메뉴 건너뛰기




Volumn 33, Issue 11, 2014, Pages 1418-1428

BRCA1 regulates microtubule dynamics and taxane-induced apoptotic cell signaling

Author keywords

BRCA1; drug resistance; dynamics; microtubule; taxane

Indexed keywords

BRCA1 PROTEIN; CASPASE 8; CISPLATIN; ENHANCED GREEN FLUORESCENT PROTEIN; GAMMA TUBULIN; MESSENGER RNA; NOCODAZOLE; PACLITAXEL;

EID: 84896396518     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2013.85     Document Type: Article
Times cited : (48)

References (63)
  • 1
    • 1942438028 scopus 로고    scopus 로고
    • Microtubules as a target for anticancer drugs
    • Jordan MA, Wilson L. Microtubules as a target for anticancer drugs. Nat Rev Cancer 2004; 4: 253-265. (Pubitemid 38525281)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.4 , pp. 253-265
    • Jordan, M.A.1    Wilson, L.2
  • 2
    • 20544434991 scopus 로고    scopus 로고
    • Paclitaxel after doxorubicin plus cyclophosphamide as adjuvant chemotherapy for node-positive breast cancer: Results from NSABP B-28
    • Mamounas EP, Bryant J, Lembersky B, Fehrenbacher L, Sedlacek SM, Fisher B et al. Paclitaxel after doxorubicin plus cyclophosphamide as adjuvant chemotherapy for node-positive breast cancer: results from NSABP B-28. J Clin Oncol 2005; 23: 3686-3696.
    • (2005) J Clin Oncol , vol.23 , pp. 3686-3696
    • Mamounas, E.P.1    Bryant, J.2    Lembersky, B.3    Fehrenbacher, L.4    Sedlacek, S.M.5    Fisher, B.6
  • 8
    • 0034160108 scopus 로고    scopus 로고
    • A multicenter, randomized, phase III study of docetaxel plus best supportive care versus best supportive care in chemotherapy-naive patients with metastatic or non-resectable localized non-small cell lung cancer (NSCLC)
    • DOI 10.1016/S0169-5002(00)00094-5, PII S0169500200000945
    • Roszkowski K, Pluzanska A, Krzakowski M, Smith AP, Saigi E, Aasebo U et al. A multicenter, randomized, phase III study of docetaxel plus best supportive care versus best supportive care in chemotherapy-naive patients with metastatic or non-resectable localized non-small cell lung cancer (NSCLC). Lung Cancer 2000; 27: 145-157. (Pubitemid 30105654)
    • (2000) Lung Cancer , vol.27 , Issue.3 , pp. 145-157
    • Roszkowski, K.1    Pluzanska, A.2    Krzakowski, M.3    Smith, A.P.4    Saigi, E.5    Aasebo, U.6    Parisi, A.7    Pham Tran, N.8    Olivares, R.9    Berille, J.10
  • 10
    • 77957682309 scopus 로고    scopus 로고
    • Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: A randomised open-label trial
    • de Bono JS, Oudard S, Ozguroglu M, Hansen S, Machiels JP, Kocak I et al. Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial. Lancet 2010; 376: 1147-1154.
    • (2010) Lancet , vol.376 , pp. 1147-1154
    • De Bono, J.S.1    Oudard, S.2    Ozguroglu, M.3    Hansen, S.4    Machiels, J.P.5    Kocak, I.6
  • 13
    • 0033212570 scopus 로고    scopus 로고
    • Taxanes in combined-modality therapy for solid tumors
    • Choy H. Taxanes in combined-modality therapy for solid tumors. Oncology (Williston Park) 1999; 13(Suppl 5): 23-38.
    • (1999) Oncology (Williston Park) , vol.13 , Issue.SUPPL. 5 , pp. 23-38
    • Choy, H.1
  • 14
    • 37549025804 scopus 로고    scopus 로고
    • BRCA1 mRNA expression levels predict for overall survival in ovarian cancer after chemotherapy
    • Quinn JE, James CR, Stewart GE, Mulligan JM, White P, Chang GK et al. BRCA1 mRNA expression levels predict for overall survival in ovarian cancer after chemotherapy. Clin Cancer Res 2007; 13: 7413-7420.
