The gastric accommodation response to meal intake determines the occurrence of transient lower esophageal sphincter relaxations and reflux events in patients with gastro-esophageal reflux disease

Neurogastroenterology and Motility

Volumn 26, Issue 4, 2014, Pages 581-588

  Pauwels, A ^a   Altan, E ^a   Tack, J ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Gastric accommodation; Gastric distention; Gastro esophageal reflux disease; Reflux; Transient lower esophageal sphincter relaxations

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIGESTIVE TRACT PARAMETERS; DISEASE ASSOCIATION; GASTRIC ACCOMMODATION; GASTROESOPHAGEAL REFLUX; HUMAN; HYPOTHESIS; LOWER ESOPHAGUS SPHINCTER; LOWER ESOPHAGUS SPHINCTER PRESSURE; MEAL; MECHANORECEPTOR; MIDDLE AGED; MUSCLE RELAXATION; POSTPRANDIAL STATE; PRIORITY JOURNAL; YOUNG ADULT; ADOLESCENT; FEMALE; GASTROINTESTINAL MOTILITY; MALE; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADOLESCENT; ADULT; ESOPHAGEAL SPHINCTER, LOWER; FEMALE; GASTROESOPHAGEAL REFLUX; GASTROINTESTINAL MOTILITY; HUMANS; MALE; MIDDLE AGED; POSTPRANDIAL PERIOD; YOUNG ADULT;

EID: 84896394698     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/nmo.12305     Document Type: Article

References (50)

