-
1
-
-
84876720410
-
Power of metabolomics in diagnosis and biomarker discovery of hepatocellular carcinoma
-
Wang X, Zhang A, Sun H. Power of metabolomics in diagnosis and biomarker discovery of hepatocellular carcinoma. Hepatology 2013;57:2072-2077.
-
(2013)
Hepatology
, vol.57
, pp. 2072-2077
-
-
Wang, X.1
Zhang, A.2
Sun, H.3
-
2
-
-
79953147370
-
A perspective on cancer cell metastasis
-
Chaffer CL, Weinberg RA. A perspective on cancer cell metastasis. Science 2011;331:1559-1564.
-
(2011)
Science
, vol.331
, pp. 1559-1564
-
-
Chaffer, C.L.1
Weinberg, R.A.2
-
3
-
-
0030457019
-
Intrahepatic metastases in hepatocellular carcinoma: the role of the portal vein as an efferent vessel
-
Mitsunobu M, Toyosaka A, Oriyama T, Okamoto E, Nakao N. Intrahepatic metastases in hepatocellular carcinoma: the role of the portal vein as an efferent vessel. Clin Exp Metastasis 1996;14:520-529.
-
(1996)
Clin Exp Metastasis
, vol.14
, pp. 520-529
-
-
Mitsunobu, M.1
Toyosaka, A.2
Oriyama, T.3
Okamoto, E.4
Nakao, N.5
-
4
-
-
0030698373
-
Morphological study of vascular dissemination in a metastatic hepatocellular carcinoma model in the monkey
-
Lindsay CK, Sinha CC, Thorgeirsson UP. Morphological study of vascular dissemination in a metastatic hepatocellular carcinoma model in the monkey. Hepatology 1997;26:1209-1215.
-
(1997)
Hepatology
, vol.26
, pp. 1209-1215
-
-
Lindsay, C.K.1
Sinha, C.C.2
Thorgeirsson, U.P.3
-
5
-
-
84873050284
-
Regulatory networks defining EMT during cancer initiation and progression
-
De Craene B, Berx G. Regulatory networks defining EMT during cancer initiation and progression. Nat Rev Cancer 2013;13:97-110.
-
(2013)
Nat Rev Cancer
, vol.13
, pp. 97-110
-
-
De Craene, B.1
Berx, G.2
-
6
-
-
33749024777
-
Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis
-
Christiansen JJ, Rajasekaran AK. Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis. Cancer Res 2006;66:8319-8326.
-
(2006)
Cancer Res
, vol.66
, pp. 8319-8326
-
-
Christiansen, J.J.1
Rajasekaran, A.K.2
-
7
-
-
0142250911
-
The human ribonucleotide reductase subunit hRRM2 complements p53R2 in response to UV-induced DNA repair in cells with mutant p53
-
Zhou B, Liu X, Mo X, Xue L, Darwish D, Qiu W, et al. The human ribonucleotide reductase subunit hRRM2 complements p53R2 in response to UV-induced DNA repair in cells with mutant p53. Cancer Res 2003;63:6583-6594.
-
(2003)
Cancer Res
, vol.63
, pp. 6583-6594
-
-
Zhou, B.1
Liu, X.2
Mo, X.3
Xue, L.4
Darwish, D.5
Qiu, W.6
-
8
-
-
0034594978
-
A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage
-
Tanaka H, Arakawa H, Yamaguchi T, Shiraishi K, Fukuda S, Matsui K, et al. A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage. Nature 2000;404:42-49.
-
(2000)
Nature
, vol.404
, pp. 42-49
-
-
Tanaka, H.1
Arakawa, H.2
Yamaguchi, T.3
Shiraishi, K.4
Fukuda, S.5
Matsui, K.6
-
9
-
-
78449268580
-
Expression of ribonucleotide reductase M2 subunit in gastric cancer and effects of RRM2 inhibition in vitro
-
Morikawa T, Hino R, Uozaki H, Maeda D, Ushiku T, Shinozaki A, et al. Expression of ribonucleotide reductase M2 subunit in gastric cancer and effects of RRM2 inhibition in vitro. Hum Pathol 2010;41:1742-1748.
