-
1
-
-
0025210095
-
Fibroblast-matrix interactions and their role in the pathogenesis of fibrosis
-
Mauch C, Kreig T. Fibroblast-matrix interactions and their role in the pathogenesis of fibrosis. Rheum Dis Clin North Am. 1990; 16:93-107.
-
(1990)
Rheum Dis Clin North Am
, vol.16
, pp. 93-107
-
-
Mauch, C.1
Kreig, T.2
-
2
-
-
0024887547
-
Immunologic aspects of scleroderma
-
Korn JH. Immunologic aspects of scleroderma. Curr Opin Rheumatol. 1989; 1:479-484.
-
(1989)
Curr Opin Rheumatol
, vol.1
, pp. 479-484
-
-
Korn, J.H.1
-
3
-
-
0025222517
-
The transforming growth factor β family
-
Massagué J. The transforming growth factor β family. Annu Rev Cell Biol. 1990; 6:597-641.
-
(1990)
Annu Rev Cell Biol
, vol.6
, pp. 597-641
-
-
Massagué, J.1
-
4
-
-
0024323330
-
A strategy for determining the pathogenesis of systemic sclerosis Is transforming growth factor β the answer?
-
LeRoy EC, Smith EA, Kahaleh MB, Trojanowska M, Silver RM. A strategy for determining the pathogenesis of systemic sclerosis. Is transforming growth factor β the answer? Arthritis Rheum. 1989; 32:817-825.
-
(1989)
Arthritis Rheum
, vol.32
, pp. 817-825
-
-
Le Roy, E.C.1
Smith, E.A.2
Kahaleh, M.B.3
Trojanowska, M.4
Silver, R.M.5
-
5
-
-
0016302998
-
Increased collagen synthesis by scleroderma skin fibroblasts in vitro: A possible defect in the regulation or activation of the scleroderma fibroblast
-
LeRoy EC. Increased collagen synthesis by scleroderma skin fibroblasts in vitro: A possible defect in the regulation or activation of the scleroderma fibroblast. J Clin Invest. 1974; 54:880-889.
-
(1974)
J Clin Invest
, vol.54
, pp. 880-889
-
-
Le Roy, E.C.1
-
6
-
-
0022493764
-
Co-ordinate increase in the expression of type I and type III collagen genes in progressive systemic sclerosis fibroblasts
-
Jimenez SA, Feldman G, Bashey RI, Bienkowski R, Rosenbloom J. Co-ordinate increase in the expression of type I and type III collagen genes in progressive systemic sclerosis fibroblasts. Biochem J. 1986; 237:837-843.
-
(1986)
Biochem J
, vol.237
, pp. 837-843
-
-
Jimenez, S.A.1
Feldman, G.2
Bashey, R.I.3
Bienkowski, R.4
Rosenbloom, J.5
-
7
-
-
0038004796
-
Expression and regulation of intracellular SMAD signaling in scleroderma skin fibroblasts
-
Mori Y, Chen SJ, Varga J. Expression and regulation of intracellular SMAD signaling in scleroderma skin fibroblasts. Arthritis Rheum. 2003; 48:1964-1978.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 1964-1978
-
-
Mori, Y.1
Chen, S.J.2
Varga, J.3
-
8
-
-
2442640271
-
Phosphatidylinositol 3-kinase is involved in α2(I) collagen gene expression in normal and scleroderma fibroblasts
-
Asano Y, Ihn H, Yamane K, Jinnin M, Mimura Y, Tamaki K. Phosphatidylinositol 3-kinase is involved in α2(I) collagen gene expression in normal and scleroderma fibroblasts. J Immunol. 2004; 172:7123-7135.
-
(2004)
J Immunol
, vol.172
, pp. 7123-7135
-
-
Asano, Y.1
Ihn, H.2
Yamane, K.3
Jinnin, M.4
Mimura, Y.5
Tamaki, K.6
-
9
-
-
85047692249
-
Impaired Smad7-Smurf-mediated negative regulation of TGF-β signaling in scleroderma fibroblasts
-
Asano Y, Ihn H, Yamane K, Kubo M, Tamaki K. Impaired Smad7-Smurf-mediated negative regulation of TGF-β signaling in scleroderma fibroblasts. J Clin Invest. 2004; 113:253-264.
