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Volumn 4, Issue 5, 2009, Pages

Customized Treatment in Non-Small-Cell Lung Cancer Based on EGFR Mutations and BRCA1 mRNA Expression

(24)  Rosell, Rafael a,b   Perez Roca, Laia a   Sanchez, Jose Javier c   Cobo, Manuel d   Moran, Teresa a   Chaib, Imane a   Provencio, Mariano e   Domine, Manuel f   Sala, Maria Angeles g   Jimenez, Ulpiano h   Diz, Pilar i   Barneto, Isidoro j   Macias, Jose Antonio k   de las Peñas, Ramon l   Catot, Silvia m   Isla, Dolores n   Sanchez, Jose Miguel o,u   Ibeas, Rafael p   Lopez Vivanco, Guillermo q   Oramas, Juana r   more..


Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; CARRIER PROTEIN; CISPLATIN; DEOXYCYTIDINE; DOCETAXEL; DRUG DERIVATIVE; EPIDERMAL GROWTH FACTOR RECEPTOR; FAM175A PROTEIN, HUMAN; GEMCITABINE; MESSENGER RNA; NUCLEAR PROTEIN; RAP80 PROTEIN, HUMAN; RNA; TAXOID;

EID: 67649431893     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0005133     Document Type: Article
Times cited : (144)

References (36)
  • 1
    • 0042413836 scopus 로고    scopus 로고
    • Randomized, multinational, phase III study of docetaxel plus platinum combinations versus vinorelbine plus cisplatin for advanced non-small-cell lung cancer: the TAX 326 study group
    • Fossella F, Pereira JR, von Pawel J, Pluzanska A, Gorbounova V, et al.(2003) Randomized, multinational, phase III study of docetaxel plus platinum combinations versus vinorelbine plus cisplatin for advanced non-small-cell lung cancer: the TAX 326 study group. J Clin Oncol 21: 3016-3024.
    • (2003) J Clin Oncol , vol.21 , pp. 3016-3024
    • Fossella, F.1    Pereira, J.R.2    von Pawel, J.3    Pluzanska, A.4    Gorbounova, V.5
  • 2
    • 49049089802 scopus 로고    scopus 로고
    • Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer
    • Scagliotti GV, Parikh P, von Pawel J, Biesma B, Vansteenkiste J, et al.(2008) Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer. J Clin Oncol 26: 3543-3551.
    • (2008) J Clin Oncol , vol.26 , pp. 3543-3551
    • Scagliotti, G.V.1    Parikh, P.2    von Pawel, J.3    Biesma, B.4    Vansteenkiste, J.5
  • 3
    • 34447573875 scopus 로고    scopus 로고
    • Customizing cisplatin based on quantitative excision repair cross-complementing 1 mRNA expression: a phase III trial in non-small-cell lung cancer
    • Cobo M, Isla D, Massuti B, Montes A, Sanchez JM, et al.(2007) Customizing cisplatin based on quantitative excision repair cross-complementing 1 mRNA expression: a phase III trial in non-small-cell lung cancer. J Clin Oncol 25: 2747-2754.
    • (2007) J Clin Oncol , vol.25 , pp. 2747-2754
    • Cobo, M.1    Isla, D.2    Massuti, B.3    Montes, A.4    Sanchez, J.M.5
  • 4
    • 52949123622 scopus 로고    scopus 로고
    • Comparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRAS
    • Guha U, Chaerkady R, Marimuthu A, Patterson AS, Kashyap MK, et al.(2008) Comparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRAS. Proc Natl Acad Sci U S A 105: 14112-14117.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 14112-14117
    • Guha, U.1    Chaerkady, R.2    Marimuthu, A.3    Patterson, A.S.4    Kashyap, M.K.5
  • 5
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, et al.(2004) Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 350: 2129-2139.
    • (2004) N Engl J Med , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3    Gurubhagavatula, S.4    Okimoto, R.A.5
  • 6
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy
    • Paez JG, Janne PA, Lee JC, Tracy S, Greulich H, et al.(2004) EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 304: 1497-1500.