-
(2010)
Hum Pathol
, vol.41
, pp. 1742-1748
-
-
Morikawa, T.1
Hino, R.2
Uozaki, H.3
Maeda, D.4
Ushiku, T.5
Shinozaki, A.6
-
10
-
-
1542742114
-
RNA interference targeting the M2 subunit of ribonucleotide reductase enhances pancreatic adenocarcinoma chemosensitivity to gemcitabine
-
Duxbury MS, Ito H, Zinner MJ, Ashley SW, Whang EE. RNA interference targeting the M2 subunit of ribonucleotide reductase enhances pancreatic adenocarcinoma chemosensitivity to gemcitabine. Oncogene 2004;23:1539-1548.
-
(2004)
Oncogene
, vol.23
, pp. 1539-1548
-
-
Duxbury, M.S.1
Ito, H.2
Zinner, M.J.3
Ashley, S.W.4
Whang, E.E.5
-
11
-
-
80054722409
-
Expression status of ribonucleotide reductase small subunits hRRM2/p53R2 as prognostic biomarkers in stage I and II non-small cell lung cancer
-
Hsu NY, Wu JY, Liu X, Yen Y, Chen CY, Chou MC, et al. Expression status of ribonucleotide reductase small subunits hRRM2/p53R2 as prognostic biomarkers in stage I and II non-small cell lung cancer. Anticancer Res 2011;31:3475-3481.
-
(2011)
Anticancer Res
, vol.31
, pp. 3475-3481
-
-
Hsu, N.Y.1
Wu, J.Y.2
Liu, X.3
Yen, Y.4
Chen, C.Y.5
Chou, M.C.6
-
12
-
-
79955492402
-
Ribonucleotide reductase small subunit M2B prognoses better survival in colorectal cancer
-
Liu X, Lai L, Wang X, Xue L, Leora S, Wu J, et al. Ribonucleotide reductase small subunit M2B prognoses better survival in colorectal cancer. Cancer Res 2011;71:3202-3213.
-
(2011)
Cancer Res
, vol.71
, pp. 3202-3213
-
-
Liu, X.1
Lai, L.2
Wang, X.3
Xue, L.4
Leora, S.5
Wu, J.6
-
13
-
-
33745711788
-
Expression of p53R2 is related to prognosis in patients with esophageal squamous cell carcinoma
-
Okumura H, Natsugoe S, Yokomakura N, Kita Y, Matsumoto M, Uchikado Y, et al. Expression of p53R2 is related to prognosis in patients with esophageal squamous cell carcinoma. Clin Cancer Res 2006;12:3740-3745.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3740-3745
-
-
Okumura, H.1
Natsugoe, S.2
Yokomakura, N.3
Kita, Y.4
Matsumoto, M.5
Uchikado, Y.6
-
14
-
-
84866290837
-
MEK2 regulates ribonucleotide reductase activity through functional interaction with ribonucleotide reductase small subunit p53R2
-
Piao C, Youn CK, Jin M, Yoon SP, Chang IY, Lee JH, et al. MEK2 regulates ribonucleotide reductase activity through functional interaction with ribonucleotide reductase small subunit p53R2. Cell Cycle 2012;11:3237-3249.
-
(2012)
Cell Cycle
, vol.11
, pp. 3237-3249
-
-
Piao, C.1
Youn, C.K.2
Jin, M.3
Yoon, S.P.4
Chang, I.Y.5
Lee, J.H.6
-
15
-
-
67349265769
-
Ribonucleotide reductase small subunit p53R2 suppresses MEK-ERK activity by binding to ERK kinase 2
-
Piao C, Jin M, Kim HB, Lee SM, Amatya PN, Hyun JW, et al. Ribonucleotide reductase small subunit p53R2 suppresses MEK-ERK activity by binding to ERK kinase 2. Oncogene 2009;28:2173-2184.
