메뉴 건너뛰기




Volumn 28, Issue 2, 2014, Pages 221-232

Impact of mild thyroid hormone deficiency in pregnancy on cognitive function in children: Lessons from the Generation R Study

Author keywords

behaviour; children; cognition; executive function; hypothyroxinaemia; iodine; pregnancy; thyroid

Indexed keywords

THYROID HORMONE;

EID: 84896089443     PISSN: 1521690X     EISSN: 15321908     Source Type: Journal    
DOI: 10.1016/j.beem.2013.04.008     Document Type: Review
Times cited : (40)

References (68)
  • 3
    • 0033584418 scopus 로고    scopus 로고
    • Maternal hypothyroidism and fetal development
    • R.D. Utiger Maternal hypothyroidism and fetal development The New England Journal of Medicine 341 1999 601 602
    • (1999) The New England Journal of Medicine , vol.341 , pp. 601-602
    • Utiger, R.D.1
  • 6
    • 45549103899 scopus 로고    scopus 로고
    • Neurodevelopmental and neurophysiological actions of thyroid hormone
    • G.R. Williams Neurodevelopmental and neurophysiological actions of thyroid hormone Journal of Neuroendocrinology 20 2008 784 794
    • (2008) Journal of Neuroendocrinology , vol.20 , pp. 784-794
    • Williams, G.R.1
  • 7
    • 33846093170 scopus 로고    scopus 로고
    • Sodium/iodide symporter (NIS) gene expression is the limiting step for the onset of thyroid function in the human fetus
    • G. Szinnai, L. Lacroix, and A. Carre et al. Sodium/iodide symporter (NIS) gene expression is the limiting step for the onset of thyroid function in the human fetus The Journal of Clinical Endocrinology and Metabolism 92 2007 70 76
    • (2007) The Journal of Clinical Endocrinology and Metabolism , vol.92 , pp. 70-76
    • Szinnai, G.1    Lacroix, L.2    Carre, A.3
  • 8
    • 84864509690 scopus 로고    scopus 로고
    • Developmental thyroid hormone disruption: Prevalence, environmental contaminants and neurodevelopmental consequences
    • M.E. Gilbert, J. Rovet, and Z. Chen et al. Developmental thyroid hormone disruption: prevalence, environmental contaminants and neurodevelopmental consequences Neurotoxicology 33 2012 842 852
    • (2012) Neurotoxicology , vol.33 , pp. 842-852
    • Gilbert, M.E.1    Rovet, J.2    Chen, Z.3
  • 10
    • 0033584469 scopus 로고    scopus 로고
    • Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child
    • J.E. Haddow, G.E. Palomaki, and W.C. Allan et al. Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child The New England Journal of Medicine 341 1999 549 555
    • (1999) The New England Journal of Medicine , vol.341 , pp. 549-555
    • Haddow, J.E.1    Palomaki, G.E.2    Allan, W.C.3
  • 11
    • 0033071741 scopus 로고    scopus 로고
    • Low maternal free thyroxine concentrations during early pregnancy are associated with impaired psychomotor development in infancy
    • V.J. Pop, J.L. Kuijpens, and A.L. van Baar et al. Low maternal free thyroxine concentrations during early pregnancy are associated with impaired psychomotor development in infancy Clinical Endocrinology 50 1999 149 155
    • (1999) Clinical Endocrinology , vol.50 , pp. 149-155
    • Pop, V.J.1    Kuijpens, J.L.2    Van Baar, A.L.3
  • 12
    • 3242666436 scopus 로고    scopus 로고
    • A moderate and transient deficiency of maternal thyroid function at the beginning of fetal neocorticogenesis alters neuronal migration
    • E. Auso, R. Lavado-Autric, and E. Cuevas et al. A moderate and transient deficiency of maternal thyroid function at the beginning of fetal neocorticogenesis alters neuronal migration Endocrinology 145 2004 4037 4047
    • (2004) Endocrinology , vol.145 , pp. 4037-4047
    • Auso, E.1    Lavado-Autric, R.2    Cuevas, E.3
  • 13
    • 77954143694 scopus 로고    scopus 로고
    • A volumetric analysis of the brain and hippocampus of rats rendered perinatal hypothyroid