    • (2004) Science , vol.304 , pp. 1497-1500
    • Paez, J.G.1    Janne, P.A.2    Lee, J.C.3    Tracy, S.4    Greulich, H.5
  • 7
    • 4444344330 scopus 로고    scopus 로고
    • EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
    • Pao W, Miller V, Zakowski M, Doherty J, Politi K, et al.(2004) EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci U S A 101: 13306-13311.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 13306-13311
    • Pao, W.1    Miller, V.2    Zakowski, M.3    Doherty, J.4    Politi, K.5
  • 8
    • 45149084723 scopus 로고    scopus 로고
    • First-line gefitinib in patients with advanced non-small-cell lung cancer harboring somatic EGFR mutations
    • Sequist LV, Martins RG, Spigel D, Grunberg SM, Spira A, et al.(2008) First-line gefitinib in patients with advanced non-small-cell lung cancer harboring somatic EGFR mutations. J Clin Oncol 26: 2442-2449.
    • (2008) J Clin Oncol , vol.26 , pp. 2442-2449
    • Sequist, L.V.1    Martins, R.G.2    Spigel, D.3    Grunberg, S.M.4    Spira, A.5
  • 9
    • 23844490782 scopus 로고    scopus 로고
    • Activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor are associated with improved survival in gefitinib-treated chemorefractory lung adenocarcinomas
    • Taron M, Ichinose Y, Rosell R, Mok T, Massuti B, et al.(2005) Activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor are associated with improved survival in gefitinib-treated chemorefractory lung adenocarcinomas. Clin Cancer Res 11: 5878-5885.
    • (2005) Clin Cancer Res , vol.11 , pp. 5878-5885
    • Taron, M.1    Ichinose, Y.2    Rosell, R.3    Mok, T.4    Massuti, B.5
  • 10
    • 34548484397 scopus 로고    scopus 로고
    • Pooled analysis of the prospective trials of gefitinib monotherapy for EGFR-mutant non-small cell lung cancers
    • Costa DB, Kobayashi S, Tenen DG, Huberman MS, (2007) Pooled analysis of the prospective trials of gefitinib monotherapy for EGFR-mutant non-small cell lung cancers. Lung Cancer 58: 95-103.
    • (2007) Lung Cancer , vol.58 , pp. 95-103
    • Costa, D.B.1    Kobayashi, S.2    Tenen, D.G.3    Huberman, M.S.4
  • 11
    • 20044364933 scopus 로고    scopus 로고
    • EGFR mutations in non-small-cell lung cancer: analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment
    • Marchetti A, Martella C, Felicioni L, Barassi F, Salvatore S, et al.(2005) EGFR mutations in non-small-cell lung cancer: analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment. J Clin Oncol 23: 857-865.
    • (2005) J Clin Oncol , vol.23 , pp. 857-865
    • Marchetti, A.1    Martella, C.2    Felicioni, L.3    Barassi, F.4    Salvatore, S.5
  • 12
    • 0035807219 scopus 로고    scopus 로고
    • Inhibition of BRCA1 leads to increased chemoresistance to microtubule-interfering agents, an effect that involves the JNK pathway
    • Lafarge S, Sylvain V, Ferrara M, Bignon YJ, (2001) Inhibition of BRCA1 leads to increased chemoresistance to microtubule-interfering agents, an effect that involves the JNK pathway. Oncogene 20: 6597-6606.
    • (2001) Oncogene , vol.20 , pp. 6597-6606
    • Lafarge, S.1    Sylvain, V.2    Ferrara, M.3    Bignon, Y.J.4
  • 13
    • 0032521537 scopus 로고    scopus 로고
    • BRCA1 up-regulation is associated with repair-mediated resistance to cis-diamminedichloroplatinum(II)
    • Husain A, He G, Venkatraman ES, Spriggs DR, (1998) BRCA1 up-regulation is associated with repair-mediated resistance to cis-diamminedichloroplatinum(II). Cancer Res 58: 1120-1123.
    • (1998) Cancer Res , vol.58 , pp. 1120-1123
    • Husain, A.1    He, G.2    Venkatraman, E.S.3    Spriggs, D.R.4
  • 14
    • 0034604716 scopus 로고    scopus 로고
    • The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatin
    • Bhattacharyya A, Ear US, Koller BH, Weichselbaum RR, Bishop DK, (2000) The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatin. J Biol Chem 275: 23899-23903.
