillium Luteo-Aurantium, and Meleagrin, a new metabolite, from Penicillium Meleagrinum
    • Nozawa K, Nakajima S (1979) Isolation of radicicol from Penicillium Luteo-Aurantium, and Meleagrin, a new metabolite, from Penicillium Meleagrinum. Journal of Natural Products 42: 374-377.
    • (1979) Journal of Natural Products , vol.42 , pp. 374-377
    • Nozawa, K.1    Nakajima, S.2
  • 30
    • 26844550453 scopus 로고    scopus 로고
    • Identification of inhibitors of bacterial enoyl-acyl carrier protein reductase
    • Moir DT (2005) Identification of inhibitors of bacterial enoyl-acyl carrier protein reductase. Curr Drug Targets Infect Disord 5: 297-305.
    • (2005) Curr Drug Targets Infect Disord , vol.5 , pp. 297-305
    • Moir, D.T.1
  • 32
    • 3843101649 scopus 로고    scopus 로고
    • Evaluation of epigallocatechin gallate and related plant polyphenols as inhibitors of the FabG and FabI reductases of bacterial type II fatty-acid synthase
    • Zhang YM, Rock CO (2004) Evaluation of epigallocatechin gallate and related plant polyphenols as inhibitors of the FabG and FabI reductases of bacterial type II fatty-acid synthase. J Biol Chem 279: 30994-31001.
    • (2004) J Biol Chem , vol.279 , pp. 30994-31001
    • Zhang, Y.M.1    Rock, C.O.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.