-
1
-
-
84870672748
-
Is the current product safety assessment paradigm protective for epigenetic mechanisms?
-
Alyea RA, Moore NP, LeBaron MJ, Gollapudi BB, Rasoulpour RJ. 2012. Is the current product safety assessment paradigm protective for epigenetic mechanisms? J Pharmacol Toxicol Methods 66:207-214.
-
(2012)
J Pharmacol Toxicol Methods
, vol.66
, pp. 207-214
-
-
Alyea, R.A.1
Moore, N.P.2
LeBaron, M.J.3
Gollapudi, B.B.4
Rasoulpour, R.J.5
-
2
-
-
0032830639
-
Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
-
Amir RE, Van den Veyver IB, Wan M, Tran CQ, Francke U, Zoghbi HY. 1999. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat Genet 23:185-188.
-
(1999)
Nat Genet
, vol.23
, pp. 185-188
-
-
Amir, R.E.1
Van Den Veyver, I.B.2
Wan, M.3
Tran, C.Q.4
Francke, U.5
Zoghbi, H.Y.6
-
3
-
-
20344385787
-
Epigenetic transgenerational actions of endocrine disruptors and male fertility
-
Anway MD, Cupp AS, Uzumcu M, Skinner MK. 2005. Epigenetic transgenerational actions of endocrine disruptors and male fertility. Science 308:1466-1469.
-
(2005)
Science
, vol.308
, pp. 1466-1469
-
-
Anway, M.D.1
Cupp, A.S.2
Uzumcu, M.3
Skinner, M.K.4
-
4
-
-
33750607327
-
Transgenerational effect of the endocrine disruptor vinclozolin on male spermatogenesis
-
Anway MD, Memon MA, Uzumcu M, Skinner MK. 2006a. Transgenerational effect of the endocrine disruptor vinclozolin on male spermatogenesis. J Androl 27:868-879.
-
(2006)
J Androl
, vol.27
, pp. 868-879
-
-
Anway, M.D.1
Memon, M.A.2
Uzumcu, M.3
Skinner, M.K.4
-
5
-
-
33751533712
-
Endocrine disruptor vinclozolin induced epigenetic transgenerational adult-onset disease
-
Anway MD, Leathers C, Skinner MK. 2006b. Endocrine disruptor vinclozolin induced epigenetic transgenerational adult-onset disease. Endocrinology 147:5515-5523.
-
(2006)
Endocrinology
, vol.147
, pp. 5515-5523
-
-
Anway, M.D.1
Leathers, C.2
Skinner, M.K.3
-
6
-
-
84875165863
-
Epigenetic programming and reprogramming during development
-
Cantone I, Fisher AG. 2013. Epigenetic programming and reprogramming during development. Nat Struct Mol Biol 20:282-289.
-
(2013)
Nat Struct Mol Biol
, vol.20
, pp. 282-289
-
-
Cantone, I.1
Fisher, A.G.2
-
9
-
-
84896722786
-
-
EPA US. Reregistration Eligibility Decision (RED) Vinclozolin. EPA 738-R-00-023. Accessed on July 8, 2013.
-
EPA US. 2000. Reregistration Eligibility Decision (RED) Vinclozolin. EPA 738-R-00-023. Available at: http://www.epa.gov/opp00001/reregistration/REDs/2740red.pdf. Accessed on July 8, 2013.
-
(2000)
-
-
-
10
-
-
77955059818
-
What do we need to know prior to thinking about incorporating an epigenetic evaluation into safety assessments?
-
Goodman JI, Augustine KA, Cunnningham ML, Dixon D, Dragan YP, Falls JG, Rasoulpour RJ, Sills RC, Storer RD, Wolf DC, et al. 2010. What do we need to know prior to thinking about incorporating an epigenetic evaluation into safety assessments? Toxicol Sci 116:375-381.
-
(2010)
Toxicol Sci
, vol.116
, pp. 375-381
-
-
Goodman, J.I.1
Augustine, K.A.2
Cunnningham, M.L.3
Dixon, D.4
Dragan, Y.P.5
Falls, J.G.6
Rasoulpour, R.J.7
Sills, R.C.8
Storer, R.D.9
Wolf, D.C.10
-
11
-
-
84873544096
-
Vinclozolin treatment induces reproductive malformations and infertility in male rats when administered during sexual but not gonadal differentiation; However, the effects are not transmitted to the subsequent generations
-
Gray L, Furr J. 2008. Vinclozolin treatment induces reproductive malformations and infertility in male rats when administered during sexual but not gonadal differentiation; However, the effects are not transmitted to the subsequent generations. Biol Reprod 78:227-228.
