Prostaglandin F2α-Induced Interleukin-8 Production in Human Dental Pulp Cells Is Associated With MEK/ERK Signaling

Journal of Endodontics

Volumn 35, Issue 4, 2009, Pages 508-512

  Chang, Mei Chi ^a   Chang, Hsiao Hua ^b   Lee, Mon Ying ^b   Lin, Chiu Chun ^c   Yeh, Hung Wei ^b   Yang, Ting Ting ^b   Lin, Po Shuen ^b   Tseng, Wan Yu ^b   Jeng, Jiiang Huei ^b  

^a CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Dental pulp; interleukin 8; mitogen activated protein kinase kinase; PGF2 ; signaling

Indexed keywords

1,3 BUTADIENE DERIVATIVE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 9 (TETRAHYDRO 2 FURYL) ADENINE; 9-(TETRAHYDRO-2-FURYL)-ADENINE; ACTIVATING TRANSCRIPTION FACTOR 1; ADENINE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DRUG DERIVATIVE; INTERLEUKIN 1BETA; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; NITRILE; PROSTAGLANDIN F2 ALPHA; PROTEIN KINASE INHIBITOR;

ARTICLE; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; METABOLISM; PHYSIOLOGY; PULPITIS; SIGNAL TRANSDUCTION; TOOTH PULP;

ACTIVATING TRANSCRIPTION FACTOR 1; ADENINE; BUTADIENES; CELLS, CULTURED; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DENTAL PULP; DINOPROST; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; INTERLEUKIN-1BETA; INTERLEUKIN-8; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NITRILES; PROTEIN KINASE INHIBITORS; PULPITIS;

EID: 63649122607     PISSN: 00992399     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joen.2008.12.023     Document Type: Article

References (39)