-
(2004)
J Clin Invest
, vol.113
, pp. 253-264
-
-
Asano, Y.1
Ihn, H.2
Yamane, K.3
Kubo, M.4
Tamaki, K.5
-
10
-
-
0035089825
-
Blockade of endogenous transforming growth factor β signaling prevents up-regulated collagen synthesis in scleroderma fibroblasts: Association with increased expression of transforming growth factor b receptors
-
Ihn H, Yamane K, Kubo M, Tamaki K. Blockade of endogenous transforming growth factor β signaling prevents up-regulated collagen synthesis in scleroderma fibroblasts: Association with increased expression of transforming growth factor b receptors. Arthritis Rheum. 2001; 44:474-480.
-
(2001)
Arthritis Rheum
, vol.44
, pp. 474-480
-
-
Ihn, H.1
Yamane, K.2
Kubo, M.3
Tamaki, K.4
-
11
-
-
0026666859
-
Direct demonstration of transcriptional activation of collagen gene expression in systemic sclerosis fibroblasts: insensitivity to TGF-β1 stimulation
-
Kikuchi K, Hartl CW, Smith EA, LeRoy EC, Trojanowska M. Direct demonstration of transcriptional activation of collagen gene expression in systemic sclerosis fibroblasts: insensitivity to TGF-β1 stimulation. Biochem Biophys Res Commun. 1992; 187:45-50.
-
(1992)
Biochem Biophys Res Commun
, vol.187
, pp. 45-50
-
-
Kikuchi, K.1
Hartl, C.W.2
Smith, E.A.3
Le Roy, E.C.4
Trojanowska, M.5
-
12
-
-
33645949405
-
Potential regulatory elements of the constitutive upregulated α2(I) collagen gene in scleroderma dermal fibroblasts
-
Jinnin M, Ihn H, Mimura Y, Asano Y, Tamaki K. Potential regulatory elements of the constitutive upregulated α2(I) collagen gene in scleroderma dermal fibroblasts. Biochem Biophys Res Commun. 2006; 343:904-909.
-
(2006)
Biochem Biophys Res Commun
, vol.343
, pp. 904-909
-
-
Jinnin, M.1
Ihn, H.2
Mimura, Y.3
Asano, Y.4
Tamaki, K.5
-
13
-
-
0025734655
-
Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-Met
-
Naldini L, Vigna E, Narsimhan RP, Gaudino G, Zarnegar R, Michalopoulos GK, Comoglio PM. Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-Met. Oncogene. 1991; 6:501-504.
-
(1991)
Oncogene
, vol.6
, pp. 501-504
-
-
Naldini, L.1
Vigna, E.2
Narsimhan, R.P.3
Gaudino, G.4
Zarnegar, R.5
Michalopoulos, G.K.6
Comoglio, P.M.7
-
14
-
-
21344468813
-
Matrix metalloproteinase-1 up-regulation by hepatocyte growth factor in human dermal fibroblasts via ERK signaling pathway involves Ets1 and Fli1
-
Jinnin M, Ihn H, Mimura Y, Asano Y, Yamane K, Tamaki K. Matrix metalloproteinase-1 up-regulation by hepatocyte growth factor in human dermal fibroblasts via ERK signaling pathway involves Ets1 and Fli1. Nucleic Acids Res. 2005; 33:3540-3549.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 3540-3549
-
-
Jinnin, M.1
Ihn, H.2
Mimura, Y.3
Asano, Y.4
Yamane, K.5
Tamaki, K.6
-
15
-
-
35348874419
-
Downregulation of collagen and connective tissue growth factor expression with hepatocyte growth factor in lung fibroblasts from white scleroderma patients via two signaling pathways
-
Bogatkevich GS, Ludwicka-Bradley A, Highland KB, Hant F, Nietert PJ, Singleton CB, Silver RM. Downregulation of collagen and connective tissue growth factor expression with hepatocyte growth factor in lung fibroblasts from white scleroderma patients via two signaling pathways. Arthritis Rheum. 2007; 56:3468-3477.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 3468-3477
-
-
Bogatkevich, G.S.1
Ludwicka-Bradley, A.2
Highland, K.B.3
Hant, F.4
Nietert, P.J.5
Singleton, C.B.6
Silver, R.M.7
-
16
-
-
0036731985
-
Expression of hepatocyte growth factor and its receptor (c-met) in skin fibroblasts from patients with systemic sclerosis
-
Kawaguchi Y, Harigai M, Hara M, Fukasawa C, Takagi K, Tanaka M, Tanaka E, Nishimagi E, Kamatani N. Expression of hepatocyte growth factor and its receptor (c-met) in skin fibroblasts from patients with systemic sclerosis. J Rheumatol. 2002; 29:1877-1883.