-
(2008)
Biol Reprod
, vol.78
, pp. 227-228
-
-
Gray, L.1
Furr, J.2
-
12
-
-
0027937899
-
Developmental effects of an environmental antiandrogen: The fungicide vinclozolin alters sex differentiation of the male rat
-
Gray LE Jr, Ostby JS, Kelce WR. 1994. Developmental effects of an environmental antiandrogen: The fungicide vinclozolin alters sex differentiation of the male rat. Toxicol Appl Pharmacol 129:46-52.
-
(1994)
Toxicol Appl Pharmacol
, vol.129
, pp. 46-52
-
-
Gray Jr, L.E.1
Ostby, J.S.2
Kelce, W.R.3
-
13
-
-
0343962125
-
Environmental antiandrogens: Low doses of the fungicide vinclozolin alter sexual differentiation of the male rat
-
Gray LE Jr, Ostby J, Monosson E, Kelce WR. 1999. Environmental antiandrogens: Low doses of the fungicide vinclozolin alter sexual differentiation of the male rat. Toxicol Ind Health 15:48-64.
-
(1999)
Toxicol Ind Health
, vol.15
, pp. 48-64
-
-
Gray Jr, L.E.1
Ostby, J.2
Monosson, E.3
Kelce, W.R.4
-
15
-
-
84883484694
-
Chromatin and epigenetic features of long-range gene regulation
-
Harmston N, Lenhard B. 2013. Chromatin and epigenetic features of long-range gene regulation. Nucleic Acids Res 41:7185-7199.
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 7185-7199
-
-
Harmston, N.1
Lenhard, B.2
-
16
-
-
67349216233
-
Maternal exposure to anti-androgenic compounds, vinclozolin, flutamide and procymidone, has no effects on spermatogenesis and DNA methylation in male rats of subsequent generations
-
Inawaka K, Kawabe M, Takahashi S, Doi Y, Tomigahara Y, Tarui H, Abe J, Kawamura S, Shirai T. 2009. Maternal exposure to anti-androgenic compounds, vinclozolin, flutamide and procymidone, has no effects on spermatogenesis and DNA methylation in male rats of subsequent generations. Toxicol Appl Pharmacol 237:178-187.
-
(2009)
Toxicol Appl Pharmacol
, vol.237
, pp. 178-187
-
-
Inawaka, K.1
Kawabe, M.2
Takahashi, S.3
Doi, Y.4
Tomigahara, Y.5
Tarui, H.6
Abe, J.7
Kawamura, S.8
Shirai, T.9
-
17
-
-
77956191979
-
Epigenetics and chemical safety assessment
-
LeBaron MJ, Rasoulpour RJ, Klapacz J, Ellis-Hutchings RG, Hollnagel HM, Gollapudi BB. 2010. Epigenetics and chemical safety assessment. Mutat Res 705:83-95.
-
(2010)
Mutat Res
, vol.705
, pp. 83-95
-
-
LeBaron, M.J.1
Rasoulpour, R.J.2
Klapacz, J.3
Ellis-Hutchings, R.G.4
Hollnagel, H.M.5
Gollapudi, B.B.6
-
18
-
-
84875934940
-
The critical importance of epigenetics in autoimmunity
-
Lu QJ. 2013. The critical importance of epigenetics in autoimmunity. J Autoimmun 41:1-5.
-
(2013)
J Autoimmun
, vol.41
, pp. 1-5
-
-
Lu, Q.J.1
-
19
-
-
84866874968
-
Dioxin (TCDD) induces epigenetic transgenerational inheritance of adult onset disease and sperm epimutations
-
Manikkam M, Tracey R, Guerrero-Bosagna C, Skinner MK. 2012. Dioxin (TCDD) induces epigenetic transgenerational inheritance of adult onset disease and sperm epimutations. PLoS One 7:e46249.
-
(2012)
PLoS One
, vol.7
-
-
Manikkam, M.1
Tracey, R.2
Guerrero-Bosagna, C.3
Skinner, M.K.4
-
20
-
-
84872873280
-
Plastics derived endocrine disruptors (BPA, DEHP and DBP) induce epigenetic transgenerational inheritance of adult-onset disease and sperm epimutations
-
Manikkam M, Tracey R, Guerrero-Bosagna C, Skinner M. 2013. Plastics derived endocrine disruptors (BPA, DEHP and DBP) induce epigenetic transgenerational inheritance of adult-onset disease and sperm epimutations. PLoS One 8:e55387.
-
(2013)
PLoS One
, vol.8
-
-
Manikkam, M.1
Tracey, R.2
Guerrero-Bosagna, C.3
Skinner, M.4
-
21
-
-
33646456351
-
Evaluation of a two-generation reproduction toxicity study adding endpoints to detect endocrine disrupting activity using vinclozolin
-
Matsuura I, Saitoh T, Ashina M, Wako Y, Iwata H, Toyota N, Ishizuka Y, Namiki M, Hoshino N, Tsuchitani M. 2005. Evaluation of a two-generation reproduction toxicity study adding endpoints to detect endocrine disrupting activity using vinclozolin. J Toxicol Sci 30 Spec No.:163-188.
