Synthesis and preliminary evaluation of a 2-Oxoquinoline carboxylic acid derivative for PET imaging the cannabinoid type 2 receptor

Pharmaceuticals

Volumn 7, Issue 3, 2014, Pages 339-352

  Mu, Linjing ^a   Slavik, Roger ^b   Müller, Adrienne ^b   Popaj, Kasim ^a   Čermak, Stjepko ^b   Weber, Markus ^c   Schibli, Roger ^a,b   Krämer, Stefanie D ^b   Ametamey, Simon M ^b  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b ETH ZURICH   (Switzerland)

^c Neuromuscular Diseases Centre   (Switzerland)

Author keywords

Autoradiography; Cannabinoid receptor type 2 ligand; CB2 receptor; Neurodegeneration; Radiolabeling; Small animal PET

Indexed keywords

8 BUTOXY N (2 FLUORO 2 PHENYLETHYL) 7 HYDROXY 2 OXO 1,2 DIHYDROQUINOLINE 3 CARBOXAMIDE C 11; CANNABINOID 2 RECEPTOR; KP 26; QUINOLINE DERIVATIVE; TRACER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; BRAIN; CONTROLLED STUDY; DRUG STABILITY; DRUG SYNTHESIS; FEMALE; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; MALE; MOUSE; NONHUMAN; PET-CT SCANNER; POSITRON EMISSION TOMOGRAPHY; RADIOCHEMISTRY; RAT; SPLEEN; TISSUE DISTRIBUTION; WISTAR RAT;

EID: 84896379446     PISSN: None     EISSN: 14248247     Source Type: Journal    
DOI: 10.3390/ph7030339     Document Type: Article

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