    • (2007) Clin Cancer Res , vol.13 , pp. 7413-7420
    • Quinn, J.E.1    James, C.R.2    Stewart, G.E.3    Mulligan, J.M.4    White, P.5    Chang, G.K.6
  • 16
    • 78650376422 scopus 로고    scopus 로고
    • BRCA1 mRNA expression and outcome to neoadjuvant cisplatin-based chemotherapy in bladder cancer
    • Font A, Taron M, Gago JL, Costa C, Sanchez JJ, Carrato C et al. BRCA1 mRNA expression and outcome to neoadjuvant cisplatin-based chemotherapy in bladder cancer. Ann Oncol 2011; 22: 139-144.
    • (2011) Ann Oncol , vol.22 , pp. 139-144
    • Font, A.1    Taron, M.2    Gago, J.L.3    Costa, C.4    Sanchez, J.J.5    Carrato, C.6
  • 18
    • 84865762367 scopus 로고    scopus 로고
    • Human head and neck squamous cell carcinoma cell line with acquired cis-diamminedi-chloroplatinum-resistance shows remarkable upregulation of BRCA1 and hypersensitivity to taxane
    • Saiki Y, Ogawa T, Shiga K, Sunamura M, Kobayashi T, Horii AA. Human head and neck squamous cell carcinoma cell line with acquired cis-diamminedi- chloroplatinum-resistance shows remarkable upregulation of BRCA1 and hypersensitivity to taxane. Int J Otolaryngol 2011; 2011: 521852.
    • (2011) Int J Otolaryngol , vol.2011 , pp. 521852
    • Saiki, Y.1    Ogawa, T.2    Shiga, K.3    Sunamura, M.4    Kobayashi, T.5    Horii, A.A.6
  • 19
    • 4544374528 scopus 로고    scopus 로고
    • BRCA1 and BRCA2: 1994 and beyond
    • DOI 10.1038/nrc1431
    • Narod SA, Foulkes WD. BRCA1 and BRCA2: 1994 and beyond. Nat Rev Cancer 2004; 4: 665-676. (Pubitemid 39215065)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.9 , pp. 665-676
    • Narod, S.A.1    Foulkes, W.D.2
  • 20
    • 27644543144 scopus 로고    scopus 로고
    • The role of the BRCA1 tumor suppressor in DNA double-strand break repair
    • DOI 10.1158/1541-7786.MCR-05-0192
    • Zhang J, Powell SN. The role of the BRCA1 tumor suppressor in DNA double-strand break repair. Mol Cancer Res 2005; 3: 531-539. (Pubitemid 41567272)
    • (2005) Molecular Cancer Research , vol.3 , Issue.10 , pp. 531-539
    • Zhang, J.1    Powell, S.N.2
  • 22
    • 79551692138 scopus 로고    scopus 로고
    • A novel role for BRCA1 in regulating breast cancer cell spreading and motility
    • Coene ED, Gadelha C, White N, Malhas A, Thomas B, Shaw M et al. A novel role for BRCA1 in regulating breast cancer cell spreading and motility. J Cell Biol 2011; 192: 497-512.
    • (2011) J Cell Biol , vol.192 , pp. 497-512
    • Coene, E.D.1    Gadelha, C.2    White, N.3    Malhas, A.4    Thomas, B.5    Shaw, M.6
  • 23
    • 69249157465 scopus 로고    scopus 로고
    • The BRCA1-dependent ubiquitin ligase, gamma-tubulin, and centro-somes
    • Parvin JD. The BRCA1-dependent ubiquitin ligase, gamma-tubulin, and centro-somes. Environ Mol Mutagen 2009; 50: 649-653.
    • (2009) Environ Mol Mutagen , vol.50 , pp. 649-653
    • Parvin, J.D.1
  • 25
    • 25444455576 scopus 로고    scopus 로고
    • Centrosomal microtubule nucleation activity is inhibited by BRCA1-dependent ubiquitination
    • DOI 10.1128/MCB.25.19.8656-8668.2005
    • Sankaran S, Starita LM, Groen AC, Ko MJ, Parvin JD. Centrosomal microtubule nucleation activity is inhibited by BRCA1-dependent ubiquitination. Mol Cell Biol 2005; 25: 8656-8668. (Pubitemid 41369184)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.19 , pp. 8656-8668
    • Sankaran, S.1    Starita, L.M.2    Groen, A.C.3    Ko, M.J.4    Parvin, J.D.5
  • 27
    • 48449098623 scopus 로고    scopus 로고
    • Cancer cells display profound intra-and interline variation following prolonged exposure to antimitotic drugs
    • Gascoigne KE, Taylor SS. Cancer cells display profound intra-and interline variation following prolonged exposure to antimitotic drugs. Cancer Cell 2008; 14: 111-122.