-
(2002)
J Rheumatol
, vol.29
, pp. 1877-1883
-
-
Kawaguchi, Y.1
Harigai, M.2
Hara, M.3
Fukasawa, C.4
Takagi, K.5
Tanaka, M.6
Tanaka, E.7
Nishimagi, E.8
Kamatani, N.9
-
17
-
-
0030870170
-
Oncostatin M stimulates transcription of the human α2(I) collagen gene via the Sp1/Sp3-binding site
-
Ihn H, Le Roy EC, Trojanowska M. Oncostatin M stimulates transcription of the human α2(I) collagen gene via the Sp1/Sp3-binding site. J Biol Chem. 1997; 272:24666-24672.
-
(1997)
J Biol Chem
, vol.272
, pp. 24666-24672
-
-
Ihn, H.1
Le Roy, E.C.2
Trojanowska, M.3
-
18
-
-
77949821778
-
Basic fibroblast growth factor stimulates the proliferation of human dermal fibroblasts via the ERK1/2 and JNK pathways
-
Makino T, Jinnin M, Muchemwa FC, Fukushima S, Kogushi-Nishi H, Moriya C, Igata T, Fujisawa A, Johno T, Ihn H. Basic fibroblast growth factor stimulates the proliferation of human dermal fibroblasts via the ERK1/2 and JNK pathways. Br J Dermatol. 2010; 162:717-723.
-
(2010)
Br J Dermatol
, vol.162
, pp. 717-723
-
-
Makino, T.1
Jinnin, M.2
Muchemwa, F.C.3
Fukushima, S.4
Kogushi-Nishi, H.5
Moriya, C.6
Igata, T.7
Fujisawa, A.8
Johno, T.9
Ihn, H.10
-
19
-
-
77249170182
-
Up-regulated type I collagen expression by the inhibition of Rac1 signaling pathway in human dermal fibroblasts
-
Igata T, Jinnin M, Makino T, Moriya C, Muchemwa FC, Ishihara T, Ihn H. Up-regulated type I collagen expression by the inhibition of Rac1 signaling pathway in human dermal fibroblasts. Biochem Biophys Res Commun 2010; 393:101-105.
-
(2010)
Biochem Biophys Res Commun
, vol.393
, pp. 101-105
-
-
Igata, T.1
Jinnin, M.2
Makino, T.3
Moriya, C.4
Muchemwa, F.C.5
Ishihara, T.6
Ihn, H.7
-
20
-
-
0037016689
-
c-myc is a downstream target of the Smad pathway
-
Yagi K, Furuhashi M, Aoki H, Goto D, Kuwano H, Sugamura K, Miyazono K, Kato M. c-myc is a downstream target of the Smad pathway. J Biol Chem. 2002; 277:854-861.
-
(2002)
J Biol Chem
, vol.277
, pp. 854-861
-
-
Yagi, K.1
Furuhashi, M.2
Aoki, H.3
Goto, D.4
Kuwano, H.5
Sugamura, K.6
Miyazono, K.7
Kato, M.8
-
21
-
-
33746141265
-
Involvement of alphavbeta5 integrin in the establishment of autocrine TGF-β signaling in dermal fibroblasts derived from localized scleroderma
-
Asano Y, Ihn H, Jinnin M, Mimura Y, Tamaki K. Involvement of alphavbeta5 integrin in the establishment of autocrine TGF-β signaling in dermal fibroblasts derived from localized scleroderma. J Invest Dermatol. 2006; 126:1761-1769.
