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Volumn 6, Issue 3, 2004, Pages 213-219

Gastroesophageal reflux disease and baclofen: Is there a light at the end of the tunnel?

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR STIMULATING AGENT; 4 AMINOBUTYRIC ACID DERIVATIVE; ACID; ATROPINE; BACLOFEN; CHOLECYSTOKININ A RECEPTOR ANTAGONIST; GLUTAMIC ACID; MORPHINE; NITRIC OXIDE SYNTHASE INHIBITOR; PLACEBO; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT;

EID: 4544220343     PISSN: 15228037     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11894-004-0010-9     Document Type: Review
Times cited : (16)

References (47)
  • 1
    • 0028954543 scopus 로고
    • Inhibition of resting lower esophageal sphincter pressure by pharyngeal water stimulation in humans
    • Trifan A, Shaker R, Ren J, et al.: Inhibition of resting lower esophageal sphincter pressure by pharyngeal water stimulation in humans. Gastroenterology 1995, 108: 441-446.
    • (1995) Gastroenterology , vol.108 , pp. 441-446
    • Trifan, A.1    Shaker, R.2    Ren, J.3
  • 2
    • 0033910051 scopus 로고    scopus 로고
    • The effect of mechanoreceptor stimulation of the laryngopharynx on the oesophago-gastric junction
    • Noordzij JP, Mittal RK, Arora T, et al.: The effect of mechanoreceptor stimulation of the laryngopharynx on the oesophago-gastric junction. Neurogastroenterol Motil 2000, 12: 353-359.
    • (2000) Neurogastroenterol. Motil. , vol.12 , pp. 353-359
    • Noordzij, J.P.1    Mittal, R.K.2    Arora, T.3
  • 3
    • 0023948294 scopus 로고
    • Factors that influence induction of gastroesophageal reflux in normal human subjects
    • Dent J, Dodds WJ, Hogan WJ, Toouli J: Factors that influence induction of gastroesophageal reflux in normal human subjects Dig Dis Sci 1988, 33: 270-275.
    • (1988) Dig. Dis. Sci. , vol.33 , pp. 270-275
    • Dent, J.1    Dodds, W.J.2    Hogan, W.J.3    Toouli, J.4
  • 4
    • 0011891167 scopus 로고    scopus 로고
    • Esophageal distention: An unsuspected trigger mechanism for gastroesophageal reflux
    • Xie P-Y, Barden E, Ren J, et al.: Esophageal distention: an unsuspected trigger mechanism for gastroesophageal reflux. J Beijing Med Univ 2000, 32: 121-122.
    • (2000) J. Beijing Med. Univ. , vol.32 , pp. 121-122
    • Xie, P.-Y.1    Barden, E.2    Ren, J.3
  • 5
    • 0029102811 scopus 로고
    • Transient lower esophageal sphincter relaxation
    • Mittal RK, Holloway RH, Penagini R, et al.: Transient lower esophageal sphincter relaxation. Gastroenterology 1995, 109: 601-610.
    • (1995) Gastroenterology , vol.109 , pp. 601-610
    • Mittal, R.K.1    Holloway, R.H.2    Penagini, R.3
  • 6
    • 0022448804 scopus 로고
    • Abolition of gas reflux and transient lower esophageal sphincter relaxation by vagal blockade in the dog
    • Martin CJ, Patrikios J, Dent J: Abolition of gas reflux and transient lower esophageal sphincter relaxation by vagal blockade in the dog. Gastroenterology 1986, 81: 890-896.
    • (1986) Gastroenterology , vol.81 , pp. 890-896
    • Martin, C.J.1    Patrikios, J.2    Dent, J.3
  • 7
    • 0025182186 scopus 로고
    • Response of canine lower esophageal sphincter to gastric distention
    • Franzi SJ, Martin CJ, Cox MR, Dent J: Response of canine lower esophageal sphincter to gastric distention. Am J Physiol 1990, 259: G380-G385.
