메뉴 건너뛰기




Volumn 19, Issue 1, 2015, Pages 117-126

Effect of interleukin-1β on ICAM-1 expression of dental pulp cells: role of PI3K/Akt, MEK/ERK, and cyclooxygenase

Author keywords

Cyclooxygenase; Dental pulp cells; Inflammation; Intercellular adhesion molecule 1 (ICAM 1); Interleukin 1 ; MEK ERK; PI3K Akt

Indexed keywords

2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; ACETYLSALICYLIC ACID; CHROMONE DERIVATIVE; CYCLOOXYGENASE 2; EUGENOL; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE; MORPHOLINE DERIVATIVE; PHOSPHATIDYLINOSITOL 3 KINASE;

EID: 84896415109     PISSN: 14326981     EISSN: 14363771     Source Type: Journal    
DOI: 10.1007/s00784-014-1227-0     Document Type: Article
Times cited : (23)

References (54)
  • 2
    • 34250217079 scopus 로고    scopus 로고
    • Immunohistochemical evaluation of endothelial cell adhesion molecules in human dental pulp: effects of tooth preparation and adhesive application
    • PID: 17324377
    • Bagis B, Atilla P, Cakar N, Hasanreisoglu H (2007) Immunohistochemical evaluation of endothelial cell adhesion molecules in human dental pulp: effects of tooth preparation and adhesive application. Arch Oral Biol 52:705–711
    • (2007) Arch Oral Biol , vol.52 , pp. 705-711
    • Bagis, B.1    Atilla, P.2    Cakar, N.3    Hasanreisoglu, H.4
  • 3
    • 67650022833 scopus 로고    scopus 로고
    • The effect of BisGMA on cyclooxygenase-2 expression, PGE2 production and cytotoxicity via reactive oxygen species- and MEK/ERK-dependent and -independent pathways
    • PID: 19467701
    • Chang MC, Lin LD, Chan CP, Chang HH, Chen LI, Lin HJ, Yeh HW, Tseng WY, Lin PS, Lin CC, Jeng JH (2009) The effect of BisGMA on cyclooxygenase-2 expression, PGE2 production and cytotoxicity via reactive oxygen species- and MEK/ERK-dependent and -independent pathways. Biomaterials 30:4070–4077
    • (2009) Biomaterials , vol.30 , pp. 4070-4077
    • Chang, M.C.1    Lin, L.D.2    Chan, C.P.3    Chang, H.H.4    Chen, L.I.5    Lin, H.J.6    Yeh, H.W.7    Tseng, W.Y.8    Lin, P.S.9    Lin, C.C.10    Jeng, J.H.11
  • 4
    • 78751641324 scopus 로고    scopus 로고
    • Caries induced cytokine network in the odontoblast layer of human teeth
    • Horst OV, Horst JA, Samudrala R, Dale BA (2012) Caries induced cytokine network in the odontoblast layer of human teeth. BMC Immunol 12:9
    • (2012) BMC Immunol , vol.12 , pp. 9
    • Horst, O.V.1    Horst, J.A.2    Samudrala, R.3    Dale, B.A.4
  • 5
    • 34250185370 scopus 로고    scopus 로고
    • Update on the adaptive immune responses of the dental pulp
    • PID: 17804311
    • Hahn CL, Liewehr FR (2007) Update on the adaptive immune responses of the dental pulp. J Endod 33:773–781
    • (2007) J Endod , vol.33 , pp. 773-781
    • Hahn, C.L.1    Liewehr, F.R.2
  • 6
    • 34248138845 scopus 로고    scopus 로고
    • Innate immune responses of the dental pulp to caries
    • PID: 17509400
    • Hahn CL, Liewehr FR (2007) Innate immune responses of the dental pulp to caries. J Endod 33:643–651
    • (2007) J Endod , vol.33 , pp. 643-651
    • Hahn, C.L.1    Liewehr, F.R.2
  • 7
    • 0026456388 scopus 로고
    • Tissue pressure and blood flow in pulpal inflammation