    • (2008) Cancer Cell , vol.14 , pp. 111-122
    • Gascoigne, K.E.1    Taylor, S.S.2
  • 28
    • 70349974226 scopus 로고    scopus 로고
    • Paclitaxel promotes a caspase 8-mediated apoptosis through death effector domain association with microtubules
    • Mielgo A, Torres VA, Clair K, Barbero S, Stupack DG. Paclitaxel promotes a caspase 8-mediated apoptosis through death effector domain association with microtubules. Oncogene 2009; 28: 3551-3562.
    • (2009) Oncogene , vol.28 , pp. 3551-3562
    • Mielgo, A.1    Torres, V.A.2    Clair, K.3    Barbero, S.4    Stupack, D.G.5
  • 29
    • 0029360519 scopus 로고
    • Microtubule dynamics: Taking aim at a moving target
    • Wilson L, Jordan MA. Microtubule dynamics: taking aim at a moving target. Chem Biol 1995; 2: 569-573.
    • (1995) Chem Biol , vol.2 , pp. 569-573
    • Wilson, L.1    Jordan, M.A.2
  • 30
    • 27544464474 scopus 로고    scopus 로고
    • TIP maker and TIP marker; EB1 as a master controller of microtubule plus ends
    • DOI 10.1083/jcb.200509150
    • Vaughan KT. TIP maker and TIP marker; EB1 as a master controller of microtubule plus ends. J Cell Biol 2005; 171: 197-200. (Pubitemid 41540012)
    • (2005) Journal of Cell Biology , vol.171 , Issue.2 , pp. 197-200
    • Vaughan, K.T.1
  • 32
    • 0037223823 scopus 로고    scopus 로고
    • Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL
    • DOI 10.1038/ncb899
    • Hergovich A, Lisztwan J, Barry R, Ballschmieter P, Krek W. Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL. Nat Cell Biol 2003; 5: 64-70. (Pubitemid 36054331)
    • (2003) Nature Cell Biology , vol.5 , Issue.1 , pp. 64-70
    • Hergovich, A.1    Lisztwan, J.2    Barry, R.3    Ballschmieter, P.4    Krek, W.5
  • 33
    • 79953706562 scopus 로고    scopus 로고
    • Predictive impact of DNA repair functionality on clinical outcome of advanced sarcoma patients treated with trabectedin: A retrospective multicentric study
    • Schoffski P, Taron M, Jimeno J, Grosso F, Sanfilipio R, Casali PG et al. Predictive impact of DNA repair functionality on clinical outcome of advanced sarcoma patients treated with trabectedin: a retrospective multicentric study. Eur J Cancer 2011; 47: 1006-1012.
    • (2011) Eur J Cancer , vol.47 , pp. 1006-1012
    • Schoffski, P.1    Taron, M.2    Jimeno, J.3    Grosso, F.4    Sanfilipio, R.5    Casali, P.G.6
  • 35
    • 37849039228 scopus 로고    scopus 로고
    • Hereditary breast cancer: Part I. Diagnosing hereditary breast cancer syndromes
    • Lynch HT, Silva E, Snyder C, Lynch JF. Hereditary breast cancer: part I. Diagnosing hereditary breast cancer syndromes. Breast J 2008; 14: 3-13.
    • (2008) Breast J , vol.14 , pp. 3-13
    • Lynch, H.T.1    Silva, E.2    Snyder, C.3    Lynch, J.F.4
  • 36
    • 77955886707 scopus 로고    scopus 로고
    • Somatic mutations in BRCA1 and BRCA2 could expand the number of patients that benefit from poly (ADP ribose) polymerase inhibitors in ovarian cancer
    • Hennessy BT, Timms KM, Carey MS, Gutin A, Meyer LA, Flake 2nd DD et al. Somatic mutations in BRCA1 and BRCA2 could expand the number of patients that benefit from poly (ADP ribose) polymerase inhibitors in ovarian cancer. J Clin Oncol 2010; 28: 3570-3576.
