R(+)-pulegone impairs Ca 2+ homeostasis and causes negative inotropism in mammalian myocardium

European Journal of Pharmacology

Volumn 672, Issue 1-3, 2011, Pages 135-142

  De Cerqueira, Sandra Valeria Santos ^a   Gondim, Antonio Nei Santana ^b,c   Roman Campos, Danilo ^b   Cruz, Jader Santos ^b   Passos, Amilton Gustavo Da Silva ^a   Lauton Santos, Sandra ^a   Lara, Aline ^b   Guatimosim, Silvia ^b   Conde Garcia, Eduardo Antonio ^a   De Oliveira, Evaleide Diniz ^a   De Vasconcelos, Carla Maria Lins ^a  

^a FEDERAL UNIVERSITY OF SERGIPE   (Brazil)

^b FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^c UNIVERSIDADE DO ESTADO DA BAHIA   (Brazil)

Author keywords

Calcium transient; Cardiac action potential; Contractility; L type calcium current; Potassium current; R(+) pulegone

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; CALCIUM CHANNEL L TYPE; CALCIUM CHLORIDE; CALCIUM ION; NIFEDIPINE; PULEGONE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM CURRENT; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; GUINEA PIG; HEART ATRIUM CONTRACTION; HEART MUSCLE; HEART MUSCLE CELL; HEART MUSCLE FIBER MEMBRANE POTENTIAL; HEART REPOLARIZATION; INOTROPISM; MALE; MOUSE; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL;

ACTION POTENTIALS; ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; FEMALE; GUINEA PIGS; HEART ATRIA; HOMEOSTASIS; INTRACELLULAR SPACE; MALE; MONOTERPENES; MYOCARDIAL CONTRACTION; MYOCARDIUM; POTASSIUM;

EID: 81255208444     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.09.186     Document Type: Article

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