    • PID: 1508897
    • Heyeraas KJ, Kvinnsland I (1992) Tissue pressure and blood flow in pulpal inflammation. Proc Finn Dent Soc 88(Suppl 1):393–401
    • (1992) Proc Finn Dent Soc , vol.88 , pp. 393-401
    • Heyeraas, K.J.1    Kvinnsland, I.2
  • 8
    • 18544410947 scopus 로고
    • Effects of selected inflammatory mediators on blood flow and vascular permeability in the dental pulp
    • PID: 1508895
    • Kim S, Liu M, Simchon S, Dorscher-Kim JE (1992) Effects of selected inflammatory mediators on blood flow and vascular permeability in the dental pulp. Proc Finn Dent Soc 88(Suppl 1):387–392
    • (1992) Proc Finn Dent Soc , vol.88 , pp. 387-392
    • Kim, S.1    Liu, M.2    Simchon, S.3    Dorscher-Kim, J.E.4
  • 11
    • 47249109331 scopus 로고    scopus 로고
    • Interleukin-1beta up-regulates tumor necrosis factor receptors in the mouse airways
    • PID: 18515164
    • Cardell LO, Uddman R, Zhang Y, Adner M (2008) Interleukin-1beta up-regulates tumor necrosis factor receptors in the mouse airways. Pulm Pharmacol Ther 21:675–681
    • (2008) Pulm Pharmacol Ther , vol.21 , pp. 675-681
    • Cardell, L.O.1    Uddman, R.2    Zhang, Y.3    Adner, M.4
  • 13
    • 84864545087 scopus 로고    scopus 로고
    • Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
    • PID: 22850787
    • Dinarello CA, Simon A, Van Der Meer JW (2012) Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases. Nat Rev Drug Discov 11:633–652
    • (2012) Nat Rev Drug Discov , vol.11 , pp. 633-652
    • Dinarello, C.A.1    Simon, A.2    Van Der Meer, J.W.3
  • 15
  • 16
    • 79955681780 scopus 로고    scopus 로고
    • IL-1 receptor/Toll-like receptor signaling in infection, inflammation, stress and neurodegeneration couples hyperexcitability and seizures
    • PID: 21473909
    • Vezzani A, Maroso M, Balosso S, Sanchez MA, Bartfai T (2011) IL-1 receptor/Toll-like receptor signaling in infection, inflammation, stress and neurodegeneration couples hyperexcitability and seizures. Brain Behav Immun 25:1281–1289
    • (2011) Brain Behav Immun , vol.25 , pp. 1281-1289
    • Vezzani, A.1    Maroso, M.2    Balosso, S.3    Sanchez, M.A.4    Bartfai, T.5
  • 17
    • 77952502966 scopus 로고    scopus 로고
    • Interleukin-1 receptor antagonist (IL-1Ra) and IL-1Ra producing mesenchymal stem cells as modulators of diabetogenesis
    • PID: 19845478
    • Volarevic V, Al-Qahtani A, Arsenijevic N, Pajovic S, Lukic ML (2010) Interleukin-1 receptor antagonist (IL-1Ra) and IL-1Ra producing mesenchymal stem cells as modulators of diabetogenesis. Autoimmunity 43:255–263
    • (2010) Autoimmunity , vol.43 , pp. 255-263
    • Volarevic, V.1    Al-Qahtani, A.2    Arsenijevic, N.3    Pajovic, S.4    Lukic, M.L.5
  • 18
    • 84892866814 scopus 로고    scopus 로고
    • The interleukin-1 receptor family
    • PID: 24246227
    • Boraschi D, Tagliabue A (2013) The interleukin-1 receptor family. Semin Immunol 25:394–407
    • (2013) Semin Immunol , vol.25 , pp. 394-407
    • Boraschi, D.1    Tagliabue, A.2
  • 19
    • 34447324371 scopus 로고    scopus 로고
    • The expanding family of interleukin-1 cytokines and their role in destructive inflammatory disorders
    • PID: 17590166
