Overexpression of c-Met and CD44v6 receptors contributes to autocrine TGF-β1 signaling in interstitial lung disease

Journal of Biological Chemistry

Volumn 289, Issue 11, 2014, Pages 7856-7872

  Ghatak, Shibnath ^a   Bogatkevich, Galina S ^a   Atnelishvilis, Ilia ^a   Akters, Tanjina ^a   Feghali Bostwick, Carol ^a   Hoffmans, Stanley ^a   Fresco, Victor M ^a   Fuchs, John C ^a   Visconti, Richard P ^a   Markwald, Roger R ^a   Padhye, Subhas B ^b   Silver, Richard M ^a   Hascall, Vincent C ^c   Misra, Suniti ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b UNIVERSITY OF PUNE   (India)

^c LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; CELL CULTURE; CELL PROLIFERATION; COLLAGEN; FIBROBLASTS; HYALURONIC ACID; MAMMALS; PATIENT TREATMENT; PEPTIDES;

CELLULAR FUNCTION; HEPATOCYTE GROWTH FACTOR; INTERSTITIAL LUNG DISEASE; LUNG FIBROBLASTS; OVER-EXPRESSION; PROTEIN EXPRESSIONS; SMOOTH MUSCLE CELLS; WESTERN-BLOT ANALYSIS;

SIGNALING;

BLEOMYCIN; CD44V6 ANTIGEN; COLLAGEN TYPE 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; SCATTER FACTOR RECEPTOR; SMOOTH MUSCLE ACTIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOCRINE EFFECT; CELL PROLIFERATION; CELL SUBPOPULATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; FIBROBLAST; GENE EXPRESSION REGULATION; GENE LOCATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; INTERSTITIAL LUNG DISEASE; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TISSUE SECTION;

CD44; COLLAGEN; FIBROBLAST; PULMONARY FIBROSIS; TRANSFORMING GROWTH FACTOR BETA (TGFBETA);

ANIMALS; ANTIGENS, CD44; AUTOCRINE COMMUNICATION; CELL NUCLEUS; CELL PROLIFERATION; CELLS, CULTURED; CULTURE MEDIA; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROBLASTS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HEPATOCYTE GROWTH FACTOR; HUMANS; LUNG; LUNG DISEASES, INTERSTITIAL; MALE; MICE; MICE, INBRED C57BL; PROTO-ONCOGENE PROTEINS C-MET; PULMONARY FIBROSIS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84896291379     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.505065     Document Type: Article

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