1. Hosoya S., Matsushima K., Ohbayashi E., Yamazaki M., Shibata Y., and Abiko Y. Stimulation of interleukin-1β-independent interleukin-6 production in human dental pulp cells by lipopolysaccharide. Biol Mol Med 59 (1996) 138-143
2. Jontell M., Okiji T., Dahlgren U., and Bergenholtz G. Immune defense mechanisms of the dental pulp. Crit Rev Oral Biol Med 9 (1998) 179-200
3. Lee S.K., Min K.S., Kim Y.B., et al. Mechanical stress activates proinflammatory cytokines and antioxidant defense enzymes in human dental pulp cells. J Endod 34 (2008) 1364-1369
4. Langeland K. Tissue response to dental caries. Endod Dent Traumatol 3 (1987) 149-171
5. Hirafuji M., Satoh S., and Ogura Y. Prostaglandins in rat pulp tissue. J Dent Res 59 (1983) 1535-1540
6. Hahn C.L., and Liewehr F.R. Innate immune responses of the dental pulp to caries. J Endod 33 (2007) 643-651
7. Huang G.T., Lee H.W., Lee H.S., et al. localization of substance P-induced upregulated interleukin-8 expression in human dental pulp explants. Int Endod J 41 (2008) 100-107
8. Hedbom E., and Hauselmann H.J. Molecular aspects of pathogenesis in osteoarthritis: the role of inflammation. Cell Mol Life Sci 59 (2002) 45-53
9. Bos C.L., Richel D.J., Ritsema T., Peppelenbosch M.P., and Versteeg H.H. Prostanoids and prostanoid receptors in signal transduction. J Biochem Cell Biol 36 (2003) 1187-1205
10. Noguchi K., Endo H., Kondo H., and Ishikawa I. Prostaglandin F2α upregulates interleukin-6 production in human gingival fibroblasts. J Periodontal Res 36 (2001) 80-87
11. Noguchi K., Tominaga Y., Matsushita K., et al. Upregulation of matrix metalloproteinase-1 production by prostaglandin F2alpha in human gingival fibroblasts. J Periodontal Res 36 (2001) 334-339
12. Basu S. Novel cyclooxygenase-catalyzed bioactive prostaglandin F2alpha from physiology to new principles in inflammation. Med Res Rev 27 (2007) 435-468
13. Watanabe T., Nakao A., Emerling D., et al. Prostaglandin F2 alpha enhances tyrosine phosphorylation and DNA synthesis through phospholipase C-coupled receptor via Ca(2+)-dependent intracellular pathway in NIH3T3 cells. J Biol Chem 269 (1994) 17619-17625
14. Pierce K.L., Bailey T.J., Hoyer P.B., Gil D.W., Woodward D.F., and Regan J.W. Cloning of a carboxyl-terminal isoform of the prostanoid FP receptor. J Biol Chem 272 (1997) 883-887
15. Cohen J.S., Reader A., Fertel R., Beck M., and Meyers W.J. A radioimmunoassay determination of the concentrations of prostaglandins E2 and F2 in painful and asymptomatic human dental pulps. J Endod 11 (1985) 330-335
16. Miyauchi M., Takata T., Ito H., et al. Immunohistochemical demonstration of prostaglandin E2, F2alpha and 6-keto-prostaglandin F1 alpha in rat dental pulp with experimentally induced inflammation. J Endod 22 (1996) 600-602
17. Huang G.T., Potente A.P., Kim J.W., Chugal N., and Zhang X. Increased interleukin-8 expression in inflamed human dental pulps. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 88 (1999) 214-220
18. Chang H.H., Guo M.K., Kasten F.H., et al. Stimulation of glutathione depletion, ROS production and cell cycle arrest of dental pulp cells and gingival epithelial cells by HEMA. Biomaterials 26 (2005) 745-753
19. Chang M.C., Tai M.R., Tai T.F., et al. Prostaglandin EP receptor signaling and calcium mobilization in dental pulp cells. Int Endod J 39 (2006) 819-826
20. Tai T.F., Chan C.P., Lin C.C., Chen L.I., Chang M.C., and Jeng J.H. TGF-beta2 regulates growth and differentiation of pulp cells via ALK-5/Smad2/3. J Endod 34 (2008) 427-432
21. Chang M.C., Wu H.L., Lee J.J., et al. The induction of prostaglandin E2 production, interleukin-6 production, cell cycle arrest, and cytotoxicity in primary oral keratinocytes and KB cancer cells by areca nut ingredients is differentially regulated by MEK/ERK activation. J Biol Chem 279 (2004) 50676-50683
22. Jeng J.H., Wang Y.J., Chiang B.L., et al. Roles of keratinocyte inflammation in oral cancer: regulating the prostaglandin E2, interleukin-6 and TNF-alpha production of oral epithelial cells by areca nut extract and arecoline. Carcinogenesis 24 (2003) 1301-1315
23. Lockwood C.J., Toti P., Arcuri F., et al. Mechanisms of abruption-induced premature rupture of the fetal membranes: thrombin-enhanced interleukin-8 expression in term decidua. Am J Pathol 167 (2005) 1443-1449
24. Martinez Z.R., Naruishi K., Yamashiro K., et al. Gene profiles during root canal treatment in experimental rat periapical lesions. J Endod 23 (2007) 936-943
25. Menezes R., Garlet T.P., Trombone A.P., et al. The potential role of suppressors of cytokine signaling in the attenuation of inflammatory reaction and alveolar bone loss associated with apical periodontitis. J Endod 24 (2008) 1480-1484
26. Chang Y.C., Yang S.F., Huang F.M., Liu C.M., Tai K.W., and Hsieh Y.S. Proinflammatory cytokines induce cyclooxygenase-2 mRNA and protein expression in human pulp cell cultures. J Endod 29 (2003) 201-204
27. D'Souza R., Brown L.R., Newland J.R., Levy B.M., and Lachman L.B. Detection and characterization of interleukin-1 in human dental pulps. Arch Oral Biol 34 (1989) 307-313
28. Lertchirakarn V., Birner R., and Messer H.H. Effects of interleukin-1 beta on human pulpal fibroblast proliferation and collagen synthesis. J Endod 24 (1998) 409-413
29. Wisithphrom K., and Windsor L.J. The effects of tumor necrosis factor-, interleukin-1, interleukin-6 and transforming growth factor-1 on pulp fibroblast mediated collagen degradation. J Endod 32 (2006) 853-861
30. Levin L.G., Rudd A., Bletsa A., and Reisner H. Expression of IL-8 by cells of the odontoblast layer in vitro. Eur J Oral Sci 107 (1999) 131-137
31. Camargo P.M., Lagos R., Pirih F.O., Benitez A., Nervina J.M., and Tetradis S. Prostaglandins E(2) and F(2alpha) enhance differentiation of cementoblastic cells. J Periodontol 76 (2005) 303-309
32. McCubrey J.A., May W.S., Duronio V., and Mufson A. Serine/threonine phosphorylation in cytokine signal transduction. Leukemia 14 (2000) 9-21
33. Tanaka K. Alteration of second messengers during acute cerebral ischemia: adenylate cyclase, cyclic AMP-dependent protein kinase, and cyclic AMP responsive element binding protein. Prog Neuobiol 65 (2001) 173-207
34. Kawase T., Orikasa M., and Suzuki A. Effect of bradykinin on intracellular signaling systems in a rat clonal dental pulp-cell line. Arch Oral Biol 38 (1993) 43-48
35. Kuan Y.H., Lin R.H., Tsao L.T., Lin C.N., and Wang J.P. Artocarpol A stimulation of superoxide anion generation in meutrophils involved the activation of PLC, PKC and p38 mitogen-activated PK signaling pathways. Br J Pharmacol 145 (2005) 460-468
36. Rao G.N., Madamanchi N.R., Lele M., et al. A potential role for extracellular signal-regulated kinases in prostaglandin F2alpha-induced protein synthesis in smooth muscle cells. J Biol Chen 274 (1999) 12925-12932
37. Spagnuolo G., D'Anto V., Valletta R., et al. Effect of 2-hydroxyethyl methacrylate on human pulp cell survival pathways ERK and AKT. J Endod 34 (2008) 684-688
38. Doolan C.M., Condliffe S.B., and Harvey B.J. Rapid non-genomic activation of cytosolic cyclic AMP-dependent protein kinase activity and [Ca(2+)](i) by 17beta-oestradiol in female rat distal colon. Br J Pharmacol 129 (2000) 1375-1386
39. DelloRusso C., Boullerne A.I., Gavrilyuk V., and Feinstein D.L. Inhibition of microglial inflammatory responses by norepinephrine: effects on nitric oxide and interleukin-1β production. J Neuroinflammation 1 (2004) 9