    • (2010) J Clin Oncol , vol.28 , pp. 3570-3576
    • Hennessy, B.T.1    Timms, K.M.2    Carey, M.S.3    Gutin, A.4    Meyer, L.A.5    Flake II, D.D.6
  • 37
    • 84860456671 scopus 로고    scopus 로고
    • BRCA1 and BRCA2 mutations correlate with TP53 abnormalities and presence of immune cell infiltrates in ovarian high-grade serous carcinoma
    • McAlpine JN, Porter H, Kobel M, Nelson BH, Prentice LM, Kalloger SE et al. BRCA1 and BRCA2 mutations correlate with TP53 abnormalities and presence of immune cell infiltrates in ovarian high-grade serous carcinoma. Mod Pathol 2012; 25: 740-750.
    • (2012) Mod Pathol , vol.25 , pp. 740-750
    • McAlpine, J.N.1    Porter, H.2    Kobel, M.3    Nelson, B.H.4    Prentice, L.M.5    Kalloger, S.E.6
  • 38
    • 77958606449 scopus 로고    scopus 로고
    • Sporadic breast carcinomas with somatic BRCA1 gene deletions share genotype/phenotype features with familial breast carcinomas
    • Rhiem K, Todt U, Wappenschmidt B, Klein A, Wardelmann E, Schmutzler RK. Sporadic breast carcinomas with somatic BRCA1 gene deletions share genotype/phenotype features with familial breast carcinomas. Anticancer Res 2010; 30: 3445-3449.
    • (2010) Anticancer Res , vol.30 , pp. 3445-3449
    • Rhiem, K.1    Todt, U.2    Wappenschmidt, B.3    Klein, A.4    Wardelmann, E.5    Schmutzler, R.K.6
  • 39
    • 80054915400 scopus 로고    scopus 로고
    • MRNA expression of BRCA1, PIAS1, and PIAS4 and survival after second-line docetaxel in advanced gastric cancer
    • Wei J, Costa C, Ding Y, Zou Z, Yu L, Sanchez JJ et al. mRNA expression of BRCA1, PIAS1, and PIAS4 and survival after second-line docetaxel in advanced gastric cancer. J Natl Cancer Inst 2011; 103: 1552-1556.
    • (2011) J Natl Cancer Inst , vol.103 , pp. 1552-1556
    • Wei, J.1    Costa, C.2    Ding, Y.3    Zou, Z.4    Yu, L.5    Sanchez, J.J.6
  • 40
    • 67649431893 scopus 로고    scopus 로고
    • Customized treatment in non-small-cell lung cancer based on EGFR mutations and BRCA1 mRNA expression
    • Rosell R, Perez-Roca L, Sanchez JJ, Cobo M, Moran T, Chaib I et al. Customized treatment in non-small-cell lung cancer based on EGFR mutations and BRCA1 mRNA expression. PLoS One 2009; 4e5133.
    • (2009) PLoS One
    • Rosell, R.1    Perez-Roca, L.2    Sanchez, J.J.3    Cobo, M.4    Moran, T.5    Chaib, I.6
  • 41
    • 0021717132 scopus 로고
    • MAP 4: Occurrence in mouse tissues
    • DOI 10.1083/jcb.99.4.1309
    • Parysek LM, Asnes CF, Olmsted JB. MAP 4: occurrence in mouse tissues. J Cell Biol 1984; 99(Pt 1): 1309-1315. (Pubitemid 15201616)
    • (1984) Journal of Cell Biology , vol.99 , Issue.4 , pp. 1309-1315
    • Parysek, L.M.1    Asnes, C.F.2    Olmsted, J.B.3
  • 42
    • 0030783012 scopus 로고    scopus 로고
    • 2S complex with two tubulin molecules
    • DOI 10.1021/bi971491b
    • Jourdain L, Curmi P, Sobel A, Pantaloni D, Carlier MF. Stathmin: a tubulin-sequestering protein which forms a ternary T2S complex with two tubulin molecules. Biochemistry 1997; 36: 10817-10821. (Pubitemid 27396235)
    • (1997) Biochemistry , vol.36 , Issue.36 , pp. 10817-10821
    • Jourdain, L.1    Curmi, P.2    Sobel, A.3    Pantaloni, D.4    Carlier, M.-F.5
  • 43
    • 0036678880 scopus 로고    scopus 로고
    • Enhanced microtubule-dependent trafficking and p53 nuclear accumulation by suppression of microtubule dynamics
    • Giannakakou P, Nakano M, Nicolaou KC, O'Brate A, Yu J, Blagosklonny MV et al. Enhanced microtubule-dependent trafficking and p53 nuclear accumulation by suppression of microtubule dynamics. Proc Natl Acad Sci USA 2002; 99: 10855-10860.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 10855-10860
    • Giannakakou, P.1    Nakano, M.2    Nicolaou, K.C.3    O'Brate, A.4    Yu, J.5    Blagosklonny, M.V.6
  • 45
    • 80052808323 scopus 로고    scopus 로고
    • Taxane-induced blockade to nuclear accumulation of the androgen receptor predicts clinical responses in metastatic prostate cancer
    • Darshan MS, Loftus MS, Thadani-Mulero M, Levy BP, Escuin D, Zhou XK et al. Taxane-induced blockade to nuclear accumulation of the androgen receptor predicts clinical responses in metastatic prostate cancer. Cancer Res 2011; 71: 6019-6029.