    • M. Hasegawa, I. Kida, and H. Wada A volumetric analysis of the brain and hippocampus of rats rendered perinatal hypothyroid Neuroscience Letters 479 2010 240 244
    • (2010) Neuroscience Letters , vol.479 , pp. 240-244
    • Hasegawa, M.1    Kida, I.2    Wada, H.3
  • 15
    • 33947628682 scopus 로고    scopus 로고
    • Marked recovery of functional metabolic activity and laminar volumes in the rat hippocampus and dentate gyrus following postnatal hypothyroid growth retardation: A quantitative cytochrome oxidase study
    • A. Farahvar, N.H. Darwish, and S. Sladek et al. Marked recovery of functional metabolic activity and laminar volumes in the rat hippocampus and dentate gyrus following postnatal hypothyroid growth retardation: a quantitative cytochrome oxidase study Experimental Neurology 204 2007 556 568
    • (2007) Experimental Neurology , vol.204 , pp. 556-568
    • Farahvar, A.1    Darwish, N.H.2    Sladek, S.3
  • 16
    • 34548567290 scopus 로고    scopus 로고
    • Autism: Transient in utero hypothyroxinemia related to maternal flavonoid ingestion during pregnancy and to other environmental antithyroid agents
    • G.C. Roman Autism: transient in utero hypothyroxinemia related to maternal flavonoid ingestion during pregnancy and to other environmental antithyroid agents Journal of the Neurological Sciences 262 2007 15 26
    • (2007) Journal of the Neurological Sciences , vol.262 , pp. 15-26
    • Roman, G.C.1
  • 18
    • 3042577535 scopus 로고    scopus 로고
    • The regulation of thyroid function during normal pregnancy: Importance of the iodine nutrition status
    • D. Glinoer The regulation of thyroid function during normal pregnancy: importance of the iodine nutrition status Best Practice and Research. Clinical Endocrinology and Metabolism 18 2004 133 152
    • (2004) Best Practice and Research. Clinical Endocrinology and Metabolism , vol.18 , pp. 133-152
    • Glinoer, D.1
  • 19
    • 0015175258 scopus 로고
    • Thyroid function in human pregnancy. 8. Retardation of progeny aged 7 years; Relationships to maternal age and maternal thyroid function
    • E.B. Man, W.S. Jones, and R.H. Holden et al. Thyroid function in human pregnancy. 8. Retardation of progeny aged 7 years; relationships to maternal age and maternal thyroid function American Journal of Obstetrics and Gynecology 111 1971 905 916
    • (1971) American Journal of Obstetrics and Gynecology , vol.111 , pp. 905-916
    • Man, E.B.1    Jones, W.S.2    Holden, R.H.3
  • 20
    • 0014972407 scopus 로고
    • Thyroid function in human pregnancy. VII. Development and retardation of 4-year-old progeny of euthyroid and of hypothyroxinemic women
    • E.B. Man, R.H. Holden, and W.S. Jones Thyroid function in human pregnancy. VII. Development and retardation of 4-year-old progeny of euthyroid and of hypothyroxinemic women American Journal of Obstetrics and Gynecology 109 1971 12 19
    • (1971) American Journal of Obstetrics and Gynecology , vol.109 , pp. 12-19
    • Man, E.B.1    Holden, R.H.2    Jones, W.S.3
  • 21
    • 0015353158 scopus 로고
    • Thyroid function in pregnancy and infancy. Maternal hypothyroxinemia and retardation of progeny
    • E.B. Man Thyroid function in pregnancy and infancy. Maternal hypothyroxinemia and retardation of progeny CRC Critical Reviews in Clinical Laboratory Sciences 3 1972 203 225
    • (1972) CRC Critical Reviews in Clinical Laboratory Sciences , vol.3 , pp. 203-225
    • Man, E.B.1
  • 22
    • 80053181984 scopus 로고    scopus 로고
    • Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and postpartum
    • A. Stagnaro-Green, M. Abalovich, and E. Alexander et al. Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and postpartum Thyroid 21 2011 1081 1125