    • Barksby HE, Lea SR, Preshaw PM, Taylor JJ (2007) The expanding family of interleukin-1 cytokines and their role in destructive inflammatory disorders. Clin Exp Immunol 149:217–225
    • (2007) Clin Exp Immunol , vol.149 , pp. 217-225
    • Barksby, H.E.1    Lea, S.R.2    Preshaw, P.M.3    Taylor, J.J.4
  • 20
    • 84891715379 scopus 로고    scopus 로고
    • Rheumatoid arthritis and Alzheimer’s disease: genetic and apigenetic links in inflammatory regulation
    • PID: 23272690
    • Ferraccioli G, Carbonella A, Gremese E, Alivernini S (2012) Rheumatoid arthritis and Alzheimer’s disease: genetic and apigenetic links in inflammatory regulation. Discov Med 14:379–388
    • (2012) Discov Med , vol.14 , pp. 379-388
    • Ferraccioli, G.1    Carbonella, A.2    Gremese, E.3    Alivernini, S.4
  • 21
  • 23
    • 84856555643 scopus 로고    scopus 로고
    • Carboxylesterase expression in human dental pulp cells: role in regulation of BisGMA-induced prostanoid production and cytotoxicity
    • PID: 21951919
    • Chang MC, Lin LD, Chuang FH, Chan CP, Wang TM, Lee JJ, Jeng PY, Tseng WY, Lin HJ, Jeng JH (2012) Carboxylesterase expression in human dental pulp cells: role in regulation of BisGMA-induced prostanoid production and cytotoxicity. Acta Biomater 8:1380–1387
    • (2012) Acta Biomater , vol.8 , pp. 1380-1387
    • Chang, M.C.1    Lin, L.D.2    Chuang, F.H.3    Chan, C.P.4    Wang, T.M.5    Lee, J.J.6    Jeng, P.Y.7    Tseng, W.Y.8    Lin, H.J.9    Jeng, J.H.10
  • 24
    • 0030275530 scopus 로고    scopus 로고
    • Immunohistochemical demonstration of prostaglandins E2, F2 alpha, and 6-keto-prostaglandin F1 alpha in rat dental pulp with experimentally induced inflammation
    • PID: 9198415
    • Miyauchi M, Takata T, Ito H, Ogawa I, Kobayashi J, Nikai H, Ijuhin N (1996) Immunohistochemical demonstration of prostaglandins E2, F2 alpha, and 6-keto-prostaglandin F1 alpha in rat dental pulp with experimentally induced inflammation. J Endod 22:600–602
    • (1996) J Endod , vol.22 , pp. 600-602
    • Miyauchi, M.1    Takata, T.2    Ito, H.3    Ogawa, I.4    Kobayashi, J.5    Nikai, H.6    Ijuhin, N.7
  • 25
    • 33748324703 scopus 로고    scopus 로고
    • Cytokine-induced prostaglandin E2 production and cyclooxygenase-2 expression in dental pulp cells: downstream calcium signalling via activation of prostaglandin EP receptor
    • PID: 16948668
    • Chang MC, Chen YJ, Tai TF, Tai MR, Li MY, Tsai YL, Lan WH, Jeng JH (2006) Cytokine-induced prostaglandin E2 production and cyclooxygenase-2 expression in dental pulp cells: downstream calcium signalling via activation of prostaglandin EP receptor. Int Endod J 39:819–826
    • (2006) Int Endod J , vol.39 , pp. 819-826
    • Chang, M.C.1    Chen, Y.J.2    Tai, T.F.3    Tai, M.R.4    Li, M.Y.5    Tsai, Y.L.6    Lan, W.H.7    Jeng, J.H.8
  • 26
    • 40149092792 scopus 로고    scopus 로고
    • IL-1beta stimulates urokinase-type plasminogen activator expression and secretion in human dental pulp cells
    • PID: 18202522
    • Kamio N, Hashizume H, Nakao S, Matsushima K, Sugiya H (2007) IL-1beta stimulates urokinase-type plasminogen activator expression and secretion in human dental pulp cells. Biomed Res 28:315–322