    • (2011) Cancer Res , vol.71 , pp. 6019-6029
    • Darshan, M.S.1    Loftus, M.S.2    Thadani-Mulero, M.3    Levy, B.P.4    Escuin, D.5    Zhou, X.K.6
  • 46
    • 84859495330 scopus 로고    scopus 로고
    • Microtubules regulate hypoxia-inducible factor-1alpha protein trafficking and activity: Implications for taxane therapy
    • Carbonaro M, Escuin D, O'Brate A, Thadani-Mulero M, Giannakakou P. Microtubules regulate hypoxia-inducible factor-1alpha protein trafficking and activity: implications for taxane therapy. J Biol Chem 2012; 287: 11859-11869.
    • (2012) J Biol Chem , vol.287 , pp. 11859-11869
    • Carbonaro, M.1    Escuin, D.2    O'Brate, A.3    Thadani-Mulero, M.4    Giannakakou, P.5
  • 47
    • 77957198722 scopus 로고    scopus 로고
    • Quantitative image analysis identifies pVHL as a key regulator of microtubule dynamic instability
    • Thoma CR, Matov A, Gutbrodt KL, Hoerner CR, Smole Z, Krek W et al. Quantitative image analysis identifies pVHL as a key regulator of microtubule dynamic instability. J Cell Biol 2010; 190: 991-1003.
    • (2010) J Cell Biol , vol.190 , pp. 991-1003
    • Thoma, C.R.1    Matov, A.2    Gutbrodt, K.L.3    Hoerner, C.R.4    Smole, Z.5    Krek, W.6
  • 48
    • 0035176077 scopus 로고    scopus 로고
    • Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3β phosphorylation
    • DOI 10.1016/S0960-9822(01)00002-1
    • Zumbrunn J, Kinoshita K, Hyman AA, Nathke IS. Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation. Curr Biol 2001; 11: 44-49. (Pubitemid 32062715)
    • (2001) Current Biology , vol.11 , Issue.1 , pp. 44-49
    • Zumbrunn, J.1    Kinoshita, K.2    Hyman, A.A.3    Nathke, I.S.4
  • 50
    • 69249155079 scopus 로고    scopus 로고
    • BRCA1 interaction of centrosomal protein Nlp is required for successful mitotic progression
    • Jin S, Gao H, Mazzacurati L, Wang Y, Fan W, Chen Q et al. BRCA1 interaction of centrosomal protein Nlp is required for successful mitotic progression. J Biol Chem 2009; 284: 22970-22977.
    • (2009) J Biol Chem , vol.284 , pp. 22970-22977
    • Jin, S.1    Gao, H.2    Mazzacurati, L.3    Wang, Y.4    Fan, W.5    Chen, Q.6
  • 52
    • 0035502955 scopus 로고    scopus 로고
    • Identification of a gamma-tubulin-binding domain in BRCA1
    • Hsu LC, Doan TP, White RL. Identification of a gamma-tubulin-binding domain in BRCA1. Cancer Res 2001; 61: 7713-7718.
    • (2001) Cancer Res , vol.61 , pp. 7713-7718
    • Hsu, L.C.1    Doan, T.P.2    White, R.L.3
  • 53
    • 84863904678 scopus 로고    scopus 로고
    • Axon injury and stress trigger a microtubule-based neuroprotective pathway
    • Chen L, Stone MC, Tao J, Rolls MM. Axon injury and stress trigger a microtubule-based neuroprotective pathway. Proc Natl Acad Sci USA 2012; 109: 11842-11847.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 11842-11847
    • Chen, L.1    Stone, M.C.2    Tao, J.3    Rolls, M.M.4
  • 55
    • 78651225388 scopus 로고    scopus 로고
    • Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling
    • Xu G, Paige JS, Jaffrey SR. Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling. Nat Biotechnol 2010; 28: 868-873.
