The effect of the neonatal Fc receptor on human IgG biodistribution in mice

mAbs

Volumn 6, Issue 2, 2014, Pages 502-508

  Chen, Nancy ^a   Wang, Weirong ^a   Fauty, Scott ^a   Fang, Yulin ^a   Hamuro, Lora ^a   Hussain, Azher ^a   Prueksaritanont, Thomayant ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Biodistribution; FcRn; IgG; Monoclonal antibody; Pharmacokinetics; Tissue distribution

Indexed keywords

FAT; FC RECEPTOR; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1 ANTIBODY; IODINE 125;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD; CONTROLLED STUDY; EXPOSURE; HOMEOSTASIS; ISOTOPE LABELING; MOUSE; MUSCLE; NONHUMAN; PINOCYTOSIS; PLASMA; PLASMA CLEARANCE; RADIOACTIVITY; ROOM TEMPERATURE; SKIN; TISSUE DISTRIBUTION; WILD TYPE;

BIODISTRIBUTION; FCRN; IGG; MONOCLONAL ANTIBODY; PHARMACOKINETICS; TISSUE DISTRIBUTION;

ADIPOSE TISSUE; ANIMALS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; IMMUNOGLOBULIN G; IODINE RADIOISOTOPES; LIVER; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, FC; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 84896515632     PISSN: 19420862     EISSN: 19420870     Source Type: Journal    
DOI: 10.4161/mabs.27765     Document Type: Article

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