    • (2007) Biomed Res , vol.28 , pp. 315-322
    • Kamio, N.1    Hashizume, H.2    Nakao, S.3    Matsushima, K.4    Sugiya, H.5
  • 27
    • 63649122607 scopus 로고    scopus 로고
    • Prostaglandin F2alpha-induced interleukin-8 production in human dental pulp cells is associated with MEK/ERK/CREB signaling
    • PID: 19345795
    • Chang MC, Chang HH, Lee MY, Lin CC, Yeh HW, Yang TT, Lin PS, Jeng JH (2009) Prostaglandin F2alpha-induced interleukin-8 production in human dental pulp cells is associated with MEK/ERK/CREB signaling. J Endod 35:508–512
    • (2009) J Endod , vol.35 , pp. 508-512
    • Chang, M.C.1    Chang, H.H.2    Lee, M.Y.3    Lin, C.C.4    Yeh, H.W.5    Yang, T.T.6    Lin, P.S.7    Jeng, J.H.8
  • 28
    • 0034351170 scopus 로고    scopus 로고
    • Prostaglandin E2 predominantly induces production of hepatocyte growth factor/scatter factor in human dental pulp in acute inflammation
    • PID: 10728976
    • Ohnishi T, Suwa M, Oyama T, Arakaki N, Torii M, Daikuhara Y (2000) Prostaglandin E2 predominantly induces production of hepatocyte growth factor/scatter factor in human dental pulp in acute inflammation. J Dent Res 79:748–755
    • (2000) J Dent Res , vol.79 , pp. 748-755
    • Ohnishi, T.1    Suwa, M.2    Oyama, T.3    Arakaki, N.4    Torii, M.5    Daikuhara, Y.6
  • 30
    • 0028135089 scopus 로고
    • Regulation of intercellular adhesion molecule-1 gene expression involves multiple mRNA stabilization mechanisms: effects of interferon-gamma and phorbol myristate acetate
    • PID: 7919377
    • Ohh M, Smith CA, Carpenito C, Takei F (1994) Regulation of intercellular adhesion molecule-1 gene expression involves multiple mRNA stabilization mechanisms: effects of interferon-gamma and phorbol myristate acetate. Blood 84:2632–2639
    • (1994) Blood , vol.84 , pp. 2632-2639
    • Ohh, M.1    Smith, C.A.2    Carpenito, C.3    Takei, F.4
  • 31
    • 0022574146 scopus 로고
    • Induction by IL-1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1)
    • PID: 3086451
    • Dustin MC, Rothlein R, Bhan AK, Dinarello CA, Springer TA (1986) Induction by IL-1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). J Immunol 137:245–254
    • (1986) J Immunol , vol.137 , pp. 245-254
    • Dustin, M.C.1    Rothlein, R.2    Bhan, A.K.3    Dinarello, C.A.4    Springer, T.A.5
  • 32
    • 3242796635 scopus 로고    scopus 로고
    • Soluble intercellular adhesion molecule-1 (sICAM-1): an overview
    • PID: 15319166
    • Witkowska AM, Borawska MH (2004) Soluble intercellular adhesion molecule-1 (sICAM-1): an overview. Eur Cytokine Netw 15:91–98
    • (2004) Eur Cytokine Netw , vol.15 , pp. 91-98
    • Witkowska, A.M.1    Borawska, M.H.2
  • 33
    • 66949136652 scopus 로고    scopus 로고
    • ICAM-1 signaling in endothelial cells
    • PID: 19307690
    • Lawson C, Wolf S (2009) ICAM-1 signaling in endothelial cells. Pharmacol Rep 61:22–32
    • (2009) Pharmacol Rep , vol.61 , pp. 22-32
    • Lawson, C.1    Wolf, S.2
  • 34
    • 0035514524 scopus 로고    scopus 로고
    • Cell adhesion molecules, leukocyte trafficking, and strategies to reduce leukocyte infiltration
    • PID: 11817056
