Wound healing activity of the leaf extracts and deoxyelephantopin isolated from Elephantopus scaber Linn.

Indian Journal of Pharmacology

Volumn 37, Issue 4, 2005, Pages 238-242

  Singh, S D J ^a   Krishna, V ^b   Mankani, K L ^a   Manjunatha, B K ^c   Vidya, S M ^c   Manohara, Y N ^a  

^a NATIONAL COLLEGE OF PHARMACY   (India)

^b KUVEMPU UNIVERSITY   (India)

^c SRNM National College of Applied Sciences   (India)

Author keywords

Elephant's foot; Wound models

Indexed keywords

ALCOHOL; COLLAGEN; DEOXYELEPHANTOPIN; ELEPHANTOPUS SCABER EXTRACT; PLANT EXTRACT; SESQUITERPENE LACTONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTERACEAE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG ISOLATION; EPITHELIZATION; GRANULATION TISSUE; INFLAMMATORY INFILTRATE; NONHUMAN; RAT; SKIN EPITHELIUM; SKIN INCISION; TENSILE STRENGTH; TISSUE SECTION; WOUND CONTRACTION; WOUND HEALING;

EID: 23844490049     PISSN: 02537613     EISSN: None     Source Type: Journal    
DOI: 10.4103/0253-7613.16570     Document Type: Article

References (24)

1. Nadakarni AK. Indian Materia Medica. Mumbai: Dhootapapeshwar Prakashan Ltd.; 1954.
2. Kirtikar KR, Basu BD. Indian Medicinal Plants. Delhi: Periodical Experts Book Agency; 1991.
3. Chopra RN, Nayar SL, Chopra IC. Glossary of Indian Medicinal Plants. Delhi: CSIR; 1956.
4. Vaidya BG. Nighantu Adarsha. Varanasi: Chackhamba Bharathi Academi; 1999.
5. Paul Pui-Hay But, Po-Ming Hon, Hui Cao, TW.Dominic Chan, Bo-Mu Wu, Thomas CW.Mak, Chun-Tao Che. Sesquiterpene lactones from Elephantopus scaber. Phytochem 1997;44:113.
6. De-Silva LB, Herath WHMW, Jennings RC, Mahendran M, Wannigamma GE. A new sesquiterpene lactone from Elephantopus scaber. Phytochem 1982;21:1173.
7. Poli A, Nicolan M, Simoes CM, Nicolan RM, Zanin M. Preliminary pharmacological evaluation of crude whole plant extracts of Elephantopus scaber. Part I: In vivo studies. J Ethnopharmacol 1992;37:71-6.
8. Tsai CC, Lin CC. Anti inflammatory effects of Taiwan folk medicine 'Teng Khia U' on carrageenan and adjuvant induced paw edema in rats. J Ethnopharmacol 1999;64:85-9.
9. Lin CC, Tsai CC, Yen MH. The evaluation of Hepatoprotective effects of Taiwan folk medicine 'Teng Khia U'. J Ethnopharmacol 1995;45:113-23.
10. Jean Bruneton. Pharmacognosy and Phytochemistry. New York: Intercept Ltd; 1999.
11. Giordano OS, Guerreiro E, Pestchanker MJ, Guzman J, Pas D, Guardia T. The gastric cytoprotective effect of several sesquiterpene lactones. J Nat Prod 1990;53:803-9.
12. Manjunatha BK, Krishna V, Pullaiah T. Flora of Davanagare District. Karnataka. New Delhi: Regency Publications; 2003.
13. Ghosh MN. Fundamentals of Experimental Pharmacology. Kolkata: Scientific Book Agency; 1984.
14. Mukherjee PK. Quality control Herbal Drugs. New Delhi: Business Horizons; 2002.
15. Morton JJP, Malone MH. Evaluation of vulnery activity of open wound procedure in rats. Arch Int Pharmacodyn Ther 1972;196:117-26.
16. Ehrlich HP, Hunt TK. The effect of cortisone and anabolic steroids on the tensile strength of healing wounds. Ann Surg 1968;167:117.
17. Lee KH. Studies on the mechanism of action of salicylate retardation of wound healing by aspirin. J Pharmaceut Sci 1968;57:1042.
18. Kanai L Mukherjee. Medical laboratory Technology. New Delhi: Tata McGraw-Hill Ltd.; New Delhi 2000.
19. Fischer NH, Lu T, Cantrell CL, Castaneda Acoata J, Quijano L, Franzblau SG. Antimycobacterial evaluation of germacranolides. Phytochemistry 1998;49:559-64.
20. Barrero AF, Oltra JE, Alvarez M, Raslan DS, Saude DA, Akssira M. New sources and anti fungal activity of sesquiterpene lactones. Fitoterapia 2000;71:60-4.
21. Rekka EA, Angeliki P. Investigation of the effect of chamazulene on lipid peroxidation and free radical processes. Res Comm Mol Pathol Pharmacol 1966;92:361.
22. Hatapakki BC, Hukkeri V, Patil DN, Chavan MJ. Wound healing activity of aerial parts of Merremia tridentata. Indian Drugs 2004;41:532.
23. Mankani KL, Krishna V, Singh JSD, Manjunath BK, Vidya SM, Manohara YN. Evaluation of wound healing activity of the stem bark of Diospyros cordifolia. Indian Drugs 2004;41:628.
24. Khan M, Patil PA, Shobha JC. Influence of Bryophyllum pinnatum leaf extract on wound healing in albino rats. J Natural Remedies 2004;4:41.