    • (1990) Am. J. Physiol. , vol.259
    • Franzi, S.J.1    Martin, C.J.2    Cox, M.R.3    Dent, J.4
  • 8
    • 0032192137 scopus 로고    scopus 로고
    • Vagally evoked synaptic currents in the immature rat nucleus tractus solitarii in an intact in vitro preparation
    • Smith BN, Dou P, Barber WD, Dudek FE: Vagally evoked synaptic currents in the immature rat nucleus tractus solitarii in an intact in vitro preparation. J Physiol 1998, 512: 149-162.
    • (1998) J. Physiol. , vol.512 , pp. 149-162
    • Smith, B.N.1    Dou, P.2    Barber, W.D.3    Dudek, F.E.4
  • 9
    • 0036016838 scopus 로고    scopus 로고
    • Lower esophageal sphincter relaxation evoked by stimulation of the dorsal motor nucleus of the vagus in ferrets
    • Abrahams TP, Partosoedarso ER, Hornby PJ: Lower esophageal sphincter relaxation evoked by stimulation of the dorsal motor nucleus of the vagus in ferrets. Neurogastroenterol Motil 2002, 14: 295-304.
    • (2002) Neurogastroenterol. Motil. , vol.14 , pp. 295-304
    • Abrahams, T.P.1    Partosoedarso, E.R.2    Hornby, P.J.3
  • 10
    • 0034743929 scopus 로고    scopus 로고
    • Site of action of GABAB receptor for vagal motor control of lower esophageal sphincter in ferrets and rats
    • McDermott CM, Abrahams TP, Partosoedarso ER, et al.: Site of action of GABAB receptor for vagal motor control of lower esophageal sphincter in ferrets and rats. Gastroenterology 2001, 120: 1749-1762.
    • (2001) Gastroenterology , vol.120 , pp. 1749-1762
    • McDermott, C.M.1    Abrahams, T.P.2    Partosoedarso, E.R.3
  • 11
    • 0021245825 scopus 로고
    • Effect of hindbrain stimulation on lower esophageal sphincter pressure in cats
    • Barone FC, Lombardi DM, Ormsbee HIS: Effect of hindbrain stimulation on lower esophageal sphincter pressure in cats. Am J Physiol 1984, 217: G70-G78.
    • (1984) Am. J. Physiol. , vol.217
    • Barone, F.C.1    Lombardi, D.M.2    Ormsbee, H.I.S.3
  • 12
    • 0023232541 scopus 로고
    • Response of feline gastroesophageal junction to changes in abdominal pressure
    • Boyle JT, Altschuler SM, Nixon TE, et al.: Response of feline gastroesophageal junction to changes in abdominal pressure. Am J Physiol 1987, 253: G315-G322.
    • (1987) Am. J. Physiol. , vol.253
    • Boyle, J.T.1    Altschuler, S.M.2    Nixon, T.E.3
  • 13
    • 5444245094 scopus 로고    scopus 로고
    • Cholinergic blockade inhibits gastroesophageal reflux and transient lower esophageal sphincter relaxation through a central mechanism
    • Fang JC, Sarosiek I, Yamamoto Y, et al.: Cholinergic blockade inhibits gastroesophageal reflux and transient lower esophageal sphincter relaxation through a central mechanism. Gut 1998, 115: 1374-1380.
    • (1998) Gut , vol.115 , pp. 1374-1380
    • Fang, J.C.1    Sarosiek, I.2    Yamamoto, Y.3
  • 14
    • 0025946754 scopus 로고
    • Nitric oxide: Mediator of nonadrenergic noncholinergic responses of opossum esophageal muscle
    • Murray J, Du C, Ledlow A, et al.: Nitric oxide: mediator of nonadrenergic noncholinergic responses of opossum esophageal muscle. Am J Physiol 1991, 261: G401-G406.
    • (1991) Am. J. Physiol. , vol.261
    • Murray, J.1    Du, C.2    Ledlow, A.3
  • 15
    • 0025848943 scopus 로고
    • Nitric oxide mediating NANC inhibition in opossum lower esophageal sphincter
    • Tottrup A, Svane D, Forman A: Nitric oxide mediating NANC inhibition in opossum lower esophageal sphincter. Am J Physiol 1991, 260: G385-G389.