1. Dent J, El-Serag HB, Wallander MA, Johansson S. Epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut 2005; 54: 710-7.
2. Horn J. The proton-pump inhibitors: similarities and differences. Clin Ther 2000; 22: 266-80; discussion 5.
3. Howden CW. Appropriate acid suppression in the treatment of acid-related conditions. Pharmacol Ther 1994; 63: 123-34.
4. Raghunath AS, Hungin AP, Mason J, Jackson W. Symptoms in patients on long-term proton pump inhibitors: prevalence and predictors. Aliment Pharmacol Ther 2009; 29: 431-9.
5. Fass R, Shapiro M, Dekel R, Sewell J. Systematic review: proton-pump inhibitor failure in gastro-oesophageal reflux disease-where next? Aliment Pharmacol Ther 2005; 22: 79-94.
6. Hemmink GJ, Bredenoord AJ, Weusten BL, Mondelbaan JF, Timmer R, Smout AJ. Esophageal pH-impedance monitoring in patients with therapy-resistant reflux symptoms: 'on' or 'off' proton pump inhibitor? Am J Gastroenterol 2008; 103: 2446-53.
7. Vela MF, Camacho-Lobato L, Srinivasan R, Tutuian R, Katz PO, Castell DO. Simultaneous introesophageal impedance and pH measurement of acid and nonacid gastroesophageal reflux: effect of omeprazole. Gastroenterology 2001; 120: 1599-606.
8. Zerbib F, Roman S, Ropert A, Des Varannes SB, Parderoux P, Chaput U, Mion F, Verin E et al. Esophageal pH-impedance monitoring and symptom analysis in GERD: a study in patients off and on therapy. Am J Gastroenterol 2006; 101: 1956-63.
9. Tutuian R, Castell DO. Review article: complete gastro-oesophageal reflux monitoring - combined pH and impedance. Aliment Pharmacol Ther 2006; 24(Suppl. 2): 27-37.
10. Mainie I, Tutuian R, Shay S, Vela M, Zhang X, Sifrim D, Castell DO. Acid and non-acid reflux in patients with persistent symptoms despite acid suppressive therapy: a multicentre study using combined ambulatory impedance-pH monitoring. Gut 2006; 55: 1398-402.
11. Altan E, Blondeau K, Pauwels A, Farre R, Tack J. Evolving pharmacological approaches in gastroesophageal reflux disease. Expert Opin Emerg Drugs 2012; 17: 347-59.
12. Mittal RK, Holloway RH, Penagini R, Blackshaw LA, Dent J. Transient lower esophageal sphincter relaxation. Gastroenterology 1995; 109: 601-10.
13. Sifrim D, Holloway R. Transient lower esophageal sphincter relaxations: how many or how harmful? Am J Gastroenterol 2001; 96: 2529-32.
14. Sifrim D, Holloway R, Silny J, Tack J, Lerut A, Janssens J. Composition of the postprandial refluxate in patients with gastroesophageal reflux disease. Am J Gastroenterol 2001; 96: 647-55.
15. Bredenoord AJ, Weusten BL, Timmer R, Akkermans LM, Smout AJ. Relationships between air swallowing, intragastric air, belching and gastro-oesophageal reflux. Neurogastroenterol Motil 2005; 17: 341-7.
16. Holloway RH, Hongo M, Berger K, McCallum RW. Gastric distention: a mechanism for postprandial gastroesophageal reflux. Gastroenterology 1985; 89: 779-84.
17. Holloway RH, Kocyan P, Dent J. Provocation of transient lower esophageal sphincter relaxations by meals in patients with symptomatic gastroesophageal reflux. Dig Dis Sci 1991; 36: 1034-9.
18. Piessevaux H, Tack J, Wilmer A, Coulie B, Geutel A, Janssens J. Perception of changes in wall tension of the proximal stomach in humans. Gut 2001; 49: 203-8.
19. Kindt S, Tack J. Impaired gastric accommodation and its role in dyspepsia. Gut 2006; 55: 1685-91.
20. Janssen P, Verschueren S, Ly HG, Vos R, Van Oudenhove L, Tack J. Intragastric pressure during food intake: a physiological and minimally invasive method to assess gastric accommodation. Neurogastroenterol Motil 2011; 23: 316-22, e153-4.
21. Janssen P, Verschueren S, Tack J. Intragastric pressure as a determinant of food intake. Neurogastroenterol Motil 2012; 24: 612-5, e267-8.
22. Simonian HP, Maurer AH, Knight LC, Kantor S, Kontos D, Megalooikonomou V, Fisher RS, Parkman HP. Simultaneous assessment of gastric accommodation and emptying: studies with liquid and solid meals. J Nucl Med 2004; 45: 1155-60.
23. Tougas G, Banemai M. Gastroesophageal reflux disease pathophysiology. Chest Surg Clin N Am 2001; 11: 485-94.
24. Dent J, Holloway RH, Toouli J, Dodds WJ. Mechanisms of lower oesophageal sphincter incompetence in patients with symptomatic gastrooesophageal reflux. Gut 1988; 29: 1020-8.
25. Kahrilas PJ, Dodds WJ, Hogan WJ, Kern M, Arndorfer RC, Reece A. Esophageal peristaltic dysfunction in peptic esophagitis. Gastroenterology 1986; 91: 897-904.
26. Pandolfino JE, Kim H, Ghosh SK, Clarke JO, Zhang Q, Kahrilas PJ. High-resolution manometry of the EGJ: an analysis of crural diaphragm function in GERD. Am J Gastroenterol 2007; 102: 1056-63.
27. Holloway RH, Penagini R, Ireland AC. Criteria for objective definition of transient lower esophageal sphincter relaxation. Am J Physiol 1995; 268(1 Pt 1): G128-33.