-
(2009)
Oncogene
, vol.28
, pp. 2173-2184
-
-
Piao, C.1
Jin, M.2
Kim, H.B.3
Lee, S.M.4
Amatya, P.N.5
Hyun, J.W.6
-
16
-
-
80052015345
-
Hypoxia-inducible factor 1 alpha-activated angiopoietin-like protein 4 contributes to tumor metastasis via vascular cell adhesion molecule-1/integrin beta1 signaling in human hepatocellular carcinoma
-
Li H, Ge C, Zhao F, Yan M, Hu C, Jia D, et al. Hypoxia-inducible factor 1 alpha-activated angiopoietin-like protein 4 contributes to tumor metastasis via vascular cell adhesion molecule-1/integrin beta1 signaling in human hepatocellular carcinoma. Hepatology 2011;54:910-919.
-
(2011)
Hepatology
, vol.54
, pp. 910-919
-
-
Li, H.1
Ge, C.2
Zhao, F.3
Yan, M.4
Hu, C.5
Jia, D.6
-
17
-
-
43749112192
-
Anti-cancer effects of JKA97 are associated with its induction of cell apoptosis via a Bax-dependent and p53-independent pathway
-
Luo W, Liu J, Li J, Zhang D, Liu M, Addo JK, et al. Anti-cancer effects of JKA97 are associated with its induction of cell apoptosis via a Bax-dependent and p53-independent pathway. J Biol Chem 2008;283:8624-8633.
-
(2008)
J Biol Chem
, vol.283
, pp. 8624-8633
-
-
Luo, W.1
Liu, J.2
Li, J.3
Zhang, D.4
Liu, M.5
Addo, J.K.6
-
18
-
-
77957735670
-
Oncolytic adenovirus SG600-IL24 selectively kills hepatocellular carcinoma cell lines
-
Xue XB, Xiao CW, Zhang H, Lu AG, Gao W, Zhou ZQ, et al. Oncolytic adenovirus SG600-IL24 selectively kills hepatocellular carcinoma cell lines. World J Gastroenterol 2010;16:4677-4684.
-
(2010)
World J Gastroenterol
, vol.16
, pp. 4677-4684
-
-
Xue, X.B.1
Xiao, C.W.2
Zhang, H.3
Lu, A.G.4
Gao, W.5
Zhou, Z.Q.6
-
19
-
-
66349119527
-
NORE1A tumor suppressor candidate modulates p21CIP1 via p53
-
Calvisi DF, Donninger H, Vos MD, Birrer MJ, Gordon L, Leaner V, et al. NORE1A tumor suppressor candidate modulates p21CIP1 via p53. Cancer Res 2009;69:4629-4637.
-
(2009)
Cancer Res
, vol.69
, pp. 4629-4637
-
-
Calvisi, D.F.1
Donninger, H.2
Vos, M.D.3
Birrer, M.J.4
Gordon, L.5
Leaner, V.6
-
20
-
-
79951842968
-
p53R2 inhibits the proliferation of human cancer cells in association with cell-cycle arrest
-
Zhang K, Wu J, Wu X, Wang X, Wang Y, Zhou N, et al. p53R2 inhibits the proliferation of human cancer cells in association with cell-cycle arrest. Mol Cancer Ther 2011;10:269-278.
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 269-278
-
-
Zhang, K.1
Wu, J.2
Wu, X.3
Wang, X.4
Wang, Y.5
Zhou, N.6
-
21
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery JP, Acloque H, Huang RY, Nieto MA. Epithelial-mesenchymal transitions in development and disease. Cell 2009;139:871-890.
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
22
-
-
27844461512
-
Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3′ kinase/AKT pathways
-
Larue L, Bellacosa A. Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3′ kinase/AKT pathways. Oncogene 2005;24:7443-7454.