    • (2000) J Biol Chem , vol.275 , pp. 23899-23903
    • Bhattacharyya, A.1    Ear, U.S.2    Koller, B.H.3    Weichselbaum, R.R.4    Bishop, D.K.5
  • 15
    • 0033603440 scopus 로고    scopus 로고
    • BRCA1 expression restores radiation resistance in BRCA1-defective cancer cells through enhancement of transcription-coupled DNA repair
    • Abbott DW, Thompson ME, Robinson-Benion C, Tomlinson G, Jensen RA, et al.(1999) BRCA1 expression restores radiation resistance in BRCA1-defective cancer cells through enhancement of transcription-coupled DNA repair. J Biol Chem 274: 18808-18812.
    • (1999) J Biol Chem , vol.274 , pp. 18808-18812
    • Abbott, D.W.1    Thompson, M.E.2    Robinson-Benion, C.3    Tomlinson, G.4    Jensen, R.A.5
  • 16
    • 0035959804 scopus 로고    scopus 로고
    • BRCA1 and GADD45 mediated G2/M cell cycle arrest in response to antimicrotubule agents
    • Mullan PB, Quinn JE, Gilmore PM, McWilliams S, Andrews H, et al.(2001) BRCA1 and GADD45 mediated G2/M cell cycle arrest in response to antimicrotubule agents. Oncogene 20: 6123-6131.
    • (2001) Oncogene , vol.20 , pp. 6123-6131
    • Mullan, P.B.1    Quinn, J.E.2    Gilmore, P.M.3    McWilliams, S.4    Andrews, H.5
  • 17
    • 0141954010 scopus 로고    scopus 로고
    • BRCA1 functions as a differential modulator of chemotherapy-induced apoptosis
    • Quinn JE, Kennedy RD, Mullan PB, Gilmore PM, Carty M, et al.(2003) BRCA1 functions as a differential modulator of chemotherapy-induced apoptosis. Cancer Res 63: 6221-6228.
    • (2003) Cancer Res , vol.63 , pp. 6221-6228
    • Quinn, J.E.1    Kennedy, R.D.2    Mullan, P.B.3    Gilmore, P.M.4    Carty, M.5
  • 18
    • 33646409883 scopus 로고    scopus 로고
    • BRCA1 downregulation leads to premature inactivation of spindle checkpoint and confers paclitaxel resistance
    • Chabalier C, Lamare C, Racca C, Privat M, Valette A, et al.(2006) BRCA1 downregulation leads to premature inactivation of spindle checkpoint and confers paclitaxel resistance. Cell Cycle 5: 1001-1007.
    • (2006) Cell Cycle , vol.5 , pp. 1001-1007
    • Chabalier, C.1    Lamare, C.2    Racca, C.3    Privat, M.4    Valette, A.5
  • 19
    • 37549025804 scopus 로고    scopus 로고
    • BRCA1 mRNA Expression Levels Predict for Overall Survival in Ovarian Cancer after Chemotherapy
    • Quinn JE, James CR, Stewart GE, Mulligan JM, White P, et al.(2007) BRCA1 mRNA Expression Levels Predict for Overall Survival in Ovarian Cancer after Chemotherapy. Clin Cancer Res 13: 7413-7420.
    • (2007) Clin Cancer Res , vol.13 , pp. 7413-7420
    • Quinn, J.E.1    James, C.R.2    Stewart, G.E.3    Mulligan, J.M.4    White, P.5
  • 20
    • 44349090911 scopus 로고    scopus 로고
    • ERCC1 and BRCA1 mRNA expression levels in metastatic malignant effusions is associated with chemosensitivity to cisplatin and/or docetaxel
    • Wang L, Wei J, Qian X, Yin H, Zhao Y, et al.(2008) ERCC1 and BRCA1 mRNA expression levels in metastatic malignant effusions is associated with chemosensitivity to cisplatin and/or docetaxel. BMC Cancer 8: 97.
