-
1
-
-
82955233157
-
The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks
-
Acs K., Luijsterburg M.S., Ackermann L., Salomons F.A., Hoppe T., Dantuma N.P. The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks. Nat. Struct. Mol. Biol. 2011, 18:1345-1350.
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 1345-1350
-
-
Acs, K.1
Luijsterburg, M.S.2
Ackermann, L.3
Salomons, F.A.4
Hoppe, T.5
Dantuma, N.P.6
-
2
-
-
52049114924
-
Physical and functional interactions of monoubiquitylated transactivators with the proteasome
-
Archer C.T., Burdine L., Liu B., Ferdous A., Johnston S.A., Kodadek T. Physical and functional interactions of monoubiquitylated transactivators with the proteasome. J.Biol. Chem. 2008, 283:21789-21798.
-
(2008)
J.Biol. Chem.
, vol.283
, pp. 21789-21798
-
-
Archer, C.T.1
Burdine, L.2
Liu, B.3
Ferdous, A.4
Johnston, S.A.5
Kodadek, T.6
-
3
-
-
0023003380
-
Invivo half-life of a protein is a function of its amino-terminal residue
-
Bachmair A., Finley D., Varshavsky A. Invivo half-life of a protein is a function of its amino-terminal residue. Science 1986, 234:179-186.
-
(1986)
Science
, vol.234
, pp. 179-186
-
-
Bachmair, A.1
Finley, D.2
Varshavsky, A.3
-
4
-
-
84877585813
-
Role of Cdc48/p97 as a SUMO-targeted segregase curbing Rad51-Rad52 interaction
-
Bergink S., Ammon T., Kern M., Schermelleh L., Leonhardt H., Jentsch S. Role of Cdc48/p97 as a SUMO-targeted segregase curbing Rad51-Rad52 interaction. Nat. Cell Biol. 2013, 15:526-532.
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 526-532
-
-
Bergink, S.1
Ammon, T.2
Kern, M.3
Schermelleh, L.4
Leonhardt, H.5
Jentsch, S.6
-
5
-
-
79953171555
-
Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways
-
Chou T.F., Brown S.J., Minond D., Nordin B.E., Li K., Jones A.C., Chase P., Porubsky P.R., Stoltz B.M., Schoenen F.J., et al. Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways. Proc. Natl. Acad. Sci. USA 2011, 108:4834-4839.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 4834-4839
-
-
Chou, T.F.1
Brown, S.J.2
Minond, D.3
Nordin, B.E.4
Li, K.5
Jones, A.C.6
Chase, P.7
Porubsky, P.R.8
Stoltz, B.M.9
Schoenen, F.J.10
-
6
-
-
0031908629
-
A new LexA-based genetic system for monitoring and analyzing protein heterodimerization in Escherichia coli
-
Dmitrova M., Younes-Cauet G., Oertel-Buchheit P., Porte D., Schnarr M., Granger-Schnarr M. A new LexA-based genetic system for monitoring and analyzing protein heterodimerization in Escherichia coli. Mol. Gen. Genet. 1998, 257:205-212.
-
(1998)
Mol. Gen. Genet.
, vol.257
, pp. 205-212
-
-
Dmitrova, M.1
Younes-Cauet, G.2
Oertel-Buchheit, P.3
Porte, D.4
Schnarr, M.5
Granger-Schnarr, M.6
-
7
-
-
33846132939
-
The role of the proteasomal ATPases and activator monoubiquitylation in regulating Gal4 binding to promoters
-
Ferdous A., Sikder D., Gillette T., Nalley K., Kodadek T., Johnston S.A. The role of the proteasomal ATPases and activator monoubiquitylation in regulating Gal4 binding to promoters. Genes Dev. 2007, 21:112-123.
-
(2007)
Genes Dev.
