Difference in LDL receptor feedback regulation in macrophages and vascular smooth muscle cells: Foam cell transformation under inflammatory stress

Inflammation

Volumn 37, Issue 2, 2014, Pages 555-565

  Ye, Qiang ^a,b   Lei, Han ^b   Fan, Zhongcai ^a   Zheng, Wenwu ^a   Zheng, Shuzhan ^a  

^a SOUTHWEST MEDICAL UNIVERSITY   (China)

^b CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

foam cells; lipopolysaccharide; low density lipoprotein receptor; macrophages; SREBP cleavage activating protein; sterol regulatory element binding protein2; vascular smooth muscle cells

Indexed keywords

CHOLESTEROL; CHOLESTEROL ESTER; FAT DROPLET; HEPARIN; LIPOPOLYSACCHARIDE; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; STEROL REGULATORY ELEMENT BINDING PROTEIN CLEAVAGE ACTIVATING PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL LEVEL; CELL TRANSFORMATION; CHOLESTEROL BLOOD LEVEL; CONCENTRATION (PARAMETERS); CONFOCAL MICROSCOPY; CONTROLLED STUDY; CULTURE MEDIUM; ENZYMATIC ASSAY; FEEDBACK SYSTEM; FOAM CELL; GOLGI STAIN; HUMAN; HUMAN CELL; IC 50; INFLAMMATION; MACROPHAGE; NEGATIVE FEEDBACK; PROTEIN EXPRESSION; PROTEIN TRANSPORT; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; STRESS; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

CELL LINE; CHOLESTEROL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEEDBACK, PHYSIOLOGICAL; FOAM CELLS; HUMANS; INFLAMMATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPOPOLYSACCHARIDES; LIPOPROTEINS, LDL; MEMBRANE PROTEINS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PROTEIN TRANSPORT; RECEPTORS, LDL; RNA, MESSENGER; STEROL REGULATORY ELEMENT BINDING PROTEIN 2;

EID: 84896389041     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-013-9769-x     Document Type: Article

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