-
(2006)
J Invest Dermatol
, vol.126
, pp. 1761-1769
-
-
Asano, Y.1
Ihn, H.2
Jinnin, M.3
Mimura, Y.4
Tamaki, K.5
-
22
-
-
0032101178
-
Direct binding of Smad3 and Smad4 to critical TGF-β-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
-
Dennler S, Itoh S, Vivien D, ten Dijke P, Huet S, Gauthier JM. Direct binding of Smad3 and Smad4 to critical TGF-β-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO J. 1998; 17:3091-3100.
-
(1998)
EMBO J
, vol.17
, pp. 3091-3100
-
-
Dennler, S.1
Itoh, S.2
Vivien, D.3
ten Dijke, P.4
Huet, S.5
Gauthier, J.M.6
-
23
-
-
0032921867
-
-
Chen SJ, Yuan W, Mori Y, Levenson A, Trojanowska M, Varga J. Stimulation of type I collagen transcription in human skin fibroblasts by TGF-β: Involvement of Smad J Invest Dermatol. 1999; 112:49-57.
-
(1999)
Stimulation of type I collagen transcription in human skin fibroblasts by TGF-β: Involvement of Smad J Invest Dermatol
, vol.112
, pp. 49-57
-
-
Chen, S.J.1
Yuan, W.2
Mori, Y.3
Levenson, A.4
Trojanowska, M.5
Varga, J.6
-
24
-
-
31544442502
-
Constitutively phosphorylated Smad3 interacts with Sp1 and p300 in scleroderma fibroblasts
-
Ihn H, Yamane K, Asano Y, Jinnin M, Tamaki K. Constitutively phosphorylated Smad3 interacts with Sp1 and p300 in scleroderma fibroblasts. Rheumatology. 2006; 45:157-165.
-
(2006)
Rheumatology
, vol.45
, pp. 157-165
-
-
Ihn, H.1
Yamane, K.2
Asano, Y.3
Jinnin, M.4
Tamaki, K.5
-
25
-
-
0034970031
-
A randomized, controlled trial of methotrexate versus placebo in early diffuse scleroderma
-
Pope JE, Bellamy N, Seibold JR, Baron M, Ellman M, Carette S, Smith CD, Chalmers IM, Hong P, O'Hanlon D, Kaminska E, Markland J, Sibley J, Catoggio L, Furst DE. A randomized, controlled trial of methotrexate versus placebo in early diffuse scleroderma. Arthritis Rheum. 2001; 44:1351-1358.
-
(2001)
Arthritis Rheum
, vol.44
, pp. 1351-1358
-
-
Pope, J.E.1
Bellamy, N.2
Seibold, J.R.3
Baron, M.4
Ellman, M.5
Carette, S.6
Smith, C.D.7
Chalmers, I.M.8
Hong, P.9
O'Hanlon, D.10
Kaminska, E.11
Markland, J.12
Sibley, J.13
Catoggio, L.14
Furst, D.E.15
-
26
-
-
0042573935
-
Effects of oral cyclophosphamide and prednisolone therapy on the endothelial functions and clinical findings in patients with early diffuse systemic sclerosis
-
Apras S, Ertenli I, Ozbalkan Z, Kiraz S, Ozturk MA, Haznedaroglu IC, Cobankara V, Pay S, Calguneri M. Effects of oral cyclophosphamide and prednisolone therapy on the endothelial functions and clinical findings in patients with early diffuse systemic sclerosis. Arthritis Rheum. 2003; 48:2256-2261.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 2256-2261
-
-
Apras, S.1
Ertenli, I.2
Ozbalkan, Z.3
Kiraz, S.4
Ozturk, M.A.5
Haznedaroglu, I.C.6
Cobankara, V.7
Pay, S.8
Calguneri, M.9
-
27
-
-
3242796559
-
Systemic sclerosis-scleroderma
-
Haustein UF. Systemic sclerosis-scleroderma. Dermatol Online J. 2002; 8:3.
-
(2002)
Dermatol Online J
, vol.8
, pp. 3
-
-
Haustein, U.F.1
|