    • (2011) Thyroid , vol.21 , pp. 1081-1125
    • Stagnaro-Green, A.1    Abalovich, M.2    Alexander, E.3
  • 23
    • 10344265942 scopus 로고    scopus 로고
    • Attention deficit and hyperactivity disorders in the offspring of mothers exposed to mild-moderate iodine deficiency: A possible novel iodine deficiency disorder in developed countries
    • F. Vermiglio, V.P. Lo Presti, and M. Moleti et al. Attention deficit and hyperactivity disorders in the offspring of mothers exposed to mild-moderate iodine deficiency: a possible novel iodine deficiency disorder in developed countries Journal of Clinical Endocrinology and Metabolism 89 2004 6054 6060
    • (2004) Journal of Clinical Endocrinology and Metabolism , vol.89 , pp. 6054-6060
    • Vermiglio, F.1    Lo Presti, V.P.2    Moleti, M.3
  • 24
    • 0042827493 scopus 로고    scopus 로고
    • Maternal hypothyroxinaemia during early pregnancy and subsequent child development: A 3-year follow-up study
    • V.J. Pop, E.P. Brouwers, and H.L. Vader et al. Maternal hypothyroxinaemia during early pregnancy and subsequent child development: a 3-year follow-up study Clinical Endocrinology 59 2003 282 288
    • (2003) Clinical Endocrinology , vol.59 , pp. 282-288
    • Pop, V.J.1    Brouwers, E.P.2    Vader, H.L.3
  • 25
    • 79961226767 scopus 로고    scopus 로고
    • Iodine deficiency in industrialized countries
    • M.B. Zimmermann Iodine deficiency in industrialized countries Clinical Endocrinology 75 2011 287 288
    • (2011) Clinical Endocrinology , vol.75 , pp. 287-288
    • Zimmermann, M.B.1
  • 27
    • 62349088002 scopus 로고    scopus 로고
    • Perinatal outcome of children born to mothers with thyroid dysfunction or antibodies: A prospective population-based cohort study
    • T. Mannisto, M. Vaarasmaki, and A. Pouta et al. Perinatal outcome of children born to mothers with thyroid dysfunction or antibodies: a prospective population-based cohort study Journal of Clinical Endocrinology and Metabolism 94 2009 772 779
    • (2009) Journal of Clinical Endocrinology and Metabolism , vol.94 , pp. 772-779
    • Mannisto, T.1    Vaarasmaki, M.2    Pouta, A.3
  • 29
    • 84867897980 scopus 로고    scopus 로고
    • The Generation R Study: A review of design, findings to date, and a study of the 5-HTTLPR by environmental interaction from fetal life onward
    • e7-1135 e7
    • H. Tiemeier, F.P. Velders, and E. Szekely et al. The Generation R Study: a review of design, findings to date, and a study of the 5-HTTLPR by environmental interaction from fetal life onward Journal of American Academy of Child and Adolescent Psychiatry 51 2012 1119 e7 1135 e7
    • (2012) Journal of American Academy of Child and Adolescent Psychiatry , vol.51 , pp. 1119
    • Tiemeier, H.1    Velders, F.P.2    Szekely, E.3
  • 31
    • 79954573845 scopus 로고    scopus 로고
    • Maternal thyroid function during pregnancy and behavioral problems in the offspring: The Generation R Study
    • A. Ghassabian, J.J. Bongers-Schokking, and J. Henrichs et al. Maternal thyroid function during pregnancy and behavioral problems in the offspring: the Generation R Study Pediatric Research 69 2011 454 459
    • (2011) Pediatric Research , vol.69 , pp. 454-459
    • Ghassabian, A.1    Bongers-Schokking, J.J.2    Henrichs, J.3
  • 32
    • 35748965596 scopus 로고    scopus 로고
    • Management of thyroid dysfunction during pregnancy and postpartum: An Endocrine Society clinical practice guideline
    • M. Abalovich, N. Amino, and L.A. Barbour et al. Management of thyroid dysfunction during pregnancy and postpartum: an Endocrine Society clinical practice guideline Journal of Clinical Endocrinology and Metabolism 92 8 Suppl. 2007 S1 S47
    • (2007) Journal of Clinical Endocrinology and Metabolism , vol.92 , Issue.8 SUPPL.