    • (2008) BMC Cancer , vol.8 , pp. 97
    • Wang, L.1    Wei, J.2    Qian, X.3    Yin, H.4    Zhao, Y.5
  • 21
    • 19544379515 scopus 로고    scopus 로고
    • BRCA1 mRNA expression levels as an indicator of chemoresistance in lung cancer
    • Taron M, Rosell R, Felip E, Mendez P, Souglakos J, et al.(2004) BRCA1 mRNA expression levels as an indicator of chemoresistance in lung cancer. Hum Mol Genet 13: 2443-2449.
    • (2004) Hum Mol Genet , vol.13 , pp. 2443-2449
    • Taron, M.1    Rosell, R.2    Felip, E.3    Mendez, P.4    Souglakos, J.5
  • 22
    • 36749022214 scopus 로고    scopus 로고
    • The DNA damage response: ten years after
    • Harper JW, Elledge SJ, (2007) The DNA damage response: ten years after. Mol Cell 28: 739-745.
    • (2007) Mol Cell , vol.28 , pp. 739-745
    • Harper, J.W.1    Elledge, S.J.2
  • 23
    • 34249946686 scopus 로고    scopus 로고
    • Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response
    • Wang B, Matsuoka S, Ballif BA, Zhang D, Smogorzewska A, et al.(2007) Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response. Science 316: 1194-1198.
    • (2007) Science , vol.316 , pp. 1194-1198
    • Wang, B.1    Matsuoka, S.2    Ballif, B.A.3    Zhang, D.4    Smogorzewska, A.5
  • 24
    • 34249949779 scopus 로고    scopus 로고
    • RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites
    • Sobhian B, Shao G, Lilli DR, Culhane AC, Moreau LA, et al.(2007) RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites. Science 316: 1198-1202.
    • (2007) Science , vol.316 , pp. 1198-1202
    • Sobhian, B.1    Shao, G.2    Lilli, D.R.3    Culhane, A.C.4    Moreau, L.A.5
  • 25
    • 34249950879 scopus 로고    scopus 로고
    • Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response
    • Kim H, Chen J, Yu X, (2007) Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response. Science 316: 1202-1205.
    • (2007) Science , vol.316 , pp. 1202-1205
    • Kim, H.1    Chen, J.2    Yu, X.3
  • 26
    • 33744814638 scopus 로고    scopus 로고
    • Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors
    • Politi K, Zakowski MF, Fan PD, Schonfeld EA, Pao W, et al.(2006) Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors. Genes Dev 20: 1496-1510.
    • (2006) Genes Dev , vol.20 , pp. 1496-1510
    • Politi, K.1    Zakowski, M.F.2    Fan, P.D.3    Schonfeld, E.A.4    Pao, W.5
  • 27
    • 36749025467 scopus 로고    scopus 로고
    • Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage
    • Wang B, Elledge SJ, (2007) Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage. Proc Natl Acad Sci U S A 104: 20759-20763.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 20759-20763
    • Wang, B.1    Elledge, S.J.2
  • 28
    • 34547120473 scopus 로고    scopus 로고
    • The ubiquitin-interacting motif containing protein RAP80 interacts with BRCA1 and functions in DNA damage repair response
    • Yan J, Kim YS, Yang XP, Li LP, Liao G, et al.(2007) The ubiquitin-interacting motif containing protein RAP80 interacts with BRCA1 and functions in DNA damage repair response. Cancer Res 67: 6647-6656.
    • (2007) Cancer Res , vol.67 , pp. 6647-6656
    • Yan, J.1    Kim, Y.S.2    Yang, X.P.3    Li, L.P.4    Liao, G.5
  • 29
    • 0037050352 scopus 로고    scopus 로고
    • Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer
    • Schiller JH, Harrington D, Belani CP, Langer C, Sandler A, et al.(2002) Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. N Engl J Med 346: 92-98.
