Nonclassical major histocompatibility complex I-like Fc neonatal receptor (FcRn) expression in neonatal human tissues

Human Immunology

Volumn 72, Issue 12, 2011, Pages 1176-1187

  Cianga, Corina ^a   Cianga, Petru ^a,b   Plamadeala, Petru ^c   Amalinei, Cornelia ^a  

^a GRIGORE T POPA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^b University Hospital Sf Spiridon   (Romania)

^c Sf Maria Hospital   (Romania)

Author keywords

Catabolism; Endothelial cell; Epithelial cell; FcRn; IgG; Transcytosis

Indexed keywords

FC RECEPTOR; IMMUNOGLOBULIN G;

ARTICLE; CAPILLARY; CATABOLISM; CELL LINE; CONTROLLED STUDY; ENDOTHELIUM CELL; EPITHELIUM CELL; HUMAN; HUMAN TISSUE; MAJOR HISTOCOMPATIBILITY COMPLEX; MAMMARY GLAND; MEDICAL RECORD; NEWBORN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SKIN; SMOOTH MUSCLE FIBER;

ADULT; AMINO ACID SEQUENCE; ANTIBODIES; CADAVER; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; IMMUNITY, INNATE; IMMUNOGLOBULIN G; IMMUNOHISTOCHEMISTRY; INFANT, NEWBORN; MACROPHAGES; MOLECULAR SEQUENCE DATA; MYOCYTES, SMOOTH MUSCLE; NEURONS; ORGAN SPECIFICITY; PEPTIDES; RECEPTORS, FC; TRANSCYTOSIS;

EID: 81955164796     PISSN: 01988859     EISSN: 18791166     Source Type: Journal    
DOI: 10.1016/j.humimm.2011.08.020     Document Type: Article

References (44)

