Linking microcircuit dysfunction to cognitive impairment: Effects of disinhibition associated with schizophrenia in a cortical working memory model

Cerebral Cortex

Volumn 24, Issue 4, 2014, Pages 859-872

  Murray, John D ^a,b   Anticevic, Alan ^b,c   Gancsos, Mark ^b   Ichinose, Megan ^b   Corlett, Philip R ^b,c   Krystal, John H ^b,c,d,e   Wang, Xiao Jing ^b,f  

^a Yale University   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Yale University School of Medicine   (United States)

^d YALE NEW HAVEN HOSPITAL   (United States)

^e VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

^f NEW YORK UNIVERSITY   (United States)

Author keywords

disinhibition; NMDAR hypofunction; prefrontal cortex; schizophrenia; working memory

Indexed keywords

KETAMINE;

ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; CORTICAL DISINHIBITION; DISTRACTIBILITY; HUMAN; HUMAN EXPERIMENT; INTERNEURON; MODEL; NORMAL HUMAN; PREDICTION; PREFRONTAL CORTEX; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; SCHIZOPHRENIA; SPATIAL MEMORY; STIMULUS RESPONSE; SYNAPTIC TRANSMISSION; TASK PERFORMANCE; WORKING MEMORY;

DISINHIBITION; NMDAR HYPOFUNCTION; PREFRONTAL CORTEX; SCHIZOPHRENIA; WORKING MEMORY;

CEREBRAL CORTEX; COGNITION DISORDERS; COMPUTER SIMULATION; HUMANS; MEMORY DISORDERS; MEMORY, SHORT-TERM; MODELS, NEUROLOGICAL; NERVE NET; NEURONS; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 84896359684     PISSN: 10473211     EISSN: 14602199     Source Type: Journal    
DOI: 10.1093/cercor/bhs370     Document Type: Article

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