-
(2005)
Oncogene
, vol.24
, pp. 7443-7454
-
-
Larue, L.1
Bellacosa, A.2
-
23
-
-
0035199914
-
The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling
-
Virolle T, Adamson ED, Baron V, Birle D, Mercola D, Mustelin T, et al. The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling. Nat Cell Biol 2001;3:1124-1128.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 1124-1128
-
-
Virolle, T.1
Adamson, E.D.2
Baron, V.3
Birle, D.4
Mercola, D.5
Mustelin, T.6
-
24
-
-
0029975798
-
E-cadherin is involved in the intrahepatic metastasis of hepatocellular carcinoma
-
Osada T, Sakamoto M, Ino Y, Iwamatsu A, Matsuno Y, Muto T, et al. E-cadherin is involved in the intrahepatic metastasis of hepatocellular carcinoma. Hepatology 1996;24:1460-1467.
-
(1996)
Hepatology
, vol.24
, pp. 1460-1467
-
-
Osada, T.1
Sakamoto, M.2
Ino, Y.3
Iwamatsu, A.4
Matsuno, Y.5
Muto, T.6
-
25
-
-
0038155087
-
Transcriptional repressor snail and progression of human hepatocellular carcinoma
-
Sugimachi K, Tanaka S, Kameyama T, Taguchi K, Aishima S, Shimada M, et al. Transcriptional repressor snail and progression of human hepatocellular carcinoma. Clin Cancer Res 2003;9:2657-2664.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 2657-2664
-
-
Sugimachi, K.1
Tanaka, S.2
Kameyama, T.3
Taguchi, K.4
Aishima, S.5
Shimada, M.6
-
26
-
-
84866868120
-
Exome sequencing of hepatitis B virus-associated hepatocellular carcinoma
-
Huang J, Deng Q, Wang Q, Li KY, Dai JH, Li N, et al. Exome sequencing of hepatitis B virus-associated hepatocellular carcinoma. Nat Genet 2012;44:1117-1121.
-
(2012)
Nat Genet
, vol.44
, pp. 1117-1121
-
-
Huang, J.1
Deng, Q.2
Wang, Q.3
Li, K.Y.4
Dai, J.H.5
Li, N.6
-
27
-
-
78951475020
-
p53 and its mutants in tumor cell migration and invasion
-
Muller PA, Vousden KH, Norman JC. p53 and its mutants in tumor cell migration and invasion. J Cell Biol 2011;192:209-218.
-
(2011)
J Cell Biol
, vol.192
, pp. 209-218
-
-
Muller, P.A.1
Vousden, K.H.2
Norman, J.C.3
-
28
-
-
0037051690
-
Expression and mutation analyses of P53R2, a newly identified p53 target for DNA repair in human gastric carcinoma
-
Byun DS, Chae KS, Ryu BK, Lee MG, Chi SG. Expression and mutation analyses of P53R2, a newly identified p53 target for DNA repair in human gastric carcinoma. Int J Cancer 2002;98:718-723.
-
(2002)
Int J Cancer
, vol.98
, pp. 718-723
-
-
Byun, D.S.1
Chae, K.S.2
Ryu, B.K.3
Lee, M.G.4
Chi, S.G.5
-
29
-
-
0033556443
-
Tumor suppressor PTEN inhibition of cell invasion, migration, and growth: differential involvement of focal adhesion kinase and p130Cas
-
Tamura M, Gu J, Takino T, Yamada KM. Tumor suppressor PTEN inhibition of cell invasion, migration, and growth: differential involvement of focal adhesion kinase and p130Cas. Cancer Res 1999;59:442-449.
-
(1999)
Cancer Res
, vol.59
, pp. 442-449
-
-
Tamura, M.1
Gu, J.2
Takino, T.3
Yamada, K.M.4
-
30
-
-
79955110863
-
Loss of phosphatase and tensin homolog enhances cell invasion and migration through AKT/Sp-1 transcription factor/matrix metalloproteinase 2 activation in hepatocellular carcinoma and has clinicopathologic significance
-
Sze KM, Wong KL, Chu GK, Lee JM, Yau TO, Ng IO. Loss of phosphatase and tensin homolog enhances cell invasion and migration through AKT/Sp-1 transcription factor/matrix metalloproteinase 2 activation in hepatocellular carcinoma and has clinicopathologic significance. Hepatology 2011;53:1558-1569.