, vol.21
, pp. 112-123
-
-
Ferdous, A.1
Sikder, D.2
Gillette, T.3
Nalley, K.4
Kodadek, T.5
Johnston, S.A.6
-
8
-
-
3242696232
-
Proteolysis-independent regulation of the transcription factor Met4 by a single Lys 48-linked ubiquitin chain
-
Flick K., Ouni I., Wohlschlegel J.A., Capati C., McDonald W.H., Yates J.R., Kaiser P. Proteolysis-independent regulation of the transcription factor Met4 by a single Lys 48-linked ubiquitin chain. Nat. Cell Biol. 2004, 6:634-641.
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 634-641
-
-
Flick, K.1
Ouni, I.2
Wohlschlegel, J.A.3
Capati, C.4
McDonald, W.H.5
Yates, J.R.6
Kaiser, P.7
-
9
-
-
70350785179
-
Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling
-
Gao S., Alarcon C., Sapkota G., Rahman S., Chen P.Y., Goerner N., Macias M.J., Erdjument-Bromage H., Tempst P., Massague J. Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling. Mol. Cell 2009, 36:457-468.
-
(2009)
Mol. Cell
, vol.36
, pp. 457-468
-
-
Gao, S.1
Alarcon, C.2
Sapkota, G.3
Rahman, S.4
Chen, P.Y.5
Goerner, N.6
Macias, M.J.7
Erdjument-Bromage, H.8
Tempst, P.9
Massague, J.10
-
11
-
-
14244260623
-
Defining the SUMO-modified proteome by multiple approaches in Saccharomyces cerevisiae
-
Hannich J.T., Lewis A., Kroetz M.B., Li S.J., Heide H., Emili A., Hochstrasser M. Defining the SUMO-modified proteome by multiple approaches in Saccharomyces cerevisiae. J.Biol. Chem. 2005, 280:4102-4110.
-
(2005)
J.Biol. Chem.
, vol.280
, pp. 4102-4110
-
-
Hannich, J.T.1
Lewis, A.2
Kroetz, M.B.3
Li, S.J.4
Heide, H.5
Emili, A.6
Hochstrasser, M.7
-
13
-
-
80455143831
-
USP15 is a deubiquitylating enzyme for receptor-activated SMADs
-
Inui M., Manfrin A., Mamidi A., Martello G., Morsut L., Soligo S., Enzo E., Moro S., Polo S., Dupont S., et al. USP15 is a deubiquitylating enzyme for receptor-activated SMADs. Nat. Cell Biol. 2011, 13:1368-1375.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 1368-1375
-
-
Inui, M.1
Manfrin, A.2
Mamidi, A.3
Martello, G.4
Morsut, L.5
Soligo, S.6
Enzo, E.7
Moro, S.8
Polo, S.9
Dupont, S.10
-
14
-
-
33845939821
-
Cdc48 (p97): a "molecular gearbox" in the ubiquitin pathway?
-
Jentsch S., Rumpf S. Cdc48 (p97): a "molecular gearbox" in the ubiquitin pathway?. Trends Biochem. Sci. 2007, 32:6-11.
-
(2007)
Trends Biochem. Sci.
, vol.32
, pp. 6-11
-
-
Jentsch, S.1
Rumpf, S.2
-
15
-
-
0034604341
-
Regulation of transcription by ubiquitination without proteolysis: Cdc34/SCF(Met30)-mediated inactivation of the transcription factor Met4
-
Kaiser P., Flick K., Wittenberg C., Reed S.I. Regulation of transcription by ubiquitination without proteolysis: Cdc34/SCF(Met30)-mediated inactivation of the transcription factor Met4. Cell 2000, 102:303-314.
-
(2000)
Cell
, vol.102
, pp. 303-314
-
-
Kaiser, P.1
Flick, K.2
Wittenberg, C.3
Reed, S.I.4
-
16
-
-
76049086964
-
Dissection of combinatorial control by the Met4 transcriptional complex
-
Lee T.A., Jorgensen P., Bognar A.L., Peyraud C., Thomas D., Tyers M. Dissection of combinatorial control by the Met4 transcriptional complex. Mol. Biol. Cell 2010, 21:456-469.
