7,8-dihydroxyflavone, a small-molecule tropomyosin-related kinase B (TrkB) agonist, attenuates cerebral ischemia and reperfusion injury in rats

Journal of Molecular Histology

Volumn 45, Issue 2, 2014, Pages 129-140

  Wang, Bing ^a,b   Wu, Nan ^b   Liang, Feng ^b   Zhang, Shuqin ^b   Ni, Weimin ^b   Cao, Yunxing ^b   Xia, Dongjian ^b   Xi, Huanjiu ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b JINZHOU MEDICAL UNIVERSITY   (China)

Author keywords

7,8 dihydroxyflavone; Apoptosis; Cerebral ischemia and reperfusion injury; Inducible nitric oxide synthase; Nuclear factor B; Oxidative stress

Indexed keywords

7,8 DIHYDROXYFLAVONE; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CASPASE 3; GLUTATHIONE; GLUTATHIONE PEROXIDASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MALONALDEHYDE; NITRIC OXIDE; PROTEIN BAX; PROTEIN BCL 2; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BINDING AFFINITY; BRAIN ISCHEMIA; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVITY; HISTOLOGY; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; UPREGULATION;

RATTUS;

ANIMALS; DRUG EVALUATION, PRECLINICAL; ENZYME ACTIVATION; ENZYME ACTIVATORS; FLAVONES; GLUTATHIONE; GLUTATHIONE PEROXIDASE; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MALONDIALDEHYDE; NITRIC OXIDE; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, TRKB; REPERFUSION INJURY; SUPEROXIDE DISMUTASE;

EID: 84896394611     PISSN: 15672379     EISSN: 15672387     Source Type: Journal    
DOI: 10.1007/s10735-013-9539-y     Document Type: Article

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