Sheltering DNA in self-organizing, protein-only nano-shells as artificial viruses for gene delivery

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 10, Issue 3, 2014, Pages 535-541

  Unzueta, Ugutz ^a,b   Saccardo, Paolo ^a,b   Domingo Espín, Joan ^a,b   Cedano, Juan ^c   Conchillo Solé, Oscar ^a   García Fruitós, Elena ^a,b   Céspedes, María Virtudes ^b,d   Corchero, José Luis ^a,b   Daura, Xavier ^a,e   Mangues, Ramón ^b,d   Ferrer Miralles, Neus ^a,b   Villaverde, Antonio ^a,b   Vázquez, Esther ^a,b  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

^c UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^d HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

^e INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

Author keywords

Artificial viruses; Gene therapy; Nanoparticles; Protein building blocks; Self assembling

Indexed keywords

AMINO ACIDS; DNA; GENE THERAPY; GENE TRANSFER; MEDICAL NANOTECHNOLOGY; NANOPARTICLES; VIRUSES;

ARTIFICIAL VIRUS; BUILDING BLOCKES; ENDOSOMAL ESCAPES; FUNCTIONAL DOMAINS; PROTEIN NANOPARTICLES; SELF ORGANIZATIONS; SELF-ASSEMBLING; VIRUS-LIKE PARTICLES;

PROTEINS;

NANOSHELL; PLASMID DNA; POLYARGININE; POLYHISTIDINE; VIRUS PROTEIN;

ARTICLE; CONTROLLED STUDY; GENE FUSION; GENE TARGETING; NANOMEDICINE; NONHUMAN; NONVIRAL GENE THERAPY; PROTEIN ENGINEERING; PROTEIN PROTEIN INTERACTION; TARGET CELL; VIRUS GENE; VIRUS LIKE AGENT;

ARTIFICIAL VIRUSES; GENE THERAPY; NANOPARTICLES; PROTEIN BUILDING BLOCKS; SELF-ASSEMBLING;

AMINO ACID SEQUENCE; DNA; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; HELA CELLS; HISTIDINE; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NANOPARTICLES; PEPTIDES; PROTEINS;

EID: 84896542335     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2013.11.006     Document Type: Article

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