-
(2005)
J Toxicol Sci 30 Spec
, pp. 163-188
-
-
Matsuura, I.1
Saitoh, T.2
Ashina, M.3
Wako, Y.4
Iwata, H.5
Toyota, N.6
Ishizuka, Y.7
Namiki, M.8
Hoshino, N.9
Tsuchitani, M.10
-
22
-
-
77957935103
-
Linking cell signaling and the epigenetic machinery
-
Mohammad HP, Baylin SB. 2010. Linking cell signaling and the epigenetic machinery. Nat Biotechnol 28:1033-1038.
-
(2010)
Nat Biotechnol
, vol.28
, pp. 1033-1038
-
-
Mohammad, H.P.1
Baylin, S.B.2
-
23
-
-
84896711702
-
-
OECD. Chemicals testing guidelines. Available at: [accessed 18 July 2013].
-
OECD. 2013. Chemicals testing guidelines. Available at: http://www.oecd.org/env/ehs/testing/ [accessed 18 July 2013].
-
(2013)
-
-
-
24
-
-
79954517922
-
Epigenetic screening in product safety assessment: Are we there yet?
-
Rasoulpour RJ, LeBaron MJ, Ellis-Hutchings RG, Klapacz J, Gollapudi BB. 2011. Epigenetic screening in product safety assessment: Are we there yet? Toxicol Mech Methods 21:298-311.
-
(2011)
Toxicol Mech Methods
, vol.21
, pp. 298-311
-
-
Rasoulpour, R.J.1
LeBaron, M.J.2
Ellis-Hutchings, R.G.3
Klapacz, J.4
Gollapudi, B.B.5
-
25
-
-
44149128363
-
Vinclozolin-The lack of a transgenerational effect after oral maternal exposure during organogenesis
-
Schneider S, Kaufmann W, Buesen R, van Ravenzwaay B. 2008. Vinclozolin-The lack of a transgenerational effect after oral maternal exposure during organogenesis. Reprod Toxicol 25:352-360.
-
(2008)
Reprod Toxicol
, vol.25
, pp. 352-360
-
-
Schneider, S.1
Kaufmann, W.2
Buesen, R.3
van Ravenzwaay, B.4
-
26
-
-
84873528277
-
Vinclozolin-No transgenerational inheritance of anti-androgenic effects after maternal exposure during organogenesis via the intraperitoneal route
-
Schneider S, Marxfeld H, Groters S, Buesen R, van Ravenzwaay B. 2013. Vinclozolin-No transgenerational inheritance of anti-androgenic effects after maternal exposure during organogenesis via the intraperitoneal route. Reprod Toxicol 37:6-14.
-
(2013)
Reprod Toxicol
, vol.37
, pp. 6-14
-
-
Schneider, S.1
Marxfeld, H.2
Groters, S.3
Buesen, R.4
van Ravenzwaay, B.5
-
27
-
-
37349004800
-
What is an epigenetic transgenerational phenotype? F3 or F2
-
Skinner MK. 2008. What is an epigenetic transgenerational phenotype? F3 or F2. Reprod Toxicol 25:2-6.
-
(2008)
Reprod Toxicol
, vol.25
, pp. 2-6
-
-
Skinner, M.K.1
-
28
-
-
84875638440
-
Hydrocarbon (Jet Fuel JP-8) induces epigenetic transgenerational inheritance of adult-onset disease and sperm epimutations
-
Tracey R, Manikkam M, Guerrero-Bosagna C, Skinner M. 2013. Hydrocarbon (Jet Fuel JP-8) induces epigenetic transgenerational inheritance of adult-onset disease and sperm epimutations. Reprod Toxicol 36:104-116.
-
(2013)
Reprod Toxicol
, vol.36
, pp. 104-116
-
-
Tracey, R.1
Manikkam, M.2
Guerrero-Bosagna, C.3
Skinner, M.4
-
30
-
-
84896736281
-
-
WHO-JMPR. Vinclozolin
-
WHO-JMPR. 1995. Vinclozolin. pp 375-404.
-
(1995)
, pp. 375-404
-
-
-
31
-
-
0034068757
-
Characterization of the period of sensitivity of fetal male sexual development to vinclozolin
-
Wolf CJ, LeBlanc GA, Ostby JS, Gray LE Jr. 2000. Characterization of the period of sensitivity of fetal male sexual development to vinclozolin. Toxicol Sci 55:152-161.
-
(2000)
Toxicol Sci
, vol.55
, pp. 152-161
-
-
Wolf, C.J.1
LeBlanc, G.A.2
Ostby, J.S.3
Gray Jr, L.E.4
|