Rearrangement or gem-difluorination of quinine and 9-epiquinine and their acetates in superacid

Tetrahedron

Volumn 61, Issue 8, 2005, Pages 2065-2073

  Debarge, Sébastien ^a   Thibaudeau, Sébastien ^a   Violeau, Bruno ^a   Martin Mingot, Agnès ^a   Jouannetaud, Marie Paule ^a   Jacquesy, Jean Claude ^a   Cousson, Alain ^b  

^a UMR 6514   (France)

^b CEA SACLAY   (France)

Author keywords

Cinchona alkaloids; Gem difluorination; Rearrangement; Superacid

Indexed keywords

ACETIC ACID DERIVATIVE; EPIQUININE; QUININE; QUININE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYCLIZATION; DRUG CONFORMATION; EPIMER; EPIMERIZATION; FLUORINATION; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; QUANTUM YIELD; REACTION ANALYSIS;

EID: 13444306402     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2004.12.045     Document Type: Article

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