    • (1991) Am. J. Physiol. , vol.260
    • Tottrup, A.1    Svane, D.2    Forman, A.3
  • 16
    • 0021261121 scopus 로고
    • Vasoactive intestinal polypeptide: A neurotransmitter for lower esophageal sphincter
    • Biancani P, Walsh JH, Behar J: Vasoactive intestinal polypeptide: a neurotransmitter for lower esophageal sphincter. J Clin Invest 1984, 73: 963-967.
    • (1984) J. Clin. Invest. , vol.73 , pp. 963-967
    • Biancani, P.1    Walsh, J.H.2    Behar, J.3
  • 17
    • 0034139797 scopus 로고    scopus 로고
    • Recent advances in GABAB receptors: From pharmacology to molecular biology
    • Ong J, Kerr DI: Recent advances in GABAB receptors: from pharmacology to molecular biology. Acta Pharmacol Sin 2000, 21: 111-123.
    • (2000) Acta Pharmacol. Sin. , vol.21 , pp. 111-123
    • Ong, J.1    Kerr, D.I.2
  • 18
    • 0035661904 scopus 로고    scopus 로고
    • GABA(B)R expressed on vagal afferent neurons inhibit gastric mechanosensitivity in ferret proximal stomach
    • Smid DS, Young RL, Cooper NJ, Blackshaw LA: GABA(B)R expressed on vagal afferent neurons inhibit gastric mechanosensitivity in ferret proximal stomach. Am J Physiol 2001, 281: G1494-G1501.
    • (2001) Am. J. Physiol. , vol.281
    • Smid, D.S.1    Young, R.L.2    Cooper, N.J.3    Blackshaw, L.A.4
  • 19
    • 0037195495 scopus 로고    scopus 로고
    • Functional GABAB receptors are present on the guinea pig nodose ganglion cell bodies but not in peripheral mechanosensitive ends
    • Zagorodnyuk VP, D'Antona G, Brooks SJ, Costa M: Functional GABAB receptors are present on the guinea pig nodose ganglion cell bodies but not in peripheral mechanosensitive ends. Auton Neurosci 2002, 102: 20-29.
    • (2002) Auton. Neurosci. , vol.102 , pp. 20-29
    • Zagorodnyuk, V.P.1    D'Antona, G.2    Brooks, S.J.3    Costa, M.4
  • 20
    • 0035015204 scopus 로고    scopus 로고
    • GABAB receptors on vagal afferent pathways: Peripheral and central inhibition
    • Partosoedarso ER, Young RL, Blackshaw LA: GABAB receptors on vagal afferent pathways: peripheral and central inhibition. Am J Physiol 2001, 280: G658-G668.
    • (2001) Am. J. Physiol. , vol.280
    • Partosoedarso, E.R.1    Young, R.L.2    Blackshaw, L.A.3
  • 21
    • 0033215989 scopus 로고    scopus 로고
    • GABAB receptors inhibit mechanosensitivity of primary afferent endings
    • Page AJ, Blackshaw LA: GABAB receptors inhibit mechanosensitivity of primary afferent endings. J Neurosci 1999, 19: 8597-8602.
    • (1999) J. Neurosci. , vol.19 , pp. 8597-8602
    • Page, A.J.1    Blackshaw, L.A.2
  • 22
    • 0026491095 scopus 로고
    • The actions of baclofen on neurons and synaptic transmission in the nucleus tractus solitarii of the rat in vitro
    • Brooks PA, Glaum SR, Miller RJ, Spyer KM: The actions of baclofen on neurons and synaptic transmission in the nucleus tractus solitarii of the rat in vitro. J Physiol 1992, 457: 115-129.
    • (1992) J. Physiol. , vol.457 , pp. 115-129
    • Brooks, P.A.1    Glaum, S.R.2    Miller, R.J.3    Spyer, K.M.4
  • 23
    • 0034966983 scopus 로고    scopus 로고
    • Mechanism of action of baclofen in rat dorsal motor nucleus of the vagus
    • Browning KN, Travagli RA: Mechanism of action of baclofen in rat dorsal motor nucleus of the vagus. Am J Physiol 2001, 280: G1106-G1113.