1. Brambell F.W.R. The Transmission of Passive Immunity from Mother to Young 1970, North-Holland, Amsterdam.
2. Montoyo H.P., Vaccaro C., Hafner M., Ober R.J., Mueller W., Ward E.S. Conditional deletion of the MHC class I-related receptor FcRn reveals the sites of IgG homeostasis in mice. Proc Natl Acad Sci USA 2009, 106:2788-2793.
3. Ward E.S., Zhou J., Ghetie V., Ober R.J. Evidence to support the cellular mechanism involved in serum IgG homeostasis in humans. Int Immunol 2003, 15:187-195.
4. Junghans R.P. Finally! The Brambell receptor (FcRB). Mediator of transmission of immunity and protection from catabolism for IgG. Immunol Res 1997, 16:29-57.
5. Ghetie V., Ward E.S. Multiple roles for the major histocompatibility complex class I-related receptor FcRn. Annu Rev Immunol 2000, 18:739-766.
6. Simister N.E., Story C.M., Chen H.L., Hunt J.S. An IgG-transporting Fc receptor expressed in the syncytiotrophoblast of human placenta. Eur J Immunol 1996, 26:1527-1531.
7. Israel E.J., Taylor S., Wu Z., Mizoguchi E., Blumberg R.S., Bhan A., et al. Expression of the neonatal Fc receptor, FcRn, on human intestinal epithelial cells. Immunology 1997, 92:69-74.
8. Zhu X., Meng G., Dickinson B.L., Li X., Mizoguchi E., Miao L., et al. MHC class I-related neonatal Fc receptor for IgG is functionally expressed in monocytes, intestinal macrophages, and dendritic cells. J Immunol 2001, 166:3266-3276.
9. Haymann J.-P., Levraud J.-P., Bouet S., Kappes V., Hagège J., Nguyen G., et al. Characterization and localization of the neonatal Fc receptor in adult human kidney. J Am Soc Nephrol 2000, 11:632-639.
10. Antohe F., Rǎdulescu L., Gafencu A., Ghetie V., Simionescu M. Expression of functionally active FcRn and the differentiated bidirectional transport of IgG in human placental endothelial cells. Hum Immunol 2001, 62:93-105.
11. Spiekermann G.M., Finn P.W., Ward E.S., Dumont J., Dickinson B.L., Blumberg R.S., et al. Receptor-mediated immunoglobulin G transport across mucosal barriers in adult life: functional expression of FcRn in the mammalian lung. J Exp Med 2002, 196:303-310.
12. Vidarsson G., Stemerding A.M., Stapleton N.M., Spliethoff S.E., Janssen H., Rebers F.E., et al. FcRn: an IgG receptor on phagocytes with a novel role in phagocytosis. Blood 2006, 108:3573-3579.
13. Cianga P., Cianga C., Cozma L., Ward E.S., Carasevici E. The MHC class I related Fc receptor, FcRn, is expressed in the epithelial cells of the human mammary gland. Hum Immunol 2003, 64:1152-1159.
14. Cauza K., Hinterhuber G., Dingelmaier-Hovorka R., Brugger K., Klosner G., Horvat R.W., et al. Expression of FcRn, the MHC class I-related receptor for IgG, in human keratinocytes. J Invest Dermatol 2005, 124:132-139.
15. Cianga P., Cianga C., Plamadeala P., Branisteanu D., Carasevici E. The neonatal Fc receptor (FcRn) expression in the human skin. Virchows Arch 2007, 451:859-860.
16. Cianga P., Medesan C., Richardson J.A., Ghetie V., Ward E.S. Identification and function of neonatal Fc receptor in mammary gland of lactating mice. Eur J Immunol 1999, 29:2515-2523.
17. Borvak J., Richardson J., Medesan C., Antohe F., Radu C., Simionescu M., et al. Functional expression of the MHC class I-related receptor, FcRn, in endothelial cells of mice. Int Immunol 1998, 10:1289-1298.
18. Moll R., Franke W.W., Schiller D.L., Geiger B., Krepler R. The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell 1982, 31:11-24.
19. Moll R. Cytokeratins as markers of differentiation in the diagnosis of epithelial tumors. Intermediate Filaments, Subcellular Biochemistry Vol. 31 1998, 205-262. Plenum Press, New York. H. Hermann, J.R. Harris (Eds.).
20. Dercksen M.W., Daams G.M., de Haas M., von dem Borne A.E.K.G., van der Schoot C.E. M10.2 characterization of the CD34 cluster. Leucocyte Typing V. White Cell Differentiation Antigens 1995, Oxford University Press, Oxford, UK. S.F. Schlossman (Ed.).
21. Kahn H.J., Marks A. A new monoclonal antibody, D2-40, for detection of lymphatic invasion in primary tumors. Lab Invest 2002, 82:1255-1257.
22. Pulford K.A.F., Rigney E.M., Micklem K.J., Jones M., Stross W.P., Gatter K.C., et al. KP1: a new monoclonal antibody that detects a monocyte/macrophage associated antigen in routinely processed tissue sections. J Clin Pathol 1989, 42:414-421.