    • Abalovich, M.1    Amino, N.2    Barbour, L.A.3
  • 33
    • 84856608472 scopus 로고    scopus 로고
    • Maternal thyroid autoimmunity during pregnancy and the risk of attention deficit/hyperactivity problems in children: The Generation R Study
    • A. Ghassabian, J.J. Bongers-Schokking, and Y.B. de Rijke et al. Maternal thyroid autoimmunity during pregnancy and the risk of attention deficit/hyperactivity problems in children: the Generation R Study Thyroid 22 2012 178 186
    • (2012) Thyroid , vol.22 , pp. 178-186
    • Ghassabian, A.1    Bongers-Schokking, J.J.2    De Rijke, Y.B.3
  • 34
    • 77956580727 scopus 로고    scopus 로고
    • Maternal thyroid function during early pregnancy and cognitive functioning in early childhood: The Generation R Study
    • J. Henrichs, J.J. Bongers-Schokking, and J.J. Schenk et al. Maternal thyroid function during early pregnancy and cognitive functioning in early childhood: the Generation R Study Journal of Clinical Endocrinology and Metabolism 95 2010 4227 4234
    • (2010) Journal of Clinical Endocrinology and Metabolism , vol.95 , pp. 4227-4234
    • Henrichs, J.1    Bongers-Schokking, J.J.2    Schenk, J.J.3
  • 35
    • 4043174347 scopus 로고    scopus 로고
    • Human fetal and cord serum thyroid hormones: Developmental trends and interrelationships
    • R. Hume, J. Simpson, and C. Delahunty et al. Human fetal and cord serum thyroid hormones: developmental trends and interrelationships Journal of Clinical Endocrinology and Metabolism 89 2004 4097 4103
    • (2004) Journal of Clinical Endocrinology and Metabolism , vol.89 , pp. 4097-4103
    • Hume, R.1    Simpson, J.2    Delahunty, C.3
  • 36
    • 84872166640 scopus 로고    scopus 로고
    • Low urinary iodine excretion during early pregnancy is associated with alterations in executive functioning in children
    • N.H. van Mil, H. Tiemeier, and J.J. Bongers-Schokking et al. Low urinary iodine excretion during early pregnancy is associated with alterations in executive functioning in children Journal of Nutrition 142 2012 2167 2174
    • (2012) Journal of Nutrition , vol.142 , pp. 2167-2174
    • Van Mil, N.H.1    Tiemeier, H.2    Bongers-Schokking, J.J.3
  • 38
    • 33847067518 scopus 로고    scopus 로고
    • Effects of maternal smoking in pregnancy on prenatal brain development. The Generation R Study
    • S.J. Roza, B.O. Verburg, and V.W. Jaddoe et al. Effects of maternal smoking in pregnancy on prenatal brain development. The Generation R Study The European Journal of Neuroscience 25 2007 611 617
    • (2007) The European Journal of Neuroscience , vol.25 , pp. 611-617
    • Roza, S.J.1    Verburg, B.O.2    Jaddoe, V.W.3
  • 39
  • 42
    • 0024357547 scopus 로고
    • The language development survey: A screening tool for delayed language in toddlers
    • L. Rescorla The language development survey: a screening tool for delayed language in toddlers The Journal of Speech and Hearing Disorders 54 1989 587 599
    • (1989) The Journal of Speech and Hearing Disorders , vol.54 , pp. 587-599