28. Bredenoord AJ, Fox M, Kahrilas PJ, Pandolfino JE, Schwizer W, Smout AJ. Chicago classification criteria of esophageal motility disorders defined in high resolution manometry pressure topography. Neurogastroenterol Motil 2012; 24(Suppl. 1): 57-65.
29. Sifrim D, Castell D, Dent J, Kahrilas PJ. Gastro-oesophageal reflux monitoring: review and consensus report on detection and definitions of acid, non-acid, and gas reflux. Gut 2004; 53: 1024-31.
30. Mittal RK, McCallum RW. Characteristics and frequency of transient relaxations of the lower esophageal sphincter in patients with reflux esophagitis. Gastroenterology 1988; 95: 593-9.
31. Hershcovici T, Mashimo H, Fass R. The lower esophageal sphincter. Neurogastroenterol Motil 2011; 23: 819-30.
32. Wise J, Conklin JL. Gastroesophageal reflux disease and baclofen: is there a light at the end of the tunnel? Curr Gastroenterol Rep 2004; 6: 213-9.
33. Vela MF, Tutuian R, Katz PO, Castell DO. Baclofen decreases acid and non-acid post-prandial gastro-oesophageal reflux measured by combined multichannel intraluminal impedance and pH. Aliment Pharmacol Ther 2003; 17: 243-51.
34. Boeckxstaens GE, Denison H, Jensen JM, Lehmann A, Ruth M. Translational gastrointestinal pharmacology in the 21st century: 'the lesogaberan story'. Curr Opin Pharmacol 2011; 11: 630-3.
35. Tack J. Functional dyspepsia: impaired fundic accommodation. Curr Treat Options Gastroenterol 2000; 3: 287-94.
36. Frankhuisen R, Van Hervwaarden MA, Scheffer R, Hebbard GS, Gooszen HG, Samsom M. Increased intragastric pressure gradients are involved in the occurrence of acid reflux in gastroesophageal reflux disease. Scand J Gastroenterol 2009; 44: 545-50.
37. Blondeau K, Boecxstaens V, Van Oudenhove L, Farre R, Boeckstaens G, Tack J. Increasing body weight enhances prevalence and proximal extent of reflux in GERD patients 'on' and 'off' PPI therapy. Neurogastroenterol Motil 2011; 23: 724-e327.
38. Tefera S, Gilja OH, Olafsdottir E, Hausken T, Hatlebakk JG, Berstad A. Intragastric maldistribution of a liquid meal in patients with reflux oesophagitis assessed by three dimensional ultrasonography. Gut 2002; 50: 153-8.
39. Alonso O, Hernandez D, Moreno E, Manrique A, Moreno A, Garcia-Sesma A, Calvo J. The real value of lower esophageal sphincter measurement for predicting acid gastroesophageal reflux or Barrett's esophagus. J Gastrointest Surg 2005; 9: 973-9.
40. Katzka DA, Sidhu M, Castell DO. Hypertensive lower esophageal sphincter pressures and gastroesophageal reflux: an apparent paradox that is not unusual. Am J Gastroenterol 1995; 90: 280-4.
41. Katada N, Hinder RA, Hinder PR, Lund RJ, Perdikis G, Stalzer RA, McGinn TR. The hypertensive lower esophageal sphincter. Am J Surg 1996; 172: 439-42; discussion 42-3.
42. Fein M, Ritter MP, DeMeester TR, Oberg S, Peters JH, Hagen JA, Bremner CG. Role of the lower esophageal sphincter and hiatal hernia in the pathogenesis of gastroesophageal reflux disease. J Gastrointest Surg 1999; 3: 405-10.
43. Penagini R, Hebbard G, Horowitz M, Dent J, Berminghan H, Jones K, Holloway RH. Motor function of the proximal stomach and visceral perception in gastro-oesophageal reflux disease. Gut 1998; 42: 251-7.
44. Lidums I, Checklin H, Mittal RK, Holloway RH. Effect of atropine on gastro-oesophageal reflux and transient lower oesophageal sphincter relaxations in patients with gastro-oesophageal reflux disease. Gut 1998; 43: 12-6.
45. Zerbib F, Bruley Des Varannes S, Scarpignato C, Leray V, D'Amato M, Roze C, Galmiche JP. Endogenous cholecystokinin in postprandial lower esophageal sphincter function and fundic tone in humans. Am J Physiol 1998;275(6 Pt 1):G1266-73.
46. Penagini R, Carmagnola S, Cantù P, Allocca M, Bianchi PA. Mechanoreceptors of the proximal stomach: role in triggering transient lower esophageal sphincter relaxation. Gastroenterology 2004; 126: 49-56.
47. Penagini R, Allocca M, Cantù P, Mangano M, Savojardo D, Carmagnola S, Bianchi PA. Relationship between motor function of the proximal stomach and transient lower oesophageal sphincter relaxation after morphine. Gut 2004; 53: 1227-31.
48. Tutuian R, Vos R, Karamanolis G, Tack J. An audit of technical pitfalls of gastric barostat testing in dyspepsia. Neurogastroenterol Motil 2008; 20: 113-8.
49. Mundt MW, Hausken T, Samsom M. Effect of intragastric barostat bag on proximal and distal gastric accommodation in response to liquid meal. Am J Physiol Gastrointest Liver Physiol 2002; 283: G681-6.
50. Piessevaux H, De Winter B, Louis E, Muls V, De Looze D, Pelckmans P, Deltenre M, Urbain D et al. Dyspeptic symptoms in the general population: a factor and cluster analysis of symptom groupings. Neurogastroenterol Motil 2009; 21: 378-88.