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 456-469
-
-
Lee, T.A.1
Jorgensen, P.2
Bognar, A.L.3
Peyraud, C.4
Thomas, D.5
Tyers, M.6
-
17
-
-
0348134742
-
Mono- versus polyubiquitination: differential control of p53 fate by Mdm2
-
Li M., Brooks C.L., Wu-Baer F., Chen D., Baer R., Gu W. Mono- versus polyubiquitination: differential control of p53 fate by Mdm2. Science 2003, 302:1972-1975.
-
(2003)
Science
, vol.302
, pp. 1972-1975
-
-
Li, M.1
Brooks, C.L.2
Wu-Baer, F.3
Chen, D.4
Baer, R.5
Gu, W.6
-
18
-
-
27744495040
-
A putative stimulatory role for activator turnover in gene expression
-
Lipford J.R., Smith G.T., Chi Y., Deshaies R.J. A putative stimulatory role for activator turnover in gene expression. Nature 2005, 438:113-116.
-
(2005)
Nature
, vol.438
, pp. 113-116
-
-
Lipford, J.R.1
Smith, G.T.2
Chi, Y.3
Deshaies, R.J.4
-
19
-
-
80455145246
-
The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks
-
Meerang M., Ritz D., Paliwal S., Garajova Z., Bosshard M., Mailand N., Janscak P., Hubscher U., Meyer H., Ramadan K. The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks. Nat. Cell Biol. 2011, 13:1376-1382.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 1376-1382
-
-
Meerang, M.1
Ritz, D.2
Paliwal, S.3
Garajova, Z.4
Bosshard, M.5
Mailand, N.6
Janscak, P.7
Hubscher, U.8
Meyer, H.9
Ramadan, K.10
-
20
-
-
84865475874
-
Dual recruitment of Cdc48 (p97)-Ufd1-Npl4 ubiquitin-selective segregase by small ubiquitin-like modifier protein (SUMO) and ubiquitin in SUMO-targeted ubiquitin ligase-mediated genome stability functions
-
Nie M., Aslanian A., Prudden J., Heideker J., Vashisht A.A., Wohlschlegel J.A., Yates J.R., Boddy M.N. Dual recruitment of Cdc48 (p97)-Ufd1-Npl4 ubiquitin-selective segregase by small ubiquitin-like modifier protein (SUMO) and ubiquitin in SUMO-targeted ubiquitin ligase-mediated genome stability functions. J.Biol. Chem. 2012, 287:29610-29619.
-
(2012)
J.Biol. Chem.
, vol.287
, pp. 29610-29619
-
-
Nie, M.1
Aslanian, A.2
Prudden, J.3
Heideker, J.4
Vashisht, A.A.5
Wohlschlegel, J.A.6
Yates, J.R.7
Boddy, M.N.8
-
21
-
-
78650246421
-
A transcriptional activator is part of an SCF ubiquitin ligase to control degradation of its cofactors
-
Ouni I., Flick K., Kaiser P. A transcriptional activator is part of an SCF ubiquitin ligase to control degradation of its cofactors. Mol. Cell 2010, 40:954-964.
-
(2010)
Mol. Cell
, vol.40
, pp. 954-964
-
-
Ouni, I.1
Flick, K.2
Kaiser, P.3
-
22
-
-
79958695933
-
Ubiquitin and transcription: The SCF/Met4 pathway, a (protein-) complex issue
-
Ouni I., Flick K., Kaiser P. Ubiquitin and transcription: The SCF/Met4 pathway, a (protein-) complex issue. Transcription 2011, 2:135-139.
-
(2011)
Transcription
, vol.2
, pp. 135-139
-
-
Ouni, I.1
Flick, K.2
Kaiser, P.3
-
23
-
-
0021679940
-
The yeast ubiquitin gene: head-to-tail repeats encoding a polyubiquitin precursor protein
-
Ozkaynak E., Finley D., Varshavsky A. The yeast ubiquitin gene: head-to-tail repeats encoding a polyubiquitin precursor protein. Nature 1984, 312:663-666.