    • Radi ZA, Kehrli ME, Ackermann MR (2001) Cell adhesion molecules, leukocyte trafficking, and strategies to reduce leukocyte infiltration. J Vet Intern Med 15:516–529
    • (2001) J Vet Intern Med , vol.15 , pp. 516-529
    • Radi, Z.A.1    Kehrli, M.E.2    Ackermann, M.R.3
  • 35
    • 0035403373 scopus 로고    scopus 로고
    • Interleukin-1beta regulation of adhesion molecules on human gingival and periodontal ligament fibroblasts
    • PID: 11495133
    • Joe BH, Borke JL, Keskintepe M, Hanes PJ, Mailhot JM, Singh BB (2001) Interleukin-1beta regulation of adhesion molecules on human gingival and periodontal ligament fibroblasts. J Periodontol 72:865–870
    • (2001) J Periodontol , vol.72 , pp. 865-870
    • Joe, B.H.1    Borke, J.L.2    Keskintepe, M.3    Hanes, P.J.4    Mailhot, J.M.5    Singh, B.B.6
  • 36
  • 37
    • 84861202805 scopus 로고    scopus 로고
    • Regulation of vascular cell adhesion molecule-1 in dental pulp cells by interleukin-1beta: the role of prostanoids
    • PID: 22595111
    • Chang MC, Lin LD et al (2012) Regulation of vascular cell adhesion molecule-1 in dental pulp cells by interleukin-1beta: the role of prostanoids. J Endod 38:774–779
    • (2012) J Endod , vol.38 , pp. 774-779
    • Chang, M.C.1    Lin, L.D.2
  • 39
    • 18844396688 scopus 로고    scopus 로고
    • Protocatechuic aldehydes suppress TNF-alpha-induced ICAM-1 and VCAM-1 expression in human umbilical vein endothelial cells
    • PID: 15878704
    • Zhou Z, Liu Y, Miao AD, Wang SQ (2005) Protocatechuic aldehydes suppress TNF-alpha-induced ICAM-1 and VCAM-1 expression in human umbilical vein endothelial cells. Eur J Pharmacol 513:1–8
    • (2005) Eur J Pharmacol , vol.513 , pp. 1-8
    • Zhou, Z.1    Liu, Y.2    Miao, A.D.3    Wang, S.Q.4
  • 40
    • 84883055477 scopus 로고    scopus 로고
    • Toxicity of areca nut ingredients: activation of Chk1/Chk2, induction of cell cycle arrest and regulation of MMP-9 and TIMPs production in SAS epithelial cells
    • PID: 22907745
    • Chang MC, Chan CP, Wang WT, Chang BE, Lee JJ, Tseng SK, Yeung SY, Hahn LJ, Jeng JH (2013) Toxicity of areca nut ingredients: activation of Chk1/Chk2, induction of cell cycle arrest and regulation of MMP-9 and TIMPs production in SAS epithelial cells. Head Neck 35:1295–1302
    • (2013) Head Neck , vol.35 , pp. 1295-1302
    • Chang, M.C.1    Chan, C.P.2    Wang, W.T.3    Chang, B.E.4    Lee, J.J.5    Tseng, S.K.6    Yeung, S.Y.7    Hahn, L.J.8    Jeng, J.H.9
  • 41
    • 0033775796 scopus 로고    scopus 로고
    • Interleukin-1/Toll receptor family members: receptor structure and signal transduction pathways
    • PID: 11054272
    • Daun JM, Fenton MJ (2000) Interleukin-1/Toll receptor family members: receptor structure and signal transduction pathways. J Interferon Cytokine Res 20:843–855
    • (2000) J Interferon Cytokine Res , vol.20 , pp. 843-855
    • Daun, J.M.1    Fenton, M.J.2
  • 42
    • 0031685273 scopus 로고    scopus 로고
    • Expression of the mRNA for types I and II interleukin-1 receptors in dental tissues of mice during tooth development
    • PID: 9744996
    • Xu LX, Kukita T, Yu H, Nakano Y, Koga T (1998) Expression of the mRNA for types I and II interleukin-1 receptors in dental tissues of mice during tooth development. Calcif Tissue Int 63:351–356