    • Rescorla, L.1
  • 46
    • 10444242575 scopus 로고    scopus 로고
    • Verbal and nonverbal predictors of early language problems: An analysis of twins in early childhood back to infancy
    • B. Olivier, P.S. Dale, and R. Plomin Verbal and nonverbal predictors of early language problems: an analysis of twins in early childhood back to infancy Journal of Child Language 31 2004 609 631
    • (2004) Journal of Child Language , vol.31 , pp. 609-631
    • Olivier, B.1    Dale, P.S.2    Plomin, R.3
  • 49
    • 0037080447 scopus 로고    scopus 로고
    • Causal knowledge as a prerequisite for confounding evaluation: An application to birth defects epidemiology
    • M.A. Hernan, S. Hernandez-Diaz, and M.M. Werler et al. Causal knowledge as a prerequisite for confounding evaluation: an application to birth defects epidemiology American Journal of Epidemiology 155 2002 176 184
    • (2002) American Journal of Epidemiology , vol.155 , pp. 176-184
    • Hernan, M.A.1    Hernandez-Diaz, S.2    Werler, M.M.3
  • 50
    • 84871741496 scopus 로고    scopus 로고
    • Thyroxine levels during pregnancy in healthy women and early child neurodevelopment
    • J. Julvez, M. Alvarez-Pedrerol, and M. Rebagliato et al. Thyroxine levels during pregnancy in healthy women and early child neurodevelopment Epidemiology 24 2013 150 157
    • (2013) Epidemiology , vol.24 , pp. 150-157
    • Julvez, J.1    Alvarez-Pedrerol, M.2    Rebagliato, M.3
  • 51
    • 77952638535 scopus 로고    scopus 로고
    • Abnormalities of maternal thyroid function during pregnancy affect neuropsychological development of their children at 25-30 months
    • Y. Li, Z. Shan, and W. Teng et al. Abnormalities of maternal thyroid function during pregnancy affect neuropsychological development of their children at 25-30 months Clinical Endocrinology 72 2010 825 829
    • (2010) Clinical Endocrinology , vol.72 , pp. 825-829
    • Li, Y.1    Shan, Z.2    Teng, W.3
  • 53
    • 0025107457 scopus 로고
    • Detection of at-risk pregnancy by means of highly sensitive assays for thyroid autoantibodies
    • A. Stagnaro-Green, S.H. Roman, and R.H. Cobin et al. Detection of at-risk pregnancy by means of highly sensitive assays for thyroid autoantibodies Journal of the American Medical Association 264 1990 1422 1425
    • (1990) Journal of the American Medical Association , vol.264 , pp. 1422-1425
    • Stagnaro-Green, A.1    Roman, S.H.2    Cobin, R.H.3
  • 54
    • 0025949962 scopus 로고
    • Pregnancy in patients with mild thyroid abnormalities: Maternal and neonatal repercussions
    • D. Glinoer, M.F. Soto, and P. Bourdoux et al. Pregnancy in patients with mild thyroid abnormalities: maternal and neonatal repercussions Journal of Clinical Endocrinology and Metabolism 73 1991 421 427
    • (1991) Journal of Clinical Endocrinology and Metabolism , vol.73 , pp. 421-427
    • Glinoer, D.1    Soto, M.F.2    Bourdoux, P.3
  • 56
    • 0028882548 scopus 로고
    • Maternal thyroid peroxidase antibodies during pregnancy: A marker of impaired child development?