-
(1984)
Nature
, vol.312
, pp. 663-666
-
-
Ozkaynak, E.1
Finley, D.2
Varshavsky, A.3
-
24
-
-
21744460209
-
Ufd1 exhibits the AAA-ATPase fold with two distinct ubiquitin interaction sites
-
Park S., Isaacson R., Kim H.T., Silver P.A., Wagner G. Ufd1 exhibits the AAA-ATPase fold with two distinct ubiquitin interaction sites. Structure 2005, 13:995-1005.
-
(2005)
Structure
, vol.13
, pp. 995-1005
-
-
Park, S.1
Isaacson, R.2
Kim, H.T.3
Silver, P.A.4
Wagner, G.5
-
25
-
-
0037462954
-
N-terminal acetyltransferases and sequence requirements for N-terminal acetylation of eukaryotic proteins
-
Polevoda B., Sherman F. N-terminal acetyltransferases and sequence requirements for N-terminal acetylation of eukaryotic proteins. J.Mol. Biol. 2003, 325:595-622.
-
(2003)
J.Mol. Biol.
, vol.325
, pp. 595-622
-
-
Polevoda, B.1
Sherman, F.2
-
26
-
-
37549068963
-
Cdc48/p97 promotes reformation of the nucleus by extracting the kinase Aurora B from chromatin
-
Ramadan K., Bruderer R., Spiga F.M., Popp O., Baur T., Gotta M., Meyer H.H. Cdc48/p97 promotes reformation of the nucleus by extracting the kinase Aurora B from chromatin. Nature 2007, 450:1258-1262.
-
(2007)
Nature
, vol.450
, pp. 1258-1262
-
-
Ramadan, K.1
Bruderer, R.2
Spiga, F.M.3
Popp, O.4
Baur, T.5
Gotta, M.6
Meyer, H.H.7
-
27
-
-
80053583606
-
A genome-wide screen identifies p97 as an essential regulator of DNA damage-dependent CDT1 destruction
-
Raman M., Havens C.G., Walter J.C., Harper J.W. A genome-wide screen identifies p97 as an essential regulator of DNA damage-dependent CDT1 destruction. Mol. Cell 2011, 44:72-84.
-
(2011)
Mol. Cell
, vol.44
, pp. 72-84
-
-
Raman, M.1
Havens, C.G.2
Walter, J.C.3
Harper, J.W.4
-
28
-
-
0035977095
-
Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone
-
Rape M., Hoppe T., Gorr I., Kalocay M., Richly H., Jentsch S. Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone. Cell 2001, 107:667-677.
-
(2001)
Cell
, vol.107
, pp. 667-677
-
-
Rape, M.1
Hoppe, T.2
Gorr, I.3
Kalocay, M.4
Richly, H.5
Jentsch, S.6
-
29
-
-
0032168508
-
Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome
-
Rubin D.M., Glickman M.H., Larsen C.N., Dhruvakumar S., Finley D. Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome. EMBO J. 1998, 17:4909-4919.
-
(1998)
EMBO J.
, vol.17
, pp. 4909-4919
-
-
Rubin, D.M.1
Glickman, M.H.2
Larsen, C.N.3
Dhruvakumar, S.4
Finley, D.5
-
30
-
-
0035979738
-
Regulation of transcriptional activation domain function by ubiquitin
-
Salghetti S.E., Caudy A.A., Chenoweth J.G., Tansey W.P. Regulation of transcriptional activation domain function by ubiquitin. Science 2001, 293:1651-1653.
-
(2001)
Science
, vol.293
, pp. 1651-1653
-
-
Salghetti, S.E.1
Caudy, A.A.2
Chenoweth, J.G.3
Tansey, W.P.4
-
31
-
-
49249130739
-
UBX domain proteins: major regulators of the AAA ATPase Cdc48/p97
-
Schuberth C., Buchberger A. UBX domain proteins: major regulators of the AAA ATPase Cdc48/p97. Cell. Mol. Life Sci. 2008, 65:2360-2371.
-
(2008)
Cell. Mol. Life Sci.