    • (2001) Am. J. Physiol. , vol.280
    • Browning, K.N.1    Travagli, R.A.2
  • 24
    • 0033780580 scopus 로고    scopus 로고
    • Vagal transmission to the ferret lower oesophageal sphincter: Inhibition by GABA(B) receptors
    • Smid DS, Blackshaw LA: Vagal transmission to the ferret lower oesophageal sphincter: inhibition by GABA(B) receptors. Br J Pharmacol 2000, 131: 624-630.
    • (2000) Br. J. Pharmacol. , vol.131 , pp. 624-630
    • Smid, D.S.1    Blackshaw, L.A.2
  • 25
  • 26
    • 0022644267 scopus 로고
    • Relationship of transient lower esophageal sphincter relaxation to postprandial gastroesophageal reflux and belching in dogs
    • Patrikios J, Martin CJ, Dent J: Relationship of transient lower esophageal sphincter relaxation to postprandial gastroesophageal reflux and belching in dogs. Gastroenterology 1986, 90: 545-551.
    • (1986) Gastroenterology , vol.90 , pp. 545-551
    • Patrikios, J.1    Martin, C.J.2    Dent, J.3
  • 27
    • 0032692271 scopus 로고    scopus 로고
    • Activation of the GABA(B) receptor inhibits transient lower esophageal sphincter relaxations in dogs
    • Lehmann A, Antonsson M, Bremer-Danielsen M, et al.: Activation of the GABA(B) receptor inhibits transient lower esophageal sphincter relaxations in dogs. Gastroenterology 1999, 117: 1147-1154.
    • (1999) Gastroenterology , vol.117 , pp. 1147-1154
    • Lehmann, A.1    Antonsson, M.2    Bremer-Danielsen, M.3
  • 30
    • 0032720273 scopus 로고    scopus 로고
    • Inhibition of transient LES relaxations and reflux by GABA receptor agonists
    • Blackshaw LA, Staunton D, Lehmann A, Dent J: Inhibition of transient LES relaxations and reflux by GABA receptor agonists. Am J Physiol 1999, 277: G867-G874.
    • (1999) Am. J. Physiol. , vol.277
    • Blackshaw, L.A.1    Staunton, D.2    Lehmann, A.3    Dent, J.4
  • 31
    • 0036889719 scopus 로고    scopus 로고
    • Baclofen blocks LES relaxation and crural diaphragm inhibition by esophageal and gastric distention in cats
    • Liu J, Pehlivanova N, Mittal RK: Baclofen blocks LES relaxation and crural diaphragm inhibition by esophageal and gastric distention in cats. Am J Physiol 2002, 283: G1276-GI281.
    • (2002) Am. J. Physiol. , vol.283
    • Liu, J.1    Pehlivanova, N.2    Mittal, R.K.3
  • 32
    • 0020458289 scopus 로고
    • Mechanisms of gastroesophageal reflux in patients with reflux esophagitis
    • Dodds WJ, Dent J, Hogan WJ, et al.: Mechanisms of gastroesophageal reflux in patients with reflux esophagitis. N Eng J Med 1982, 301: 1547-1552.
    • (1982) N. Eng. J. Med. , vol.301 , pp. 1547-1552
    • Dodds, W.J.1    Dent, J.2    Hogan, W.J.3
  • 33
    • 0028789247 scopus 로고
    • Effect of atropine on the frequency of reflux and transient lower esophageal sphincter relaxation in normal subjects
    • Mittal RK, Holloway R, Dent J: Effect of atropine on the frequency of reflux and transient lower esophageal sphincter relaxation in normal subjects. Gastroenterology 1995, 109: 1547-1554.