    • V.J. Pop, E. de Vries, and A.L. van Baar et al. Maternal thyroid peroxidase antibodies during pregnancy: a marker of impaired child development? Journal of Clinical Endocrinology and Metabolism 80 1995 3561 3566
    • (1995) Journal of Clinical Endocrinology and Metabolism , vol.80 , pp. 3561-3566
    • Pop, V.J.1    De Vries, E.2    Van Baar, A.L.3
  • 58
    • 84864802168 scopus 로고    scopus 로고
    • Management of thyroid dysfunction during pregnancy and postpartum: An Endocrine Society clinical practice guideline
    • L. De Groot, M. Abalovich, and E.K. Alexander et al. Management of thyroid dysfunction during pregnancy and postpartum: an Endocrine Society clinical practice guideline Journal of Clinical Endocrinology and Metabolism 97 2012 2543 2565
    • (2012) Journal of Clinical Endocrinology and Metabolism , vol.97 , pp. 2543-2565
    • De Groot, L.1    Abalovich, M.2    Alexander, E.K.3
  • 59
    • 36849050817 scopus 로고    scopus 로고
    • Iodine deficiency and brain development in the first half of pregnancy
    • G.M. de Escobar, M.J. Obregon, and F.E. del Rey Iodine deficiency and brain development in the first half of pregnancy Public Health Nutrition 10 2007 1554 1570
    • (2007) Public Health Nutrition , vol.10 , pp. 1554-1570
    • De Escobar, G.M.1    Obregon, M.J.2    Del Rey, F.E.3
  • 60
    • 0003492536 scopus 로고    scopus 로고
    • Health Organization United Nations Children'S Fund W. International Council for the Control of Iodine Deficiency Disorders 3rd ed. WHO Geneva
    • World Health Organization United Nations Children's Fund International Council for the Control of Iodine Deficiency Disorders Assessment of iodine deficiency disorders and monitoring their elimination 3rd ed. 2007 WHO Geneva
    • (2007) Assessment of Iodine Deficiency Disorders and Monitoring Their Elimination
  • 62
    • 84856782840 scopus 로고    scopus 로고
    • Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Bethesda, MD: National Library of Medicine
    • Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). Thyroid therapy for mild thyroid deficiency in pregnancy (TSH). Bethesda, MD: National Library of Medicine. Available from: http://www.clinicaltrials.gov/ct/show/NCT00388297.
    • Thyroid Therapy for Mild Thyroid Deficiency in Pregnancy (TSH)
  • 63
    • 84864818334 scopus 로고    scopus 로고
    • When thyroidologists agree to disagree: Comments on the 2012 Endocrine Society pregnancy and thyroid disease clinical practice guideline
    • O.P. Soldin When thyroidologists agree to disagree: comments on the 2012 Endocrine Society pregnancy and thyroid disease clinical practice guideline Journal of Clinical Endocrinology and Metabolism 97 2012 2632 2635
    • (2012) Journal of Clinical Endocrinology and Metabolism , vol.97 , pp. 2632-2635
    • Soldin, O.P.1
  • 64
  • 65
    • 84874781557 scopus 로고    scopus 로고
    • A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function
    • E. Porcu, M. Medici, and G. Pistis et al. A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function PLoS Genetics 9 2 2013 e1003266
    • (2013) PLoS Genetics , vol.9 , Issue.2 , pp. 1003266
    • Porcu, E.1    Medici, M.2    Pistis, G.3
  • 66
    • 79952624880 scopus 로고    scopus 로고
    • Use of genetic markers and gene-diet interactions for interrogating population-level causal influences of diet on health
    • G. Davey Smith Use of genetic markers and gene-diet interactions for interrogating population-level causal influences of diet on health Genes and Nutritions 6 1 2011 27 43
    • (2011) Genes and Nutritions , vol.6 , Issue.1 , pp. 27-43
    • Davey Smith, G.1
  • 67
    • 84856790058 scopus 로고    scopus 로고
    • The debate over thyroid-function screening in pregnancy
    • G.A. Brent The debate over thyroid-function screening in pregnancy New England Journal of Medicine 366 2012 562 563
    • (2012) New England Journal of Medicine , vol.366 , pp. 562-563
    • Brent, G.A.1
  • 68
    • 0033539361 scopus 로고    scopus 로고
    • Should all pregnant women be screened for hypothyroidism?
    • V.J. Pop, A.L. van Baar, and T. Vulsma Should all pregnant women be screened for hypothyroidism? The Lancet 354 1999 1224 1225
    • (1999) The Lancet , vol.354 , pp. 1224-1225
    • Pop, V.J.1    Van Baar, A.L.2    Vulsma, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.