, vol.65
, pp. 2360-2371
-
-
Schuberth, C.1
Buchberger, A.2
-
32
-
-
82455210962
-
Ablation of Smurf2 reveals an inhibition in TGF-beta signalling through multiple mono-ubiquitination of Smad3
-
Tang L.Y., Yamashita M., Coussens N.P., Tang Y., Wang X., Li C., Deng C.X., Cheng S.Y., Zhang Y.E. Ablation of Smurf2 reveals an inhibition in TGF-beta signalling through multiple mono-ubiquitination of Smad3. EMBO J. 2011, 30:4777-4789.
-
(2011)
EMBO J.
, vol.30
, pp. 4777-4789
-
-
Tang, L.Y.1
Yamashita, M.2
Coussens, N.P.3
Tang, Y.4
Wang, X.5
Li, C.6
Deng, C.X.7
Cheng, S.Y.8
Zhang, Y.E.9
-
33
-
-
33749188883
-
FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP
-
van der Horst A., de Vries-Smits A.M., Brenkman A.B., van Triest M.H., van den Broek N., Colland F., Maurice M.M., Burgering B.M. FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP. Nat. Cell Biol. 2006, 8:1064-1073.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 1064-1073
-
-
van der Horst, A.1
de Vries-Smits, A.M.2
Brenkman, A.B.3
van Triest, M.H.4
van den Broek, N.5
Colland, F.6
Maurice, M.M.7
Burgering, B.M.8
-
34
-
-
78650733298
-
Cdc48/p97 mediates UV-dependent turnover of RNA Pol II
-
Verma R., Oania R., Fang R., Smith G.T., Deshaies R.J. Cdc48/p97 mediates UV-dependent turnover of RNA Pol II. Mol. Cell 2011, 41:82-92.
-
(2011)
Mol. Cell
, vol.41
, pp. 82-92
-
-
Verma, R.1
Oania, R.2
Fang, R.3
Smith, G.T.4
Deshaies, R.J.5
-
36
-
-
52949125234
-
Roles of mono-ubiquitinated Smad4 in the formation of Smad transcriptional complexes
-
Wang B., Suzuki H., Kato M. Roles of mono-ubiquitinated Smad4 in the formation of Smad transcriptional complexes. Biochem. Biophys. Res. Commun. 2008, 376:288-292.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.376
, pp. 288-292
-
-
Wang, B.1
Suzuki, H.2
Kato, M.3
-
37
-
-
73349115264
-
A ubiquitin-selective AAA-ATPase mediates transcriptional switching by remodelling a repressor-promoter DNA complex
-
Wilcox A.J., Laney J.D. A ubiquitin-selective AAA-ATPase mediates transcriptional switching by remodelling a repressor-promoter DNA complex. Nat. Cell Biol. 2009, 11:1481-1486.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 1481-1486
-
-
Wilcox, A.J.1
Laney, J.D.2
-
38
-
-
84863870650
-
Regulation of gene expression by the ubiquitin-proteasome system
-
Yao T., Ndoja A. Regulation of gene expression by the ubiquitin-proteasome system. Semin. Cell Dev. Biol. 2012, 23:523-529.
-
(2012)
Semin. Cell Dev. Biol.
, vol.23
, pp. 523-529
-
-
Yao, T.1
Ndoja, A.2
-
39
-
-
33749236210
-
Diverse functions with a common regulator: ubiquitin takes command of an AAA ATPase
-
Ye Y. Diverse functions with a common regulator: ubiquitin takes command of an AAA ATPase. J.Struct. Biol. 2006, 156:29-40.
-
(2006)
J.Struct. Biol.
, vol.156
, pp. 29-40
-
-
Ye, Y.1
-
40
-
-
0038487228
-
Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains
-
Ye Y., Meyer H.H., Rapoport T.A. Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains. J.Cell Biol. 2003, 162:71-84.
-
(2003)
J.Cell Biol.
, vol.162
, pp. 71-84
-
-
Ye, Y.1
Meyer, H.H.2
Rapoport, T.A.3
|