    • (1998) Calcif Tissue Int , vol.63 , pp. 351-356
    • Xu, L.X.1    Kukita, T.2    Yu, H.3    Nakano, Y.4    Koga, T.5
  • 43
    • 70349860107 scopus 로고    scopus 로고
    • Sensory pulpal nerve fibres and trigeminal ganglion neurons express IL-1RI: a potential mechanism for development of inflammatory hyperalgesia
    • PID: 19732182
    • Bletsa A, Fristad I, Berggreen E (2009) Sensory pulpal nerve fibres and trigeminal ganglion neurons express IL-1RI: a potential mechanism for development of inflammatory hyperalgesia. Int Endod J 42:978–986
    • (2009) Int Endod J , vol.42 , pp. 978-986
    • Bletsa, A.1    Fristad, I.2    Berggreen, E.3
  • 44
    • 0033914492 scopus 로고    scopus 로고
    • Interleukin-1 receptor signaling rather than that of tumor necrosis factor is critical in protecting the host from the severe consequences of a polymicrobe anaerobic infection
    • PID: 10899881
    • Graves DT, Chen CP, Douville C, Jiang Y (2000) Interleukin-1 receptor signaling rather than that of tumor necrosis factor is critical in protecting the host from the severe consequences of a polymicrobe anaerobic infection. Infect Immun 68:4746–4751
    • (2000) Infect Immun , vol.68 , pp. 4746-4751
    • Graves, D.T.1    Chen, C.P.2    Douville, C.3    Jiang, Y.4
  • 45
    • 0031947309 scopus 로고    scopus 로고
    • Vascular endothelium of human dental pulp expresses diverse adhesion molecules for leukocyte emigration
    • PID: 9661300
    • Sawa Y, Yoshida S, Shibata KI, Suzuki M, Mukaida A (1998) Vascular endothelium of human dental pulp expresses diverse adhesion molecules for leukocyte emigration. Tissue Cell 30:281–291
    • (1998) Tissue Cell , vol.30 , pp. 281-291
    • Sawa, Y.1    Yoshida, S.2    Shibata, K.I.3    Suzuki, M.4    Mukaida, A.5
  • 46
    • 57649212046 scopus 로고    scopus 로고
    • An immunohistochemical evaluation of cell adhesion molecules in human dental pulp after tooth preparation and application of temporary luting cements
    • PID: 19101496
    • Bagis B et al (2009) An immunohistochemical evaluation of cell adhesion molecules in human dental pulp after tooth preparation and application of temporary luting cements. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 107:137–144
    • (2009) Oral Surg Oral Med Oral Pathol Oral Radiol Endod , vol.107 , pp. 137-144
    • Bagis, B.1
  • 47
    • 84855871525 scopus 로고    scopus 로고
    • Monocyte-mediated immune defense against murine Listeria monocytogenes infection
    • PID: 22244581
    • Serbina NV, Shi C, Pamer EG (2012) Monocyte-mediated immune defense against murine Listeria monocytogenes infection. Adv Immunol 113:119–134
    • (2012) Adv Immunol , vol.113 , pp. 119-134
    • Serbina, N.V.1    Shi, C.2    Pamer, E.G.3
  • 48
    • 33947492733 scopus 로고    scopus 로고
    • Cardiovascular disease in diabetic nephropathy patients: cell adhesion molecules as potential markers
    • PID: 17315603
    • Wu T, McGrath KCY, Death AK (2005) Cardiovascular disease in diabetic nephropathy patients: cell adhesion molecules as potential markers. Vasc Health Risk Manag 1:309–316
    • (2005) Vasc Health Risk Manag , vol.1 , pp. 309-316