-
(2011)
Hepatology
, vol.53
, pp. 1558-1569
-
-
Sze, K.M.1
Wong, K.L.2
Chu, G.K.3
Lee, J.M.4
Yau, T.O.5
Ng, I.O.6
-
31
-
-
78651401992
-
Snail2 is an essential mediator of Twist1-induced epithelial mesenchymal transition and metastasis
-
Casas E, Kim J, Bendesky A, Ohno-Machado L, Wolfe CJ, Yang J. Snail2 is an essential mediator of Twist1-induced epithelial mesenchymal transition and metastasis. Cancer Res 2011;71:245-254.
-
(2011)
Cancer Res
, vol.71
, pp. 245-254
-
-
Casas, E.1
Kim, J.2
Bendesky, A.3
Ohno-Machado, L.4
Wolfe, C.J.5
Yang, J.6
-
32
-
-
0037086277
-
The SLUG zinc-finger protein represses E-cadherin in breast cancer
-
Hajra KM, Chen DY, Fearon ER. The SLUG zinc-finger protein represses E-cadherin in breast cancer. Cancer Res 2002;62:1613-1618.
-
(2002)
Cancer Res
, vol.62
, pp. 1613-1618
-
-
Hajra, K.M.1
Chen, D.Y.2
Fearon, E.R.3
-
33
-
-
84888199808
-
Slug promoted vasculogenic mimicry in hepatocellular carcinoma
-
Sun D, Sun B, Liu T, Zhao X, Che N, Gu Q, et al. Slug promoted vasculogenic mimicry in hepatocellular carcinoma. J Cell Mol Med 2013;17:1038-1047.
-
(2013)
J Cell Mol Med
, vol.17
, pp. 1038-1047
-
-
Sun, D.1
Sun, B.2
Liu, T.3
Zhao, X.4
Che, N.5
Gu, Q.6
-
35
-
-
44449144396
-
Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis
-
Yang J, Weinberg RA. Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev Cell 2008;14:818-829.
-
(2008)
Dev Cell
, vol.14
, pp. 818-829
-
-
Yang, J.1
Weinberg, R.A.2
-
36
-
-
84864080019
-
The epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasion
-
Fenouille N, Tichet M, Dufies M, Pottier A, Mogha A, Soo JK, et al. The epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasion. PLoS One 2012;7:e40378.
-
(2012)
PLoS One
, vol.7
-
-
Fenouille, N.1
Tichet, M.2
Dufies, M.3
Pottier, A.4
Mogha, A.5
Soo, J.K.6
-
37
-
-
0042166135
-
Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools
-
Kimura T, Takeda S, Sagiya Y, Gotoh M, Nakamura Y, Arakawa H. Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools. Nat Genet 2003;34:440-445.
-
(2003)
Nat Genet
, vol.34
, pp. 440-445
-
-
Kimura, T.1
Takeda, S.2
Sagiya, Y.3
Gotoh, M.4
Nakamura, Y.5
Arakawa, H.6
-
38
-
-
77955464721
-
Akt/PKB suppresses DNA damage processing and checkpoint activation in late G2
-
Xu N, Hegarat N, Black EJ, Scott MT, Hochegger H, Gillespie DA. Akt/PKB suppresses DNA damage processing and checkpoint activation in late G2. J Cell Biol 2010;190:297-305.
-
(2010)
J Cell Biol
, vol.190
, pp. 297-305
-
-
Xu, N.1
Hegarat, N.2
Black, E.J.3
Scott, M.T.4
Hochegger, H.5
Gillespie, D.A.6
-
39
-
-
12344310089
-
Akt and 14-3-3eta regulate Miz1 to control cell-cycle arrest after DNA damage
-
Wanzel M, Kleine-Kohlbrecher D, Herold S, Hock A, Berns K, Park J, et al. Akt and 14-3-3eta regulate Miz1 to control cell-cycle arrest after DNA damage. Nat Cell Biol 2005;7:30-41.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 30-41
-
-
Wanzel, M.1
Kleine-Kohlbrecher, D.2
Herold, S.3
Hock, A.4
Berns, K.5
Park, J.6
|