    • (1995) Gastroenterology , vol.109 , pp. 1547-1554
    • Mittal, R.K.1    Holloway, R.2    Dent, J.3
  • 34
    • 0030882177 scopus 로고    scopus 로고
    • Atropine inhibits gastric distension and pharyngeal receptor mediated lower oesophageal sphincter relaxation
    • Mittal RK, Chiareli C, Liu J, et al.: Atropine inhibits gastric distension and pharyngeal receptor mediated lower oesophageal sphincter relaxation. Gut 1997, 41: 285-290.
    • (1997) Gut , vol.41 , pp. 285-290
    • Mittal, R.K.1    Chiareli, C.2    Liu, J.3
  • 35
    • 0030753734 scopus 로고    scopus 로고
    • Effect of morphine on gastroesophageal reflux and transient lower esophageal sphincter relaxation
    • Penagini R, Bianchi PA: Effect of morphine on gastroesophageal reflux and transient lower esophageal sphincter relaxation. Gastroenterology 1997, 113: 409-414.
    • (1997) Gastroenterology , vol.113 , pp. 409-414
    • Penagini, R.1    Bianchi, P.A.2
  • 36
    • 0036124689 scopus 로고    scopus 로고
    • Is glutamate involved in transient lower esophageal sphincter relaxations?
    • Hirsch DP, Tytgat GN, Boeckxstaens GE: Is glutamate involved in transient lower esophageal sphincter relaxations? Dig Dis Sci 2002, 47: 661-666.
    • (2002) Dig. Dis. Sci. , vol.47 , pp. 661-666
    • Hirsch, D.P.1    Tytgat, G.N.2    Boeckxstaens, G.E.3
  • 37
    • 0032219474 scopus 로고    scopus 로고
    • Involvement of cholecystokininA receptors in transient lower esophageal sphincter relaxations triggered by gastric distension
    • Boeckxstaens GE, Hirsch DP, Fakhry N, et al.: Involvement of cholecystokininA receptors in transient lower esophageal sphincter relaxations triggered by gastric distension. Am J Gastroenterol 1998, 93: 1823-1828.
    • (1998) Am. J. Gastroenterol. , vol.93 , pp. 1823-1828
    • Boeckxstaens, G.E.1    Hirsch, D.P.2    Fakhry, N.3
  • 38
    • 0033732230 scopus 로고    scopus 로고
    • Effect of L-NMMA on postprandial transient lower esophageal sphincter relaxations in healthy volunteers
    • Hirsh DP, Tiel-Van Buul MM, Tytgat GN, Boeckxstaens GE: Effect of L-NMMA on postprandial transient lower esophageal sphincter relaxations in healthy volunteers. Dig Dis Sci 2000, 45: 2069-2075.
    • (2000) Dig. Dis. Sci. , vol.45 , pp. 2069-2075
    • Hirsh, D.P.1    Tiel-Van Buul, M.M.2    Tytgat, G.N.3    Boeckxstaens, G.E.4
  • 39
    • 0033958395 scopus 로고    scopus 로고
    • Control of transient lower esophageal sphincter relaxations and reflux by the GABA(B) agonist baclofen in normal subjects
    • Lidums I, Lehmann A, Checklin H, et al.: Control of transient lower esophageal sphincter relaxations and reflux by the GABA(B) agonist baclofen in normal subjects. Gastroenterology 2000, 118: 7-13.
    • (2000) Gastroenterology , vol.118 , pp. 7-13
    • Lidums, I.1    Lehmann, A.2    Checklin, H.3
  • 40
    • 0036136088 scopus 로고    scopus 로고
    • Control of transient lower oesophageal sphincter relaxations and reflux by the GABA(B) agonist baclofen in patients with gastro-oesophageal reflux disease
    • Zhang Q, Lehmann A, Rigda R, et al.: Control of transient lower oesophageal sphincter relaxations and reflux by the GABA(B) agonist baclofen in patients with gastro-oesophageal reflux disease. Gut 2002, 50: 19-24.