    • (2002) N Engl J Med , vol.346 , pp. 92-98
    • Schiller, J.H.1    Harrington, D.2    Belani, C.P.3    Langer, C.4    Sandler, A.5
  • 30
    • 34548550432 scopus 로고    scopus 로고
    • Identification of an integrated SV40 T/t-antigen cancer signature in aggressive human breast, prostate, and lung carcinomas with poor prognosis
    • Deeb KK, Michalowska AM, Yoon CY, Krummey SM, Hoenerhoff MJ, et al.(2007) Identification of an integrated SV40 T/t-antigen cancer signature in aggressive human breast, prostate, and lung carcinomas with poor prognosis. Cancer Res 67: 8065-8080.
    • (2007) Cancer Res , vol.67 , pp. 8065-8080
    • Deeb, K.K.1    Michalowska, A.M.2    Yoon, C.Y.3    Krummey, S.M.4    Hoenerhoff, M.J.5
  • 31
    • 42549088992 scopus 로고    scopus 로고
    • BRCA1: A Novel Prognostic Factor in Resected Non-Small-Cell Lung Cancer
    • Rosell R, Skrzypski M, Jassem E, Taron M, Bartolucci R, et al.(2007) BRCA1: A Novel Prognostic Factor in Resected Non-Small-Cell Lung Cancer. PLoS ONE 2: e1129.
    • (2007) PLoS ONE , vol.2
    • Rosell, R.1    Skrzypski, M.2    Jassem, E.3    Taron, M.4    Bartolucci, R.5
  • 32
    • 44449136965 scopus 로고    scopus 로고
    • HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response
    • Ayoub N, Jeyasekharan AD, Bernal JA, Venkitaraman AR, (2008) HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response. Nature 453: 682-686.
    • (2008) Nature , vol.453 , pp. 682-686
    • Ayoub, N.1    Jeyasekharan, A.D.2    Bernal, J.A.3    Venkitaraman, A.R.4
  • 33
    • 4444298254 scopus 로고    scopus 로고
    • Casein kinase II alpha subunit and C1-inhibitor are independent predictors of outcome in patients with squamous cell carcinoma of the lung
    • P O.c
    • P Oc, Rusch V, Talbot SG, Sarkaria I, Viale A, et al.(2004) Casein kinase II alpha subunit and C1-inhibitor are independent predictors of outcome in patients with squamous cell carcinoma of the lung. Clin Cancer Res 10: 5792-5803.
    • (2004) Clin Cancer Res , vol.10 , pp. 5792-5803
    • Rusch, V.1    Talbot, S.G.2    Sarkaria, I.3    Viale, A.4
  • 34
    • 1342301467 scopus 로고    scopus 로고
    • Inactivation of the Fanconi anemia/BRCA pathway in lung and oral cancers: implications for treatment and survival
    • Marsit CJ, Liu M, Nelson HH, Posner M, Suzuki M, et al.(2004) Inactivation of the Fanconi anemia/BRCA pathway in lung and oral cancers: implications for treatment and survival. Oncogene 23: 1000-1004.
    • (2004) Oncogene , vol.23 , pp. 1000-1004
    • Marsit, C.J.1    Liu, M.2    Nelson, H.H.3    Posner, M.4    Suzuki, M.5
  • 35
    • 0347988045 scopus 로고    scopus 로고
    • Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases
    • Garcia-Cao M, O'Sullivan R, Peters AH, Jenuwein T, Blasco MA, (2004) Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases. Nat Genet 36: 94-99.
    • (2004) Nat Genet , vol.36 , pp. 94-99
    • Garcia-Cao, M.1    O'Sullivan, R.2    Peters, A.H.3    Jenuwein, T.4    Blasco, M.A.5
  • 36
    • 58149177773 scopus 로고    scopus 로고
    • Tumor BRCA1, RRM1 and RRM2 mRNA expression levels and clinical response to first-line gemcitabine plus docetaxel in non-small-cell lung cancer patients
    • Boukovinas I, Papadaki C, Mendez P, Taron M, Mavroudis D, et al.(2008) Tumor BRCA1, RRM1 and RRM2 mRNA expression levels and clinical response to first-line gemcitabine plus docetaxel in non-small-cell lung cancer patients. PLoS ONE 3: e3695.
    • (2008) PLoS ONE , vol.3
    • Boukovinas, I.1    Papadaki, C.2    Mendez, P.3    Taron, M.4    Mavroudis, D.5


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