    • (2010) Nat Biotechnol , vol.28 , pp. 868-873
    • Xu, G.1    Paige, J.S.2    Jaffrey, S.R.3
  • 57
    • 0025872827 scopus 로고
    • Resistance to antimitotic drugs in Chinese hamster ovary cells correlates with changes in the level of polymerized tubulin
    • Minotti AM, Barlow SB, Cabral F. Resistance to antimitotic drugs in Chinese hamster ovary cells correlates with changes in the level of polymerized tubulin. J Biol Chem 1991; 266: 3987-3994. (Pubitemid 21909306)
    • (1991) Journal of Biological Chemistry , vol.266 , Issue.6 , pp. 3987-3994
    • Minotti, A.M.1    Barlow, S.B.2    Cabral, F.3
  • 59
    • 65649130809 scopus 로고    scopus 로고
    • The protein farnesyltransferase regulates HDAC6 activity in a microtubule-dependent manner
    • Zhou J, Vos CC, Gjyrezi A, Yoshida M, Khuri FR, Tamanoi F et al. The protein farnesyltransferase regulates HDAC6 activity in a microtubule-dependent manner. J Biol Chem 2009; 284: 9648-9655.
    • (2009) J Biol Chem , vol.284 , pp. 9648-9655
    • Zhou, J.1    Vos, C.C.2    Gjyrezi, A.3    Yoshida, M.4    Khuri, F.R.5    Tamanoi, F.6
  • 60
    • 80051932974 scopus 로고    scopus 로고
    • Farnesyl transferase expression determines clinical response to the docetaxel-lonafarnib combination in patients with advanced malignancies
    • Kauh J, Chanel-Vos C, Escuin D, Fanucchi MP, Harvey RD, Saba N et al. Farnesyl transferase expression determines clinical response to the docetaxel-lonafarnib combination in patients with advanced malignancies. Cancer 2011; 117: 4049-4059.
    • (2011) Cancer , vol.117 , pp. 4049-4059
    • Kauh, J.1    Chanel-Vos, C.2    Escuin, D.3    Fanucchi, M.P.4    Harvey, R.D.5    Saba, N.6
  • 61
    • 75749155892 scopus 로고    scopus 로고
    • From signaling pathways to microtubule dynamics: The key players
    • Etienne-Manneville S. From signaling pathways to microtubule dynamics: the key players. Curr Opin Cell Biol 2010; 22: 104-111.
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 104-111
    • Etienne-Manneville, S.1
  • 62
    • 78651338243 scopus 로고    scopus 로고
    • Microtubule disruption targets HIF-1alpha mRNA to cytoplasmic P-bodies for translational repression
    • Carbonaro M, O'Brate A, Giannakakou P. Microtubule disruption targets HIF-1alpha mRNA to cytoplasmic P-bodies for translational repression. J Cell Biol 2011; 192: 83-99.
    • (2011) J Cell Biol , vol.192 , pp. 83-99
    • Carbonaro, M.1    O'Brate, A.2    Giannakakou, P.3
  • 63
    • 20944437248 scopus 로고    scopus 로고
    • The synergistic combination of the farnesyl transferase inhibitor lonafarnib and paclitaxel enhances tubulin acetylation and requires a functional tubulin deacetylase
    • DOI 10.1158/0008-5472.CAN-04-3757
    • Marcus AI, Zhou J, O'Brate A, Hamel E, Wong J, Nivens M et al. The synergistic combination of the farnesyl transferase inhibitor lonafarnib and paclitaxel enhances tubulin acetylation and requires a functional tubulin deacetylase. Cancer Res 2005; 65: 3883-3893. (Pubitemid 40616370)
    • (2005) Cancer Research , vol.65 , Issue.9 , pp. 3883-3893
    • Marcus, A.I.1    Zhou, J.2    O'Brate, A.3    Hamel, E.4    Wong, J.5    Nivens, M.6    El-Naggar, A.7    Yao, T.-P.8    Khuri, F.R.9    Giannakakou, P.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.