Oral Bisphenol A (BPA) given to rats at moderate doses is associated with erectile dysfunction, cavernosal lipofibrosis and alterations of global gene transcription

International Journal of Impotence Research

Volumn 26, Issue 2, 2014, Pages 67-75

  Kovanecz, I ^a,b   Gelfand, R ^a,c   Masouminia, M ^a   Gharib, S ^a   Segura, D ^a   Vernet, D ^a,c   Rajfer, J ^a,b   Li, D K ^d,e   Kannan, K ^f   Gonzalez Cadavid, N F ^a,b,c  

^a HARBOR UCLA MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CHARLES R DREW UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

^d STANFORD UNIVERSITY   (United States)

^e DIVISION OF RESEARCH   (United States)

^f WADSWORTH CENTER   (United States)

Author keywords

corporal veno occlusive dysfunction; epithelial mesenchymal transition; erectile dysfunction; fibrosis; microRNA

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; ALPHA SMOOTH MUSCLE ACTIN; CALPONIN; ESTRADIOL; MESSENGER RNA; MICRORNA; MICRORNA 200; MICRORNA 203; MICRORNA 205; TESTOSTERONE; UNCLASSIFIED DRUG; DNA NUCLEOTIDYLEXOTRANSFERASE; OCTAMER TRANSCRIPTION FACTOR 4;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BODY WEIGHT; CAVERNOSAL LIPOFIBROSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; ERECTILE DYSFUNCTION; ESTRADIOL BLOOD LEVEL; GENE MUTATION; GENETIC TRANSCRIPTION; IMMUNOHISTOCHEMISTRY; LIPID STORAGE; LONG TERM EXPOSURE; MALE; MEAN ARTERIAL PRESSURE; MYOFIBROBLAST; NICK END LABELING; NITRERGIC NERVE; NONHUMAN; PENIS DISEASE; PENIS ERECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TESTOSTERONE BLOOD LEVEL; TREATMENT DURATION; UPREGULATION; WESTERN BLOTTING; DNA MICROARRAY; DRUG MEGADOSE; ELECTROSTIMULATION; LOW DRUG DOSE; PENILE FIBROSIS; STEM CELL; TISSUE SECTION;

ADMINISTRATION, ORAL; ANIMALS; BENZHYDRYL COMPOUNDS; ELECTRIC STIMULATION; ERECTILE DYSFUNCTION; ESTRADIOL; ESTROGENS, NON-STEROIDAL; GENE EXPRESSION; MALE; MICRORNAS; MUSCLE, SMOOTH; PENIS; PHENOLS; RATS; RATS, INBRED F344; TESTOSTERONE;

EID: 84896547304     PISSN: 09559930     EISSN: 14765489     Source Type: Journal    
DOI: 10.1038/ijir.2013.37     Document Type: Article

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