    • Wu, T.1    McGrath, K.C.Y.2    Death, A.K.3
  • 49
    • 33746287145 scopus 로고    scopus 로고
    • Cytokine-induced monocyte adhesion to endothelial cells involves platelet-activating factor: suppression by conjugated linoleic acid
    • PID: 16829183
    • Sneddon AA et al (2006) Cytokine-induced monocyte adhesion to endothelial cells involves platelet-activating factor: suppression by conjugated linoleic acid. Biochim Biophys Acta 1761:793–801
    • (2006) Biochim Biophys Acta , vol.1761 , pp. 793-801
    • Sneddon, A.A.1
  • 50
    • 6344278016 scopus 로고    scopus 로고
    • The 15-deoxy-delta12,14-prostaglandin J2 inhibits the inflammatory response in primary rat astrocytes via down-regulating multiple steps in phosphatidylinositol 3-kinase-Akt-NF-kappaB-p300 pathway independent of peroxisome proliferator-activated receptor gamma
    • PID: 15470065
    • Giri S et al (2004) The 15-deoxy-delta12,14-prostaglandin J2 inhibits the inflammatory response in primary rat astrocytes via down-regulating multiple steps in phosphatidylinositol 3-kinase-Akt-NF-kappaB-p300 pathway independent of peroxisome proliferator-activated receptor gamma. J Immunol 173:5196–5208
    • (2004) J Immunol , vol.173 , pp. 5196-5208
    • Giri, S.1
  • 51
    • 84879772484 scopus 로고    scopus 로고
    • Carvedilol decrease IL-1beta and TNF-alpha, inhibits MMP-2, MMP-9, COX-2, and RANKL expression, and up-regulates OPG in a rat model of periodontitis
    • PID: 23843954
    • de Araujo Junior RF et al (2013) Carvedilol decrease IL-1beta and TNF-alpha, inhibits MMP-2, MMP-9, COX-2, and RANKL expression, and up-regulates OPG in a rat model of periodontitis. PLoS One 8:e66391
    • (2013) PLoS One , vol.8 , pp. e66391
    • de Araujo Junior, R.F.1
  • 52
    • 34548336803 scopus 로고    scopus 로고
    • Hydroxychavicol, a novel betel leaf component, inhibits platelet aggregation by suppression of cyclooxygenase, thromboxane production and calcium mobilization
    • PID: 17641677
    • Chang MC, Uang BJ, Tsai CY et al (2007) Hydroxychavicol, a novel betel leaf component, inhibits platelet aggregation by suppression of cyclooxygenase, thromboxane production and calcium mobilization. Br J Pharmacol 152:73–82
    • (2007) Br J Pharmacol , vol.152 , pp. 73-82
    • Chang, M.C.1    Uang, B.J.2    Tsai, C.Y.3
  • 53
    • 34848818869 scopus 로고    scopus 로고
    • Mutations in cryopyrin: bypassing roadblocks in the caspase 1 inflammasome for interleukin-1beta secretion and disease activity
    • PID: 17763412
    • Dinarello CA (2007) Mutations in cryopyrin: bypassing roadblocks in the caspase 1 inflammasome for interleukin-1beta secretion and disease activity. Arthritis Rheum 56:2817–2822
    • (2007) Arthritis Rheum , vol.56 , pp. 2817-2822
    • Dinarello, C.A.1
  • 54
    • 0034943516 scopus 로고    scopus 로고
    • Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes
    • PID: 11435451
    • Tilley SL, Coffman TM, Koller BH (2001) Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes. J Clin Invest 108:15–23
    • (2001) J Clin Invest , vol.108 , pp. 15-23
    • Tilley, S.L.1    Coffman, T.M.2    Koller, B.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.