    • (2002) Gut , vol.50 , pp. 19-24
    • Zhang, Q.1    Lehmann, A.2    Rigda, R.3
  • 41
    • 0036735045 scopus 로고    scopus 로고
    • The effect of baclofen on gastro-oesophageal reflux, lower oesophageal sphincter function and reflux symptoms in patients with reflux disease
    • van Herwaarden MA, Samsom M, Rydholm H, Smout AJ: The effect of baclofen on gastro-oesophageal reflux, lower oesophageal sphincter function and reflux symptoms in patients with reflux disease. Aliment Pharmacol Ther 2002, 16: 1655-1662.
    • (2002) Aliment. Pharmacol. Ther. , vol.16 , pp. 1655-1662
    • van Herwaarden, M.A.1    Samsom, M.2    Rydholm, H.3    Smout, A.J.4
  • 42
    • 0347708695 scopus 로고    scopus 로고
    • Baclofen decreases acid and non-acid post-prandial gastro-oesophageal reflux measured by combined multichannel intraluminal impedance and pH
    • Vela MF, Tutuian R, Katz PO, Castell DO: Baclofen decreases acid and non-acid post-prandial gastro-oesophageal reflux measured by combined multichannel intraluminal impedance and pH. Aliment Pharmacol Ther 2003, 17: 243-251.
    • (2003) Aliment. Pharmacol. Ther. , vol.17 , pp. 243-251
    • Vela, M.F.1    Tutuian, R.2    Katz, P.O.3    Castell, D.O.4
  • 43
    • 0036240152 scopus 로고    scopus 로고
    • Baclofen-mediated gastro-oesophageal acid reflux control in patients with established reflux disease
    • Cange L, Johnsson E, Rydholm H, et al.: Baclofen-mediated gastro-oesophageal acid reflux control in patients with established reflux disease. Aliment Pharmacol Ther 2002, 16: 869-873.
    • (2002) Aliment. Pharmacol. Ther. , vol.16 , pp. 869-873
    • Cange, L.1    Johnsson, E.2    Rydholm, H.3
  • 44
    • 0242500869 scopus 로고    scopus 로고
    • Effect of acute and chronic administration of the GABA B agonist baclofen on 24 hour pH metry and symptoms in control subjects and in patients with gastro-oesophageal reflux disease
    • Ciccaglione AF, Marzio L: Effect of acute and chronic administration of the GABA B agonist baclofen on 24 hour pH metry and symptoms in control subjects and in patients with gastro-oesophageal reflux disease. Gut 2003, 52: 464-470.
    • (2003) Gut , vol.52 , pp. 464-470
    • Ciccaglione, A.F.1    Marzio, L.2
  • 45
    • 5444240297 scopus 로고    scopus 로고
    • Effects of baclofen on patients with gastroesophageal reflux disease: A prospective randomized, double-blinded, placebo-controlled study
    • [abstract]
    • Cossentino MJ, Maydonovitch C, Belle L, Wong RKH: Effects of baclofen on patients with gastroesophageal reflux disease: a prospective randomized, double-blinded, placebo-controlled study [abstract]. Gastroenterology 2003, 124(Suppl 1): A226.
    • (2003) Gastroenterology , vol.124 , Issue.SUPPL. 1
    • Cossentino, M.J.1    Maydonovitch, C.2    Belle, L.3    Wong, R.K.H.4
  • 46
    • 0141757445 scopus 로고    scopus 로고
    • Effect of the GABA(B) agonist baclofen in patients with symptoms and duodenogastro-oesophageal reflux refractory to proton pump inhibitors
    • Koek GH, Sifrim D, Lerut T, et al.: Effect of the GABA(B) agonist baclofen in patients with symptoms and duodenogastro-oesophageal reflux refractory to proton pump inhibitors. Gut 2003, 52: 1397-1402.
    • (2003) Gut , vol.52 , pp. 1397-1402
    • Koek, G.H.1    Sifrim, D.2    Lerut, T.3
  • 47
    • 0043109661 scopus 로고    scopus 로고
    • Lioresal (Novanis). Montvale, NJ: Medical Economics
    • Lioresal (Novanis). In Physicians' Desk Reference. Montvale, NJ: Medical Economics; 1997:847-848.
    • (1997) Physicians' Desk Reference. , pp. 847-848


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