23. Dickinson B.L., Badizadegan K., Wu Z., Ahouse J.C., Zhu X., Simister N.E., et al. Bidirectional FcRn-dependent IgG transport in a polarized human intestinal epithelial cell line. J Clin Invest 1999, 104:903-911.
24. Shah U., Dickinson B.L., Blumberg R.S., Simister N.E., Lencer W.I., Walker W.A. Distribution of the IgG Fc receptor, FcRn, in the human fetal intestine. Pediatr Res 2003, 53:295-301.
25. Young B., Lowe J.S., Stevens A., Heath J.W. Wheater's Functional Histology 2006, Churchill Livingstone Elsevier, New York. 5th ed.
26. Estienne V., Duthoit C., Reichert M., Praetor A., Carayon P., Hunziker W., et al. Androgen-dependent expression of FcgammaRIIB2 by thyrocytes from patients with autoimmune Graves' disease: a possible molecular clue for sex dependence of autoimmune disease. FASEB J 2002, 16:1087-1092.
27. Bukovsky A., Caudle M.R., Carson R.J., Gaytán F., Huleihel M., Kruse A., et al. Immune physiology in tissue regeneration and aging, tumor growth, and regenerative medicine. Aging (Albany NY) 2009, 1:157-181.
28. Blumberg R.S., Koss T., Story C.M., Barisani D., Polischuk J., Lipin A., et al. A major histocompatibility complex class I-related Fc receptor for IgG on rat hepatocytes. J Clin Invest 1995, 95:2397-2402.
29. Schlachetzki F., Zhu C., Pardridge W.M. Expression of the neonatal Fc receptor (FcRn) at the blood-brain barrier. J Neurochem 2002, 81:203-206.
30. Henderson L.A., Baynes J.W., Thorpe S.R. Identification of sites of IgG catabolism in rat. Arch Biochem Biophys 1984, 215:1-11.
31. Ghetie V., Ward E.S. Transcytosis and catabolism of antibody. Immunol Res 2002, 25:97-113.
32. Mak T.W., Saunders M.E. The Immune Response. Basic and Clinical Principles 2006, Elsevier, Oxford, UK.
33. Capano G., Bloch K.J., Schiffrin E.J., Dascoli J.A., Israel E.J., Harmatz P.R. Influence of the polyamine, spermidine, on the intestinal maturation and dietary antigen uptake in the neonatal rat. J Pediatr Gastroenterol Nutr 1994, 19:34-42.
34. Gill R.K., Mahmood S., Sodhi C.P., Nagpaul J.P., Mahmood A. IgG binding and expression of its receptor in rat intestine during postnatal development. Indian J Biochem Biophys 1999, 36:252-257.
35. Kim K.J., Fandy T.E., Lee V.H.K., Ann D.K., Borok Z., Crandall E.D. Net absorption of IgG via FcRn-mediated transcytosis across rat alveolar epithelial cell monolayers. Am J Physiol Lung Cell Mol Physiol 2004, 287:L616-L622.
36. Knee R.A., Hickey D.K., Beagley K.W., Jones R.C. Transport of IgG across the blood-luminal barrier of the male reproductive tract of the rat and the effect of estradiol administration on reabsorption of fluid and IgG by the epididymal ducts. Biol Reprod 2005, 73:688-694.
37. Liu X., Ye L., Christianson G.J., Yang J.Q., Roopenian D.C., Zhu X. NF-kappaB signaling regulates functional expression of the MHC class I-related neonatal Fc receptor for IgG via intronic binding sequences. J Immunol 2007, 179:2999-3011.
38. Liu X., Ye L., Bai Y., Mojidi H., Simister N.E., Zhu X. Activation of the JAK/STAT-1 signaling pathway by IFN-γ can down-regulate functional expression of the MHC class I-related neonatal Fc receptor for IgG. J Immunol 2008, 181:449-463.
39. Kacskovics I., Wu Z., Simister N.E., Frenyó L.V., Hammarström L. Cloning and characterization of the bovine MHC class I-like Fc receptor. J Immunol 2000, 164:1889-1897.
40. Waldmann T.A., Strober W. Metabolism of immunoglobulins. Prog Allergy 1969, 13:1-110.
41. Roberts D.M., Guenthert M., Rodewald R.J. Isolation and characterization of the Fc receptor from the fetal yolk sac of the rat. J Cell Biol 1990, 111:1867-1876.
42. Mehta P.D., Isaacs C.E., Coyle P.K. Immunoglobulin G subclasses in human colostrum and milk. Immunology of Milk and the Neonate 1991, Plenum Press, New York. J. Mestecki, C. Blair, P.L. Ogra (Eds.).
43. Arend W.P., Silverblatt F.J. Serum disappearance and catabolism of homologous immunoglobulin fragments in rats. Clin Exp Immunol 1975, 22:502-513.
44. Ghetie V., Hubbard J.G., Kim J.K., Tsen M.F., Lee Y., Ward E.S. Abnormally short serum half-lives of IgG in beta2-microglobulin-deficient mice. Eur J Immunol 1996, 26:690-696.